Conserved Protein Domain Family
COG5594
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COG5594: COG5594 
Uncharacterized integral membrane protein [Function unknown]
Links
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Statistics
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PSSM-Id: 227881
Aligned: 8 rows
Threshold Bit Score: 770.819
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6324488    1 MADSSS-------------------------TSAFISTLIIYGLTAVVFVWLFLLLRPKNRRVYEP-RSLKDIQTipeEE 54   baker's yeast
19074467   1 MDDMDKdnivngae----------kpplsraDNAVLTNAVFQGFITFCILIAYVILRKRAKWLYSP---NVRGRP----S 63   Encephalitozoon cu...
1175441    1 MSDSSSs-----------------------sTSAFVSSLVFNFAIFCAFIGLFLCLRPREKHVYQP-RCIIDTQp--kEE 54   fission yeast
1175480    1 MVFSTVilekird-----------sslktdpSSDLRTQFWLAFLLGASACVFFCFFRKRWKVLYAP-RTTIEGLN----- 63   fission yeast
19112024   1 MVIEKResfiev--------------vinslLNDNPAQAKFDKYSILVSLGFSSLLSVILLCIFTLlRTKFNTYD---RC 63   fission yeast
6323024    1 MNATKEltfnllnkfqdkerfgsaqrhagisLKGFISGILFSFLYFLFQLSLFIILRSRFKTIYQA-NVVLKIHPgskVC 79   baker's yeast
6323270    1 MTSYIErlksaasyldtv--pdehhdfrkptAKVVTTQLTIATSLGIFALLSFSILLKKWPRLYAS-RRYKDDGN---LR 74   baker's yeast
2497214    1 MNSTNStnsttta------------tstntsTQQVVTSLVSNGTIFGVFVIAFLILRIKLKRIYEP-KSSFNLINe--EK 65   baker's yeast

6324488   55 RTEPVPEGYFGWVEYLLSKP-------HSF-LIQHTSVDGYFLLRYIGIVGSLSFVGCLLLLPILLPVN--------ATN 118  baker's yeast
19074467  64 HPCYNYTGFLSWIIPVVTVN-------DTI-LLSIIGLDAFMMLQTLKMLYRILFILSLFVIPSLGYLFwtn---qrENV 132  Encephalitozoon cu...
1175441   55 KPEPSPSSPFGLFAYVVKRS-------ETY-LIQYAGVDGYFFIRYLFTFGALCILGCLVLFPILLPVN--------ATN 118  fission yeast
1175480   64 LP-TLSSSYYKWLMDLVNIP-------DDV-VQNCAGLDGYVFLLFFKMGIKFLSFASLLGVLIIMPVNkhf---rgDAF 131  fission yeast
19112024  64 IP-PMKKSLWGWIEPLWSIK-------VED-CLYNMGADAVISLLFSRFCRDVFLILAAICCTILIPINiva---tnKTL 131  fission yeast
6323024   80 FAKKKIKNYWSLFAFLKQLPgrmldpmEKFeRNERYGLDNYLFLRFLKLLIFFFAVLSIINIPILIPIHyfsrdilkENE 159  baker's yeast
6323270   75 LPSWNQSSLFGWLTVLYKIR-------DEQ-ILEYAGLDAYVFLSFFKMCIKLLSIFCFFSVCVISPVRyhf--tgkIDD 144  baker's yeast
2497214   66 KPEPLPQGVWQWLKPLLKKS-------DNF-VIQQAGLDGYFFLRYLFIIAIYCAVSMSYIFPILLSIN--------ASN 129  baker's yeast

6324488  119 GN------------------NLQGFELLSFSNVTN--KNRFYAHVFL---------------SWIFFGLFTYVIYKELYY 163  baker's yeast
19074467 133 EH------------------SDQWLVRLSLGSLDP--DSGSYRLVIPv--------------VYLISGFIMYSIFIYYKR 178  Encephalitozoon cu...
1175441  119 GV------------------GEKGFDILSFSNVKN--HNRFYAHVFL---------------SWLFFGFTIFIIYRELRY 163  fission yeast
1175480  132 GNitlsmpakseyffssplvKKSIVQSPIIANGSElnVGVLGPSLFNpignlsdipglpqpgDGFLYLYVLFTYFISIFL 211  fission yeast
19112024 132 ANs----------------dSQNAYAKLSIQNVTG---NWTWAHVVI---------------CYVFNVLVLFLLARYYQI 177  fission yeast
6323024  160 GEryeq-----------sfrTTSKLDKWTMSNLSPnsSNTLICHLFL---------------SIFVVLWFHFILSSELRF 213  baker's yeast
6323270  145 GNdd--------------ddSESSLIHLVKRIVEG--SGDGDNHSAPer------------tNVYLWMYVLFTYFFTFIA 196  baker's yeast
2497214  130 GN------------------HESGLNQLAYQNVKH--RGRYFAHVFC---------------GWIFFWGFLYIIYRELYF 174  baker's yeast

