Conserved Protein Domain Family
SPO22

?
pfam08631: SPO22 
Meiosis protein SPO22/ZIP4 like
SPO22/ZIP4 in yeast is a meiosis specific protein involved in sporulation. It has been shown to regulate crossover distribution by promoting synaptonemal complex formation.
Statistics
?
PSSM-Id: 462542
Aligned: 74 rows
Threshold Bit Score: 85.4229
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
XP_004182645 199 LTIRNGNFETAKLYESQtdIPNNIDKLdPPLLLELCQIIYNSTVDLKelksvkctkpgHITQQFTDSdhlevikfiiYFL 278 
Q14AT2       176 SAVAQGDFKKASMCVLR--CKDMLMRL-PNMTKYLHVLCYNLGIEAS-----------KRNKYKESS----------FWL 231  house mouse
XP_008121014 167 SAMAQGDFQKTTTCIQR--CKDILMRL-PNEASYLSLLCYNFGVETY-----------QRKNYEQSS----------FWL 222 
XP_014344536 174 SAVSQGNFQKAMACVGR--CKDMLLRL-PKEMGYLSLLCYNFGVETY-----------EQKRYEESA----------FWL 229 
XP_015207083 172 SAVAQGSNQEAVSCMQR--CRDMLHRL-PKESGYLSLMCYNFGVDTY-----------KLKKFEESS----------FWL 227 
XP_023184569  67 SAVSQENSGEAKVYMQR--CKDMLQRI-PKDTAYLSLMCYNFGVDTY-----------NLRKYEDST----------FWL 122 
CAG09799      46 SALCQGNNAEALTCIQR--CKDMLLRL-PKDTAYLSLMCYNFGVDTY-----------NMRKFEDSA----------IWL 101 
XP_022540006 170 SAVAQENHQEAVSCMQR--CKEMLLRL-PKETGYLSLICYNFGVETY-----------NQKKLEESS----------FWL 225 
CAQ13439     169 SAVSQEQHQVAVSCIQR--CKEILLRL-PKETGYLSLICYNFGVDTY-----------SQGKHEEST----------FWL 224 
XP_031158809  67 SALSQGNNHEAVVYMQR--CKDMLLRL-PKDTAYLSLMCYNFGIDTY-----------NLRKFEDSA----------FWL 122  pikeperch
XP_004182645 279 KKALEYLSldvkGlkgnlEYSNIRYNILLFLTDSFINfyEQLDSNIEDCQFYLNMLQNEYPkntEPFQLAIKLCKKKVSQ 358 
Q14AT2       232 GQSYEIGK----Mdr-rsVEPQMLAKTLRLLATIYLN--CGGEAYYTKAFIAILIANKEHL---HPAGLFLKMRILMKGN 301  house mouse
XP_008121014 223 SQSYEIGK----MdvkysTGKEMQAKVLRLLATVYLE--WDCRQYHDKALRAAAMANEEDL---HPAGFLLKLKILLKGG 293 
XP_014344536 230 SQSYEIGK----MdkkysPGSAVQAKVLRLLANVYLE--WDCRQYQEKALNAVRLANEENL---HPAGLYLKIKILLKCG 300 
XP_015207083 228 SQSYDIGK----MdrkysPGPAVQAKVLRLLATVYFE--WDCQLYQEKALNAVTLANKENV---HPAGLYLQVRILLKSG 298 
XP_023184569 123 SQSYDIGK----TsakygPGPDVLAKALRLLATVYLE--WDCQRFQEKALDAVILANKECV---STSGLYLKIRILLRSE 193 
CAG09799     102 SQSYDIGK----InvkyaPGSEIQAKILRLLATVYLE--WDCQRFQEKALNAVNLANKECM---STSGLYLKIRILQTCG 172 
XP_022540006 226 SQSYDIGK----MnpkysPGPEMQAKVLRLLATVYLE--LDCQKYQEKALHAVSLANKEFF---HPSGLYLKIRILVKSK 296 
CAQ13439     225 SQSYDIGK----MnmkysPGSEMQAKVLRLLATVYLE--WDHQKYLEKALQAVSLANKEHM---QLSGLYLKIRILVKGC 295 
XP_031158809 123 SQSYEIGK----MnvkyaPGSEVQAKVLRLLATVYLE--WDCQRFQEKALNAVSLANKECV---SASGLYLKIRILLRCG 193  pikeperch
XP_004182645 359 NQEVNIKEILMGLItsvdIYIHLDTilgci-sdfaELSTSDAVIILDYLLNnkvDFDSNSdiAEKIILSRYYLTVQSKTL 437 
Q14AT2       302 SCNEELLEAAKEILy---LAMPLEFylsiiqflidNKRESVGFRFLRIISD---NFKSPEd-RKRILLFYIDTLLQKDQD 374  house mouse
XP_008121014 294 ASDEDVGTAVAELIh---HKLPLDIyldsakllleYKREAIGFDFLKSVAR---LFEDTPd-VGRVILLHIKLLLQRMKE 366 
XP_014344536 301 CPDEEINGAIGELEk---HEVSLDVclntaellveHDRESLAYEFLKTLCK---HFEASPd-LGKVVLMHIELLLQRGKE 373 
XP_015207083 299 APDEHLKVAVTELId---ADVPLEVclntakllmaEDREALGFDFLKRVCK---HHEASPe-VGSALVLHIELLLQRGKE 371 
XP_023184569 194 ASDNHIRAGLDEMLe---SQVPLEVcqsavkllmsEDREMLAFEYLKCVSQ---HFGSSPd-LGAALVLHVELLLQRNKE 266 
CAG09799     173 ASDDDIRAGLNEILe---AEAALEEclstvnllmsEDREVLAFEFLKRVCQ---HFEASPd-LGTALVLHAELLLQRGKE 245 
XP_022540006 297 ASDEVVKSGLTELLd---SDVVLDVclstakllmaEDRETLAFDFLKRMCQ---HFESSPe-LGSVLLLHIELLLQKGKE 369 
CAQ13439     296 SPDEAVKSGLSELLd---CEVPLEVclstvkllveENREALAFDFLKRVCQ---HFESSPe-LGSALLMHIELLLQRDKE 368 
XP_031158809 194 AADDHIRAGLNEMLe---SKVYLEVclstvkllmsEDREVLAFEYLKRVCQ---HFESSPd-LGTALVLHIELLLQRGKE 266  pikeperch
XP_004182645 438 TIqeIISSIIKFSELikRLIVHNFSKHIAASIITLLWNAGKKFEKEEMFNESVEFYKLCL 497 
Q14AT2       375 MI--AEEKIKDVLKG--YQTRSRLSRDLVNWLHNILWGKASRSVKVQKYADALHWYSYSL 430  house mouse
XP_008121014 367 PL--AKRMIEDILAG--QTIGKQLPSESLNHLHLVLWDRAAQNYEAKSYSEALQWYNYSL 422 
XP_014344536 374 LL--AKQKVEDVITG--HYTGNQLSPETVNRFHIILWDRAAKNFEMKNYLDALQWYNYSL 429 
XP_015207083 372 LL--GKQKIEDVITG--HYTGRQLSPPTLDHFQLLLWDRASKNFESRNYSEALQWYNYSL 427 
XP_023184569 267 LL--AKQKIEDIITG--HYSGKQLTPDALTSLHVILWDQASKHFEAGNYAEALQWYNYSF 322 
CAG09799     246 LL--AKQKIEDIITD--HYTGKQLSPQALTCLHVMLWDKACKYFEARNYPEALQWYNYSL 301 
XP_022540006 370 LL--GKQKIEDAITG--HYSGRQLSQHNLNSLHLLLWDKASKNFEAKNYSEALQWYNYSL 425 
CAQ13439     369 LL--AKQKIEDAITG--HYTGKQLASQTLSSLHLLLWDRASKNFEAKNFSEALQWYNYSL 424 
XP_031158809 267 LL--GKQKIEDIITG--HYTGKQLTPQALTRLHVMLWDKASKHFEAKNYAEALQWYNYSL 322  pikeperch
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap