Conserved Protein Domain Family
HAD_like

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cl21460: HAD_like Superfamily 
Haloacid Dehalogenase-like Hydrolases
The haloacid dehalogenase (HAD) superfamily includes carbon and phosphorus hydrolases such as 2-haloalkonoate dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, among others. These proteins catalyze nucleophilic substitution reactions at phosphorus or carbon centers, using a conserved Asp carboxylate in covalent catalysis. All members possess a conserve alpha/beta core domain, and many also possess a small cap domain, with varying folds and functions.
Links
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Taxonomy: root
PubMed: 575 links
Book:22 links
Protein: Related Protein
Related Structure
Statistics
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Accession: cl21460
PSSM Id: 473868
Name: HAD_like
Created: 5-Sep-2014
Updated: 4-Oct-2023
Superfamily
Curated CD Hierarchy
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