Conserved Protein Domain Family
CysJ

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COG0369: CysJ (this model, PSSM-Id:223446 is obsolete and has been replaced by 440138)
Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
Statistics
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PSSM-Id: 223446
Aligned: 34 rows
Threshold Bit Score: 274.295
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
17989356   26 ALSVFPAMERLSAPQAETGLSVADLMARiqanyPAVEQVRrTPSGKITAYWfDDGAQAAVIDPATGKSVAPANPNRLEQW 105  Brucella melitensis
15605162      --------------------------------------------------------------------------------      Chlamydia trachom...
19173560    1 -----------------------------------MIPILyGSQTGTAIYVsNLIARAIMHGYDAKTIYNLDAFLYSPGQ 45   Encephalitozoon c...
19113958    1 ---------------------------------------------------mKNSHIYILYGSETGTAEGLAESLFRSLT 29   fission yeast
19114568    1 MISHVLVKDTSCLKVRTSYKCFVKYFPK-----CSVQSSFhSYDELAFSRRlYNLPRTLLNSRYYSNHSHGLVHGSKSPP 75   fission yeast
1175420     1 ----------MAPSVATSLKAEILPSPR-----TSSPSSN--FKTCVSNE------NGCINCRCSPSEPH---ESANVDE 54   fission yeast
8488993   383 SLVSAYRTDKSRSVAFRPLFDNLTLAGVr----FTVAQVStANAVLTDVVKdVDADITILTTDRLPLHYRVLAKAAEHSI 458  fission yeast
6325305     1 ------------------------------------------------MSS--SKKIVILYGSETGNAHDFATILSHRLH 30   baker's yeast
20138171      --------------------------------------------------------------------------------      Nostoc sp. PCC 7120
2498067       --------------------------------------------------------------------------------      Synechocystis sp....
17989356  106 LKGlHRSLFLGDSGRIVMAIG----ALiMLGLSISGAFLIARRTGGW--------KNWFKPLRGAasgrlhtevaRIAVL 173  Brucella melitensis
15605162      --------------------------------------------------------------------------------      Chlamydia trachom...
19173560   46 KDAcLVMEMDLLDIEKILDID--------LIIFVCSTHGDGAEPFNM--------TKFWSFLSRDd--------lPSTIL 101  Encephalitozoon c...
19113958   30 RMG-YDVLVNSMDDFNLENLLr-----pLQCVFICSTTGQGEMPLNM--------RERIITYRFNwask--kldsRLRQL 93   fission yeast
19114568   76 SS---QFLVPSFLQFNGQLKA----LC-NNSAFQALPIKLSDLQKHW--------PSLKPHPLPP----------KRVSL 129  fission yeast
1175420    55 SV---NKLSKTFSKLS------------LNPTFQALNMDLGLLHENI--------TLDRIPKVPE----------NHVSL 101  fission yeast
8488993   459 CLLqSSIAPDEATKKLPYEFIadalEKgVKLVLIDPKKFAIDASNLPl------lVSFIQLVKPGl---------GVDEA 523  fission yeast
6325305    31 RWH-FSHTFCSIGDYDPQDIL-----KcRYLFIICSTTGQGELPRNVnalkgerpVTFWSFLKRKn--------lPSNLL 96   baker's yeast
20138171    1 ----------------------------MSNQGAFDGAAN-VESGSR--------VFVYEVVGMR----------QNEET 33   Nostoc sp. PCC 7120
2498067     1 ----------------------------MYSPGYVATSSRQSDAGNR--------LFVYEVIGLS----------QSTMT 34   Synechocystis sp....
17989356  174 GLLLSSTTAVWMSASTfDLLPKSPVVAEPTGVSGETGMKPALIAKLEetp------vsSFKELSFPYPGDATDMFVLKTD 247  Brucella melitensis
15605162    1 ------------------------------------------------------------------------MSLFSKFK 8    Chlamydia trachom...
19173560  102 SHLSFAVFGLGDSSYE-KFNYCSKRLFNRLRMLGARPVIRRGSGDSQdr--------eGFLSDFRPWLLELTAYLRTYIS 172  Encephalitozoon c...
