Conserved Protein Domain Family
GCOM2

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pfam15328: GCOM2 (this model, PSSM-Id:405915 is obsolete and has been replaced by 464649)
Putative GRINL1B complex locus protein 2
This protein family is named Putative GRINL1B complex locus protein 2. GRINL1B is short for: glutamate receptor, ionotropic, N-methyl D-aspartate-like 1B. The name indicates what sort of receptor it is thought to be, a ligand gated ion channel specific to the neurotransmitter Glutamate. This family of proteins is found in eukaryotes. Proteins in this family are typically between 325 and 463 amino acids in length. The protein is thought to be the product of a pseudogene with a role in helping assemble a gene transcription unit.
Statistics
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PSSM-Id: 405915
Aligned: 33 rows
Threshold Bit Score: 97.1915
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_012657417         28 LKRQERLLRNEKFICKLPDKGKKILDSVAKLKAAIAEHEEVRGKSKLFHPVSIDCKLRQKAVA----------------- 90  small-ea...
XP_023607375         12 piKFICKLPDNGKKIRDSVVKLRAVIAEREEVRGKSELFHPISLDCKPRQKAIAVDVDTDKAQ----------------- 74  little b...
XP_001999387         35 RDRQSNILASKKRLESLPDKGRRIRESHEKLLAEIQRRNDVEATANLLGELNIASKGKVTLNNlewhgkts-pgksdvtd 113 Drosophi...
WGS:AANI:GJ22715-PA  35 KDRQSNLLASKKRLQSLPDKGKRIQESYEKLLAEIQRRNDVEATANLFGELNIASKGKRTLNNlewhgraa-vdssnlsd 113 Drosophi...
WGS:AAQB:GK13803-PA  41 KERQGKFLTFKKRLDQLPDKGRRLKESYDKLLDEITRRDDVEAAARMLSELNIASKGRVALDNlewngkm---tddhvad 117 Drosophi...
EDW38512             39 RDRQSKFLSFKKRLLQLPDKGRRLQESYDKLLDEIRRRDDVEATAQMLSELNIASKGKIALNNlewngreivdegahved 118 Drosophi...
XP_002043333         39 KDRQSHFLSFKKRLHQLPDKGKRLQESYDKLLAEIRRRDEVEEATRMLSGLNIVEKGKIALNNlewngrnt-degahvdd 117 Drosophi...
WGS:AAPP:GF16542-PA  39 RDRQAHFLSFKKRLLQLPDKGKRLQESYDKLLDEIRKRDEVEQATRLLSGLNIAEKGKVALSNlewngrta-degahvdd 117 Drosophi...
XP_011268939         40 vERQNKILANKQFISKLPDKGEKIVRFRDKLLKELEHRNEVETAANLLSQLNIASIGKAAMTKlewtgkyndkndenttk 119 Florida ...
EGI69710             27 LERQKKILANKKFISKLPDKGEKIINFYNKIQKELEHRNEVEEAANVLSRLNIASEGKMAMSKlewtgkynerddenmtk 106 Panamani...
XP_012657417         91 EVDVNADKAQNSDQILDTSSLV---PGSSSVDNIKSSQTTSqKQELGHPTHRGDEETPEA------ECTVNECPASRNTA 161 small-ea...
XP_023607375         75 -NSDQILDTSSLVPGCSSVDNI---TSSNTASQQGLVHSSH-RGDEEAPQVGYPVNKCPA------SSSSATAPSPPEAR 143 little b...
XP_001999387        114 L--LDSDDEQDIDPLRIIAQGT---MHQRQVKVLPPPATLItPEDVVDIASFRQEQPSDSldssqtNESASS--SGQ-DD 185 Drosophi...
WGS:AANI:GJ22715-PA 114 L--LDSDDEQEMDPLRVIAQGT---MHQRQVKVLPPPATLItPEDVADIASFRQT--PNSldstltDQSASSSLSGQ-EC 185 Drosophi...