6324488  164 YVVFRHAMQTTPLYDGLL----------------------SSRTVIVTELHKSIAQEGE-MQMRFPKASNVAFAYD---- 216  baker's yeast
19074467 179 YIVLRQAYLRNPAIMTSIitlkklsnhlgssersteyvnlPNRTLLVSRLPSYVNNDVD-LYEFINALGVGEIDDSvlv- 256  Encephalitozoon cu...
1175441  164 YVIFRHAMQSSGLYNNLP----------------------SSSTMLLTELPNSVLNDEEtLHELFPNASEFTCVRD---- 217  fission yeast
1175480  212 LYVLFSSTKSIADIRQSYlarq---------------nrlTDRTVFISGLPNELCSTEN-LKAYFDKLDVGSIDSLsic- 274  fission yeast
19112024 178 VMRIRQRYYRSPTYQQSM----------------------SSRSLLIMDIPTTMRSNNG-LSILASRLKSSEAPMH---- 230  fission yeast
6323024  214 VNRLGYSVLTKSKYQNILylegfss---------klvtqsISLETFFQPLHSDCFGVTHfIPKNLKKVHKLEIKLNklqk 284  baker's yeast
6323270  197 IKMAVAETKHVVSTRQAYlgkq---------------ntiTDRTIRLSGIPIELRDSEA-LKTRIEQLKIGTVSSItic- 259  baker's yeast
2497214  175 YTSMKQAVLASPRYAKKL----------------------SSRTVLFQTVPKQYLSEEE-FSKLFDGVKRVWIARG---- 227  baker's yeast

6324488  217 ------LSDLQELCKERAKNAAKYEAALNKVLNKCVKMT--------------------RNKTQKQLDKLYNNGT----- 265  baker's yeast
19074467 257 ----ydTNTLQSLYGERDSYIYNIEKEINEKFVRINDWSeknreacersisgfkesisrTVEEAKIEGTFDPSQKrqliv 332  Encephalitozoon cu...
1175441  218 ------LKKLEKKVKKRSDLGNKYESTLNSLINKSVKK---------------------HNKLVKKHKPLPST------- 263  fission yeast
1175480  275 ----rnYSYMDILLSKKSKYVKKLEKYWSIYLSNCKKL---------------------GISTLPPSNYLSPNR------ 323  fission yeast
19112024 231 -------VHICHAIKNLPKILKKHDNAVRSLEAVLAKF-------------------------FKNPKKLPDD------- 271  fission yeast
6323024  285 skeqiiFEIILEKYFRRVSIHRHLIANHKRFFFSKLKNH--------------------LLFQYKKLVFLTQFRIsyyct 344  baker's yeast
6323270  260 ----reWGPLNKLFHCRKKILKNLELKYSECPRELRTRQpys--------------enyHLLGNEQSGAVTHGENvpss- 320  baker's yeast
2497214  228 ------SGSIEAMVKARDNMAIQLEGAETKYLKAALKK---------------------IKKLNKKSPQLSVS------- 273  baker's yeast

6324488  266 ------KPKDDLETYVPHKKRPKHRLGKLPL---------------CLGGKKVNTLSYSSKRIGELN------------- 311  baker's yeast
19074467 333 lflngaKQFENKLKEGEDVSRVSLYLEKLNDvnarisrekeiikteEAGDKDVRIVELVSRNNTLFLrgdisqdvsffsf 412  Encephalitozoon cu...
1175441  264 ---------LDYTAYV--KKRPTHRLK-------------------FLIGKKVDTIDYCRDTIAELD------------- 300  fission yeast
1175480  324 ------AELESTPEQLLEVPWQHHQCHPLIKth-----------ffGIFGQKIDAIDFYSAKLYKIS------------- 373  fission yeast
19112024 272 --------------------RPVRRVKQG-----------------LLTSEKVDAIDYYSAKIENYG------------- 301  fission yeast
6323024  345 kirlrwKKSSIFPLYYPKLYVNTETILERKY---------------RILDKIIRKEKLIKFQVNSLK------------- 396  baker's yeast
6323270  321 ---nnnDEDTILYSQISLGERPKMKIGYR-----------------GIFGKEVDAIEYLEQQLKFID------------- 367  baker's yeast
2497214  274 ---------DNIAEYVPDKKRPHHKINKVAK---------------FFFGKKVDTISYIKEELPKLN------------- 316  baker's yeast

