5WB5


Conserved Protein Domain Family
IF4E

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pfam01652: IF4E 
Eukaryotic initiation factor 4E
Statistics
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PSSM-Id: 460281
Aligned: 259 rows
Threshold Bit Score: 66.3951
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
pfam01652 is a member of the superfamily cl02106.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5WB5_A        22 KLQRAWTLWYd--------------SPSTy--------NTEN--------WE-MSLVPI-MTVHSVEEF---FVM----- 61   Leishmania major
EAY00208       7 NFIQEWQFWVit------------cRFTD----------KTQ--------YEiEPIIKV-RSKSKFAEY---LAS----- 47  
XP_653262     34 YFSKEWCFYHnt------------tIKSN----------TSE--------Y--CPFGKLiGKFKTLRQFcqiWNI----- 76  
XP_007674608  16 PLVHSWDFYHdrqdrttsknlsnasIRHQdad----gqETES--------YE-ARLEHL-AVIHDVRQF---WNV----- 73  
EGR52127      46 PTQHYWDVYFdrp----------keQKPEsgg---gggTGQE--------YT-AQLEKIgAPIESVQDF---WR------ 94  
EJT80523      52 PTQHYWDVYF---------------DRSQ---------NADNnnqggdgtYK-VQLEKLpTQIESVQDF---WRY----- 98  
EEQ82324      14 LCDTNYVVTYkei----------ddTEIN----------KET--------YN-KDLEII-CEIESINNL---VYF----- 55  
Q233I3        33 QFKDTWVIWEslkqek-------------------vdknaQSn------nFL-DNNFAI-FDFNDMESLakiWRTrirtv 85   Tetrahymena th...
EGC37659      70 TLPEKWILWYd--------------TKKAintt--tteSDGE--------YL-QNVEKV-GTFNTLKEL---KNL----- 115 
EGG21781     111 EFTQPWVVFFd--------------KKNKekitpapanPGENd------qYL-QNIKKI-GTFNTLNSL---KEL----- 160 
5WB5_A        62 ----------LRYMKP--L-HALRTSSQYHFFQEGVKPMWE-DPANKKGGKLWVNLditsangrssnnntsgtsaaDGsa 127  Leishmania major
EAY00208      48 ----------LPDVLHlqPkQNS--KISLAFFSDNIQPAWE-DKANTEGGCMYFTL--------------------QDkl 94  
XP_653262     77 ----------LSNSKQ----HYS--NHQIQIFVNGV--THEfNEENVEGGKFTVEI--------------------EK-- 116 
XP_007674608  74 ----------WNNFQI----ADLALRDSVHLFHKGVKPVWE-DPRNTEGGSWTFRV--------------------SKd- 117 
EGR52127      95 ----------YNNNTP--V-ENIKMRESLYLFKSGFRPVWE-DRRNINGGSWTFRV--------------------PK-- 138 
EJT80523      99 ----------ANNTPV----QNMKMRDSIYLFKQGFKPVWE-DRRNINGGSWTFRV--------------------HK-- 141 
EEQ82324      56 ----------LERLKA----FETVRDCYINVFKEGIQPLWE-DENNKNGCNWSLVL--------------------KK-- 98  
Q233I3        86 sqiftfdgssWRFLHE----KKMRSTEAICIFKKGIVPAWE-DPKNSRGGEFQAMF--------------------ESv- 139  Tetrahymena th...
EGC37659     116 ----------WDSLKT--P-LEV--IGNISIFKEGIEPAWE-DSKNKDGGKISVNYl-------------------KDn- 159 
EGG21781     161 ----------WKGLSS-------PVDSNISIFKEGIEPAWE-DVKNKDGGKYSVNYm-------------------KDh- 202 
5WB5_A       128 aEAktdLDKAWENVLMATVGEY-LDCVdkkdt--ptepfVTGIVM--SKR-KYHN--RLAVWVSDAS-A-T-DKIEAL-K 195  Leishmania major
EAY00208      95 kER---AQDLWEYLLAAAVSGE-LNNWlindv---kgneICGVIV--SPKvYNAY--SFEIWTRSNNqN-NqRFQAKL-Q 161 
XP_653262    117 -EY---KDGLFQLIIDGVICKT-MKHSf----------lIQGISL--IQQ-ENKY--KMSLWVSYL----EgEEQADI-L 171 
XP_007674608 118 kG----QA-FWTELGMLAIGEQ-LQAAvdddtrttfrddICGISV--GVR-FNSF--LVQIWNRDG------EHAKGIeG 180 
EGR52127     139 -AI---GPDFWTRIQLLAIGEK-LQSVide------adqICGVGL--SVR-FNSH--LITVWHRDS------SKQNSI-D 195 
EJT80523     142 -NI---GPEVWTKVQLLAIGEE-LQGAlee------gdqICGVGL--SVR-FKAH--LISIWHRDS--S-KqKSIDGM-L 201 
EEQ82324      99 -EI---CQRYFEKLIVRMCTGF-FRVIvp--------sgVVGVYK--DNRf------KLSIWSKTI--PqPsEHVNAI-- 153 
Q233I3       140 dQNpevIDNIFKDVLSIILCEN-YAFYn----------eTNGFRMvdKAR-DSKAkiRLEIWFDFCDdK-SeSTTKKI-- 204  Tetrahymena th...
EGC37659     160 gDFskvFNA-WFTLFTTIVYTT-FENYe----------qSNGIVL--SIR-GWGA--SISLWNGSA--E-Q-DKVQSI-K 217 
EGG21781     203 pEFsrvLNN-WFSLLTTIVQESkWEHYs----------qTNGIVL--SFR-SWGV--SINLWNDNSD-N-Q-DAVQAL-K 262 
5WB5_A       196 ------KALT----KEAS-L--APIAS-------MVF 212  Leishmania major
EAY00208     162 ------EELK----KLLN-L--ESDLK-------IQW 178 
XP_653262    172 ------NEFN-----LLI-LksGSKQT-------AHY 189 
XP_007674608 181 lfhavvENLK----EELK----PREGT-------YYY 202 
EGR52127     196 ------AIIKc--------I--LEELppelqpkqdNY 216 
EJT80523     202 ------AVVL----EALSsL--PEDQK-------PKP 219 
EEQ82324     154 ------NELK----SALD-I--NFNVS-------FQY 170 
Q233I3       205 ------AELNkiftEIIKkH--QQNVD-------LSY 226  Tetrahymena thermophila SB210
EGC37659     218 ------ESFH----NILS----------------IKY 228 
EGG21781     263 ------DTIQ----NILK----------------VKY 273 
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