Conserved Protein Domain Family
Tektin

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pfam03148: Tektin 
Tektin family
Tektins are cytoskeletal proteins. They have been demonstrated in such cellular sites as centrioles, basal bodies, and along ciliary and flagellar doublet microtubules. Tektins form unique protofilaments, organized as longitudinal polymers of tektin heterodimers with axial periodicity matching tubulin. Tektin polypeptides consist of several alpha-helical regions that are predicted to form coiled coils. Indeed, tektins share considerable structural similarities with intermediate filament proteins. Possible functional roles for tektins are: stabilization of tubulin protofilaments; attachment of A and B-tubules in ciliary/flagellar microtubule doublets and C-tubules in centrioles; binding of axonemal components.
Statistics
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PSSM-Id: 460827
Aligned: 135 rows
Threshold Bit Score: 186.215
Created: 21-Mar-2022
Updated: 13-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ESN92457      16 WKANQMNVLLGAELDRASAerLTNETKRYIDEMRQASQHSDQRAEFSQERRMEEVRYWQNELNMKLDQIKLAINDLSSID 95 
XP_395193    122 WVQNQLRLYNESDSNRNFSenLRQDTVRIMRETDEKVQKGQIETGRKLGERITDTTFWRNEMASELERLIIENAKMQECR 201
EGI69111      93 WIQNEIKLYNEANANRNYSekLRKNNACLMREVDEKVKEGQTESGRKLGERITDVTFWRNEVASELERLIIENGKMQDSR 172
ESN91809     105 WCLSNQCNYQTSNRVRCASefLRHNSLHTASELEEKSQKSQIDSNNKLSERIQDIMFWKCELQAEMDKMLAEMDVLLKSR 184
ESN98160      72 WNICNVVNGVVTEKVVAGSeeLRGNATRLCKELDDKTRRTQEDVSRKLGERIGNIEQWKSEVKAEIDDMVSEIDALDKAK 151
CDS43459     116 WFDSYNRLLQANDLAQKNSdcLALDSKRLKGELADRAKTNQNDSTRRLGDRICDTAFWQSEVDSEIAKMKQDIDDLIRAR 195
XP_009028491   6 WKVSNGSLLNASDRIKAGSelMRAEALRVCEDACEKTRKGSRDVTKRLDDRAKDIDHWKKELEKELNDLVNETKNLEKIE 85 
CAP32895     233 CNIFRTEYDDPIEIVR--------MARLAVKEANMRATRMQGQTTQQLMQRVKDLKYWSGEIDRELADVKEEHDDLLRCY 304
XP_001622655  12 WKNASVRNIRLGQTVVNRSdkAC-DMGQQLDPLPSLRDTSIQQSNARIHAYVRATRAVLVKLQENLLDTNEEIKSLIKGK 90 
XP_001697824  36 WTLESVEQMGLGATENRMSstLRDASSQLQAVASATVANDISIVDRALTTKLSQTESLKNMLETCLAEVISEIAELLSTK 115
ESN92457      96 RRLDKAMDSIKENCHIVHKCLEARKRRKRI-YLVYDPAEKQLCKEREIIEGVLALHCKTKSQVNDQLRLLRKLRHDIEKD 174
