Conserved Protein Domain Family
ODR4-like

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pfam14778: ODR4-like (this model, PSSM-Id:405468 is obsolete and has been replaced by 464311)
Olfactory receptor 4-like
In C.elegans, odr-4 and odr-8 are required for localising a subset of odorant GPCRs to the cilia of olfactory neurons. Olfactory receptors (ORs) are synthesized in endoplasmic reticulum of the olfactory neurons, trafficked to the cell surface membrane and transported to the tip of the olfactory cilium, where they bind with odorants. Various accessory proteins are required for proper targetting of different ORs to the cell membrane. ODR-4 was the first accessory protein to be described.
Statistics
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PSSM-Id: 405468
Aligned: 53 rows
Threshold Bit Score: 224.925
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEH51996      30 GLLLGK-LeVG-SRDVVLALVPTPAkeeddddaGGGPGPGRdaSSSsa------------aaASasalEIDEDWIVEHAT 95  Micromonas pusi...
KJE97509      27 GLLIGQ-MtAG-QRDHIVAIVPTPKdetasattATTTATEQgaGASkkaaagktpassnatsMQaqieGIDQEWVVAHAR 104 Capsaspora owcz...
XP_003288942  25 GLLIGQqSnIN-DEAYVLGFFPSPPqlseysdtNTEKKQEQqeKIT----------------TNdlkkLIDKEWILEFCF 87  Dictyostelium p...
Q54QH3        26 GLLIGQeSeISeQQTFVLGLFPTPLnisntdddNNNKPINIdsISS-----------------------IDKEWILEYCH 82  Dictyostelium d...
XP_004355872  30 GLIIGQ-------NQVFIGSVPTPPlygddnqiTKYKTIK----------------------------DFDQIWISEHAR 74  Cavenderia fasc...
EFA79156      30 GLLIGQq--QNeTKATFLSMISTPKpfdnqnveYKTTK------------------------------DIDDVWVAEHSR 77  Heterostelium a...
XP_002969121  27 GLLIGR-LgSG-GRDFVVGLVQTPVkedggdaaVLLSSSGNqsRSRs--------------gAGsmalSIDAEWVAEHAR 90  Selaginella moe...
XP_005844179  28 GTLVGR---SSpGKDLLLQALRTPNsdgvaplsVTAGSTAKkgGKGgkp-----------ssSAggglLLDEELVVEHAT 93  Chlorella varia...
XP_008187864  27 GVIIGQ---VIgNNYHVVHLSAMTIwnediqnnKIDVLSYKtlSDL----------------------LANSDTIFQKSL 81  pea aphid
EFP09578      44 yFLLGSf--CSdNDIHVAYASKCPVhssa-----------------------------levnAPekakMLEEDWMADHAE 92  Caenorhabditis ...
EEH51996      96 QATRMLPGGIHVVGVYV---FASDVAMKR-----AssAALRAAIEvgiaeraldvyAPPPPASSSSSsssSSSVLtRHQA 167 Micromonas pusi...
KJE97509     105 QVRQALPGGIDVVGVYIy--APSDLSLKTs----StaAKLRQLVTavgans--------------------lnagePHAI 158 Capsaspora owcz...
XP_003288942  88 QVYRMLYGGISIVGFYIitpDNEILNDDD--------EFFIKLLKfldanmtepikSIQFI------------------- 140 Dictyostelium p...
Q54QH3        83 QVNIMLYGGIDIVGIYMiipDSDTLNEKNn------eSFIMKLLK-----------SIHTIINSKSLqf----------- 134 Dictyostelium d...
XP_004355872  75 QVSKLMYGGVSVVGIYLsvpSIATLTTDS-----KndSLLWKILK-----------SIRDSLISDRKcmrQREEVvVYSQ 138 Cavenderia fasc...
EFA79156      78 LVSKMLYGGINITGICLsvpSINVVNDAN----------LAQILK-----------SIRTTLIQERSyltNII------- 129 Heterostelium a...
XP_002969121  91 QVSRMLLGGLSVVGLYC---LAPDSAFK------QstAILCQVSNavdaat--------------------------sis 135 Selaginella moe...
XP_005844179  94 IVERLLPGGLDVMGFYVl--CPATAFA-------GttALLSALVGqaarel--------------------------sgr 138 Chlorella varia...
XP_008187864  82 EVATLLPGGSHVLGLFFi--VPQDLKSIQ---------------------------PIDIDFYEFNNelnENLLYkKTNE 132 pea aphid
EFP09578      93 RLLRMLPGGIHVVGVAWf--SDKKTFTERkphihKtlGRIQKMNNqit------taNVDESISD---------------- 148 Caenorhabditis ...
