Conserved Protein Domain Family
DUF1180

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pfam06679: DUF1180 
Protein of unknown function (DUF1180)
This family consists of several hypothetical mammalian proteins of around 190 residues in length. The function of this family is unknown.
Statistics
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PSSM-Id: 429067
Aligned: 11 rows
Threshold Bit Score: 114.602
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_001193113         10 LSRALASALLLs-----------LLLPElsgpsagrpPAARAAPDLQPAARGPRTR------------PPPPP------G 60 
Q8TBP5               10 LSHLLASVLLL------------LLLPElsgplavllQAAEAAPGLGPPDPRPRTL------------PPLPP------G 59  human
XP_003479489         10 LRNLLASALLL-------------LLPAlsrp-vavlRAAEASPGLGPLASGPRTL------------PPLSP------G 57 
Q5FVQ7               10 PCHFLASAFVL------------LLLPAlnqsvvlpsTVPRAVQESKPLEPGPRTL------------SPLPP------G 59  Norway rat
XP_851027            10 VSPLLAAALLLl-----------LLLPPpppg--pggAWASLLRAAAPGPAAPGTS------------PPLRP------G 58 
XP_016286766         12 CRRFLSAALLLalsgqlssllllLLLRDg--------AASDISRPLSPEASLPPSR------------PPLPPla--sgS 69 
WGS:AANI:GJ18424-PA   7 NWHLLALVLLLt-----------LFL-----------SHHDQSDAAAPNATSTNANtdprrtvkkdqaPPLPPaqdtavQ 64 
XP_006010435          9 SSCSLAWGLLIp-----------LLLS----------AAAGLSSTLPPAQKMDSSN------------RPSPP------- 48 
XP_015221295          9 FRASLFVCILLp-----------VLL------------------------------------------PPV--------- 26 
Q1RMK9                7 PARLLPLLLLL------------ALLGA---------PAARASRAQSAAPPQPGAErqp-------rpPPGPG------- 51  cattle
XP_003753342          6 PPPPLPLLLLLl-----------VLLAA---------PAVLARRAESASASQPEADhq---------sPPS--------- 47 
NP_001193113         61 SSAARP--AGRAPAlEAAGARGAEGGNGST------PGAGPAaddpggkagaggpAGGVLAVSP------------DPGD 120
Q8TBP5               60 PTPAQQ--PGRGLA-EAAGPRGSEGGNGSN------PVAGLEtddhgg-kagegsVGGGLAVSP------------NPGD 117 human
XP_003479489         58 PTAAQS--PGRAPA-ESPVLRGPEGGNGSS------PGAGLSaddlsg-kageasLGGSLAVSP------------NPGD 115
Q5FVQ7               60 PTAAQP--RGQAQS-EGAGPRGAESRNGSI------PGAASEadgpeg-kagessLGGSLAVSP------------NPSD 117 Norway rat
XP_851027            59 PTAAGS--PGRAPA-DAAGPRGAEGGNGSS------PRAGLAaddsggkareedsAGGSLAVSP------------NPGD 117
XP_016286766         70 ATAAGSglPGSSRT-EFPSGQAGLSGNGSS------PGAGPAe-----------vGGGGLSVSP------------SPRD 119
WGS:AANI:GJ18424-PA  65 QTSAESsvPEKVVViSEKSQQAAAQHEHPT------------------------------GVLPeedvhiehsnmnDNTD 114
XP_006010435         49 PVSG----PGNASTkPALHPNSNNHNNNNSnkpmndTRAGSG-------------GGGNLASVPgi---------pGSPE 102
XP_015221295         27 ATVG----PYKAPStKIQVGISQNTGNASSgntkmnTHTGSVgvregknnstgdfQSTSRTVAAel---------aANDS 93 
Q1RMK9               52 --------PGNATGtGSGEAAGGGGSSNSS----------------------------GDALVTri---------sSLLR 86  cattle
XP_003753342         48 --------PGNATQlGSG--MAGGGGSNSS----------------------------VDAVVTri---------sSLLR 80 
NP_001193113        121 KPMT-QRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEEDDNTLFDANHPRR 193
Q8TBP5              118 KPMT-QRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEDDDNTLFDANHPRR 190 human
XP_003479489        116 KPMT-QRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEEDDNTLFDANHPRR 188
Q5FVQ7              118 KPMT-QRALTVLVVVSAAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEDDDNTLFDANHPRR 190 Norway rat
XP_851027           118 KPMT-QRALTVLMVVSGAVLVYFVVRTVRMRRRNRKTRRYGVLDTNIENMELTPL-----EQD-DEDDDNTLFDANHPRR 190
XP_016286766        120 KPMT-QRALLVLMVVSAAVLVYFVIRTIRMRRRNRKTRRYGVLDTNLENMELTPL-----EQD-DDDDDTTLFDANHPRR 192
WGS:AANI:GJ18424-PA 115 FPDTyAAVFYILVGITSSAILVLVVRVYRL-RLSRAERKYGV-QGDRANQELTPLpmaieDVNsDEEEDHTLFEVN---R 189
XP_006010435        103 RPMT-QRALCVLVIVSAAVIVYFVIRTVRMRRKNRKTRRYGVLDTNIENMELTPL-----EQE-DDDDDNTLFDANHARR 175
XP_015221295         94 RPMSiQRALYVLVAVSALVIVYFVIRTVKM-KKNRKTRRYGVLDTNLA-MEMTPL-----EQDeDEDDDTTLFDARISRR 166
Q1RMK9               87 DLHTlKAAVIVACAFTAFLIACLLLRVFRSGKRLKKTRKYDIITTPAERVEMAPL-----NEEdDEDEDSTVFDIK---Y 158 cattle
XP_003753342         81 DLPTlKATVIVACAFSALLIACLLLRVFRLGKRLKKTRKYDIITTPAERVEMAPL-----NEDeDEDEESAVFDIR---Y 152
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