Conserved Protein Domain Family
PLN02900

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PLN02900: PLN02900 
alanyl-tRNA synthetase
Statistics
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PSSM-Id: 215487
Aligned: 29 rows
Threshold Bit Score: 1197.52
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
303282971    5 ESPHNGWPANKIRQTFLDFFESKEHAVVPSSPVVPhDDPTLLFANAGMNQFKSIFLGKA--------DPKGPLAKLKRAT 76  
159476100    1 -------TGAEIREAFLSFYESKGHTRLPSSSLVP-EDPTVLLTIAGMLQFKPVFLGQA-------------PRKVATAT 59  
168000843   28 KPLDPEIKGDAIRKRFLEFYAARGHKVLPSSSLVP-DDPTVLLTIAGMLQFKPIFLGQV-------------PRSYPCAT 93  
30688660    72 DYQSKDVSGDSIRRRFLEFFASRGHKVLPSSSLVP-EDPTVLLTIAGMLQFKPIFLGKV-------------PREVPCAT 137 
225428201  101 KSKDLPTSGDSIRHRFLDFYASRGHKVLPSSSLVP-DDPTVLLTIAGMLQFKPIFLGKV-------------PRQVPRAT 166 
224105089   92 KTKENPVSGDAIRRRFLEFYASRSHKVLPSASLVP-DDPTVLLTIAGMLQFKPIFLGKA-------------PRQVPRAT 157 
242092594   57 TAGAGEWSGDAIRRRFLEFYAARGHKILPSSSLVP-DDPTVLLTIAGMLQFKPIFLGKE-------------PRRVPCAT 122 
297812419   72 DYQSKDVSGDSIRRRFLEFFASRGHKVLPSASLVP-EDPTVLLTIAGMLQFKPIFLGKV-------------PREVPCAT 137 
302823356    3 EHEQPGVSGDAIRRTFLNFFAARGHQLLPGSSLVP-DDPTVLLTIAGMLQFKPIFLGQAttldnvllSRAQVPRRFACAV 81  
302834443   75 PGPLKKMSGAEIREAFLSFFESKGHTRLPSSSLVP-EDPTVLLTIAGMLQFKPVFLGQA-------------PRKVPTAT 140 
303282971   77 DTQKCIRAggkhNDLDDVGKDTYHHTYFEMLGNWSFGDFFKREAIHWAWELLTskEHYGLDESRLYASYFGGDEsqglpp 156 
159476100   60 TTQKCVRT----NDIGNVGVTARHHTFFEMLGNFSFGDYFKEQAIKWAWELST--GVFGLPAERVWVSVYEEDA------ 127 
168000843   94 TTQKVVRT----NDIENVGRTARHHTFFEMLGNFSFGDYFKRQAIAWAWELAT--QEFKLPLERVWVSVFEDDD------ 161 
30688660   138 TAQRCIRT----NDLENVGKTARHHTFFEMLGNFSFGDYFKKEAIKWAWELST--IEFGLPANRVWVSIYEDDD------ 205 
225428201  167 TAQRCIRT----NDVENVGKTSRHHTFFEMLGNFSFGDYFKKEAIKWAWELST--IEYGLPADRLWISVYEDDD------ 234 
224105089  158 TAQKCIRT----NDVENVGRTTRHHTFFEMLGNFSFGDYFKKEAIKWAWELST--KEFGLPADRLWVSVYEDDD------ 225 
242092594  123 TSQKCIRT----NDIENVGRTARHQTFFEMLGNFSFGDYFKKEATAWAWELAT--KEYGLPAERLWISVFEDDN------ 190 
297812419  138 TAQRCIRT----NDLENVGKTARHHTFFEMLGNFSFGDYFKKEAIRWAWELST--IEFGLPANRVWVSIYEDDD------ 205 
302823356   82 TSQKCLRT----NDIENVGRTSRHHTFFEMLGNFSFGDYFKHDAIRWAWELAT--SEYKLPAARVWVSVYKDDD------ 149 
302834443  141 TTQKCVRT----NDIGNVGVTARHHTFFEMLGNFSFGDYFKEQAIRWAWELST--GVFGLPPERVWVSVFEEDG------ 208 
303282971  157 dlEARDIWLEV--LPPNKVLPFGCEDNFWEMGDVGPCGPCSEIHYDRIGGRDAADLVN-ADDPNCLEIWNIVFIQFNREE 233 
159476100  128 --EAEAIWRDVvgVAPERIKRMGAADNFWSSGPTGPCGPCSELYYDFHPERGTQDASL-EDDSRFIEFYNLVFMQLNRCP 204 
168000843  162 --EAFAIWRDEvgVPVERIKRMGAEDNFWSSGATGPCGPCSEMYFDFHPERGTDDA-DlNDDSRFIEFYNLVFMQYNRTD 238 
30688660   206 --EAFEIWKNEvgVSVERIKRMGEADNFWTSGPTGPCGPCSELYYDFYPERGYDEDVDlGDDTRFIEFYNLVFMQYNKTE 283 
225428201  235 --EALAIWTKEvgVPVERIKRMGAEDNFWTSGVTGPCGPCSEIYYDFHPERGYSDV-DlGDDTRFIEFYNLVFMQYNKKD 311 
224105089  226 --EAFEIWHDEvgVPVERIKRMGEEDNFWTSGATGPCGPCSELYYDFHPERGYKNT-DlGDDSRFIEFYNLVFMQYNKMD 302 
242092594  191 --EAFDIWHNEvgVPKERIKRMGAEDNFWTSGATGPCGPCSEIYYDFYPERGSSDA-DlGDDSRFIEFYNLVFMQYNKKD 267 
297812419  206 --EAFEIWKNEvgVPVERIKRMGEADNFWTSGPTGPCGPCSELYYDFYPERGSDDDVDlGDDTRFIEFYNLVFMQYNKTE 283 
302823356  150 --EALAIWRDHvgIPEERIKKLGEEDNFWASGPTGPCGPCSEMYFDFHPERGTDDA-DlGDDTRFLEFYNLVFMQYNRND 226 
302834443  209 --EAEAIWRDVvgVPPERIKRMGAADNFWSSGPTGPCGPCSELYYDFHPERGTEGASL-EDDTRFIEFYNLVFMQLNRKP 285 
303282971  234 GGVLKPLPAKHVDTGMGFERIASILQDKMSNYDTDVFTPIFERIREvtgappYTGLLGAEDEGEKDMAYRVVADHIRTLT 313 
159476100  205 DGSLEPLAAKNIDTGMGLERMAQILQGVSNNYETDLIFPIVAKAAA------IAGVDYASAQPAVKTALKVIGDHTRAVT 278 
168000843  239 DGQLEPLKNKNIDTGLGLERMAQILQQVPNNYETDLIYPIIARAAA------LANVDYQSADDRVKTYLKVIGDHTRAVV 312 
30688660   284 DGLLEPLKQKNIDTGLGLERIAQILQKVPNNYETDLIYPIIAKISE------LANISYDSANDKAKTSLKVIADHMRAVV 357 
225428201  312 DGSLEPLKQMNIDTGLGLERMARILQKVPNNYETDLIYPIIEKASE------LANVSYALADDHAKMNLKVIGDHLRAIV 385 
224105089  303 DGSLEPLKQKNIDTGLGLERLARILQKVPNNYETDLIYPIIEKAAE------LANISYALADDRTKMNLKIIGDHLRAIV 376 
242092594  268 DGSLEPLKQKNIDTGMGLERMARILQKVPNNYETDLIFPIIEKAAS------MAMVSYAKTDDATKTNLKIIGDHMRAVV 341 
297812419  284 DGLLEPLKQKNIDTGLGLERIAQILQKVPNNYETDLIYPIIAKISE------LANISYDSANEKAKTSLKVIADHIRAVV 357 
302823356  227 DGKLELLKQKNIDTGLGLERMARILQKVPNNYETDLIYPIIQRASE------LAGVNYTAADDRTKTYLKVIGDHSRAVV 300 
302834443  286 DGSLEPLAAKNIDTGMGLERMAQILQGVPNNYETDLIFPIVQKAAE------IAAVDYHSASPAVKTALKVIGDHTRAVT 359 
303282971  314 FAIADGAAPGSDGRNYVLRRVLRRAVRFGREK-------LGAEQGFFQKLVAVVVELFGHVFPEIVKHEKRVTDIIADEE 386 
159476100  279 YMLSDGVTPSNTGRGYVLRRLLRRVVMKGRL--------LGIREVFTPAVAEVAVALSAACDPAVQRNAQRIYDELAREE 350 
168000843  313 YLISDGVYPSNIGRGYIVRRLIRRVVRMGRLLgirgdgqGNQEGAFLPTVAEVAVAMSKDVDPNVEQQKIKIYNELKREE 392 
30688660   358 YLISDGVSPSNIGRGYVVRRLIRRAVRKGKSLgingdmnGNLKGAFLPAVAEKVIELSTYIDSDVKLKASRIIEEIRQEE 437 
225428201  386 YLISDGVVPSNIGRGYVARRLIRRAVRTGRLLgikgdgrGNPEGAFLPTIAEKVIELSSQIDPDVKSRAPRILEELKREE 465 
224105089  377 YLISDGVLPSNIGRGYVVRRLIRRAVRTGRLLgv---kgGGEDGVFLPAIAEKVIELSPHIDPDVKARGHSILDELQREE 453 
242092594  342 YLVSDGVIPSNIGRGYVVRRLIRRVVRMGRLIgirgdghGNSEGAFLPSLAEVVISLSTEIDPDVESRRRSILGELQREE 421 
297812419  358 YLISDGVSPSNIGRGYVVRRLIRRAVRKGKSLgineyrnGNLKGAFLPAVAEKVIELSTYIDSDVKLKAPRIIEEIRQEE 437 
302823356  301 YLISDGVTPSNIGRGYIVRRLIRRIVRMGRLLgirgdgeGNSEGTFLPSLAKVVISMSSNVDPDVKQNAGRIFEELEKEE 380 
302834443  360 YMLSDGVTPSNTGRGYVLRRLLRRVVMKGRL--------LGIREVFTPAVAAVAVGLSGPCDPAVQKNAQRIYDELAREE 431 
303282971  387 ESFGRTLLKGIDQFKKIAAKAKed------gGAVVDGAAAFLLWESFGFPIDLTEIMAEENGMTVDTAGFDAAFKEAQEK 460 
159476100  351 SLFATTLERGQKQLDEYLDRAAa-------gGKAIAGPDAFMLYDTFGFPLELTQELAEARGVDVDVSGFEAEMEAQRQR 423 
168000843  393 LRFVQTLEKGEKLLEELLAEALekr---gtdTPCLSGKDVFRLYDTFGFPVEITEEVASERGVTVDLAGFESEMEIQRKQ 469 
30688660   438 LHFKKTLERGEKLLDQKLNDALsiad-ktkdTPYLDGKDAFLLYDTFGFPVEITAEVAEERGVSIDMNGFEVEMENQRRQ 516 
225428201  466 LRFVQTLERGEKLLDEMLANALlnsn-engnGPILSGKDVFLLYDTYGFPVEITTEAAEERGVGIDMNGFEIEMENQRRQ 544 
224105089  454 LRFVQTLERGEKLLDQMLAEALlnaq-ksetLPCLSGKDVFLLYDTFGFPVEITTEVAEEQGVKIDMDGFEVEMENQRRQ 532 
242092594  422 LRFVQTLERGEKLLDELLDGAVlsag-nngdKPSLSGKDLFLLYDTYGFPVEITAEIASERGVTVDIEGFDIEMENQRKQ 500 
297812419  438 LHFKKTLERGEKLLDQKLNDALsiad-ktknTPYLDGKDAFLLYDTYGFPVEITAEVAEERGVSIDMKGFEVEMENQRRQ 516 
302823356  381 LRFVQTLERGEKLLSQKLEEAAaacrrdgstKPVLSGKDVFMLYDTYGFPVEITEEVAGENDVQVDMAGFETEMEYQRRQ 460 
302834443  432 GLFVATLERGQKQLDELLSAATas-----tgSRVIGGADAFMLYDTFGFPLELTQELAEARGVEVDVAGFDGEMEAQRQR 506 
303282971  461 SRAGG----KKSDGPSLLFEAEATSWLQKNGskwgkakdiahahdaIPFTDDSPKYDGPEadPSAVVKAILTLNGFVEST 536 
159476100  424 SKDSRetldLTAQAGLAALAA-------------------------AVGPTAFTGYSATR--GAGRVRGLMRGGAPVEVV 476 