6324488  312 EEIHEKQADWASNDR-----QPACFIQFETQLEAQRCYQS--VEAILGKKnfgKRLIGYSPEDVNWGSMRLSS-KERHSR 383  baker's yeast
19074467 413 HHILNYRKYKMYFTLdlpskTKRGFVTFKDQRSANIVKQSqiGSRIFSVT----TEDAPAPNDVIWENITNSE-VENYMY 487  Encephalitozoon cu...
1175441  301 EVVDKLQTSLEERKK-----VGSVFIRFRSQTDLQTAYQAflYSKKFRKYrfgRALVGIAPEDIVWSNLDLSM-YTRRGK 374  fission yeast
1175480  374 QQIENARSFDYPTTG-------QAFITFESMATAQIVAQThiDSKSLMGL---HIELAPAANDIQWHNTYIGR-WHKFFQ 442  fission yeast
19112024 302 LRVDAARESLYENEF-----EHYGFITYKSSYIAHDTARHn--SRVAGAS----VSMAPEPSDFLWDNLSLAW-STRLFN 369  fission yeast
6323024  397 ATSETKQALPDDLSSgtdiyMDKMFITFKSTLLSNVIGELlsYRLPTQNL---KVIIGPNVNDIIWRNILDSSpLWKSAK 473  baker's yeast
6323270  368 AEIIEARKQHYSATP-------TAFVTMDSVANAQMAAQAvlDPRVHYFI----TRLAPAPHDIKWDHVCLSR-KDRLTK 435  baker's yeast
2497214  317 QKVKALQEDHENSSP-----FNSVFVEFESQYQAQVAAQIttYHAPLFMT---PVYIGIEPSDVVWFNLRMFW-WERLGR 387  baker's yeast

6324488  384 RAVANTIMVLLIIFWAFPVAVVGIIS-NVNFLTDKVPFLRFINNMPTFLMGVITGLLPTIALVVLMSLVPPFIVMLGKLS 462  baker's yeast
19074467 488 SIFGTVFFILFIVLFSSMVTSIVTLLvNFEGFKESK-LISSFLSRYETIADSLRGALSPLIYNSMLLLVPTVITALMNME 566  Encephalitozoon cu...
1175441  375 KTISNTILTLMIIFWAFPVAVVGCIS-NVNYLIEKVHFLKFIDHMPPKLLGIITGILPSVALSILMSLVPPFIKFLGKFG 453  fission yeast
1175480  443 GWFITLVTFMIILLWTVPVGAIAVFI-NLDTIRRLWPELGRMIEDLPFLNSLLRTFLPTLVYSLFISISPFLFRWLSSMQ 521  fission yeast
19112024 370 RMIGNILFIILIIAWIIETALVAIFIsNLYHLGSVWPWLQQQLTSRSGFWSIVQGILSPAVAGFTFMILEIIMRRISYWQ 449  fission yeast
6323024  474 YFSANILRIFVIIGWILPVAFLGLIS-QIPNISSLIPFTKIIHFQSPFIREVAKNLIPIVTLIIIIEIVPYFFRWLSYLR 552  baker's yeast
6323270  436 VYSTTVFIGLSSLFLVIPVSYLATLL-NLKTLSKFWPSVGQLLKDHQWAANIVTGLLPTYLFTLLNFGIPYFYEYLTSYQ 514  baker's yeast
2497214  388 EVSAVSAIVALVILWAFPVAFVGMIS-NITSLTNEVKWLKFIYKLPKQLLGLLTSLAPTVALAVLMSFLPKFIRGMAITQ 466  baker's yeast

