Conserved Protein Domain Family
Pellino

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pfam04710: Pellino 
Pellino
Pellino is involved in Toll-like signalling pathways, and associates with the kinase domain of the Pelle Ser/Thr kinase.
Statistics
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PSSM-Id: 461403
Aligned: 17 rows
Threshold Bit Score: 679.06
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_015784371       26 DSNYPIFYGELVILGYNGNLPHGEKGRRRSKFILTQRNVPNGVKKSKHYVVKQ-PQQTKAIQDKGKHSISYTLSRTQAVI 104
EKC24574          363 QNRSAIKYGELIILGYNGHLPSGDKGRKKSKFILGKKPSGNGVKPFRKHVVKN-AQAAKALQDPQSHSVTYTLSRHQAVV 441
XP_009008738       17 QTSNSVKYGELVILGYNGCLFNGDKGRRRSKFQLFKRQVPNGVKAAKHHIVNN-PQQSELIQNCHQHSVSYTLSRSQAVI 95 
FlyBase:CG5212-PB  21 HDKPRLRYGELVILGYNGYLPQGDRGRRRSKFVLHKRTEASGVKRSKHYIVQS-PQTSKAILDANQHSISYTLSRNQAVI 99 
KYB26669           61 KPKQLVKYGELVILGYNGFLPQGDRGRRRSKFVLYKRPTANGVKRSKHYVVKT-PHSSQAILDANQHSISYTLSRNHAVI 139
XP_011146164       59 KPKQLVKYGELVILGYNGYLPPGDRGRRRSKFVLYKRPVPNGVKRSKHYIVKT-PHSSQAILNTKQHSISYTLSRTQAVI 137
EEB13345            6 EEKKSIKYGELVILGYNGFLPPGDRGRRRSKFVLYKRLQPNGVKKSKHYVVKT-PHSSQAILDSKQHSISFTLSRNQAII 84 
XP_001625826        2 sSTEPLTYGMLVVLGYNGAPPQGNQERRKSSYLLQKKSLASGVKPFKQHLASS-QTGMQVVHSNQAHSVSYTLARGPSVV 80 
NP_001027714       43 EDEGDIIYGQLIVLGTNGQLPTGDKGRRRSCFTLRRKRKATGVKPSDQHQVYQkASHSETFLSKDHHSVSYTLPRS-VVV 121
XP_002589172       13 PEKAQLKYGELVVLGYNGSLPYGEKGRRKTRFTLFKRAAANGVKPSTHHIAKT-PQASKIVADKSHHSVSYTLSRNQTVV 91 
XP_015784371      105 VEYTPDNETDMFQIGRSSESPIDFVVIDTVSPDKPVG----DTLAQQSTISRFACRILVERNPPYTARIYAAGFDSSRNI 180
EKC24574          442 VEYKQDEDTDMFQIGRSSEPPIDFVVMDTIPGNLRSM----NEGITQSTISRFACRILVDRNPPYTARIYAAGFDSGKNI 517
XP_009008738       96 VEYDHDCNTDMFQIGRSSEEQIDFVVMDTIPGTQRGD----QSVIMQSTISRYACRILVDRTHPYAARIYAAGFDNGKNI 171
FlyBase:CG5212-PB 100 VEYKEDTETDMFQVGRSSESPIDFVVMDTLPGDKK------DAKVMQSTISRFACRILVNRCEPAKARIFAAGFDSSRNI 173
KYB26669          140 VEYTPDDDTDMFQIGRSSEAPIDFVVMDTVPGDKTG-----ETKVMQSTISRFACRILCDRKNPKIARIYAAGFDTSKNI 214
XP_011146164      138 VEYTEDEETDMFQIGRSSESPIDFVVMDTCAGGGDGGpa-nEGRVAQSTISRFACRILADRSDPRIARIYAAGFDSSRNI 216
