Conserved Protein Domain Family
DUF4153

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pfam13687: DUF4153 
Domain of unknown function (DUF4153)
Members of this family are annotated as putative inner membrane proteins.
Statistics
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PSSM-Id: 463956
Aligned: 101 rows
Threshold Bit Score: 60.0296
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q21MZ4         15 LLISLLQGLGLLvlhesveysfWPGTsfgPLFG--LIAFALIAPTMLLLTLt------rENGGLSAKWIAPFSLLCAGla 86  Saccharophagus...
WP_012290927   23 VLFAIFIATIFSimeiwkiefnVLNStliVDLIisSLYFAMSYMIVKLIITdknieitnGQKALVYAIVSVIMGLLCYfl 102 Finegoldia magna
Q11HD8         45 QAALLIADVHLFr---------FVAEseaSEVF--VVGLVAGALAALAAALfg-----eARGLSAVARIAVGLAAGFFaa 108 Chelativorans ...
jgi:Amet_2923  26 LFGALAVAVSIFinh-----ssIPFGktrEIYN--HIVMALSLGIPLSLCIyvlfegrtKSEKHHRILAHVGSGLLLIly 98 
WP_012635424   33 ILMIILANEYLY----------DFDKntvRLFS--RLVMTSSLGFPLFLCInllfrrwqGLKAGTRNLIRFTGAVALIly 100 Halothermothri...
jgi:Lebu_2228  34 ITGIYIAEVRNF----------QSDEfieVNLL--LFGSIFITGMCEIIREkyfyeknkWLVRGIYSFITLVLSIIFYvd 101
jgi:Dfer_3998  30 VKSILLIWLTEIp---------YTDGaarSQLT--RLSFIATLALPLALAIr------lSEERQQWKSYLRPTLISLAai 92 
jgi:Phep_0206  32 ATLAWCIVVNPT----------RAVKpieEQLI--EFIAICNLGLTLLLAAdlyaevnhYSRAKQWGLRLLMVLICTGly 99 
WP_015757447   30 ICATILTCYMIS----------LHKS---PDLT--IQKLMFAFLFGSFLGVta-----qFACERFWHLAITRLVVYALsv 89  Desulfofarcime...
Q0AX67         30 ICCTTLTCYMIS----------LHKS---PDLI--VQKLMFVFLLGSFIGVsa-----qFACERFPRLARLRWALYALsa 89  Syntrophomonas...
Q21MZ4         87 yYVGvqat-ppdkVESGALIFTlv--------vTMGLasfkalMYIQQRAGRQ---HITYGALFTLSwqnfLVLALGGLF 154 Saccharophagus...
WP_012290927  103 iIKVdkslylknqITQMGLFFAl----------FIGM------FVAGHFNTEIdyaDYAVKIILAII----ESLIYCVTI 162 Finegoldia magna
Q11HD8        109 aLVSf-------pETFLSIEWAl----------VGALiglvlvAPFIGRGTSGsfwMFSAHAAFAAL----LGLLTLLLF 167 Chelativorans ...
jgi:Amet_2923  99 yFFFlkdmemvtvTRYIGHSIFl----------YLTF------TFIPYLEKKEnyeRYVVKLLTRFI----VTYLYSVIL 158
WP_012635424  101 fFFLskgtetvttSRFLAFNLAl----------YLLF------LVIPYFYKREnfeLYVVKLFIRVL----VTIIYSVIL 160 Halothermothri...
jgi:Lebu_2228 102 yLQTn--------DYNNFKFWAl----------IPISiilfvlIPILNRENKE---KYLQSEFSDFV----ITYIFAAVL 156
jgi:Dfer_3998  93 lLTA---------YYFTLDTEPnqtdtyrflmlLAGAhlvvsyAPFIGTSDKEnfwQFNKTLFLQFL----NASLYAGTL 159
jgi:Phep_0206 100 fLLNp--------YFYLADTYRiallafafhllVAFA------PFIRHGNLNGf-wQYNKSLFLRFL----TAALYAAVL 160
WP_015757447   90 lLILg--------YYLIISPVPaidygvrtrtsVAIFslfcvfIWLPSFQGKFdfnSVALIHFKSAF----TSILYAGVL 157 Desulfofarcime...
