Conserved Protein Domain Family
HprK

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COG1493: HprK (this model, PSSM-Id:224410 is obsolete and has been replaced by 441102)
Serine kinase of the HPr protein, regulates carbohydrate metabolism [Signal transduction mechanisms]
Statistics
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PSSM-Id: 224410
Aligned: 24 rows
Threshold Bit Score: 346.183
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
19704347   3 TYTTIREIVDK----LNLEILNE---GNLDLKIDIPNIYQIGYE---LVGFLDKEsdeLNKYINICSLKESRFIATFSKE 72  Fusobacterium nucle...
15887390     --------------------------------------------------------------------------------     Agrobacterium tumef...
17988317     --------------------------------------------------------------------------------     Brucella melitensis
16124494     --------------------------------------------------------------------------------     Caulobacter crescen...
20094948     --------------------------------------------------------------------------------     Methanopyrus kandle...
18202659   3 KKLFVSELIKH----FDLEVLNHdfpEIEDREILTPSIKRLGLE---LSGHFIYDa--ISGVIVGWGTNESKFFEKIGSE 73  Mycoplasma pulmonis
15793905   2 PSISVRRLFDDnqykLQLAWAAGn--SGADNRIGV-EADKPVLA---LVGHLNFI---HPNQIQVVGLAESEYLNRLESG 72  Neisseria meningiti...
15676635   2 PSISVRRLFDDnqykLQLAWAAGn--SGADNRIGV-EADKPVLA---LVGHLNFI---HPNQIQVVGLAESEYLNRLESG 72  Neisseria meningiti...
17545124   4 TGVTAQSIFDDnaadLKLSWVAGl--EGADRAFDV-DFAKEATSaadLVGHLNLI---HPNRIQVLGKPEITYYQRLSEE 77  Ralstonia solanacearum
15963795     --------------------------------------------------------------------------------     Sinorhizobium meliloti
19704347  73 RKEKVISEYMSLDFPALIFTKDAII--TEEFYYYAKRYNKNILLSNEKASVTVRKIKFFLSKALSIEEEYENySLMEIHG 150 Fusobacterium nucle...
15887390   1 --------------------------------------------------------------MNAERFNLHA-TAIVVDG 17  Agrobacterium tumef...
17988317   1 ------------------------------------------------------------MTPEEERSGLHA-TTLQLLG 19  Brucella melitensis
16124494   1 -------------------------------------------------------------------MIRHG-GLIALRH 12  Caulobacter crescen...
20094948   1 ----------------------------------------------------------------MERVVVHG-TLMDVFG 15  Methanopyrus kandle...
18202659  74 KAKSSIEEIFSRKIPMLVLSKGFDKnyYSTIIEIANKHKTPVIFYKASLSEINTILGIYLLQYFAKKVQVHG-TLVSVFG 152 Mycoplasma pulmonis
15793905  73 ETGYQFGDLFDISMSLVIVANGLPV--SPGLRDYCHKNDIPLLTSKLESPYLMDVLRIYLQRTLAASSVKHG-VFLDVFE 149 Neisseria meningiti...
15676635  73 ETGYQFGDLFDISMSLVIVANGLPV--SPGLRDYCHKNDIPLLTSKLESPYLMDVLRIYLQRTLAASSVKHG-VFLDVFE 149 Neisseria meningiti...
17545124  78 NRKRQMGELILLEPPFLVVADGVDP--PPDLELRCTRSSTPLFTSPISSAAVIDHLRLYLSRISAPRVTMHG-VFLDILG 154 Ralstonia solanacearum
15963795   1 --------------------------------------------------------------MNAPFVNVHG-TAIVLGT 17  Sinorhizobium meliloti
19704347 151 VG----VLMSGYSNARKG-VMIELIERG------HRMVTDKNLIIRRVGENDLVGYnAkkrEKLGHFYLEd--------- 210 Fusobacterium nucle...
15887390  18 TG----ILFTGPSGSGKSeLAFSFLTEAercglpAALIADDQIFVYRDGETIIAER-----PEAIAGLLE---------- 78  Agrobacterium tumef...
17988317  20 RG----VMIMGRSGAGKTeLALTLIERAasrreeAFLVADDRTLLHR-EGDRLIASv----PTALAGGVE---------- 80  Brucella melitensis
16124494  13 QGlwrgALIEGPSGAGKSdLALRALDQG------FRLVADDRVVTFA-AGGRLYGR-A---PETLAGLIE---------- 71  Caulobacter crescen...
20094948  16 VG----VLLVGPRGVGKSeTALELIRRG------HRLVSDDAVIVECDDSYEYPVGrP---PENLAGKMEirlalaelyc 82  Methanopyrus kandle...
18202659 153 MG----ILIVGDSGLGKSeAALELVQKG------HVLISDDAVLVSH-YGNKYFGK-A---PYITKNLIE---------- 207 Mycoplasma pulmonis
15793905 150 IG----VLITGHSGLGKSeLALELISRG------HSLIADDAVELFRIGPETLEGR-C---SPMLRDFLE---------- 205 Neisseria meningiti...
15676635 150 IG----VLITGHSGLGKSeLALELISRG------HSLIADDAVELFRIGPETLEGR-C---SPMLRDFLE---------- 205 Neisseria meningiti...
17545124 155 MG----VLIMGDSGLGKSeLGLELISRG------HGLVADDAVDFVRLGPDFIEGR-C---PPLLQNLLE---------- 210 Ralstonia solanacearum
15963795  18 TG----LLITGPSGSGKSaLALSCLSEVrhrgrfAALVADDRVDLTLENGRIVARC-----PAAIRGLIE---------- 78  Sinorhizobium meliloti
19704347 211 -----IKG-GYVDVTDHFGVKSTRIEKKINILIVLEEWNEKEf---YDRLGLDVQYEDFVGEKIQKY---IIPVRKGRNL 278 Fusobacterium nucle...
15887390  79 -----LRGsGIVSVKSVPSGVLHFAVTTVLSPENPRLPEDDEa-----LLMPCGGHLRLLRIPLSS----LVPYGKFAAL 144 Agrobacterium tumef...
17988317  81 -----IRGaGLFRIPYRV-------ATPLDLVVLLVNGDEAE------RYPGKERWI-FEEVSLPRL---LLPALSANGD 138 Brucella melitensis
16124494  72 -----VRGlGVVTAAAVSFAEIALVIRCVDTPGRVERLPEPR----FERIAGVDVP--VFDLWPPEP---AAPAKIRRMM 137 Caulobacter crescen...
20094948  83 pecgrVYTfSALKMKEGCDCGGDLKLRPIQDKIAVDVAELYGiralRSRKGIGVVIKMIPGPHHPHHdpsMRPDEPVSST 162 Methanopyrus kandle...
18202659 208 -----VRGlGLIDILSVHGLKSVLPECEINFVVELKDYEQNKs--nFDRLGNKVLKYQIGEWKIPKI---EIPIRQGRSV 277 Mycoplasma pulmonis
15793905 206 -----VRGlGILNIRHIFGETSIRPKKILQLIINLVEADDEYmk-qLDRLSIRTETESILNVNVRSV---TLPVAVGRNL 276 Neisseria meningiti...
15676635 206 -----VRGlGILNIRHIFGETSIRPKKILQLIINLVEADDEYmk-qLDRLSIRTETESILNVNVRSV---TLPVAVGRNL 276 Neisseria meningiti...
17545124 211 -----VRGlGLLDIKTIFGETAVRRKMKIKLIVQLVRRNDGe----FERLPLDSQYMDVLGLPIHMV---KIQVAAGRNL 278 Ralstonia solanacearum
15963795  79 -----IRGsGIAEVDTVSACVLDWAIMPVRAPFDPRLPPEEE------LQLEIGRNLPLLRLPVEGP---LSPVDALAAL 144 Sinorhizobium meliloti
19704347 279 AVIIETAALTFRLRRMGHNTPLEFLTKSQEIIErKKKER 317 Fusobacterium nucleatum subsp. nucleatum ATCC 25586
15887390 145 AQNLFKTNVK----------------------------- 154 Agrobacterium tumefaciens str. C58 (Cereon)
17988317 139 SNALSRAIEAFLFFERWPSAE------------------ 159 Brucella melitensis
16124494 138 QSLGVQS-------------------------------- 144 Caulobacter crescentus CB15
20094948 163 PSEEEKVVKWVKERDGRVFHLDVVPGRDTATLIeTVALQ 201 Methanopyrus kandleri AV19
18202659 278 ASLIEASANMFLSKLNGHDVLAMIQERSLNDE------- 309 Mycoplasma pulmonis
15793905 277 AVLVEAAVRNYILQLRGKDSTREFLERHQTQLK-ENEQH 314 Neisseria meningitidis Z2491
15676635 277 AVLVEAAVRNYILQLRGKDSTREFLERHQTQLK-ENEQH 314 Neisseria meningitidis MC58
17545124 279 AVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQaEAASH 317 Ralstonia solanacearum
15963795 145 LPQI----------------------------------- 148 Sinorhizobium meliloti
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