5HWS,1YJQ,3HN2,3GHY,3I83,5ZIK


Conserved Protein Domain Family
PanE

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COG1893: PanE 
Ketopantoate reductase [Coenzyme transport and metabolism]
Ketopantoate reductase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis
Statistics
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PSSM-Id: 441497
Aligned: 882 rows
Threshold Bit Score: 47.5439
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5HWS_A         1 MRIYVLGAGSIGSLFGALLARAgndVTLIGR-REQv-----DAI-NK-NG-LHV-FGaeef---tvkPK-ATIY-APe-E 64 
WP_129886584   1 MKILVYGAGVQASYLAHVLIRGgndVTVLAR-GKRs-----EEL-QK-DG-IVI-RHylqckttvdsVN-VIST-LEpdD 68 
WP_008780899   1 MKIAILGAGNAGCAVAADLTLKgheVTLI-KtSHAmhddnfEYMqSH-KGeMTLnEFgkvs---tayIHrVTRD-LEelQ 74 
WP_014569110   1 MKVTIIGAGNTGFACASDLKRRgieTTIFSR-DPVk----aAKL-TK-CS-FTI-TGritt---ttqFR-VSANlAAsvN 67 
NP_348099      1 MKILIYGAGVLGSYAAYELKRVgheVTILAR-SSRy-----EEL-KE-KG-LVI-RHwfqrkttknkIN-VVKE-LLpeE 68 
WP_058257816   1 MNISVLGAGNGGTAVAADLSLRghdVTLI-KtSHAlhdqnfEYLiKN-EGtVKLiENgetk---vakIKqITRD-LSklS 74 
WP_011809288   1 MKVSILGAGGVAFGTAAFLARAghdPMLWSP-SGKg----tEPF-EAgAP-LVA-QGaiel---eflPR-VAKDcAQavH 68 
WP_013251149   1 MDVLVVGIGVIGSYLAHAACDAgnaVTVVAR-GRWg-----DTI-RD-RG-LVI-HHhvqhkttidhPY-VVDG-IPqgE 68 
WP_106447347  13 RRVAILGAGGIAFGYAAFLRQQgheVTLWSP-SGHg----tAAL-ANgAD-LRA-SGavvg---gwkVR-VASTcAEalS 80 
WP_005927504   1 MKILVYGAGVLGCNLARNLLRAgkdVTLLAR-GNWa-----AEI-KQ-NG-LRI-KDkfslrtsvsrIP-VVTE-LApdA 68 
5HWS_A        65 PpDLLILAVKSYSTKTALEAARQCIGRNTw-V-LSIQNGLGNEELALKYTP-------N--V-M----GGVtTNGAMLvE 128
WP_129886584  69 VyDLIFVSMMYSDFPAVLPILAHNQSRH---I-VLVGNNANAES-MQQYLKensatekK--V-I----FGFqTNGGRRe- 135
WP_008780899  75 DaEIVIIYIQTNYHEQLIEKIAPYLQKDQ--I-LLINPGYLSTAYVLKYCQd-----kP--IiVaeaqSSFi--DGRVmE 142
WP_014569110  68 FaDIIIIATWANAHEDIISAIKPFIHQDQtiI-F-LNGNWGMLQ-AVAKLTpdw--iiQkhV-Si---LETsGMPYVAqW 138
NP_348099     69 YyDAVFIVMQSSQTNAILPVITANVKCP---LfVFVGNQDKA-KDISEKIKstsksnpR--V-L----FGFfSIGGRR-E 136
WP_058257816  75 EsEVVIIYIQTNYHENLIKRIKPYLKDGQ--V-LLINPGYLSTTYVLRHCKd-----iD--LtIceaqSSFi--DCRInE 142
WP_011809288  69 GaEVLLICLPGFCHKTTMDAVAPHIRDGQtvI-ISSHISLGALY-LSQLLAar---giRatI-Ia---WGTtLITGTRnA 139
WP_013251149  69 RfDVAFSVMRQDQQIAALDQLEGIDAD-L--L-VLVGNNLRA-QELADRLRshg-harR--V-L----FGFqSTAGIR-K 134
WP_106447347  81 SaQLVIVALPAYGHRTVIDAMAPHVENGQvvV-FSAHLSLAAQV-LRRALSar---gvAapV-Aa---LGTtVLTARKsE 151
WP_005927504  69 MyDVIFVVLRYTQLDSVLDTLRANRTKN---I-VFVGNNVQTKA-LAAALPe-----kN--V-L----FAFaLSAGHRe- 130
5HWS_A       129 WG-KVLwa--gkG----ITVIGry-----pT--GrD-D-FvDEV-ASVFNEAGIDt-SVtENAIGWKWAKAIVNSVINGL 190
WP_129886584 136 NG-RVInirfgsG----HMDLGtl-----dG--Dr--SwR-PLL-ERAFVHTSYKl-GFaENIDAWLKSHMVLILALHGV 198
WP_008780899 143 PG-QFK--------------VGfrnvrnpiGiyP-S-S-RkEEa-IEKLDKLQERfvYL-DSVVEAALHNPNLVVH--TV 200
WP_014569110 139 HNhSLHi-----SeiktKVTVAay-----gN--QqAwR-KgLNLlKQLY---SEIsvS--PSVLQTSLSAL--NPIIHVP 198
NP_348099    137 GG-KVIsvhtkhP----DFDIGdl-----eG--Rd--DyK-III-EKIFKETSFKl-HYhVNMDDFFKTHIVVIMPLAYL 199