EEH51996     168 spERLVVHLSaDARGKVVVKRCALADP--GGDlRHVEHRLGKV---AAS--LIRIDATYDVRC--ELELEREGGKtkTM- 237 Micromonas pusi...
KJE97509     159 tsERYLVHVC-SATKKRIVRTLDVADH--RASlATAEWKAQNT---FAK--FRTISATYHLDS--LVPLAGATGDtgMV- 227 Capsaspora owcz...
XP_003288942 141 -----------SYSLKTNLINGKLTNSslNYRlKSTEIKIINS---LENe-FLKFSCNFPIDI--VLHSKKKIEDi---- 199 Dictyostelium p...
Q54QH3       135 ----------iSYSKKTGLINGKATNStqLYRlKSTEIKVINN---LENe-FLSLHCILPIDI--KLKSKNGMIS----- 193 Dictyostelium d...
XP_004355872 139 tlENMHVLIYlRSTKQYILKSHDMTTVkyEKFkQQSDNIVFPSpniSKTlsCFKLVTSLSIQL--DIDLNNTAVD---Le 213 Cavenderia fasc...
EFA79156     130 --KTLYVLIYiRSTKQYILKSISSASTd-NKFkQITDIKFTQP---TQDflYLSLNTTLNIKM--KLNSSKQ------Fn 195 Heterostelium a...
XP_002969121 136 aqERFVLQIS-TSPRRLACKVCTVEPNg-SSSlKPCEWKLAKI---STN--LQSLTCTYSFDA--SIPVRSAAQAdtF-- 204 Selaginella moe...
XP_005844179 139 lpTMLVLHID-SISGALSLREVAa-----GGSlRPCEFKLAGL---LDQ--MVQLQCRYEIRL--QVPVTRGKQEl---- 201 Chlorella varia...
XP_008187864 133 twNYLMLNYS-TVNKKSYCYSVDFNr---VNGpEKTTYKTVDAvfgSFNndWVTLIGTFNFGAleRLNVGGGPKA----- 203 pea aphid
EFP09578     149 --NMITVFFE-TPSTTPIGAIIDVTNRg-NDSaQKVQFQKLE---------WISLVTNASARVvhNVPVESGKPTd---- 211 Caenorhabditis ...
EEH51996     238 ---RDAAGAAIER-EATRVMASRV-L-LDGTFARPEEDVv----------GvvgadVRAAPVRAELLCpPR------ASS 295 Micromonas pusi...
KJE97509     228 ---VSQVIKAFKP-VLAQLASAET-V-FDSTLASTALDTplp-----------esaKGQSSVTVTIVTaLPsfasfnDLK 290 Capsaspora owcz...
XP_003288942 200 --nVVDLKKQVKE-TFNNLFKDSLfL-IDNEVVKENIISstl------------knSNNNNFSIDILIkQLdsnftiESS 263 Dictyostelium p...
Q54QH3       194 ---FENLKKDIIEiFENQLFKESTlL-IENEFVSGNEIIsq-------------qfKSKSKLNIDLLInQLdsistsSLE 256 Dictyostelium d...
XP_004355872 214 ivlKKQIESMY---YSSELKDSMYlVnGDDSLILPPTTLvknikknnsnsDgtsssSSSSCHQIDLLLnQPilklsnQPT 290 Cavenderia fasc...
EFA79156     196 vemFNEMKQLIEKnLYSQLKKSIVfT-VDNQYCPMDSTGst-------vkLsefanGKSPIVVVDALMsGTdivlgrDSA 267 Heterostelium a...
XP_002969121 205 ---KNKLLSWTAS-EIKVIQSAEV-L-INNALQEGENYSg----------------------DVQLLL-PF--------N 247 Selaginella moe...
XP_005844179 202 ---HAVLQSAADS-AVDQVHGALG-L-VSGQLATDDCQVad-------laDdgsgsGGGGPIPVDLLLqPSsslvfcTAG 268 Chlorella varia...
XP_008187864 204 ---LFSIRDSLLDkFESVLNKSVY-T-FNGCVCDENKTLkd-------veCdeidnLLKNVVKIEFYRe-------vDLG 264 pea aphid
EFP09578     212 --fYSDLMVATKN-FVNNIFHCEFtL-LDGEIRDEKEPLikd-----------ikkNKKTTIEATLFLnPLhnrepgATD 276 Caenorhabditis ...
EEH51996     296 SSSAAAAAsgGGRGGG-----------VTL-RGTITSRCYAYGRESIARACEDVKGDVVNSLRSRLGVLCDLAdsADDAA 363 Micromonas pusi...
KJE97509     291 LTSTSIATttS----------------VSV-SGDVYVTAVVHPKATMAEAQQALLSDLVRTTSIRLAYLAEDLadSLAAQ 353 Capsaspora owcz...
XP_003288942 264 NTPFH----------------------FQF-NSNTNCIAFAHKSEQVSTIYQYIKQDIIKSFESRLDIINDELlnNPSVV 320 Dictyostelium p...
Q54QH3       257 FNFNN--------------------------NNNTHCIAYIHQLEQIKTAFKFIKKDIIKSVESRFDLLFNEIssNNNNN 310 Dictyostelium d...
XP_004355872 291 TISTTPITiaSATLADysdiqqpqpfkLMIqSGIFECKAYINEKETLETAINYLYQDLVGQFISRLETLFDQIitNNRSI 370 Cavenderia fasc...
EFA79156     268 VT-------------------------LHFgNGVQQYRAYALKSESITNTLEYLLHDIINSLESRVELLIDNNdvDQSNM 322 Heterostelium a...
XP_002969121 248 NKEVVQGDnpAIVTGN-----------VNF-KGSVDARAYGFPREPASMAIDAIKEDIIASLRNRIDILCEEAeqQSAEQ 315 Selaginella moe...
XP_005844179 269 GGKAGSGLqhGSAEGPtl-------glILL-AACLDCRACVHRREAATAAVNAIRADLKRSLQARMDALLDAAeqQQEAS 340 Chlorella varia...
XP_008187864 265 NECKNASLkvKRGKGK-----------ILM-SGLCSIAVPFNRNGTIKDAIKAIHEDAMQTFATRLKMHLESMveEESLE 332 pea aphid
EFP09578     277 ELASNMHE-------------------ILF---DIEVRAAVPIRTSVKDAIRAIKHHLVRNLFARVELHYESMevVEEER 334 Caenorhabditis ...
EEH51996     364 AAAAdEKEdsdaaaaaahplse-kgdpfpggdwgpkRRASIALPRRAWARWTvggeaegdarHRGVQLCDYLTADEGAAE 442 Micromonas pusi...
KJE97509     354 ADSS--------------------------------AMLVQPSPVRSLFSLPh---------LPSFPLSDYAYEDDSAEI 392 Capsaspora owcz...
XP_003288942 321 SNQSnSILti-------------------------sNDLPILLPRRVNIQWIgn----------sITICDYLSNHDEIND 365 Dictyostelium p...
Q54QH3       311 DNDQdNIKls-------------------------kESPILELPRRVNIQWLsn----------kISICDYLSSNGTIDD 355 Dictyostelium d...
XP_004355872 371 SKYFtCFVn--------------------------sPTLQVPLPKRVSIGWVd-----------hIDICDYLNEDEPLQD 413 Cavenderia fasc...
EFA79156     323 S-----------------------------------KSTEITLPRRASVQWInn----------nIELCDYLYDAEGYYD 357 Heterostelium a...
XP_002969121 316 APLSlLSHcs-------------------------qDRAEFILPRRVLLPWNe------------LLICDYLLPSETDKE 358 Selaginella moe...
XP_005844179 341 AAEAeQRQqggnsssseaaaafppvhpllsavahcsKPLVVSLPRRAFVAAVppa--------rgVSFCDYLFEGESTQA 412 Chlorella varia...
XP_008187864 333 EEDGd-------------------------------ANIVHETPRRILIIKTe---------GSRFAFSDYVFPGETSQE 372 pea aphid
EFP09578     335 SPKT--------------------------------GITVHQLPRPATTVLYt---------HPAILINDFLFEADNVED 373 Caenorhabditis ...
EEH51996     443 VVARAKEVLGCDVVGG 458 Micromonas pusilla CCMP1545
KJE97509     393 LEQRLSDLFGLKVTAL 408 Capsaspora owczarzaki ATCC 30864
XP_003288942 366 CIERLSDLLQFDSPSS 381 Dictyostelium purpureum
Q54QH3       356 CYKIINDLL--QITSP 369 Dictyostelium discoideum
XP_004355872 414 CKNRLLELLGLNLEEv 429 Cavenderia fasciculata
EFA79156     358 FQQRIQELTNLEFSHQ 373 Heterostelium album PN500
XP_002969121 359 IRERYTYLFGQELPGD 374 Selaginella moellendorffii
XP_005844179 413 LLARLQMLLLMPGLAT 428 Chlorella variabilis
XP_008187864 373 ALYVAGEIL--NLPED 386 pea aphid
EFP09578     374 AQKNFDDMMDLQTSIE 389 Caenorhabditis remanei
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