2PE4


Conserved Protein Domain Family
Glyco_hydro_56

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pfam01630: Glyco_hydro_56 (this model, PSSM-Id:396276 is obsolete and has been replaced by 460272)
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Hyaluronidase
Statistics
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PSSM-Id: 396276
Aligned: 121 rows
Threshold Bit Score: 361.055
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2PE4_A        10 NRPFTTVWNANTQWCLERHGVDVD-VS-VFDVVANPGQTF-RGPDMTIFYSSQlGTYPYYTPTG----Ep-VFGGLPQNA 81   human
XP_015836381  36 vQKVNYYWNVPTFQCD-SHKLNFTgLAdKFGIIQNENDRF-RGNEVAILYDP--GSFPALLRDGs--gIvrRNGGVPQEG 109  red flour beetle
OWR47683      35 KKEFRVYWNVPTFQCA-SKKIPFDkLYeKFGIIQNNGDRF-NGEKITILYEL--GDFPSIFKNKtsgeYefINNGVPQEG 110  Danaus plexipp...
XP_012544258  35 KKPFYVYWNVPTMQCR-SKKIPFEdLFeKFGILQNENDSF-LGKAVSILYDP--GLFPALLTNEtsgqIifRNGGVPQEG 110  domestic silkworm
XP_026300654  40 VREFNVYWNVPTFMCH-KYGLRFEeVSeKYGILQNWMDKF-RGEEIAILYDP--GMFPALLKDPng-nVvaRNGGVPQLG 114  honey bee
EFN78468      25 pHKFDVYWNVPTFMCH-KYGMKFEnLN-DYGIQQNAMDKF-RGDKIVILYDP--GMFPALLVSKng-tVtkRNGGVPQEG 98   Jerdon's jumpi...
EEB14203      24 lEEFKIYWNVPTFLCH-KYGINFKpHTeKYGITSNPKDSF-RGKEINILYDP--GMFPAVMKNAkg-vVaeRNGGIPQLG 98   human body louse
EEB14205     221 HRGFKIYWNVPSDRCK-KHNIHFEpLTkMYGIIANKNDSF-RGENVSILYDP--GEFPIIQKFPnn-tVkyHNGGFPQNG 295  human body louse
EEB14204      37 NRGFKVFWNVPTEQCK-KYEIDFEsLIrTYGIIGNERDSF-RGEKVTILYDP--GDFPIIKKFQnk-tQryYNGGFPQNG 111  human body louse
XP_011678102  64 QSVFRAIWDVPNF-CKDRYSIDIP-LG-AYGIEFNQNHEWrVGDVLNVFNHQS-GCFPYVNRTT----GifMNGGLPQLG 135  purple sea urchin
2PE4_A        82 SLIAHLARTFQDIlAAIPaPDFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRAL--VQAQHPDWPAPQVEAVAQDQFQGA 159  human
XP_015836381 110 NLTLHLALFEELLnELLP-EDFSGLGIIDFESWRPIYRQNFGSLAPYKDLSVEI--ERQSHPFWPKLLLEKEARRRFEFH 186  red flour beetle
OWR47683     111 NLQEHLVAFKEQLlEKIPdPFFDGVGVIDFEMWRPVFDQNFGNLDVYRKRSIEI--EKERHSWWLNMWIKKEAAIRFETA 188  Danaus plexipp...
XP_012544258 111 DLAKHLEVFRRNLvQCVPdEDFSGVGIIDFESWRPIFRQNFGALVPYKDVSYEI--EKKLHWWWPKQWVQTEAIQRFEES 188  domestic silkworm
XP_026300654 115 NLTKHLQVFRDHLiNQIPdKSFPGVGVIDFESWRPIFRQNWASLQPYKKLSVEV--VRREHPFWDDQRVEQEAKRRFEKY 192  honey bee
EFN78468      99 DLKEHLEKFREDLvTQIPhESFSGVAVIDFESWRPIFRQNWASLEPYKTLSIKL--ERERHPFWSDAAVKKEAKRRFEKF 176  Jerdon's jumpi...
EEB14203      99 NITLHLEAFKNVV-EQIVsPDLHGIGIIDFETWRPVFRQNWRDQVVYKNLSKDL--ERQYHPQWSEKKIREKAKIHFEEA 175  human body louse
EEB14205     296 SLEKHLEKLKADI-EKFVyKNFSGLGIIDFEVWRPVFRQNWNDQVIYRNKSFEWakELKNNCSIAEGKINATAKETFEAH 374  human body louse
EEB14204     112 SLSKHLKKLKNDT-RKYAnVNLNGLGIIDFEVWRPVFRQNWNEQIIYKNKSIELaqHLKNNGSLNGKSVNASAKEEFEKH 190  human body louse
XP_011678102 136 NITAHLEKMADDInREIPdRQYNGLVMIDWEEWSPQW---LGTEPRYRRFSMDS--VRSKHPGWDNATIEAVAKLEWTQG 210  purple sea urchin
2PE4_A       160 ARAWMAGTLQLGRALRPRGLWGFYGFPDCYN-YDFLSPnYTGQ---CPSGIRAQNDQLGWLWGQSRALYPSIYMP-AVLE 234  human
XP_015836381 187 ARRFMEETLFVAKSLRKNATWGYYAYPYCFNmSPNNMKk------dCPNEVQKENDQLDWLFRLSDDLHPSIYLD-GRLG 259  red flour beetle
OWR47683     189 ARKFMESTLVLAKQMRPNALWGYYGYPHCFNmRDMDMKe------dCVKSIPGANDNIYWLWAESTALFPSIYSS-KKLT 261  Danaus plexipp...