WGS:AAQB:GK13803-PA 118 I--LDSDDELEMDPLKIIAQGT---MHEKKVKVLPAEVTLItAEDLAEIETFKGASTSPD-------------------- 172 Drosophi...
EDW38512            119 I--LDSDDEL--DPLRIIAQGT---MHEKRVKVLPPPESLItAGDLADINTFKKT--ADSpdsaleGQSATS-------- 181 Drosophi...
XP_002043333        118 I--LDSDDEVEMDPLRIIAQGT---MHEKKVKVIPPPTSLItADDLADIEEFKKP--TDSpdsalaGHSDTS-------- 182 Drosophi...
WGS:AAPP:GF16542-PA 118 I--LDSDDELEMDPLKIIAQGT---MHEKKVKVIPPSASLItAEDLAEIEDFKKP--TDSpdsalhDHSDTS-------- 182 Drosophi...
XP_011268939        120 VVELDSDDEE--DPLKILAQPTgtgVHKKKIIHIIPEESLIkPEDIVEIESFKTD------------------------- 172 Florida ...
EGI69710            107 IIDLDSDDEE--DPLKILAQPTgtgVHKKKIIHMVPEENLIkPEDIAEIETFKTD------------------------- 159 Panamani...
XP_012657417        162 RVPSSSAASEHFPGHCVSRQAEDNFSSSDSLFIDKFQRITIEDQGEHNSEENTSAENLTglsGLCSGTQKKPHYMEVLEM 241 small-ea...
XP_023607375        144 ECLPQPPVSGPAEDNSTSSDDLFVDRLQRITIADPDEQHSEENTRTENLTGLRSGTQKK---PHYMEVLDMRAKNPVPPP 220 little b...
XP_001999387        186 SKIIPAEIIEIDVGKLVGNRPTEAT-------LEQHALYLIDKTE---LH-AVKDREKF-----------LPF------- 236 Drosophi...
WGS:AANI:GJ22715-PA 186 SKTIPAEIIEIDAATLVDKHSPGTT-------LEQHALYLIEKTE---LPVSATAREKF-----------RPF------- 237 Drosophi...
WGS:AAQB:GK13803-PA 173 -STVPADLIEVKLSRLALTKESNDSAPAPTLPLEQHALYLIDKTEHQRSDNDPPVREKF-----------KPF------- 233 Drosophi...
EDW38512            182 --SIPAEFVELDACLVAAKYPQESRS---YPPVDQHSLYLIDITE---PKERSAGREKF-----------RPF------- 235 Drosophi...
XP_002043333        183 --SLPAEIVEIDASQVAAKLSKEL-------PPDQHALYLIDKTE---TNVNTP-REKF-----------MPF------- 231 Drosophi...
WGS:AAPP:GF16542-PA 183 --SLPAEIIEVDASIVAAKLGKEE-------PLEQHARYLIDKTE---VNINPSAREKF-----------KPF------- 232 Drosophi...
XP_011268939        173 -----------------------------NCLDVEHVKYIIDKVE--KAQETNKKKEPF-----------KPY------- 203 Florida ...
EGI69710            160 ------------------------------LLDTEHVKYIVDKVE---KVQEVKKREPF-----------KPY------- 188 Panamani...
XP_012657417        242 RAKN 245 small-eared galago
XP_023607375        221 RQFK 224 little brown bat
XP_001999387        237 RTTv 240 Drosophila mojavensis
WGS:AANI:GJ22715-PA 238 RTTi 241 Drosophila virilis
WGS:AAQB:GK13803-PA 234 RTTv 237 Drosophila willistoni
EDW38512            236 RTTi 239 Drosophila persimilis
XP_002043333        232 RTTK 235 Drosophila sechellia
WGS:AAPP:GF16542-PA 233 RTTv 236 Drosophila ananassae
XP_011268939        204 KTTK 207 Florida carpenter ant
EGI69710            189 KTTK 192 Panamanian leafcutter ant
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