6324488  463 GCVTRQETDLYSQAWYYAFAVIQIFLVVTATSSA----SSTVDSIIDR-----------PRSAMTLLANNLPKASNFYIM 527  baker's yeast
19074467 567 GIYSYSTLQQKLMDKLCNFLFFNGFASVFFVTSFyr-lFSDVLSRNKE-----------IYDIVEAFSKESLESSVFFAN 634  Encephalitozoon cu...
1175441  454 GALTVQEIENYCQNWYYAFQVVQVFLVTTMTSAA----TSAVVQVIKE-----------PASSMTLLASNLPKASNFYIS 518  fission yeast
1175480  522 GLSSRAEEEIYAVGKNYAYLFVNFFLVYVIAG------STSIWELAKD-----------TTSFAHFLANRLPHQAQFFID 584  fission yeast
19112024 450 GSFTKSSRERGVLNKLHIIFTLDNFIIYTLMAVFwrlgVIIAYKTKEEgnfaegmsafaTFDTVGLSVSSFVQFSTFWIM 529  fission yeast
6323024  553 GLKTGAQIEADVQNWYFVFVFIHLFVVVTISSGF----SIIIERLLNN-----------PVSIPALLANDLPKCANFFCS 617  baker's yeast
6323270  515 GLVSYSEEEISLVSKNFFYIFVNLFLVFTLAG-T----ASNYWAYLSD-----------TTKIAYQLATSVKEFSLFYVD 578  baker's yeast
2497214  467 GAPSKQNVEYFTQQAYFAFQVIQVFLVTTLSSAA----TSTVTEIVKE-----------PTKAMDLLASNLPKASNFFMS 531  baker's yeast

6324488  528 YFILKGLTGPTWTILQAVNLLLSKVLGRVLDSTPRQKWNRYNTLATPRMGIVYPGIEILVCIYICYSIIAPILLFFSTVM 607  baker's yeast
19074467 635 IIIQKSLVGTALTLLKPAPLLINYIIFPFTGRKTRREKLDAEFSPPFDFGTIFPSCLTVFSMSIAYAVMCPPILLLGAFF 714  Encephalitozoon cu...
1175441  519 YFLLQGLSIPGGALLQIVTLLLSKVLGRIFDNTPRKKWNRWNQLSAPSWGTVYPVYSLLVTIMICYSIIAPIIIGFAAVA 598  fission yeast
1175480  585 LIVLQGIGMFPLKLIQLGKLSSYFVRRSFVPYSIAS--KKFETPDSFSVGIFLPQPMFIMLICLCYSIISPLILVFGLIY 662  fission yeast
19112024 530 FIAHSTCSFF-VEIAQPITLTIRLIKTKFFSPTPRD-LLEWTAPTKYVYSQVLNKLIYFFTIAICYACINPLVLLFASVL 607  fission yeast
6323024  618 FVLIRGMAYAGGNLLRIKELLFELFYYKWKRSTPHAQFKRLKTSLFFQLGSIYPIFSVLGCIGIIYSVVAPIILLLCCIS 697  baker's yeast
6323270  579 LIILQGIGMFPFKLLLVGSLIG-FPLVKIKAKTPRQR-NELYNPPIFNFGLQLPQPILILIITLIYSVMSTKILTSGLAY 656  baker's yeast
2497214  532 YVILQGLSISSGALLQIVPLILFYVLGAFLDGTVRKKWNRFCGLSSMQWGTAFPVYTNLAVITFSYSIISPLILLFAAVA 611  baker's yeast

6324488  608 LTLLYVAYLYNLNYVFGFS--FDLKGRNYPRALFQIFVGIYLSEVCLLG-LFIMAKTWGPLVLEVFWIVVTALAHIYMKR 684  baker's yeast
19074467 715 YFCNYLAFKSEFLYSSRNE--YESGGGYWDSACQNIVFSLIFFQVVTFA-KMSSDKRFYLSMSLFPIILITFIFRNSLRK 791  Encephalitozoon cu...
1175441  599 FVLIYFAYSYNLIYVLGHN--ADAKGRNYPRALFQVFVGLYLAEVCLIG-LFVLAKNWGATVLEAVFLGFTVACHLYFKY 675  fission yeast
1175480  663 FIIGFLVYKYELIYQMEHP--QHSTGELWSTIFLRMIFGCVIMQLTMMG-LMSLRKAYWLSTVIFPLLCFTVISAYNFST 739  fission yeast
19112024 608 FCVNYLTQKYILMYVSNSS--TESGGGYWRPVVNRILLGLELANIILFL-CLWVQGGRVRAYCIIPNFSFAIAFKIWCMF 684  fission yeast
6323024  698 FSMVFFSFSYLFKYQYNKEnySETFGKLYIQALMQLYAGIYFMEFCLLG-LFTLFDQYTLSTIMLVVFALTVITHS--KI 774  baker's yeast
6323270  657 FIIGFYVYKYQLIFATDHL--PHSTGKVWPLIFRRIIVGLLLFQLTMTGtLAGFEGGWVLSSCLFPLPVVTLCFLYDFEK 734  baker's yeast
2497214  612 FFLLYIAYLYNLTYVYQES--PDARGIYYPRALFQTIVGIYIGQICLLG-LFAVGKGWGPIVLQVIGICVTVLIHLHLSA 688  baker's yeast