EEB13345           85 VEYMPDEETDMFQIGRSSDPPIDFVIMDTIPGEKQG-----EERVNQSTISRFACRILADRSNPKICKIFAAGFDSSRNI 159
XP_001625826       81 VEYCRDNKTDMFQIGRSSDSKIDFVVMDTVPGVKDGAv---QPNPQKSTISRYACRITVDRHPPYTARVFAAGFDKSNNI 157
NP_001027714      122 VPYVHDDNSDMFQIGRSTEEPIDFVLMDIEAGSSIPTnhkpQTQPKQSTISRFACRIVCDREHPYTSRIYAAGFDTSMNI 201
XP_002589172       92 VEYVRDEDTDMFQIGRSTEPPIDFVVIDTVPGNKTAE----DCKVQQSTISRFACRIVVERNPTHTARIYAAGFDSSNNI 167
XP_015784371      181 FLGEKATKWQHD-GE---MDGLTTNGILIMHPKTTFCSngnviddipnsGQKYCLWREVSVCGGIYAIRETRSASEKGDK 256
EKC24574          518 FLGEKAVKWYVG-EE---IDGLTTNGVFIMKPQEGFYP-----------PGKPGVWREVSVGGAIYPLRESRSAPLKTNQ 582
XP_009008738      172 FLGEKATKWYTD-GE---IDGLTTNGILIMHPINGFTE-----------NSKTGLWRELSVEGGLYALRESRSAPNKGNL 236
FlyBase:CG5212-PB 174 FLGEKATKWQDN-VE---IDGLTTNGVLIMHPKGSFCGg----------NAKCGLWRECSVGGDVFSLRESRSAQQKGQP 239
KYB26669          215 FLGEKATKWQENgRE---IDGLTTNGVLIMHPRGTFCGg----------DAKCSYWLETSVGGGVFSLRESRSAQQKGQV 281
XP_011146164      217 FLGEKATKWQEN-RE---IDGLTTNGVLIMHPRGQFCGg----------EAQCGFWREVSVGGGVFSLRESRSAQQKGNV 282
EEB13345          160 FLGEKATKWQEG-RE---IDGLTTNGVLIMHPIGNFVDg----------DSKPGVWREVSVGGGVFSTRESRSAQQKGSV 225
XP_001625826      158 FLGEKAPKWKNEdDM---MDGLTTNGVLLMNPRGGP-------------NCPPGIWREISVCGHVYGLRDTRSAPEKGKT 221
NP_001027714      202 ILGEKAPKWTTEqNGkkiIDGLTTNGVLIMQPKNGFSE-----------SSTPTQWKETSVCGNIYQLRESRSAQLPGIR 270
XP_002589172      168 FLGERATKWKRPdSS---MDGLTTNGVLIMHPTGGFGQ-----------ECKAGVWREVSVCGGIYSLRETRPNPQRGKL 233
XP_015784371      257 IDLETNILKDGTLIDLCGATLIWRSAEGLLRSPTKKSLEDMIDDLNAARPQCPVGLNTLVISRKSSTL--CEk-EKQPYV 333
EKC24574          583 IKDEDNVLQDGTLIDLCGATLLWRSALGLISSPSEHEFENLVETINAGRPQCPVGLNTLVLPKKGTLG--LS--DRQPYV 658
XP_009008738      237 VSTENNVLKDGTLIDLCGATLVWRSNEGLVQGPTLVELEKQIEQINASRPQCPVGLNTLVLPCKNSMT--DN--EKAPYV 312
FlyBase:CG5212-PB 240 IYDECNILQDGTLIDLCGATLLWRSAEGLQHSPTKHDLEKLIDAINAGRPQCPVGLNTLVIPRKVNIG--DQ--VNQPYV 315
KYB26669          282 VENETNILEDGTLIDLCGATLLWRSAEGLTKSPSKRDLEREIDEINAGRPQCPVGLNTLVIPRKVTPN--EN--LQQPYV 357
XP_011146164      283 VEDENNILQDGTLIDLCGATLLWRSAEGLAKSPTKQDLEELVDAINAGRPQCPVGLNTLVIPRKAATD--ST--QQQPYV 358
