Conserved Protein Domain Family
SRA1

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pfam07304: SRA1 
Steroid receptor RNA activator (SRA1)
This family consists of several hypothetical mammalian steroid receptor RNA activator proteins. SRA-RNAs likely to encode stable proteins are widely expressed in breast cancer cell lines. SRA-RNA is a steroid receptor co-activator which acts as a functional RNA and is classified as belonging to the growing family of functional non-coding RNAs.
Statistics
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PSSM-Id: 429397
Aligned: 7 rows
Threshold Bit Score: 224.32
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_004076694  74 SLAPPPRSIAPPPlssvgfPPAGvaTPLPQHEPmnpqRDTGVSQSEPNLELVMSVLNRALQACRVSVTDYVCNEVEKRLR 153
XP_005461833  75 PAGPPPGAVATPP------PPHL--GQMRTKRE----AAISQSESEPEVEGVMSVLNGALAACRRAVKAQVCNDVAKRLH 142
1_pfamImport   1 PMAPPPPSDLTPP------PPPLgpGPLRSQRD----KDSSHSEAEPDVEGLMLVLNQALDACRPTVKDQVCSDVAKRLR 70 
2_pfamImport   1 PMGPPPASAAPPPldp-acPPPT--GLVASRHPagtaKGQPEADTEPDMDSVMSVLNLALNACRQAVKEQVCSDV-KRLR 76 
XP_003220029  76 LPASSPCPVGLPP------PPSGlpVSCPQVDA----TNLLVSE-DCVVEDVLSPLNEALDNCRKTLRKQICDDIGKRLA 144
XP_002816012  74 SMGPPPPSSKAPR------SPPVgsGPASGVEP----TSFPV-ESEAVMEDVLRPLEQALEDCRGHTRKQVCDDISRRLA 142
XP_017197055  94 PVGPPPPS-KAPG------PPPVesCPSSCVVP----TSSPVIEPEALLEDVLRPLEQALKDCHGHTRKQLCDDISRRLV 162
XP_004076694 154 LLEDSWRSGKLSFPVKRRMEVLARELQTGNWSSADEVHRSLMVDHVTEVSQWMVGVKRLIAEVQNLSPELLETLKNP 230
XP_005461833 143 LMEDSWRSGRLSLPVRRRMDTLSAELQKGRWDAADDIHRSLMVDHVTEVSQWMVGVKRLIAETRNLSPELLEPLQKV 219
1_pfamImport  71 LLEASWRSGTLSLPVRRRMDTLSLELQSGRWDSADDIHRSLMVDHVTEVSQWMVGVKRLIAETRNLNPERLEPLQKP 147
2_pfamImport  77 LLEDSWKGGKLSLPVRRRMDTLSQELRAGHWDAADKVHLSLMVDHVTEVSQWMVGVKRLIAETRKLNPELLEPLKKS 153
XP_003220029 145 ILQQMWEQGKLSAPVRKGMRILIQEFKSQHWDAADEIHRSLMVDHVTEVNQWMVGVKRLIAETRNLPTDNLATIEHE 221
XP_002816012 143 LLQEQWAGGKLSIPVKKRMALLVQELSSHQWDAADDIHRSLMVDHVTEVSQWMVGVKRLIAEKRSLFSEEAANEEKS 219
XP_017197055 163 LLREQWAGGKLSVPVKKRMALLVQELSSRQWDAADDIHRSLMVDHVTEVSQWMVGVKRLIAEKRSLSSEEAAKEEKS 239
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