Q0AX67         90 lLTLg--------YYFIISPAPtidygvgartsVAVIsmfcafIWLPSYQGKFdfnSVALIHFKSAL----TSILYAGVL 157 Syntrophomonas...
Q21MZ4        155 TLVIFGLLKLWGGLF--NIIGIDYFSDLfkqkW--FLYPALSLGLGFGIILLRSQLAI--ISTIAN-------------- 214 Saccharophagus...
WP_012290927  163 FVGIVAILYTTKELF----KLNFNLSNL-------IVTCAVVIFLLLNATIILSKFPL--KYCEENlkikw-------lt 222 Finegoldia magna
Q11HD8        168 AGGISAIMASLTVLFg-FEVPDDLYAYV----W-------AFTGLFAAPVFAMGQFPDrfDEQPNQvmtgf------mdr 229 Chelativorans ...
jgi:Amet_2923 159 YLGIAAILGTINLLFd-AGIPGKFFFDV----F-------LIVVGIFAPGFFLADVPV--RNEEISpesy--------pk 216
WP_012635424  161 YLGLSAIFLTINALL--DIPVSHRFYLNt---W-------LITAGIFAPVFFLGGVPE----QGQKinpdd------ypt 218 Halothermothri...
jgi:Lebu_2228 157 FVGIAIVLTTISYLFf-SSNNDFFFRLT--------TYSFWFIAEVFGASLFLSLLKK--PDDDLEnykf--------ps 217
jgi:Dfer_3998 160 YIGLLIAVQTVKYLFniNYKFNIELDLL------------IVVSSFFHTVFFLSKIPA--PADFKNdypvg--------- 216
jgi:Phep_0206 161 FAGLAIALVAIDGLF---------SVKIg---WqtYMRLFAVVTAGFMTIFFLAGVPE--SFEGPDteet-------ypk 219
WP_015757447  158 ASGLAAIIGAINILLf-KVNSDWYGYMM------------AIVWILFATIYYLSLLPH--FDSESEtdhayageashypr 222 Desulfofarcime...
Q0AX67        158 AAGLASIIGAVDILLf-RINSDAYGYMM------------AIVWILFATTYYLSLLPR--FNSETEfdqtyaqeasqcpn 222 Syntrophomonas...
Q21MZ4        215 -IWHVLTKFLLVLLVFIALLFLLFL---------PfE--GLSALWQTGKGSL--LLLWLMALILFFINSV-YQSEETNRA 279 Saccharophagus...
WP_012290927  223 pfKFLFTRIIAPLFLIYGSILLLYIikvvvlktiP----NNIITNL---------ILWYGLLSVVVLFVS-------KTV 282 Finegoldia magna
Q11HD8        230 gMRALGDFIAAPLLIVYALILHFYAlkivvtgevP-E--GQI--------GW--LVLVYGLCIFGALLVI---NPFFDQA 293 Chelativorans ...
jgi:Amet_2923 217 vLSVLLQFIILPLLSIYTLILYIYFgqilltrelP-------------QGLIgnLVLWYSIVSTVVLFFI-----YPLRK 278
WP_012635424  219 fFEILLLYIVMPLITIYTGILYIYFikilitaqwP-------------RGLVahLVLWYSALSTVVMFFI------HPLL 279 Halothermothri...
jgi:Lebu_2228 218 iFNLLIKFVIIPLIVIYTGVLYIYMakvvismqlP-K--GLI--------SH--LVLWYTAFSVIIMILItPFTQKDKF- 283
jgi:Dfer_3998 217 -lkvfTQYVLLPLEVVYLAIIYTYLgkimfqwklP-E--GGV--AYLVLAF--------SVAGIFALLLL---YPLRQSM 279
jgi:Phep_0206 220 gLKIFTQYVLIPLMTIYLAILLVYEikiiflwelP-------------KGLV--STLILGYAVFGILSLL-LIYPIKEKE 283
WP_015757447  223 fLEILVSYIAVSLVAAYTLVLFAYFikigftmkwPsGqlGPMILAYSAAGLV--IYVLASRLKNRLAVLY---------- 290 Desulfofarcime...