XP_395193    202 RNLQITIQSLEGQLHIAQECLYYREARTGS-DLVHDQAEHALLKEVEVVRNCENKLEHFTDKCNNQLTNGRAVQNQLEID 280
EGI69111     173 RKLQTVIQSLERPLHITQECLYHRESRKGI-DLTHDEVEKDLLEEVEIMRNCEKKLKQIMDKCINQLTNGRAVQHQLQID 251
ESN91809     185 SCLEREISELNNTLYIDQECLYNREKRQGI-EMVHDDVEVSIIQEIDLLKRVQEDMRNIMNDINQTLASVIAAYHELEKD 263
ESN98160     152 TCLAKTQLDLDVPLKIAEECLYSREKRRGI-DLVHDEVEKQLIKEIDILKSNQENSRRLVEDAAAQIALNRAALHELEKD 230
CDS43459     196 RVTEKLLAETENHLHVTQECLYNREKRQCT-DLVHDDVEKRLIEEVNTVRCIQDELRRLTDNAKTQEQLNRAALHDLEAD 274
XP_009028491  86 NCVSNALAYTDMPLEMILKCIEERKNRKEI-EMVDDDVDEELRKELENIQSVRSALGNHLFDVQGQLQRNKHIQNLLSDN 164
CAP32895     305 RRLQLCLDITGRATRCNESCLAVRRKKVQVgDHTSDRVDMELHKEKELMSETVKQMKEVGERVERQLEVNQAARKNLLRD 384
XP_001622655  91 ETLEKTLEHIRKDIVLNNKSTSIRKTRPPR-EKSPDGADDLLTAERKHLLKLKRILEAQLRSAQKQLQVLDANRKRLRAA 169
XP_001697824 116 KRLEERNGKVQAKIGVNSNRMQVRSSRPPR-EMTMDEVEKGLIKQQGMLGSFSDRVARAVAQVDREVAQLEAVRAKLEAD 194
ESN92457     175 VLMKLTNFDVEMESSEIRAKKAAIAA--YNYDPNCEG-------AELcpckleghccqktkkpgglssISDWLTQVKSVH 245
XP_395193    281 IKNKETALGIDITCHQMNNFSRGLKY--YGGIEKYDPs------VTE---------------------AESWIEASNNLV 331
EGI69111     252 LQNKETTLGIDNVCHQMNNLTRGLQY--YGGIERYDPs------VIT---------------------PEFWEEATNSIV 302
ESN91809     264 SADKFVALNIDNNAIKMKNTSRGIYY--YDCIERVDNs------QSV---------------------PETWAKYTDDNI 314
ESN98160     231 LDDKLVALNLDNNCHRMKDSTRSLHY--YDGVHRVDNs------TSI---------------------PVTWAQFSADNI 281
CDS43459     275 KARKFRAIQLDESAHSMHNSSAHISY--YEGVECIDQt------QSV---------------------PETWNKQVSDLV 325
XP_009028491 165 IMDKHRANVIDKKCRDMKNTSANLKF--PPGIESANTt------ISD---------------------PQAWVEQAVNLI 215
CAP32895     385 LTLKQEAISLDHKSVAIGADG-------TKTVVRTPDgdrldfrEGAplqr--------------mseYSEWIENTGNNL 443
XP_001622655 170 VQERSRVMDLICHAVSSVRGAGIKDQieRPSTPEVEP-------------------------------LGPYTPECARVI 218
XP_001697824 195 LRDKTEALRVDEAVLSIPTD-PTVEGtlSPTFRRGAAdc----pPKT---------------------PHTWVRNTEDNL 248
ESN92457     246 TEAEKQRQNAANLTSIADSSLKQTKDDLQNIKVATDDAFRERIYELRDHKAKMEDHLQKVVKQIQEMETTSQSLINEINI 325
XP_395193    332 KKSQTEREKSNQLRSDIEIAINAVGHEMWEAWGNTNNALARRAAEMLEAKEKLQIHLHKIQQEIFEVEKNLQLIQKAITD 411
EGI69111     303 KKSQTERAKSHQLRNDIDNVINAVVHEICEAWTETNEALDRRIAEMLEAKEKLQTHLHKIQEEIFDVEKNVALMQKTIAD 382