168000843  470 SQAAHnvikLAVGGAAQEMLA-------------------------QVPETEFLGYDDLT--SSSSILAILANGEALGEA 522 
30688660   517 SQAAH---------NVVKLTVEDDADMTK-----------------NIADTEFLGYDSLS--ARAVVKSLLVNGKPVIRV 568 
225428201  545 SQAAH---------NAVKLAVGNSADLTE-----------------NISDTEFLGYETLS--TKAVIEGLLVNGNPVIQV 596 
224105089  533 SQAAH---------NVVKLAVENGGDLAE-----------------NVHDTEFLGYDTLS--ARAVVESLLLNGKSVIQV 584 
242092594  501 SQAAHnvvkLSVGNETEIIK--------------------------SIPDTVFLGYDSLS--ASAVVRGLLVNGNPVNEV 552 
297812419  517 SQAAH---------NVVKLTVEDDADITK-----------------NIADTEFLGYDSLS--ARAVVKSLLVDGKPVIKV 568 
302823356  461 SQEAHnvvkLSAGGTAAELT--------------------------SLVETKFVGYTTLE--SIAEVRALIARGGLVTEV 512 
302834443  507 SKESRetvdLTAQAGLAQLAAQTHSRSWLPPgvripi----rtqrmRVGPTSFTGYSATR--GCGRVVGLMREGKPVERV 580 
303282971  537 EGVEgpIGLVLDRTSFYAESGGQVCDVGVITTENGa------S-LAVNEVKVA--AGFVLHSGERVEGeAITVGNTCAAR 607 
159476100  477 EAGDr-CEVLLDSTPFYAESGGQVGDMGVLTAHGSgea--aaE-LSVSDCQKAagGSVFVHTCEVKAG-QLRVGDQVTAL 551 
168000843  523 SEGEe-VELLLDRTPFYAESGGQVGDHGYLRVFGGds---eaV-VKVKDVVKE--AGRFRHIGVVQDG-IVKVGLGVEAE 594 
30688660   569 SEGSe-VEVLLDRTPFYAESGGQIADHGFLYVSSDgnq-ekaV-VEVSDVQKS--LKIFVHKGTVKSG-ALEVGKEVEAA 642 
225428201  597 SEGSd-VEIFLNRTPFYAESGGQIGDHGFLYVNEDrnq-knaV-VEIKDVQKSl-GNIFVHKGTIKEG-VVEVGKEVEAA 671 
224105089  585 SEGSe-VEVLLNKTPFYAESGGQIGDHGFLYVTQDqsk-qtaV-VEIKDVQKSl-GSVFVHKGTIREG-VLEVGREVEAA 659 
242092594  553 SEGSe-VEILLDRTPFYAESGGQVGDNGFLYVNGGedrsqaaV-IEINDVQKSl-GNIFVHKGTIKQG-SVEVGKEVDAC 628 
297812419  569 SEGSk-VEILLDRTPFYAESGGQIADHGFLYVNSDgnq-enaV-VEVSDVQKS--LKIFVHKGTVKSG-ALEVGKEVEAA 642 
302823356  513 REGDe-VEIVLDTTPFYAESGGQIGDNGLLVCRGGet---dcI-VQVKDVQKLg-SNLIIHKGIVQQG-TMAVGNNVQAL 585 
302834443  581 HAGDr-CEVLLDVTPFYAESGGQVGDMGRLVLPAAageaevaAeVAVRDCQKAagGSVFVHSCEVVAG-ELGVGDAVNAL 658 
303282971  608 VDYDRRANIAPNHTMTHVLNFALRSVLGDGVDQKGSLVDDEKLRFDFSHNKPMSNNEIKRVEEIVRERVGASLAVDAREV 687 
159476100  552 VDEDLRRRVRAHHTATHLLQSALKAVLGPDTCQQGSLCNFQRLRFDFNLARGMTAAEVAEVERLVNGWVAAAAPLETRVM 631 
168000843  595 VDPVLRTRAQIHHTATHLLQAALKNVLGSDVSQAGSLVSFDRLRFDFNLPRAMTDAEINKVEMLVNEWIGMGVPVTSEEM 674 
30688660   643 VDADLRQRAKVHHTATHLLQSALKKVVGQETSQAGSLVAFDRLRFDFNFNRSLHDNELEEIECLINRWIGDATRLETKVL 722 
225428201  672 VDANLRQRAKIHHTATHLLQAALKKVIGDETSQAGSLVAFDRLRFDFNFHRPLQEKELVEIEELINGWIGDATLLQTKVM 751 
224105089  660 VDAKLRQRAKVHHTATHLLQSALKKVIGQETSQAGSLVAFDRLRFDFNFHRPLHDSELEEIENLINGWIGDGTLLQTKVM 739 
242092594  629 VDAKLRQGAKAHHTATHLLQSALKSVVGSETSQAGSLVAFDRLRFDFNFHRPVSEGELTRIELLVNQWISNAAHLETKVM 708 
297812419  643 VDADLRQRAKVHHTATHLLQSALKKVVGQETSQAGSLVAFDRLRFDFNINRSLHDNELKEIERLINRWIGDATRLETKVL 722 
302823356  586 VESSLRRRAQAQHTATHLLQAALKKVLGSETSQAGSLVAFDRLRFDFTLSRKMAEEEVVQVEALVNEWISMAVPLEWKVM 665 
302834443  659 VDDDLRRRVRAHHTATHLLQSALKIVLGPDTCQQGSLVNFQRLRFDFNLARAMSPSELTEVERLVNCWVAQAAPLETRVM 738 
303282971  688 ALADAKTiSGLRAVFGEVYPD-PVRVVSVGPTidellanpgseewtkySIEFCGGTHLANTSQAEGFVLLEEAGIAKGIR 766 
159476100  632 DLAAAKA-AGATAMFGEKYDD-TVRVVDVPGI----------------SMELCGGTHVANTAEIGAFKILSESGIASGIR 693 
168000843  675 AIAAAKE-KGAIAMFGEKYGE-QVRVISVPGI----------------SMELCGGTHVRNIAEIRGLKIMSEQGIASGVR 736 
30688660   723 PLADAKR-AGAIAMFGEKYDEnEVRVVEVPGV----------------SMELCGGTHVGNTAEIRAFKIISEQGIASGIR 785 
225428201  752 PLADAKR-AGAIAMFGEKYGE-QVRVVEVPGV----------------SMELCGGTHVSNTCEIRGFKIISEQGIASGIR 813 
224105089  740 SLTDAKE-AGAIAMFGEKYGE-QVRVVEVPGV----------------SMELCGGTHVSNTSEIRAFKIISEQGIASGIR 801 
242092594  709 ALQDAKN-AGAIAMFGEKYGE-QVRVVEVPGV----------------SLELCGGTHVSNTAEIRGFKIISEQGIASGIR 770 
297812419  723 PLADAKR-AGAIAMFGEKYDEnEVRVVEVPGV----------------SMELCGGTHVGNTAEIRAFKIISEQGIASGIR 785 
302823356  666 PLAEAKN-SGAIAMFGEKYGE-QVRVVDVPGI----------------SKELCGGTHVSNTSEIRGFKIVLVEGIASGVK 727 
302834443  739 GLQEAKA-AGATAMFGEKYDD-VVRVVDVPGI----------------SMELCGGTHVGNTAEIGAFKILSESGIASGIR 800 
303282971  767 RVVAATRGGAVAALATAAGIAARVDACDAMppgpeldkemaalkndvdtavmpavQRAEIRDRMAATTKKLIAAAKEAAV 846 
159476100  694 RVEAVAGPAAVEYLNQVDGLVRGLSGQLKL-------------------------KPEEVPARVSAMQAELREAAKQLAD 748 
168000843  737 RIEAVAGNAFIEYINARDAVVKQLSASLKV-------------------------KADDLAGRVVGLQEEVRASRNEAAA 791 
30688660   786 RIEAVAGEAFIEYINSRDSQMTRLCSTLKV-------------------------KAEDVTNRVENLLEELRAARKEASD 840 
225428201  814 RIEAVAGDAFIEYVNARDNHMRQLCSTLKV-------------------------KAEEVTTRVEALLEELRMTRNEVSA 868 
224105089  802 RIEAVAGEAFIEYINARDSQMKLLCSTLKV-------------------------KAEEVTTRVDNLLEELRTVRNEVSA 856 
242092594  771 RIEAVAGDAFIDYVCARDNYMRRLCSSLKV-------------------------KAEDVNGRVETILEELRATRNEVSS 825 
297812419  786 RIEAVAGEAFIEYINSRDSQMTRLCSTLKV-------------------------KAEKVIETVENLLKELRAAKKEASD 840 
302823356  728 RIEAVAGNAFIDHIFARENALRQICSSLKA-------------------------KPEDLPARISGLQDELKALKSEATS 782 
302834443  801 RVEAVAGTAAVEYLHTVDGLVRGLAGQLKV-------------------------KLEEVPSRVAALQSELRSTEKLLSE 855 
303282971  847 AVKAAAKKAVEEKTAEVKAAGET----VFVMRLGDGADPGALKDAAAVAFKQ--DVACALFSADT-VKGKAMCYVSAPPS 919 
159476100  749 LKAQLAVAQSQALVSQAVTAPQGg--kVLVAELAGGVEAKALQEAAVKLQEAlgDPAAVVLASR--VDDKVNFVAAFSAG 824 
168000843  792 LRVELAVAKAEALLSTATSIGDSst-rVLVASLDK-IDAESLKAAAEHLLAKlgDPAAVVVGSSP-GDGKVSLVATFSPS 868 
30688660   841 LRSKAAVYKASVISNKAFTVGTSqtirVLVESMDD-TDADSLKSAAEHLISTleDPVAVVLGSSP-EKDKVSLVAAFSPG 918 
225428201  869 VRAKAAVYKASVMAGNAFPVGTSkkirVLVESMDD-IDADSLKSAAEYLIDTlqDPAAVILGSCP-SEEKVSLVAAFTPG 946 
224105089  857 LRAKAAVYKASMIASKAFSVGTSktirVLVESMDD-FDADALKSAAEYLMDTlqDPAAIILGSCP-DEGKVSLVAAFTPG 934 
242092594  826 LRSKIAVLKAASLASKATTVEPQnv-rIVVENMGD-VDADGLKSAAEYLIGTlqDPAAVILGSSP-GDGKVSLVAAFSPA 902 
297812419  841 LRSKAAVYKASVISKNAFTVGTSqtirVLVDSMDD-TDADSLKSAAEHLISTleDPVAVVLGSSP-EKDKVSLVAAFSPG 918 
302823356  783 LRAKVAIAEADVLTGRALLVGPGgv-rILVGALET-TDVDSLRAAVEHCVALhgDPSATLLGACT-EDGKVSLVAAFSPS 859 
302834443  856 LKAQLAVAQSQSLVGEAVTAPGGl--kVLVAELPGEVEAKAMQGALg-------DPAAVLLASRAvDGSKVNFVAALSPG 926 
303282971  920 AT-PAIDVKKWLdACCGPIEGKGGGGKGGVAQGQGNKVEGLDDAI 963 
159476100  825 AVkAGVQAGKLV-GAVAKVCGGGGGGKPALAQAGGKDASKTSEAL 868 
168000843  869 VVkQGIQAGKFV-GTIAKICGGGGGGRPNFAQAGGRQPEKLDEAL 912 
30688660   919 VVsLGVQAGKFI-GPIAKLCGGGGGGKPNFAQAGGRKPENLPSAL 962 
225428201  947 VVdLGIQAGKFI-GPIAKLCGGGGGGRPNFAQAGGRKPENLSGAL 990 
224105089  935 VVdIGIQAGKFI-GPIAKLCGGGGGGRPNFAQAGGRKPENLTNAL 978 
242092594  903 VVkMGLQAGKFV-GGIAKLCGGGGGGKPNFAQAGGRKPENLPDAL 946 
297812419  919 VVsLGVQAGKFI-GPIAKLCGGGGGGKPNFAQAGGRKPENLPSAL 962 
302823356  860 VVkHGLKAGAFV-GSVAKLCGGGGGGRPDFAQAGGKLPDKLPGAI 903 
302834443  927 AVkGGLQAGKVV-GAVAKVCGGGGGGKPALAQAGGRDASKTEEAL 970 
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