Q0AX67        223 fLEILISYIAVPLVAGYTLVLLAYFvkigitmnwPsGqlGPMILAYSAAGLI--IYILASGLENRFAVLY---------- 290 Syntrophomonas...
Q21MZ4        280 YpiwLHRFIYVGIACLPIYSVISFYGLFARVGQYGLTLER-----CWAWLIWGMLTLFAAGYcvgiirkRDNWVAQLSkv 354 Saccharophagus...
WP_012290927  283 EdkfIKIYDKVQPLILLILSGMMFYSIGIRISYYGITEGR-----YMVVIGGVFIVISMIYY---------LFFNKKT-- 346 Finegoldia magna
Q11HD8        294 rt-pTRFFLRVWPFFLPVPLVLLFYALGVRISTYGVTPERyllglFGLITALILVIQLVPRLr------GDIRV------ 360 Chelativorans ...
jgi:Amet_2923 279 NsqwMKYFITCLPKLIIPLLGMMFVALWIRINAYGITEGRyfvllIGLWVTCMMIYYALKRD------------VKNI-- 344
WP_012635424  280 YkkwVKQFIKWFPVTNIPLLIMMFVSIGKRINAYGVTENRyyvvlLGLWILGIMVYYILSSKk------RNIILP----- 348 Halothermothri...
jgi:Lebu_2228 284 ----LGNFKKYFPYFSIPLIFASLFALFQRIYQYGITEKRyyvliLIFWLLFCVILFIRKMNi------TGIFISLIA-- 351
jgi:Dfer_3998 280 TerwVSIFSRRYYVALVPLIVLLFIGIFRRIIDYGITENRyivavLAFWLAGITLYFLSGKRd------DIRWIP----- 348
jgi:Phep_0206 284 GngwMKLFSRFFYVMMVPLVVLLLLAVWKRVGNYGITESRyiliiLAVWLTFITAYFLVSKKq------NIKIIP----- 352
WP_015757447  291 --------QLIFPKVLIPVVIMQLISVYIRLNAYGVTESRyyvalFGIFSIVVGIVLSFRPV-----------VKNSI-- 349 Desulfofarcime...
Q0AX67        291 ----QRIFPKVLIPIVVMQLISVYIRLSA----YGVTESRyyialFGIFSIVIGIVLSFTPVk-----kNGL-------- 349 Syntrophomonas...
Q21MZ4        355 nigMGLVVLMVtLLvnSPLLDF-RKLSVNSQLARLDSGLVtieeFDFHYFRNhLA--RPGYLALIDL 418 Saccharophagus degradans 2-40
WP_012290927  347 ---YITIPTTL-LI--LTLISS-VGPVSAYNISKIDQKNR----LEKMLI-------EENLLVNGEI 395 Finegoldia magna
Q11HD8        361 ---IAGVPVAA-LI--LGGFGP-QGAVGVSIQSQSA--------------RF-LS--IVENPPVEGP 403 Chelativorans sp. BNC1
jgi:Amet_2923 345 ---VLAMTLAI-----VALATV-TGPWSAYSISQIS--------QNNRF--------QEILKRYDMI 386
WP_012635424  349 ---LSLAIIMV-----LAVIGP----WSSFSISRYS--------QNKRFA---------AILSRYRM 386 Halothermothrix orenii
jgi:Lebu_2228 352 ----CVVIAVY-TP--FSAKSV-SNFSQKERLKRML--------VKYGAL-------KDGKISKITQ 395
jgi:Dfer_3998 349 ---VTLSILCF-L---LPIGPW-NIFVVAKNSQLKR--------FEAILVRN-QI--LDSRHQIARQ 396
jgi:Phep_0206 353 ---VSLCILAL-----LTTYGP-QSAFSVSEYSQLA--------RLKKLMASkVKkdTDQRASVVRY 402
WP_015757447  350 ---IALFGAGF-AI--LSVIPP----VDAFTVSRVS---------QINRLENmLQ--AASVLVDGKI 395 Desulfofarcimen acetoxidans
Q0AX67        350 ---IALLAAGF-AI--FSILPPvDAFTVSRNSQISR--------LENYLQ-------TEGVLVNGKI 395 Syntrophomonas wolfei subsp...
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