15640810 10 HTKVCQTLSFQQRVGALLVAMVVIQLSLVAGFFHQTLSETLQDQISTKALIQAREIATDPNLIVLIQQNRL--------- 80 Vibrio cholerae 21362444 1 MKRRLFPLTFSAKMMGFIALLIIAMFVLLGVFLNEQYARTLEEQMGERALSVAQAVALIPELREAFSAERPd-------- 72 Bacillus halodurans 21362406 1 MVKKRFHFSLQTKIMGLIAALLVFVIGVLTITLAVQHTQGERRQAEQLAVQTARTISYMPPVKELIERKDGh-------- 72 Bacillus subtilis 19551318 10 NFKEVDIIRFATRILVIQVATVALVVAICTGIFAVLMMDQMKTEAEHTALSIGRSVASNPQIREEVALDTQtganpsaee 89 Corynebacterium glu... 15829912 9 QFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTASFEDYLTLHVRDMAMNQAKIIASNDSVISEVKTRDY--------- 79 Escherichia coli O1... 15675090 1 ---MKKPLRLWASLSLILVSMIVVTTSLFYGIMLHDTHQSIKNQETHLLTSTGKMLASHQAIKELLLNNQPn-------- 69 Streptococcus pyoge... 16763443 6 ITRWFARHSFQNRIFLLILFTSTIVMLAITWYLTDITKERLHYQVGQRALIQAMQISAMPELVEAVEAHDL--------- 76 Salmonella typhimur... 16764002 9 LFPFFRQLAFPLRIFLLILVVSVFIVAALAQYLSASFEDYLASHVRDMAMNQAKIIASNDSIIAAVKNRDY--------- 79 Salmonella typhimur... 15800334 9 QFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTASFEDYLTLHVRDMAMNQAKIIASNDSVISEVKTRDY--------- 79 Escherichia coli O1... 2500761 9 QFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTASFEDYLTLHVRDMAMNQAKIIASNDSVISAVKTRDY--------- 79 Escherichia coli
15640810 81 ---AEVQAKIDRLQRISDANFIVIGDANG-IRIAHPDEQKIGLPMQGGDsRRALKEGEYYTSTQKGSLGWAIRGKAAIVA 156 Vibrio cholerae 21362444 73 ---EIIQPIAESIRVETGAEFIVVGNTDL-IRYAHPLPERIGQRMVGGDnERALVHGESYVSKAVGSLGPSIRGKVPVFD 148 Bacillus halodurans 21362406 73 --aAQTQEVIEQMKEQTGAFAIYVLNEKGdIRSAS--G-KSGLKKLERS--REILFGGSHVSETKADGRRVIRGSAPIIK 145 Bacillus subtilis 19551318 90 ladGDIQAVAQAANERTGALFVVITDGLG-IRLSHPDEERLGEQVSTSF--EAAMRGEETMAWETGTLGASARAKVPIFA 166 Corynebacterium glu... 15829912 80 ---KRLATIANKLQRDTDFDYVVIGDRHS-IRLYHPNPEKIGYPMQFTK-QGALEKGESYFITGKGSMGMAMRAKTPIFD 154 Escherichia coli O1... 15675090 70 ---AKTTAYTNSIASIYNLDYVVVMNMKG-IRLTHPNPKNIGKPFQGGD-EEAVLAGKKVISTAKGTLGKSLRYLVPVFD 144 Streptococcus pyoge... 16763443 77 ---SRIKALIDPMRSFSDATYITVGNEKG-QRLYHVNPDEIGKYMEGGDsDDALYNAKSYVSVRKGSLGSSLRGKSPIQD 152 Salmonella typhimur... 16764002 80 ---KRLAIIANKLQRGTDFDYVVIGDRHS-IRLYHPNPEKIGYPMQFTK-PGALERGESYFITGKGSIGMAMRAKTPIFD 154 Salmonella typhimur... 15800334 80 ---KRLATIANKLQRDTDFDYVVIGDRHS-IRLYHPNPEKIGYPMQFTK-QGALEKGESYFITGKGSMGMAMRAKTPIFD 154 Escherichia coli O1... 2500761 80 ---KRLATIANKLQRDTDFDYVVIGDRHS-IRLYHPNPEKIGYPMQFTK-QGALEKGESYFITGKGSMGMAMRAKTPIFD 154 Escherichia coli
15640810 157 PS---GEILGVVSVGYLLDNISSWLRVYSYPVIFTVLLLMLLSALGAWIFTRHIKQQMFNMEPEEIAMNLNLQQSILQSV 233 Vibrio cholerae 21362444 149 DN---GKIIGIVSVGFLMEDIQQVIGERLIAMWQIVVVIMILGLMGTWLVANTVKKATLGLEPEEIGQQFQQKEAILQSI 225 Bacillus halodurans 21362406 146 EQkgySQVIGSVSVDFLQTETEQSIKKHLRNLSVIAVLVLLLGFIGAAVLAKSIRKDTLGLEPHEIAALYRERNAMLFAI 225 Bacillus subtilis 19551318 167 PDs--SVPVGEVSVGFERDSVYSRLPMFLAALALISVLGILIGVGVAMGMRRRWERVTLGLQPEELVTLVQNQTAVIDGI 244 Corynebacterium glu... 15829912 155 DD---GKVIGVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIARVVRQQEALFSSV 231 Escherichia coli O1... 