6324488  685 KFIPL-FdavplSAIRh---ARGepgysYptsdlglqeiKdiademkgkyeqdnthgiltpvtkddlkkaNLIPdndgss 760  baker's yeast
19074467 792 MFY---------KSCH----FYP-----------------------------------------------LNIK------ 805  Encephalitozoon cu...
1175441  676 KFLPL-MdavpiSAIEs---VSErpeikYpmdlg-tsemKnv---------------------------gRAYPeilekl 723  fission yeast
1175480  740 MIR---------SSMQ----FVS-----L-----------------------------------------YYIR------ 754  fission yeast
19112024 685 ALDPKsHymiedPYMKvvepLENeisesEmcfghpstyaP------------------------------LLVPmvrsd- 733  fission yeast
6323024  775 S-----------KQIK-----SK----------------P------------------------------QRIP------ 786  baker's yeast
6323270  735 NYLPL-S-----KYIA----LSS-------------------------------------------------IR------ 749  baker's yeast
2497214  689 AFDHL-SkvipvDTMKpldgVSDtpsfkNiykgiestkvKkntfgan-----------------idmdgiKELPefpikk 750  baker's yeast

6324488  761 engtpsnpfesgseraslsgsnaesdsikklndtVIKKSSTLSSSTKdnnestfvpegekfrkfhysdvealrnkrpYDE 840  baker's yeast
19074467 806 ----------------------------------EEEYLDTFTEKVL------------------------------VDR 821  Encephalitozoon cu...
1175441  724 s--------------------------sssgsdeFLETSSRTSENTKe----------------------------kIDK 749  fission yeast
1175480  755 ----------------------------------THQSNTLSSESESr-------------------------------- 768  fission yeast
19112024 734 ------------------------------aralLPLFYSGRTETHNkfd-------------------------faTDS 758  fission yeast
6323024  787 ----------------------------------TLEYLSNLTEERK--------------------------------- 799  baker's yeast
6323270  750 ----------------------------------EYERDNSTVNSAN--------------------------------- 762  baker's yeast
2497214  751 yh------------------------krsesvteQQVENSIFSENTFeyq------------------------fnpANE 782  baker's yeast

6324488  841 DDhskhgpegavpvnadagviysDpaavmkepqafppdvletntwtrrilqffnprrsypFDSVRMRFPLVFNTSIEYde 920  baker's yeast
19074467 822 VN----------------------------------------------------------LLESWSEIGKGPDVDILR-- 841  Encephalitozoon cu...
1175441  750 DDegf---------------aitNissvhkmpsfvlsy---------fsdlaasnriltgFDRVLQLLPSFYDIPVRvrn 805  fission yeast
1175480  769 -N----------------------------------------------------------SESSGSYVHPGFDLSNE--- 786  fission yeast
19112024 759 DDas------------------eKhlrg----------------------------eeepLENVDFVDIDNVDTAKEVhd 792  fission yeast
6323024  800 -D---------------------Q------------------------------------FCQESYTFHDIFSICRN--- 818  baker's yeast
6323270  763 -E-----------------------------------------------------------EESYAYPYAVSELEGP--- 779  baker's yeast
2497214  783 ANadgh--------------ainAenliedvplladgdtmki-ppapwwkrflkphiyysYKAVKSRLPEIYGLVDPDer 847  baker's yeast

6324488  921 eyl------ssayTDPCVREKDPIVWCCKDPLGVSKQQIQEARSNGLDVRDDFTRYDEKGKVIFTYNPPDY 985  baker's yeast
19074467 842 --------------LAELGIKDTKEIEKESYYNDPNTATSNSSLILPENFFKTIWFLVNNDREDLFGLRAE 898  Encephalitozoon cuniculi
1175441  806 ----------vqyVSPALKATPPSVWIPKDPLGLSTYAIEDARG-KVDIFDDNTTFNEKGNLQYTGPPPDY 865  fission yeast
1175480  787 ------------------------ELPLID-LNTA------------------------------------ 796  fission yeast
19112024 793 qqqvqqlkknlsrSYTRSRGVSLRARLNEEELPLTESITQDSQISIPETLESQSTEITPINVSEHYDKYYH 863  fission yeast
6323024  819 -------------SD--------EIWLPRDKLGISEEEQSFLEKSYHLKFDLNMYSMNLFGDCHLENSHLH 868  baker's yeast
6323270  780 ---------------------------MLD----------------------------------------- 782  baker's yeast
2497214  848 vndf---dishayDYPAVSAQCPELWIPRDPFGFSKLLISDVSG-VVEMNDENATIDENLKFTLRDVPPPY 914  baker's yeast
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