EEB13345          226 IANETNILQDGTLIDLCGATLLWRSAEGLAKSPNRDYIEALVDKLNAGKPLCPVGLNTLVIPRKGTAD--SSneMEQPYV 303
XP_001625826      222 VQNESNVLFDGSLIDLCGAVLMWRSADAIPTMPTEGMIDAMRRRLNMMRLQCPVGLNTLVFSGASQVI--SLraSRQPHV 299
NP_001027714      271 MPEDNNVLVNGTLIDLCGATLLWRSSSHERCMPTPLHIDELIHKLNLGRPQCPVGLTTLAFPRRSKAT---KetEKQPWV 347
XP_002589172      234 IDDESNVLHDGTLIDLCGATLLWRSSAGLQKTPTHKHIEELRKEINAARPQCPVGLNTLAFPTRSRTTkvTEekERQPYV 313
XP_015784371      334 YLNCGHVQGLHDWGQSKNSNA----RTCPMCLSVGPVVRLTMGIESSFYVDCSSPT-FAFNPCGHMASERTVRFWSSIAI 408
EKC24574          659 YLQCGHVHGQHQWGQKDDKTA----RTCPLCLKDGTFIKLKMGCELSFYADSDPPT-HCFNPCGHMASEKTVRYWSELPV 733
XP_009008738      313 YLKCGHVHGQHSWGKGDDLNN----CTCPMCREVGPFVKLQLGEETSFYNDNGIIT-HCFSPCGHMASEKTVRYWSTVQI 387
FlyBase:CG5212-PB 316 YLNCGHVQGHHDWGQDENTGA----RRCPMCLELGPVVTLCMGLEPAFYVDVGAPT-YAFNPCGHMATEKTVKYWANVEI 390
KYB26669          358 YLNCGHVQGLHDWGQDKDSGA----RKCPICLELGPVVKVFMGLEPAFYVDSGPPT-FAFNPCGHMATEKTVKYWANVAI 432
XP_011146164      359 YLKCGHVQGHHDWGQEKDKVT----RRCPMCLVAGAVVKLSMGIEPAFYVDCGPPT-YAFSPCGHMATEKTVKYWEKVAI 433
EEB13345          304 YLNCGHVQGQHSWGQDKDSDA----RRCSLCFKVGPVVKVTMGIEPAFYVGIKSGNfYAFSPCGHMTTEKTAKFWSQTAI 379
XP_001625826      300 YIKCGHVHGLHGWHGPDSSTDvtesRTCPICLQVYNYVPLQIGKERAFFVGEIVSS-HAFVPCGHVCSEETVRFWSKIPI 378
NP_001027714      348 YLQCGHVHGRIEWGYQGEEE-----RICPLCRSVGKYVPLWVGGEPAFYVDIGPPS-YCFVPCGHVCSQKTAIYWSQTAL 421
XP_002589172      314 YLNCGHVHGHHLWGQKENENGd---RECPMCRTVGPYVPLYMGNEPAFYVDCGPPT-HAFCPCGHVCSEQTARYWAQVPL 389
XP_015784371      409 PHGTNGFHAMCPFCGTPVSGKLGFVRLIFQDHVD 442
EKC24574          734 PHGCQGFQAICPFCATPLCAETGFIKLIFQDNTD 767
XP_009008738      388 PHGCLGFQPACPFCATVLNELNPWVRLIFQDNMD 421
FlyBase:CG5212-PB 391 PHGTNGFQAVCPFCATPLDGATGYIKLIFQDNLD 424
KYB26669          433 PHGTNGFHAVCPFCASPLAGSPGYVRLIFQDNVD 466
XP_011146164      434 PHGTNGYIAICPFCAVPLEGTPGYVKLIFQDNVD 467
EEB13345          380 PHGTNGFDAVCPFCATPLTGYPGYIRLIFQDNVD 413
XP_001625826      379 PHGCDAFQAICPFCSLPLEGEDGFVKLIFSteq- 411
NP_001027714      422 PHGTQAYSAACPFCATPLEGDLGYKKLIFQQPLD 455
XP_002589172      390 PHGVHAFHAACPFCATQLTGEQGFIKLIFQN--D 421
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