ESN91809     315 KRSMQERKASRELRNKVEEMLTITAERLVTAWNNVNSAFSDHIEELEKAKYKIQAHLSKILEEIFNTETSIELLKKSIEE 394
ESN98160     282 RRSRAERLRSRDIRKSIEGLCNGVMDEVNDQWNRVNDALEDRLKEYADAKNKLQYNLTKTLQEILDQEKAIELLRVSIRE 361
CDS43459     326 QRSQSERAASRMLRERIAKGIAHASKTLSDIWEAVNAAFAQRIREFTDARNQLQASLGKTLQAIFDTEKEIEDLKKAIKD 405
XP_009028491 216 QASQAERTKSRSLDQDINRLVGQLSGSLVKHWISTNEVLSFRIEDHLRAKHKLETHLRELSNELIDAQKTTEYLKKNIRD 295
CAP32895     444 NYAARARVHSRKIGQKLCQSLRELASQLRTEAIAVEALLKDSVRNWQEWKDNLHSQVNGKDKEIKNADGAIEEISFSLKQ 523
XP_001622655 219 SEAADARQRSSTLRKEVAEAIEQTIKLQKAAHNSVNDGLTQKVAETVSMRQHLQVGGGELRMSIHRSKRWYNATEMALGY 298
XP_001697824 249 RNAHHWLADSARLRKAIAHAVANSRATEHDVANRLNENMLAKVAATRNLREDLQAQLEKVREEQARAKGQRSALTSALDD 328
ESN92457     326 YTKKLTFEQSKIQPLQNCPQNLLDSEEV---LVTNYCTNKGNVEKLKDNLACVQCSLKSLQCRKVEVESDLKLCTEALTI 402
XP_395193    412 KSSALKVAHTRLESRTHRPAAELCKDYAqlrMIEEVETINSTIHDMNLKLQRFEAQHQQLLRTRSNLETDLKSKVDALFI 491
EGI69111     383 KSPVLKVVHTRLEARTHRPDNELCKDDAqlrMNKEVEDINKIVNDLNMKLQQSEAQHQQLLRTRSNLESNLKSKIDALFI 462
ESN91809     395 KAPYMKVAQTRLEARNHRPNMENTRDHVhnkLVEEVYEVCETIDKLKAKLRESENALQQLLRTKASLQHDLDLKLLSILI 474
ESN98160     362 KDSPLQLAQTRLVTRLRRPNMETCKDSAqhrLVGEVYEINESVDILRAKLRQSENALQHLLKTKLSLEHDLDIKNNSIVI 441
CDS43459     406 KEEYLKTATSRLNTRLLRPEVENCRDPAmihLICEVKQLKGAIEELTKQLRRAEGVLQELLHLRTAKEGELACKNNSLFI 485
XP_009028491 296 KNAPIQLAQTRLHVRANRLNMEACLDPAhekLVKELTDLDENVDELMKKLREAEYVEGHLARSIKSLQHDLNLKNHSLFI 375
CAP32895     524 KSGPLQVALSRQNQRGLRPGIELCNDKAqhaLHQELMMLKGTFLSLENQLDKAKESRKKLENDRDKLQRKLDICDHNLTI 603
XP_001622655 299 TLGPVAYSDLTTREHLDRPTVKIFQRHPgnqL-PEAREIGRGGQGLQESLNATARNIGLLKLTKDRIDSDASDKHHASLI 377
XP_001697824 329 KRGPLAQARERLAVRKARPCRENVNDEVeaaLAKEVAHLAAVTQQLSVKVAAVDREIAALDATAAQLESNIADKDDALRV 408
ESN92457     403 DDYECLPMRQSIK 415
XP_395193    492 DREKCMGMRRSYP 504
EGI69111     463 DREKCMGLRRSCP 475
ESN91809     475 DREKCMGLRRSYP 487
ESN98160     442 DREKCLGIRRNYN 454
CDS43459     486 DRECCLALRTQWP 498
XP_009028491 376 DRDKCLSLRKTFN 388
CAP32895     604 DNEILRQIRSSYP 616
XP_001622655 378 DS-NVVRDRRRHA 389
XP_001697824 409 DE-RVVLLDGRIN 420
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