1TWH,5X50


Conserved Protein Domain Family
RNA_pol_Rpb8

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pfam03870: RNA_pol_Rpb8 
RNA polymerase Rpb8
Rpb8 is a subunit common to the three yeast RNA polymerases, pol I, II and III. Rpb8 interacts with the largest subunit Rpb1, and with Rpb3 and Rpb11, two smaller subunits.
Statistics
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PSSM-Id: 461079
Aligned: 112 rows
Threshold Bit Score: 129.916
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1TWH_H                         10 FQVSEVDP--GRYNKVCRIEAASTTQdQCKLTLDINVELFPVAAQDSLTVTIASSLNLEdt---paNDSSATRSWRPpqA 84  baker's yeast...
EAY23345                        8 FRCTAVDPdgKQFDDVSRIKATTDEG-DYELVLDYNCFIYEIKQDQLFQLNISTQLHSD-------EASRAEEHWHPsiV 79 
EIE86510                       12 FDIKDLDPqgKRFDRVSRLIARSENY-EMDLTLDFNSEIYPLNTGEKFSFVLASSLSLEasan--tggvEKRESWREraP 88 
XP_004997195                    8 FTVKAKDPkgRKFERVSRIVCEAFMT-GFELILDLNTQLYPMELDEQFSLCLARSLDDEaa----psSGTYVQN------ 76 
WGS:AAGF:cds.TTHERM_00549610A  12 FKLEEIKKeeK-FSKVERVVLVSDN--NIKIEIDIHTDLYSMKKGNQYWVMITSSLGNFqedkgi---------fvseef 79 
A0DFX5                         13 FKVEDIDQagQSFKRVSRIKCKSKSG-EVDMELDVNIDIYPIDKGSEYRVLIVRSLGISqemdqgkYKPEFSQ------- 84  Paramecium tetraurelia...
XP_656855                       8 FKVIAKDIggKIFEGVSRFKLEGE---DLTVFVDINTDLFPLEEHDRIKLDLTKTLNRDgspm-dihQGYSDNF------ 77 
XP_015785465                   11 FDVLDVNCdtSVAENVNRIHCEGIET-QTDLLLDLYSPVFNVKKGEKINVLLVKEIQSGkrklendds----dmevydan 85 
Q384M6                         12 FTVAAVNEegTVYSRVSRVRCTGEGG-GLIITSDVNTGEFPLHSGDRLTIILTDSIELS--------EQAGSKHYDQsvY 82  Trypanosoma brucei...
Q4DCA7                         12 FTVTALNPdgVVYIKVSRIQCKNERG-NITITSDINTEEFPVSLDDRLTIMLANSIELS--------GQSGAKHYDQsvY 82  Trypanosoma cruzi...
1TWH_H                         85 GDRSLAD------------DYDYVMYGTAYKFEEVSK----DLIAVYYSFGGLLMRLEGNYRNLNNL--KQE-NAYLLIR 145 baker's yeast...
EAY23345                       80 ENSTLAA------------SYEYIMHGKVYNYEEQPEt---NRATVYVSYGGLLMSLTGDRNTIAGI--QRGkEVYLLIS 142
EIE86510                       89 GERDLSD------------EYEYVMFGKVYKFEDSNKgaaaQQVSVYVSYGGLLMCLEGDYRHLQNL--TVGeNIYLLIR 154
XP_004997195                   77 RESSLAD------------SFDYVMHGTIYRVEEKE-----GQVAVYASYGGMLMRLKGNRSALMKPglELDsSLYLLIR 139
WGS:AAGF:cds.TTHERM_00549610A  80 DRESIKD------------KFEYVMHGKIYNMNSDNKa---KTVSIFASFGGLLMKVSGKDEDLKNF--NVDsRIYILIR 142
A0DFX5                         85 IDNELLE------------KFQYAMFGRVFKMIKDQN----KMINVFASFGGLILKLSGKSEELDKF--ADDqRVYLLMR 146 Paramecium tetraurelia...
XP_656855                      78 GKNTKMD------------DFDYVMSGMVFKFVENKNd---DNLSVIASFGGLLLMLYGKPEKLSAY--NMKdQVYLLIR 140
XP_015785465                   86 GQSSTVDpldtssilneysKFKYIMHGKIYKIENKMIstnePIIAVYASFGGLLFRLQTSLENHSDW--HIDrNLYLLIR 163
Q384M6                         83 HRSTRLD------------DCDYAMHGRVYSMEVNESs---LDVTVHISCGGLLTQIVGKPQSLKDV--HYNsDVYILMK 145 Trypanosoma brucei...
Q4DCA7                         83 HRETRLQ------------DCDYAMHGRVYGHEVDESs---LDVKVHISCGGLLTQVIGTPQSLRDI--HYNsDVYILIK 145 Trypanosoma cruzi...
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