XP_012544258 189 ARTFMQRTLLVAKEMRPNAQWGYYGFPYCFNmASNNMKe------sCAEKVPEENDRLHWLWSESTALYPSIYSS-RDLT 261  domestic silkworm
XP_026300654 193 GQLFMEETLKAAKRMRPAANWGYYAYPYCYNlTPNQPSa------qCEATTMQENDKMSWLFESEDVLLPSVYLR-WNLT 265  honey bee
EFN78468     177 GRMFMEESLKMAKKLRPWAMWGYYGYPHCFNkSPGQQSm------hCDRSTMTENDEMSWLFMLEDVHAPSVYLR-LEIK 249  Jerdon's jumpi...
EEB14203     176 SKEFMEKTLELAKILRPKAIWGYYGFPYCYNyRTTDEPe-------CPELARRENDKILWLFNTSTAFYPSLYMS-TKLN 247  human body louse
EEB14205     375 AKKFMLETLKEVKKLRPEGKWGYYGFPYCYNyRVNDTPe-------CPKIAVKENNETLWLFNESTALYPSIYIK-TKYN 446  human body louse
EEB14204     191 AKKFMLETLEDVKKLRPGGKWGYYGFPYCYNyRVNNTPe-------CPEIAVRENNEILWLFNESSALYPSLYLK-QSYN 262  human body louse
XP_011678102 211 AKLFMESTLKLFKQLRPESLWGYYRYPQCAV--------KFGRipeCQPDQGKLNDQSLWLVDASSILYPSIYLKpEKFA 282  purple sea urchin
2PE4_A       235 GTG-KSQMYVQHRVAEAFRVAV---AAGDP--NLP-VLPYVQIFYDtT--NHFLPLDELEHSLGESAAQGAAGVVLWVSW 305  human
XP_015836381 260 PK--DKIRMIEGRINEAHRVAA---FVKSGalKPK-IVPYFWYKYH-Gg-qNFLTKEDLFNAILTLSTSDIDGVVIWGSS 331  red flour beetle
OWR47683     262 NS--QLPFHIKGRIKESARVRLe---------DTP-ILPYFWFRYR-Da--EFFSQEDLSIALNTLYQSKASGVIIWGSS 326  Danaus plexipp...
XP_012544258 262 SS--QLSRMIRGRIKEAQRLNRn---------DAP-VLPYFWFRYR-Dg--GYMTEEDLNSALQAIYASNASGFIVWGSS 326  domestic silkworm
XP_026300654 266 SG--ERVGLVGGRVKEALRIA-----RQMTtsRKK-VLPYYWYKYQ-DrrDTDLSRADLEATLRKITDLGADGFIIWGSS 336  honey bee
EFN78468     250 EG--DRPGFVKGRVSEAQRLA------VKSlrKQQ-ILPYYWFKYQ-DnrDKLLSEKDTMNTIEMIANHGADGAIIWGSS 319  Jerdon's jumpi...
EEB14203     248 EF--QQSQFVIGRLNEAWRMA-----IKVSgpKIPrVNPYIWFKYY-Ds-eEFLSYADIYSALDVTRKYKMGGAIIWGSS 318  human body louse
EEB14205     447 ET--EHVKFMIGKLNEAYRVS-----AMAN--YVP-VYPYVWFRYL-Dn-dTYLTEADMFYSIDIPRHYQMGGIILWGKG 514  human body louse
EEB14204     263 SS--EHVKFMIGVLNEAYRIS-----AMTN--YIP-VYPYVRFKYL-Dt-dEYLTQEDAYNSFEIPRQYQMGGIILWGKS 330  human body louse
XP_011678102 283 DFAgA----VGAKLEETFRVLTeskYPDGA------VMSYTRFNY--SltDYYFTLEDLNNTILTSAEFGTHGVVLWGDN 350  purple sea urchin
2PE4_A       306 ENTRTKESCQAIKEYMDTTLGPFILNV 332  human
XP_015836381 332 NDVNTKNKCLDLYEYVDNVLGPSLVNf 358  red flour beetle
OWR47683     327 NDVNTVDKCKKLYNYVETILGPNIAKY 353  Danaus plexippus plexippus
XP_012544258 327 NDVNTVKKCHNLREYLEGTLGPAIAKY 353  domestic silkworm
XP_026300654 337 DDINTKAKCLQFREYLNNELGPAVKRI 363  honey bee
EFN78468     320 NDVNTQRKCEDLLQYMKDVLGPTkeel 346  Jerdon's jumping ant
EEB14203     319 NNVNSKEKCKTLLRYLDTVLGPAArkt 345  human body louse
EEB14205     515 SDLDSKDKCQKFFQYMNETLGPALnrs 541  human body louse
EEB14204     331 SDLNDEGKCLKFYNYVIDIVGPALnks 357  human body louse
XP_011678102 351 YDDKTSQSCQELRDYVIKALGPTVVMA 377  purple sea urchin
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