Conserved Protein Domain Family
Relaxase

?
pfam03432: Relaxase 
Relaxase/mobilization nuclease domain
Relaxases/mobilization proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalysing trans-esterification.
Statistics
?
PSSM-Id: 367497
Aligned: 17 rows
Threshold Bit Score: 168.71
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q9XAW2        13 KTSFKSLAKYACErdhidp---etgaveRRECSTETNc--lDKDTAWREMKAVSDMNG--------RV---------KDP 70  Pseudomonas alc...
WP_007560590   8 ISHGVAALEYDLAkeing------qavaTEIARHELYg--cTGAEMVQEMKPYHIDFP--------NVk-------nNCL 64  eubacteria
P06668        17 TKTLQQIINQLEYlsrkg-----klelqRSARHLDIPvppdQIRELAQSWVTEAGIYD--------ESqsdd--drqQDL 81  Agrobacterium t...
Q9ZIP2        14 KSSLYNILKYVGSqnek-------ekddRVYKTTGINvs-dDYKKAFKEMMLTKELHC--------KLd--------GRQ 69  Fusobacterium n...
Q48665        35 EDHLTNLFPYISNpdktmskqlvsghgiTNVYDAANEf--iATKKLKALSKGTDFNFDpqtgkvrfNVesle--knnAVL 110 Lactococcus lac...
Q54883        12 KNYRSKLIKYILNpsktknltlvsdfgmRNYLDFPSYk--eLVKMYNDNFLSNDTLYE--------FRhdrqevnqrKIH 81  Streptococcus p...
Q56424         8 GTSFSGCVCYVLRed-----------ksKLLEAVGVEg---TPEQMAEQFELQTLLND--------KV---------KNT 56  Bacteroides fra...
Q4FIJ3        62 NESFVALVDVMKDgcew-------vnfyGVTCFHNCTs--lETAAADMEYIARQAHYA--------KDd--------TDP 116 Salmonella ente...
KFL47726       6 KSDFAELVKYITDeqgk-------terlGHVRVTNCEa--nTLPAVMAEVMATQHGNT--------RSe--------ADK 60 
Q00192        13 KSDFAGLANYITDaqsk-------dhrlGHVQATNCEa--gSIQDAITEVLATQHTNT--------RAk--------GDK 67  Escherichia coli
Q9XAW2        71 VYHFTVSWPAHEkPTD------AQVFEAGREGMKSLGMEGHQYLAAVHRD----TDNVHGHFMVNRVNPET---YKAVYP 137 Pseudomonas alc...
WP_007560590  65 RFEVSPSIEESAtFTD------ADWAELGNDFMQRMGLANHQYIIIRHSGteskKEQAHLHILANRVSLS----GELYRD 134 eubacteria
P06668        82 TTHIIVSFPAGTdQTAay---eASREWAAEMFGSGYGGGRYNYLTAYHVD----RDHPHLHVVVNRRELLGhgwLKISRR 154 Agrobacterium t...
Q9ZIP2        70 YRHHIQSFKPGE-VDE------ETAHKMAVEFAEKNFK-GFDVFISTHID----KGHIHNHIIINTVNIDT---GMKFRE 134 Fusobacterium n...
Q48665       111 GHHLIQSFSPDDnLTP------EQIHEIGRQTILEFTGGEYEFVIATHVD----REHIHNHIIFNSTNLYT---GKQFDW 177 Lactococcus lac...
Q54883        82 SHHIIQSFSPDDhLTP------EQINRIGYEAAKELTGGRFRFIVATHVD----KGHIHNHIILNSIDQNS---DKKFLW 148 Streptococcus p...
Q56424        57 VGHTSLNFSPED--GErlktddALMLQIAHDYMAKMGIENTQYIVARHTD----REHPHCHIVFNRVDND----GKTISD 126 Bacteroides fra...
Q4FIJ3       117 VFHYILSWQSHE--SPr----pEQIYDSVRHTLKSLGLADHQYVSAVHTD----TDNLHVHVAVNRVHPET---GYLNRL 183 Salmonella ente...
KFL47726      61 TYHLLVSFRAGE--KPd----aETLRAIEDRICAGLGFAEHQRVSAVHHD----TDNLHIHIAINKIHPTR---NTIHEP 127
Q00192        68 TYHLIVSFRAGE--QPs----aDTLRAIEERICVGLGYGEHQRISAVHND----TDNLHIHIAINKIHPTR---HTMHEP 134 Escherichia coli
Q9XAW2       138 D------------R--DYFKLDKTMREMELRQGWSHDKGpy---avHERNGQKVVDWAKDEpshrqpdreklpgkarqme 200 Pseudomonas alc...