15675090 145 GD----KQIGAIAVGIKLTTLNDVALTSKRNYTLSLLLCLLISLLVTSFISFRLKRQLHQLEPSEIYQLFEERNAMLDQI 220 Streptococcus pyoge... 16763443 153 ST---GKVIGIVSVGYTLEQLESWLNLQISSLLFPMALLLLVLLYCARRFSLHIKKQMLNMEPQQLSQLLIQQSVLFESV 229 Salmonella typhimur... 16764002 155 NE---GNVIGVVSIGYLVSKIDSWRLDFLLPMAGVFVLLLVVLMLLSWFFAAHIRRQMLGMEPKQIARVVRQQEALFSSV 231 Salmonella typhimur... 15800334 155 DD---GKVIGVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIARVVRQQEALFSSV 231 Escherichia coli O1... 2500761 155 DD---GKVIGVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIARVVRQQEALFSSV 231 Escherichia coli
15640810 234 YEGIVAISLKGEILSVNAKALNILGIAHQPTHLIGRNVQEFITPtCFFMGASpfgklaQQNRVSQQDELISCNGETLVAN 313 Vibrio cholerae 21362444 226 HEGVIAVNKEGKVTLFNQAAMKYVDPELDKEDVLGRHVTDLVK--HTRLPEV------LQVGKGQYDQELRIGDKQAVVN 297 Bacillus halodurans 21362406 226 REGIIATNREGVVTMMNVSAAEMLKLPEP---VIHLPIDDVMP--GAGLMSV------LEKGEMLPNQEVSVNDQVFIIN 294 Bacillus subtilis 19551318 245 DEGVLALSPNGTIGVHNEQAQSMIGAGPMS----GRTLKELGL--DLGLDGV--------VLHGQHPETVAHNGRILYLD 310 Corynebacterium glu... 15829912 232 YEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIAEVVRPaDFFTEQI------DEKRQDVVANFN---GLSVIAN 302 Escherichia coli O1... 15675090 221 EAAVFVVDKAGILQLCNQAGQKLIARKCQLGKPTGNSFNYLFP----DFPKL--------SLQEGHEQLFRYGEEDYLLA 288 Streptococcus pyoge... 16763443 230 FEGLIAIDSHHRITAINQTARRLLNLSQPESELIGYAIHHVVLPeAFFYDAP------QKNKKDEIVTFN---QMKVIAS 300 Salmonella typhimur... 16764002 232 YEGLIAVDPEGHITAINRNARKMLGLPSPGRQWLGKLIAEVVNPaDFFTCQI------AERRQDVMANFN---GLSVIAN 302 Salmonella typhimur... 15800334 232 YEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIAEVVRPaDFFTEQI------DEKRQDVVANFN---GLSVIAN 302 Escherichia coli O1... 2500761 232 YEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIVEVVRPaDFFTEQI------DEKRQDVVANFN---GLSVIAN 302 Escherichia coli
15640810 314 RVPINSGQQQIGWVVSFRRRNDFNTLTSQLTQIRQHNDNLRVMSHEFANRLSTIGGLIQIGAYDEAVKTIRRET-AEQQQ 392 Vibrio cholerae 21362444 298 RVPIYYDHEIVGAVATFRDRNEIKKLSEELTNVKNYADALRAQTHEFSNKLNTISGFLQLGKIDEAVDFIQKER-KIQQE 376 Bacillus halodurans 21362406 295 TKVMNQGGQAYGIVVSFREKTELKKLIDTLTEVRKYSEDLRAQTHEFSNKLYAILGLLELGEYDEAIDLIKEEY-AIQNE 373 Bacillus subtilis 19551318 311 FHPVRRGDQDLGYVVTIRDRTDIIELSERLDSVRTMTHALRAQRHEFANRIHTATGLIDAGRVHDAAEFLGDISrNGGQS 390 Corynebacterium glu... 15829912 303 REAIRSGDDLLGAIISFRSKDEISTLNAQLTQIKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGES-QAQQQ 381 Escherichia coli O1... 15675090 289 ISPICVKNDHRGHIIFMREAVKAIDTLDQLAYTTAYASALQAQTHKFMNQLHVIYGLVDIAYYDQLKIYLDSIL-EPENE 367 Streptococcus pyoge... 16763443 301 RMAVIIDNQPQGWVISFRNKDDINTLSLQLSQVRQYADNLRAVQHEHRNLISTIAGLLFLKRYDNALALIQQQS-ESHQK 379 Salmonella typhimur... 16764002 303 REAIRSGEELLGAIISFRSKDEIATLNAQLTQIKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVREMVQGES-QAQQQ 381 Salmonella typhimur... 15800334 303 REAIRSGDDLLGAIISFRSKDEISTLNAQLTQIKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGES-QAQQQ 381 Escherichia coli O1... 2500761 303 REAIRSGDDLLGAIISFRSKDEISTLNAQLTQIKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGES-QAQQQ 381 Escherichia coli
