3ISY


Conserved Protein Domain Family
BsuPI

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pfam12690: BsuPI 
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Intracellular proteinase inhibitor
This is a bacterial domain which has been named BsuPI in Bacillus subtilis. This domain is found in Swiss:P39804, where it has been suggested to regulate the major intracellular proteinase (ISP-1) activity in vivo. The structure of proteins in this family adopt an Ig-like fold.
Statistics
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PSSM-Id: 432721
Aligned: 41 rows
Threshold Bit Score: 96.1414
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3ISY_A           7 VVLSIDAIQEPE-QIKFNXSLKNQSERAIEFQFSTGQKFELVVY-DSEHKERYRYSKEKXFTQAFQNLTLESGETYDFSD 84  Bacillus subt...
WP_014051943     2 LETTIDAQQCGD-IVAFAIRITNPDDEDVELSFSDSQRVRVVVYsTTEDEPRWRSDEDQLFMQMLGSQVIRAGDETIFEE 80  halophilic ar...
jgi:Halsa_2329  51 VILAEKEYSVQD-KLEIKIEIINNSDSERTLEFSSGHKYNIYVK-DESGTKIYSWAEDKMFIQAFQYVDISAGETHYFEQ 128
jgi:Cthe_1192  202 FETRGTYEIKDD-KVVFNFELVNHYKETKELMFGSGQQFELTIT-DEKGNEVYRYSDGKFFTLALIMKTINPGESIKWQD 279
Q9K8T7          49 VNVSVSAETVGD-QIEATITLINTTDQDVHFQFSSGQQYELILK-NEAGDTVYRYSDDKMFTMALIDETLAAGESKTWTE 126 Bacillus halo...
ADC48523        42 WAVNVTTEQNGEgEVVVDIEITNQMDEAATLDFTSGQKYELVVV-DEEGNEVYRYSNEMMFTMALTSETFEPGETKSYQE 120
WP_041815389    38 VVLTVDPVQKGS-SVQFNMSLKNESDRDIEFTFNTSQKFELSVY-DENGNEQYRYSKDRMFTQAIQSFVLKKGEAYDFQD 115 Bacillus pumilus
CCG44624        57 LNMEANVETSEE-TADFQMSLENTSDETVTLGFTSSQEYEIHVT-NAEGESVYTFSADKMFTQEMINKDLVAGESLTAEE 134
jgi:EAT1b_2772  43 LDTEMAYDASAK-TLSATISMTNPNEEAVDVTFNSSQRFQLVV--KKGDQTVFDYGSDYMFTESVIEEKWEANDKKVFDE 119
jgi:Bcell_2956  65 FLYSVDASLEDN-ALQVSITLKNEAESARKLEFSSGHQFDIIVK-DQEGNVIYDYAADRMFTQAFIFEEVGESEALTFND 142
3ISY_A          85 VWk-----E-VPEPGTYEVKVTFKGRAE 106 Bacillus subtilis
WP_014051943    81 TW------G-EPEPGEYRAVGEVVCSGR 101 halophilic archaeon DL31
jgi:Halsa_2329 129 EId----lS-QFEKGDYILEVELLSVNY 151
jgi:Cthe_1192  280 EWdmkdkdGnKLTSGKYKAKIEIMVVQE 307
Q9K8T7         127 SIp----aG-DLESGTYTLLAEVVVAAV 149 Bacillus halodurans
ADC48523       121 TLst-----dQWSSSTHTIYIEVVAAAV 143
WP_041815389   116 TWs-----N-GVKPGTYEAVVTFKGKAE 137 Bacillus pumilus
CCG44624       135 TWt-----G-IEEPGDYEATITFLVNSI 156
jgi:EAT1b_2772 120 VFp------lTLEPGEYSVEVIGLGQVD 141
jgi:Bcell_2956 143 QW------Y-SESLGDYEVLQVEATLLP 163
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