Conserved Protein Domain Family
Atthog

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pfam18800: Atthog 
Attenuator of Hedgehog
Attenuator of Hedgehog is a integral membrane protein of the tetraspan family that functions as a negative regulator of Hedgehog signaling.
Statistics
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PSSM-Id: 436747
Aligned: 9 rows
Threshold Bit Score: 203.374
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_014770267  25 MPNWIVSE-MGGATSIGLLKTCLTVYERPT-VCYNPEpARAEWFITFICIVLGIGSISSTILLLWFSFWHYRAIRFARWL 102
ESO00937      25 MPYWIISA-NSGNIYIGLLQTCIIIYNRQM-ECFTPDnIQPELVITFVLISGGIICITITICFLIISCWRFNVMKYARWF 102
XP_013400007  25 LPDWILTG-AAGNMRLGLTLQCLTIHNRDE-ICVSPK-LSIEWTTTFVLIIIGILCLTANVMCLMLSHWEDVLKKYAKWL 101
XP_009194397  25 NPDWINTGeSAGALTVGLVRQCQTIHGRDR-TCIPPR-LPPEWVTTLFFIILGIISLTVTCGLLVASHWRREATKYARWI 102
1_pfamImport   1 HPDWINTGaVAGALTLGLTKQCQTIFGRDR-ICFSPT-LPPEWICALFFLSAGIACLAGTCILVVLSHWHRSMLMYARWV 78 
EEC11897      25 LPDWIVSD-VGGDTRLGLLQTCTTLQGRPQ-TCFPPT-LQPEWMLALVCIVLGCVCITATTVLLALSRWNVRVVPYARWM 101
OQR79854      47 LPEWIVSD-IGGDTRLGLLQTCLTINGRPGlTCFPPK-LQPEWMLTLICIIVGCICITATTILLAISHRNLGIVQYARWM 124
KYM98350      25 MPDWIITD-VGGDTRLGLMWSCMTLYNRPQ-VCFKSE-LELEWLLALVCIFIGCILITATVILLMLSHWDRTVIPFARWV 101
XP_320325     25 MPDWIVTS-VGGETRLGLMWTCMTLYNRPQ-VCFTPE-LQPEWLIALICIFVGCICITTTIILLASSNWDRNVIPYARWV 101
XP_014770267 103 GFVAMILFCMAAVIFPIGFNMDQIGGLPYQLPHNFEVGISYIFFVLALWITVVSELFVGKVCVP 166
ESO00937     103 GFVAMVMFCLAAIIFPISFYMDQIGGEIFQLPPSFHVGIAYIFFVLALWITVVSELFAGKVCLP 166
XP_013400007 102 AFFAMISFCTAGIVFPMGFYVDEIGGYPFQLPTQSQVGVSYVLFILSIFFTIISELLAEQICRP 165
XP_009194397 103 AFTGMILFCMAALIFPIGFYINEVGGQPYKLPNNTVVGSSYVLFVLSIFFTIVGLLFAGKVCLP 166
1_pfamImport  79 AFSAMSMLCVASILFPVGFQSPVIGGAPFLLPRSANVGNSYVLFTLSIFSCFTGLVVAARVCVP 142
EEC11897     102 GFSAMLLFCLAAVIFPVGFTMDEIGGEPYQLPSSHQVGLSYIFFVLALWITVISELFAGKVCMP 165
OQR79854     125 GFSAMVLFCVAAVAFPVGFGTDQIGGEAYQLPSSHQVGISYILFILALWVTVISELFAGKVCMP 188
KYM98350     102 GFTAMILFCHAAVIFPMGFYIDEIGGQPYQLPNSHQVGIAYILFVLALWITVISELFAGKVCLP 165
XP_320325    102 GFTAMVLFCLAAVIFPLGFHVDEIGGQPYHLPHSHQVGISYIMFVLALWITVISELFAEKVCLP 165
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