15640810 393 LIDFIAQTFHPKVIAGLLLGKYSRAKELGLCLEFDPLSHLHQEPQCMTSDELAAVLGNLLDNAFEATLKnPHSNKTISLL 472 Vibrio cholerae 21362444 377 WIHFFIERVNDPTVSAVLLGKISQAQELGIDVDIDPSSQLLTPLQERQQELLVTMIGNLLENAFDALLAsGIENKKIYIS 456 Bacillus halodurans 21362406 374 QHDLLFHNIHSQQVQAILLGKISKASEKKVKLVIDENSSLAPLPAHIGLSHLITIIGNLIDNAFEAVA--EQSVKEVLFF 451 Bacillus subtilis 19551318 391 HPLIGSAHLNEAFLSSFLSTASISASEKGVSLRINSDTLILG--TVKDPEDVATILGNLINNAIDAAVA-GEAPRWIELT 467 Corynebacterium glu... 15829912 382 LIDSLREAFADRQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLRsDEGNKIVELF 461 Escherichia coli O1... 15675090 368 ILTSLSVLVKEPLLASFLIGEQEKYQELNVHLKIDVLSEIPHSATKNQLNNGLMIYRFIHTNLLTTLR----P-KSLVLS 442 Streptococcus pyoge... 16763443 380 VLDFISHNFRDHHLAGLLIGKYYRAKELGLELIFDPSSFVEHLPSSLSHNEWISIVGNLLDNAYNATLLnREGSRQIECL 459 Salmonella typhimur... 16764002 382 LIDSLRGAFADRQVAGLLFGKVQRARELGLKMVIVPGSQLHQLPEGLDSTEFAAIVGNLLDNAFEASLRtQEGDKTIELF 461 Salmonella typhimur... 15800334 382 LIDSLREAFADRQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLRsDEGNKIVELF 461 Escherichia coli O1... 2500761 382 LIDSLREAFADRQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLRsDEGNKIVELF 461 Escherichia coli
15640810 473 LTDNGAELVIEVADNGIGISADIAQ--TLFLKGVSSKN--QEGHGIGLYLVHQFVTQAHGSILIDSA-EPQGTIFSIFIP 547 Vibrio cholerae 21362444 457 FTDMGDDFIFEVEDNGPGIPPQLME--SIFEEGFSTKEg--THRGFGLALVKKAVHELGGAIFLEEG-ELGGACFVLTIP 531 Bacillus halodurans 21362406 452 ITDMGHDIVIEVSDTGPGVPPEKIE--AVFERGYSSKG---MRRGYGLANVKDSVRELGGWIELANQ-KTGGAVFTVFIP 525 Bacillus subtilis 19551318 468 LMDDADTLVISVADSGPGIPEGVDVfaTATQIGDSEDNerTHGHGIGLKLCRALARSHGGDVWVIDRgTEDGAVFGVKLP 547 Corynebacterium glu... 15829912 462 LSDEGDDVVIEVADQGCGVPESLRD--KIFEQGVSTRAdePGEHGIGLYLIASYVTRCGGVITLEDN-DPCGTLFSIYIP 538 Escherichia coli O1... 15675090 443 IQHDQNHLISHYTLTDNWIDLERVQ--PIFDLPYFQQL---LTDTNSQFHQHQTVTELQFSVTTPYV-GGQHERFNH--- 513 Streptococcus pyoge... 16763443 460 INSEGNEVIIEVADQGCGIDENIRQ--HIFERGVTTHN--NGDHGIGLWLVHSYVKQANGDIIVDNN-NPFGTIFTLYIP 534 Salmonella typhimur... 16764002 462 LSDEGDEVVIEVADQGCGVPEALRE--KIFEQGVSTRTdePGEHGIGLYLIASYVGRCGGVITLEDN-DPCGTLFSLFLP 538 Salmonella typhimur... 15800334 462 LSDEGDDVVIEVADQGCGVPESLRD--KIFEQGVSTRAdePGEHGIGLYLIASYVTRCGGVITLEDN-DPCGTLFSIYIP 538 Escherichia coli O1... 2500761 462 LSDEGDDVVIEVADQGCGVPESLRD--KIFEQGVSTRAdePGEHGIGLYLIASYVTRCGGVITLEDN-DPCGTLFSIYIP 538 Escherichia coli
15640810 548 NRPKTLA 554 Vibrio cholerae 21362444 532 KHEAKEG 538 Bacillus halodurans 21362406 526 KEKQRGN 532 Bacillus subtilis 19551318 548 GVME--- 551 Corynebacterium glutamicum ATCC 13032 15829912 539 KVKPNDS 545 Escherichia coli O157:H7 15675090 ------- Streptococcus pyogenes M1 GAS 16763443 535 FTREE-- 539 Salmonella typhimurium LT2 16764002 539 KVKKNDD 545 Salmonella typhimurium LT2 15800334 539 KVKPNDS 545 Escherichia coli O157:H7 EDL933 2500761 539 KVKPNDS 545 Escherichia coli
Jiyao W et al.(2023). "The conserved domain database in 2023.",