WP_058257816 143 PG-TIK--------------VGfrnvrnplGiyP-K-K-HlEYg-KEKLDHLGFPfvYL-PSVIEAGLHNPNLIIH--TV 200
WP_011809288 140 TCaNVVtv-------rgKMDVAtv-----pE--RdA-D-RaVELcTRLF---GDRfvQR-DGLLAIALSNL--NPQNHLA 197
WP_013251149 135 AD-HVEcvrwgaT----GLDVApl-----hG--EpTaSdK-NLL-ARVFT-GGYRp-NWtHDFEDWLLYHAAAVLPMCFV 198
WP_106447347 152 PD-AVRi-----GtvrqKVDIAvl-----pV--EaT-G-DvVAQcCDLF---GDRfeAT-PDLLSVALANL--NPQNHLA 210
WP_005927504 131 VD-RVVsi--dlK----KITIGql-----pG--AiS-N-K-QLI-GRIFHGTKYKv-VYePNMEDYLLCHAAFVMPAAFA 191
5HWS_A       191 GTVLEVKNg------------HLKdd-pHLEGISVDIAREGCMVAQQLGiefEiH---------P-LEll-----wdT-I 241
WP_129886584 199 MSAYEGNLg------------KAAsd-kKRLNQVIAALDEGHRILETLGypiIpAaqaql-vrrrpLVylf---lkiFtV 261
WP_008780899 201 GSVMSIPRiekshgdfcmyheAYTrdnpATWRILEAMDAEKMNVLEKLGfsr-----------lsyVEacky--rnsLdd 267
WP_014569110 199 VSLFNLPRiehaer-fhiltdGLSe---STRAYIMRIDTERKQLASVLDipySs-----------iVHqlat--qwgTdf 261
NP_348099    200 AYMSNCDLr------------KIAwn-rKALNAVIDAMIEGHEVLIKLGhkvDpEsserllrnhRkVAylg---lkvCaM 263
WP_058257816 201 GAIMSIPRiektkgeycmyheVFTp---SVWNILEALDKEKMDVMEKMGcer-----------lpyVEackf--rntLdd 264
WP_011809288 198 IALMNLTRmerget--wgqaeNVTp---AVGRLIEALDLERLAIAAALGvkvKt-----------vREhfsl--sfhVpa 259
WP_013251149 199 SYLCGCDLr--------------Aas-hELLRQMVAAQGEGYALLARLGhpvApEgnegl--ldggLKtrmwlavvwIvA 261
WP_106447347 211 IALCNLTRmelget--wrqasHITp---AVCRLIEALDAERLALAAAFGiqvRt-----------vHQhihl--sygVsi 272
WP_005927504 192 CYKTDGDLk------------KLRgd-tAYLNRVLDANIEGYRAIRDAGhtilpKedad--fegEkYRktclrffklMcA 256
5HWS_A       242 ertrenyNST----LQd-iWRGR-----ETEVDYIh---------GKIVEY--ARSV-GMEAPRNELLWVLv-Ka-K--- 294
WP_129886584 262 -------TPIasiiYKq-pTPAQl-----AEYRALy---------HDFASL--KQKA-SLATPNWDALTRHipEs----- 311
WP_008780899 268 n---kdaKEVfl-dYAemdTRAKg----PTQVDSRyise--dvpqGLVMLEalGKSL-DVATPIVSSLIEIa-SaaLgrd 335
WP_014569110 262 d----tlGEV----FHg-lATYRnl-paPTNIQSRfiiedlpygiDPLVRL--GKIL-SVPLPYSQKLATFa-Ha-Vfdq 326
NP_348099    264 -------TPLgklgISd-hCKSGw-----REMEYLd---------KRLLEW--AKKS-NLETPNINKLREHliKy-V--- 314
WP_058257816 265 e---rdaKEVff-wYAdmpTRAKg----PTKVDSRyise--dvpqGLVLLEslGLKY-KIATPICTALINIa-SaaLgrd 332
WP_011809288 260 a----gvSEM----NQq-mHRNGnggfgPKTALSRyvledvpfglVATARL--GRLV-DAPALLHEAGIALf-Ca-Aygr 325
WP_013251149 262 r------TKIgtlcVDd---HCRh---aPDEMRDLe---------VGFERI--RGLApDFPMPAWDALLARmgNw----- 313
WP_106447347 273 g----slAEM----EHe-lAQRPggvngPATLDTRyvtedvpfglVPTLEL--AALM-GVPMPLHEAGVRTm-Sa-Lygr 338
WP_005927504 257 -------TSLgklcASd-hAMNAi-----DEMSALn---------RDLKKF--FDEH-GAAYPVWQALETEagRy-L--- 307
5HWS_A       295 ----E-----R 296
WP_129886584 312 ----E-----A 313
WP_008780899 336 -lraEgrtpeK 345
WP_014569110 327 --vpEpdlrfi 335
NP_348099    315 ----Hkkvi-- 319
WP_058257816 333 -lrlEgrtleN 342
WP_011809288 326 dfsrEndllpA 336
WP_013251149 314 ---nEvcrrwg 321
WP_106447347 339 dfagEndllpA 349
WP_005927504 308 ----Q------ 308
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