19113958   94 GAQSFSSRGEGDEQHPdGVEGVFAYWCNHLYSQLAAIKTPSRPAFG------------EFDLLPPSFQIIIDESLGCKVK 161  fission yeast
19114568  130 G-IPSISNPPVDTVIS--DSPTSPHPPSFVQPHPPYGIFAAPILDVR-----------VLTNPGAVKRTYNLCLDISKYP 195  fission yeast
1175420   102 IDIDEARAKEDPNFQI--HSTPSRMPPHYVQPHPPFSVFPAPILDVR-----------ELTKPGAVKRVFHFELDVSNYP 168  fission yeast
8488993   524 LAVLAKQNNLTDTNLKdAVDSLKQSLS--FINLDASALKDREPSEKEl----------PSTAKETSFAPNAVKTLDEDIT 591  fission yeast
6325305    97 NHIQTAMLGLGDSSYPkFNYGIRKLHQRIVTQLGANELFDRLEADDQamagsnkgtglGIESVYFEYEKKVLSFLLSKYP 176  baker's yeast
20138171   34 DQTNYPIRKSGSVFIRvPYNRMNQEMQRITRLGGKIVSIQTVSALQQl----------NGRTTIATVTDASSEIAKSEGN 103  Nostoc sp. PCC 7120
2498067    35 DGLDYPIRRSGSTFITvPLKRMNQEMRRITRMGGKIVSIKPLEGDSPl----------P-------HTEGIAKPSQSEG- 96   Synechocystis sp....
17989356  248 RGTGYLDQgtgavldwhDYTVWQRisqtvkMLHTGKGAALLGIILGLASLTVPflgitgivlwfaglrgrprirdnAAAG 327  Brucella melitensis
15605162    9 AQ--------------------------------WMFLHSRELCSSTSDIGNT-----------------------CSDP 33   Chlamydia trachom...
19173560  173 RPCTDFIS--------------------------TQPKRYVSRLVEKRVLTPD-----------------------DHFQ 203  Encephalitozoon c...
19113958  162 GFED--N-----------------------NIVRHSRGKIEATLVHNKRISNI-----------------------KHWQ 193  fission yeast
19114568  196 LL----------------------------EGKDWKIGGSFGIMPPNSDAEVL-----------------------HLAH 224  fission yeast
1175420   169 LP----------------------------EGEEWMVGGSFGVMAPNNEEDVD-----------------------ELLQ 197  fission yeast
8488993   592 PQSSNWQTva------kQIIFPEAykkkdaLRPDVSEKVFTVHVRANKRLTPA-----------------------EYNR 642  fission yeast
6325305   177 NRKVNGQIikreeldpeVYLEPASylqlsdEHANEKFTSTKVIFEGDESLKVGrvnink------------ritseGHFQ 244  baker's yeast
20138171  104 GK---------------------A---------TPVKTDSGAKGFAKPPAEEQ-----------------------LKKK 130  Nostoc sp. PCC 7120
2498067    97 ---------------------------------------SGSEAVANPAPES---------------------------- 109  Synechocystis sp....
17989356  328 KAETIVLVGSEggstwgfaatlHAALREAGQSVHVGPMSSFnparygkaQRILIFAATYGNGDAp--ASAkgflDR-Laa 404  Brucella melitensis
15605162   34 VFQVLCNPVRS------------EISYKVGDSLGVFPTNPS--------ILVDSVLDALQYGPR---SPV----VS-Rh- 84   Chlamydia trachom...
19173560  204 KIVEFVFDIPD------------YKEFFPGDCLSLLPENYN----------YREFMSYNGIGDGd--------------- 246  Encephalitozoon c...
19113958  194 DVRHLAFKIPN------------FERWKPGDVAVLYPWNDD--------MSVNSFIECMGWESIk-ySPLiissNV-Aer 251  fission yeast
19114568  225 LLKIPQHELYVt----------KVLRTNGGRWPTIWGEDKPr-------CLYTSLYHIFKWCSD---FIS-----K---- 275  fission yeast
1175420   198 LLHINPDQADAp----------VLLKTDGGRWPTIWAEDTPr-------ELVTTRRELLKWTVE---FMS-----V---- 248  fission yeast
8488993   643 NIFHIEFDLGD-----------SGLTYDIGEALGVYGVNNK--------THVHDFIEEYGLDAN---ELIhv-pSIqHpg 699  fission yeast
6325305   245 DVRQFKFSNVDk----------IQENYEPGDTVTIYPCNTD--------EDVSRFLANQSHWLEiadKPLnftsGVpNdl 306  baker's yeast
20138171  131 DNKGNTMTQAK--------------AKHADVPVNLYRPNAP---------FIGKVISNEPLVK----------------- 170  Nostoc sp. PCC 7120
2498067   110 -NKTMTTTPKE--------------KKADDIPVNIYRPKTP---------YIGKVLENYPLVR----------------- 148  Synechocystis sp....
17989356  405 lpkspAAPLAVLGFGDRSFPDYCAFaKAIADgarakgwkelipfETVDRQSTQDF---ARWGRDLGaaigIKLELVHQP- 480  Brucella melitensis
15605162   85 ----aDSVLPLHEFLTSYVDLDKIP-KSLRP-------------FFPGDLDDTWS---LAEAI----------------- 126  Chlamydia trachom...
19173560  247 -----LDGVSSVWMLQNVVDFNSQPhQPFFF-------------ALRHFLGQKNRteeEILLKIEEiaqdYDLYHDYVIr 308  Encephalitozoon c...
19113958  252 klpwfPNILNVFNLVKYVLSIHSVPsRTFFE-------------MASHFSNNKMH---KERLQEFSsyknIDDYYDYTTr 315  fission yeast
19114568  276 -----PPTKSLIRLLAEHTLNPVEK--SVLL-------------ALSDFRQDESY---CRICTQSC-------------- 318  fission yeast
1175420   249 -----APKKQLIRLLAEYAKDDTER--QVLL-------------FLVSRLGQRAF---CDLRDHN--------------- 290  fission yeast
8488993   700 ----hWETRTVFQALCQNIDIFGKPtKKFHE-------------QLLEFETDEKE---RADLQILIspagAPDFKRRAEv 759  fission yeast
6325305   307 kdgglVRPMTLRNLLKYHCDFMSIPrTSFFLkiwt-----fatdVTKMERGQEQLndqREKLRQFAtdqdMQDLYDYCNr 381  baker's yeast
20138171  171 ---------EGGIGIVQHIKFDLTG-----G-------------NLKYIEGQSIG------------------------- 198  Nostoc sp. PCC 7120
2498067   149 ---------EGAIGTVQHLTFDLSA-----G-------------DLRYLEGQSIG------------------------- 176  Synechocystis sp....
17989356  481 -VIPAVAALTLVSRrdygADVQAPTAILRFALPKPTFWQQLSGAGFSR---FEAGDLLGIVPEGSAvpRFysLASGSRDG 556  Brucella melitensis
15605162  127 -LVYQ----P---------RIPFEEFIRSAMPLLPRFYSIASSPTCSH---GKLELLVRCVSFQGK--TQ--LRYGLCSA 185  Chlamydia trachom...
19173560  309 aRRTVFEVLKDLR-----IKVDIGFLKSFVPAMYPRFFSVTKKKGLY-------HITVAIVRYTTFlsEP---RRGVCSE 373  Encephalitozoon c...
19113958  316 pRRTVLETLQEFKS----VQIPIEYALDAFPVIRGRQYSIANRCDNST---GILELAVALVKYQTIlkSP---RQGICSR 385  fission yeast
19114568  319 --VTLPDILEAFPS----CHPPVDHLISALPQLMPRWYSISNDPSLAN---KRLEMAFTVQEYHSP--NGq-SRTGICTG 386  fission yeast
1175420   291 --VTLITLLKAFPS----VQLPLDHLLTVLPQLMPRWYSLSNDPKVSN---NVLEFAVTVVEINKV--EGg-TRSGIGSG 358  fission yeast
8488993   760 dMLTYADVLKEFKH----AKLTAAQIAQIVPVIKRREYSISSSQKKHN---DSVHLLVVVVGWKDGm-GR--DRYGQCSH 829  fission yeast
6325305   382 pRRSILEVLEDFIS----VKLPWKYVLDYLPIIKPRYYSISSGPGDPN-----IELTVAIVKYKTI--LRk-IRRGICTN 449  baker's yeast
20138171  199 --------------------IIPPGVDKNGKPEKLRLYSIASTRHGDDvddKTISLCVRQLEYKHP--ESgeTVYGVCST 256  Nostoc sp. PCC 7120
2498067   177 --------------------IIPPGEDDKGKPHKLRLYSIASTRHGDFgddKTVSLCVRQLEYQN---EAgeTVQGVCST 233  Synechocystis sp....
17989356  557 FVEIVVKkhpaglcSGQlfelqpgdTMRAFLRRNANFHAGKGR--TPLILVGAGTGIGPLAGIVRANRQHRP-------- 626  Brucella melitensis
15605162  186 FLCKDLQ-------EGE--------SFRGFIQPTRHFTLEQKNfgKPLIMIGAGTGIAPYKGFLQHRIYHQDvg------ 244  Chlamydia trachom...
19173560  374 YLMSLSL--------ND--------VIKIGVERS-NLYFDSDK----LLFVCTGTGITLPRACVNEFKDKEIv------- 425  Encephalitozoon c...
19113958  386 WICDLHEn------T----------SFNIDILPG--FLNLSYQsnKPLIMVGPGTGVAPLRALIQERIYNGLke------ 441  fission yeast
19114568  387 FLEDLALafl--kaRHDgslankkfTVPMFRGVQQNPFAKEFHndGPMCLIGAGVGIAPFRGFVQRRLANAAct------ 458  fission yeast
1175420   359 FLKRLALrfl--ngERDl-------VLPMYRGLHKNAFATHFAsdGPMCLIGAGVGVAPFRGFVQRRLTNATca------ 423  fission yeast
8488993   830 YLSNLKV--------GE--------PLCVAVKTS-VMKLPTSPl-KPIVMAGLGTGLAPFRAFLQFKEWQRMqgie---- 887  fission yeast
6325305   450 YIARLQE--------GE--------QIRYKLQNN--HIIKKEFlnKPMILVGPGVGLAPLLSVVKAEISKDIk------- 504  baker's yeast
20138171  257 YLTHIEP--------GS--------EVKITGPVGKEMLLPDDPe-ANVIMLATGTGIAPMRTYLWRMFKDAEraanpeyq 319  Nostoc sp. PCC 7120
2498067   234 YLCNIKE--------GD--------DIAITGPVGKEMLLPPDEd-ANIVMLATGTGIAPFRAFLWRMFKEQHedyk---- 292  Synechocystis sp....
17989356  627 ----VHLFFGMRHPESDFFYHEDLQE------------WQGEGRLQNLTTACSRV---------------HNPSYVQDAL 675  Brucella melitensis
15605162  245 ---sNILFFGERFEKSNFYYRDFLQE------------LIVSG-KLQLFTAFSRDs--------------ESKLYVQNVI 294  Chlamydia trachom...
19173560  426 ------IFYGFRYKNKDFLYPDEWT---------------G--RNVRMFTAASRD----------------DKVYVQDVF 466  Encephalitozoon c...
19113958  442 ----nLLFFGCRNKSMDFLFEKDWEK------------YTEEG-TLKLFCAFSRDq--------------EKKKYVQHSI 490  fission yeast
19114568  459 --gkVWIIQGCRDQKLDELYHGEWN-------------TVPGHHKNPK--CRAKKlvve--------srnGRREYVQDAV 513  fission yeast
1175420   424 --gkVWVFHGCRDQELDELYHGEWENplqkssdddassTVSQQTETEMDSFEVKKdgtsgpnhlvvesrsHQHAYVQDEI 501  fission yeast
8488993   888 -sgdILLYLGSRTQREEYLYGEDWEA------------YHSANLLTHIGQAFSRDq--------------PYKIYIQDVM 940  fission yeast
6325305   505 ------LLFGCRYKDKDYIYKDMLED------------WFRKG-KIALHSSFSRDee-----------nsPGVKYVQDYL 554  baker's yeast
20138171  320 fkgfSWLVFGVPT-TPNILYKEELEEi-----------QQKYPDNFRLTYAISREqkn----------pqGGRMYIQDRV 377  Nostoc sp. PCC 7120
2498067   293 fkglAWLIFGIPK-SENILYKDDLEKm-----------AAEFPDNFRLTYAISREqqn----------aeGGRMYIQHRV 350  Synechocystis sp....
17989356  676 RKDAAEIARLVNKG-ARVMVCG-GRDMAAGVSEALADILAPAG---------LTPAVLKAEG--RYVEDVY 733  Brucella melitensis
15605162  295 EQQKELIQEVYEQE-AFFFVCG-KKILGTEVKRALEQILGp-----------KAVRELIAQK--RLVSDVY 350  Chlamydia trachomatis
19173560  467 RK-SP--VEDVDQY--LIFVSG-NSRLNREVKKLLEDVYG--------------------KRi-VFQSETW 510  Encephalitozoon cuniculi
19113958  491 QENGELVYNLLNEKdGMFFVSGsSGKMPSSVKDAIAGIVSKYSgcsi-sdgySFVTSLEKKN--RYYQETW 558  fission yeast
19114568  514 RRHGDVIWDVLSHKnGRIYLCGsGNSFVSEIEKALMDVAMKYGklsk-eeaqKELKNWQKPMncKLIKEVW 583  fission yeast
1175420   502 RHRGDIVWSVLSHPhGKVYLCGgKKGFLDGVENALIDVCVQYGkmsr-leatQQLALWQSPLnlKYIKEIW 571  fission yeast
8488993   941 RSTKDMLKKALMDEgGSFYLCG-PTWPLPEITSVLEEVIQSSYdepv--darKIIEQWKEER--RFVIEVY 1006 fission yeast
6325305   555 WRLGEEITNLVVNKdAVFFLCGsSGKMPIQVRLTFIEMLKKWGnfsdeetakKYLKEMEKSD--RYIQETW 623  baker's yeast
20138171  378 AEHADELWQLIKNEkTHTYICG-LRGMEEGIDAALSAAAAKEGvt-----wsDYQKDLKKAG--RWHVETY 440  Nostoc sp. PCC 7120
2498067   351 AENAEELWNLMQNPkTHTYMCG-LKGMEPGIDEAFTALAEQNGke-----wtTFQREMKKEH--RWHVETY 413  Synechocystis sp. PCC 6803
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