Conserved Protein Domain Family
AKAP28

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pfam14469: AKAP28 
28 kDa A-kinase anchor
28 kDa AKAP (AKAP28) is highly enriched in human airway axonemes. The mRNA for AKAP28 is up-regulated as primary airway cells differentiate and is specifically expressed in tissues containing cilia and/or flagella. Homologs of AKAP28 are present in all animals and in some, including mice the AKAP28-like domain are preceded by another uncharacterized domain
Statistics
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PSSM-Id: 464180
Aligned: 25 rows
Threshold Bit Score: 130.092
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002063512 143 WMRIGEFAYNNVISEIRDFITK-WQLSPDtkCVVLSNMRRHDVPVKGSIYFVDAHFSRPTPRCPNPLAVAKVRFIISVSK 221
XP_003389725  39 IPTGPEINPEECMETIEELIKS-WDLDGS--WLHHTSYTGVRSVGGRAIHSFSVMFSQPSRRKPAPRATASVFFFF-IVE 114
XP_004987911 114 ALTADELNWDSAKLIIETVVEG-WAISDM--WKYHV----AKEAEGAGYVQACVTWSIPMRRRPVPNATAYTMFNLNKT- 185
XP_002763261  75 WMTHGEFTVENGRKQIDKYLST-CIYKKR--WAHTTVFVERRDLIHSFLYIYHVHWSASSAGIPVAQISSGTYFKLKVSK 151
XP_002832093  67 WMTHGEFTVEKGLKQIDEYFSK-CVSKKC--WAHGVEFIERKDLIHSFLYIYYVHWSISTAELPVARISAGTYFTMKVSK 143
XP_003247803 130 LNENGIFDDQVAIANISSYIKQhWNLEKK--YLYTVEKSLIKMFDISS-HGYKAEFSMSTNEYPIPQVTISAFFTVNETH 206
XP_002048913 122 WLKIGEFEYNNVLAVIRDFIGK-WQLSPKtkCVVLTNTRRHDVALKGTIYFVDAHFSRPTQRCPNPLAVAKVRFIITVSS 200
XP_001995343 121 WQTIDQFEYGNVVAMIRHYIGL-WQVSPQtkCVVLSNRRGREVALKGQIYFVDAHFSRPSQTCTNPLAVAKVRFIITVSR 199
EDX06255      48 MLTIGDFEYSNAIADIRDFVSR-WELSPDtkCVVISNPIRHEVAQKGTILFVDAHFSRPTPRCPNPLAVAKVRFIISVSK 126
3_pfamImport   1 WPKICDFDVFMGQACIERYLSL-LRWSPK--WTNGISLYEIRERGFSTFYIYEVTWGVLRKNAPVNQYCLFTYFMFELCH 77 
XP_002063512 222 VMQKHYPVMITYRFEGFNTLYYAigeratNSWTFQRFHIDTILHSKLHFY 271
XP_003389725 115 GEGTETSTTVFYVVESQRVVLRP-------STPFREVWLRKIISSKLEIN 157
XP_004987911 186 ----EHGISVEWQLEQQRLKHDA------TQP-CREQWLHDVVASKRIVH 224
XP_002763261 152 TKPLDAPIDVSFVGEEQELVHRP------GMVCFREHWQKNLTDAKYDFM 195
XP_002832093 144 TKPPDAPIVVSYVGDHQALVHRP------GMVRFRENWQKNLTDAKYSFM 187
XP_003247803 207 VLSLPA-VYIKYQLEMDRRVYVV------GRHSFNKKHFERQFKMKRDLY 249
XP_002048913 201 VMQKYYPVMITYRFEGYRTLYYAvgdralTLNTFQRFYIDTILHTKLSFY 250
XP_001995343 200 ILPKHYPVMITYRFEGYRTLYYAlgeravNSNSFQRLYIDTILHSKLSFY 249
EDX06255     127 ILLKHYPVMITYRFEGYNTLYYGlgerclNSFTFQRFYIDTILHTKLTFF 176
3_pfamImport  78 IFPPWARVMVRIFVEGVDRIFRP------YDAKLSEYFIISQIQNKYIYN 121
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