WP_007560590 135 N------------W--IGKKATEAANAIAKERNFVQSQ-----------------DIGKVN------------------- 164 eubacteria
P06668       155 H------------PqlNYDGLRKKMAEISLRHGIVLDAT-------------SRAERGIAEr------------------ 191 Agrobacterium t...
Q9ZIP2       135 L------------NknEYNQKKENNVELKSHEFYLEDLKkssdeicLANNLSVIPQKEKAEsqniynr---------rey 193 Fusobacterium n...
Q48665       178 KvipkektksgkaYdvTKNNFEKVSDKIASRYGAKIIEK-------SPGN--SHLKYTKWQ------------------- 229 Lactococcus lac...
Q54883       149 D------------Yk-AEHNLRMVSDRLSKIAGAKIIEN-----------RYSHRQYEVYR------------------- 185 Streptococcus p...
Q56424       127 K------------N--DFYRNEKVCKMLTAKYRLHFANG-----------KDNIKEERLRP------------------- 162 Bacteroides fra...
Q4FIJ3       184 S------------W--SQEKLSRACRELELKHGFAPDNGcw---vhAPGNRIVRKTAVERDrqna--------------w 232 Salmonella ente...
KFL47726     128 Y------------R--AYRALADLCATLERDYGLERDNh-------ETRQRVSENRANDMErh----------------- 169
Q00192       135 Y------------Y--PHRALAELCTALERDYGLERDNh-------EPRKRGAEGRAADMErh----------------- 176 Escherichia coli
Q9XAW2       201 vmtGNESLTTYAQGQPKKDALEalnKGGGWHELHEALGRHGLEIR--QKGQGFAIHSKTDPEq-TPIKASTMAQE--LGG 275 Pseudomonas alc...
WP_007560590 165 -----KAEIKEAMDGVLKKMQG-----FDFTKFKEELGKRGFKVReaRASTGKLNGYYVTARsgTEYKASEIGKG--YTL 232 eubacteria
P06668       192 -----PITYAEHRRLERMQAQK-----IQFEDTDFDETSPEEDRR---DLSQSFDPFRSDPS--TGEPDRATRHD--KQP 254 Agrobacterium t...
Q9ZIP2       194 nvvMNKTSYKMELAKDIKRASKn---CKSKEDFIKALDEKGVIVDw-EDHKKHITFKFKDEKk-KSIRLANLEKT--FQD 266 Fusobacterium n...
Q48665       230 ----TQSIYKSQIKQRLDYLLE---MSSDIEDFKRKATALNLSFD---FSGKWTTYRLLDEPqmKNTRGRNLDKN--RPE 297 Lactococcus lac...
Q54883       186 -----KTNYKYEIKQRVYFLIE---NSKNFEDLKKKAKALHLKID---FRHKHVTYFMTDSNmkQVVRDSKLSRKqpYNE 254 Streptococcus p...
Q56424       163 -----YDKAKHEVYKALKGELP---HARSWNELKEALSERDIELKfkVSRTTKEVQGVKFEYggISFSGSKVSRE--FSY 232 Bacteroides fra...
Q4FIJ3       233 trgKKQTFREYIAQTAVAGLRSe--PVHDWLSLHRRLAEDGLYLS--QMDGKFLVMDGWDRNr-EGVQLDSFGPS--WCA 305 Salmonella ente...
KFL47726     170 --aGVESLVGWIKRECLPELQA----AQSWEDLHRVLRENGLKLR--ERGNGFIFEAGDG----TTVKASTVSRD--LSK 235
Q00192       177 --aGVESLVGWIKRECLDEIKG----AQSWQELHQVMRDNGMELR--VRANGLVFEAGDG----TMVKASTVARD--LSK 242 Escherichia coli
Q9XAW2       276 GKLTKRIGPY 285 Pseudomonas alcaligenes
WP_007560590 233 AHIERTQSKL 242 eubacteria
P06668       255 LEQHARFQES 264 Agrobacterium tumefaciens
Q9ZIP2       267 ETFKKEYLEQ 276 Fusobacterium nucleatum
Q48665       298 KYNLESIIER 307 Lactococcus lactis subsp. cremoris MG1363
Q54883       255 TYFEKKFVQR 264 Streptococcus pneumoniae
Q56424       233 MNIDYRLRRN 242 Bacteroides fragilis
Q4FIJ3       306 EKLMKKMGDY 315 Salmonella enterica
KFL47726     236 PKLEARFGAF 245
Q00192       243 PSLEARLGPF 252 Escherichia coli
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap