2I1S


Conserved Protein Domain Family
PRiA4_ORF3
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pfam07929: PRiA4_ORF3 
Plasmid pRiA4b ORF-3-like protein
Members of this family are similar to the protein product of ORF-3 found on plasmid pRiA4 in the bacterium Agrobacterium rhizogenes. This plasmid is responsible for tumourigenesis at wound sites of plants infected by this bacterium, but the ORF-3 product does not seem to be involved in the pathogenetic process. Other proteins found in this family are annotated as being putative TnpR resolvases (Swiss:Q9LCU7, Swiss:Q50439), but no further evidence was found to back this. Moreover, another member of this family is described as a probable lexA repressor and in fact carries a LexA DNA binding domain (pfam01726), but no references were found to expand on this.
Links
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Statistics
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PSSM-Id: 462319
Aligned: 95 rows
Threshold Bit Score: 87.2714
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2I1S_A                    8 VYHLKLSIKGITP-QIWRRIQVPENYTFLDLHKAIQAVMDWEDYHLH----------------------------EFEM- 57 
WP_013688615              3 aLKFRVLLDSEKDqEIFRDIIINEDENFESFYRTILNSFNFEGQEIG----------------------------SFFMs 54  Fluv...
jgi:Clopa_3812          176 AIKIKVKLDLEKF-HIWRSAIVPLNYTFGEFHQVMQKLFDWKDYHLH----------------------------DFLVy 226
jgi:Hprae_1152          177 AAVLKVELELGEY-QAWRKVIVPLNYTFRELHNILQQLYNWQDYHLH----------------------------DFFIy 227
Q8G640                    8 AFRFRVTLRLDGR-ECWREILVPASLTFFDLHAVLQECFMWYGEHLF----------------------------CFCA- 57  Bifi...
goetting:EAL2_808p02250 185 AFELMVSLDLEVY-KAERKLIVPADLEFAQFHKVLQYVFNWNNYHLY----------------------------DFAIi 235
WP_014269791            181 sLQVSVTLELEHE-NVFRRLIVPSCISFFQFHTILQEIFEWQNCHLH----------------------------EFSLg 231 Spha...
BAK15243                187 LYQLNIQLDLDGH-EIWRRVQIPANYSFRSLHNLIQIVFDWQNYHLH----------------------------EFYVe 237
CDC60545                112 VYTFHIAYEGFED-KIWRTVEVSGNNTLAQFGYLILATFDLLEYHAF----------------------------EFTYq 162
CDB30793                  6 IYQFYAELKDYEP-KIWRRFQVPENITMARLGYILMTMYEMKANHLFcvtvpirdnvkldetlsgvgsvfpdkswRFEIg 84 

2I1S_A                   58 ----------------------------------VNpktgmlDKIGAeg-------------------ddFDAFGGPLVS 84 
WP_013688615             55 nddwdkghe---------------------------------------------------islmdmsysdEDQELTSVMS 83  Fluv...
jgi:Clopa_3812          227 rgdepiin-----------------ivgseedfeYQ------M-------------------------------DTPMVM 252
jgi:Hprae_1152          228 skekdatknwnhdeyhkdgykailslamnqenfeYN------Rdq-----------------------lnFAAEDFEQAV 278
Q8G640                   58 -----------------------------------A------FPNGKqvqveelwgeepsyheakyeqymPVEPLPEVRI 96  Bifi...
goetting:EAL2_808p02250 236 dektkntaa----------------------------------------------------rlvpteedlEYDESAVLME 263
WP_014269791            232 nndkitm-------------------------------------------------------ddfddeigLYGDGIQIRE 256 Spha...
BAK15243                238 rkdnrnlkiv--------------------------------------------------mdddpntlefADSSADEIVQ 267
CDC60545                163 ---------------------------------------------------------------------dISYVLPMILD 173
CDB30793                 85 ne------------------------------------------------------------------elFPGEGEKVFD 98 

2I1S_A                   85 EK---------KAKLSDY-FtLENKeALYTYDFGDNWQVKVRLEKILPRkeg--veYPI-CTAGKRAAVPEDSGGVWGYE 151
WP_013688615             84 ES-----------KLTDF-MeAPDQkIILVYDFLRMWIFLIELQERIEEtl----dKPKiALA-VGIAPPEDSKIV---- 142 Fluv...
jgi:Clopa_3812          253 ES---------KVKLSDY-L-PEYKsLKYRYDYGDNWEHIIKVEDAIFDyd---knYSY-CLDGSGDKPPEDVGGEHGYE 317
jgi:Hprae_1152          279 EN---------EVKLKDV-L---PArIKYIYDYGDNWHHYLETVEIIDDyn---knTPS-FLEGEGTAPPEDVGGF---S 338
Q8G640                   97 AS---------ETELGDV-F-PKARtARYYYDYGDDWIHDIKLLRTYRSvh---vaDPQ-LWDGAGDAPPEDVGGVYGFE 161 Bifi...
goetting:EAL2_808p02250 264 GH-----------TLAEF-F-PEHKqMLYTYDMGDNWEHIIQLVRVIEEyd---geLPY-LLEARGKTPPEDVGGVGGFV 326
WP_014269791            257 ES---------HVLLKDV-F-PEKKsCTYLYDFGDSWQHEIIFEREITGstl-----hatLLEMIGQAPPEDSGGPYGYE 320 Spha...
BAK15243                268 ER---------FVSLAEI-F-SQHSeVIYEYDFGDSWEHIITLEKSITAtsq-----qakLIEGKGERPPEDVGGLHGFN 331
CDC60545                174 EGdiedakdstQVKLCKM-GlAVDEqFEMEYGYGCSQMFRIRLDAVSDMergrgshYPY-VIDGQGRGILEDVPAE---- 247
CDB30793                 99 AS---------TYKMRSIlQgCQGEkLTLEYDYGDGWEVEITLESVLEDkelpgreLPR-VLAGEGYGIIEDCGGTGGLE 168

2I1S_A                  152 EMLEVL-KDSE---H-----EEYED-TVLWLGDD-----FD 177
WP_013688615            143 -------QDDAffgD-----EEDED-MNEFD--EdfgdgYD 168 Fluviicola taffensis
jgi:Clopa_3812          318 EFIEIM-SNPI---H-----EEYEH-MKQWADSQdy-ggFD 347
jgi:Hprae_1152          339 EFMRII-SNPD---D-----EEYES-MVEWAESQrf-eeYN 368
Q8G640                  162 RFLDTL-GNPE---D-----EEHDG-MVEWAed----qmWD 188 Bifidobacterium longum
goetting:EAL2_808p02250 327 SFRDIM-LNPE---H-----PEYAE-MKEWSr------yWT 351
WP_014269791            321 QNLACL-KDRE---D-----PAYEE-TLQWVtwRtgyryFy 351 Sphaerochaeta pleomorpha
BAK15243                332 EYLAMI-NDPN---------SAEDEdFMGWAa-SqkertFS 361
CDC60545                248 EFGAIV-AKTDaagKsdyriERYGEne-----------iWD 276
CDB30793                169 QLAAAFrQKSG---------DDYEN-YREWLGRd----eSD 195
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