Conserved Protein Domain Family
type_IV_pilB

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TIGR02538: type_IV_pilB 
type IV-A pilus assembly ATPase PilB
This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking]
Statistics
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PSSM-Id: 274186
Aligned: 12 rows
Threshold Bit Score: 890.905
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAG36955      28 KLGELLSKAGQITTTQLETAK-KLVKRG--QRMSLVLRQLEYIDEGTVFNFLSRQHNYPAVVIEKEPPTAKVVQLLSYEQ 104 Desulfotalea ps...
tigr:MCA2096  12 GLAKSLVKAQLLSEADAQAYFeDARRKN--TPFVSYLVANKILDGLQIAQVAHQEFGLPLLDLDAVVFDIPPTQWVGEKL 89  Methylococcus c...
CAH12630      12 GIGQLLVLEKLLDKTKAIELHkLAAAEK--ISLLQYIVKNKILSAEQIALTAAQNFGVPMLDINCIDVGAIPVNLVNEKL 89  Legionella pneu...
CAG67312      21 GFIRRLVEEGYVNAQNMQQALeKAKKFK--QDIVPYLIDNFSISPLTIAEIISLEFGEPLLDLGVFDPALFLKDKIDEKL 98  Acinetobacter s...
P45792         8 GLALSLAASSLLSESDSQRYLsQAKAQR--KPFVTFLIENEILDSKALADFCELEYGVPLLDLAAFDLAEIPQKYLNQKL 85  Aeromonas hydro...
AAM38083      14 GIARRLVQDGAVEEAVARSAMdQASAAK--VPLPQWFAEKKLVTASQLAAANAVEFGMPLLDVSAFDASQNAVKLVSEEL 91  Xanthomonas axo...
P37094         4 GLLRILVQNQVVTVEQAEHYYnESQAG---KEVLPMLFSDGVISPKSLAALIARVFSYSILDLRHYPRHRVLMGVLTEEQ 80  Neisseria gonor...
AAQ61490       9 GLGRALVQHNMLLQQDADAISkQATTSH--LSFVEQLIQSKKMTSRDIAMFSSRVFGYPLLDLASLDTEQLPKGLVDDEV 86  Chromobacterium...
AAB65805       6 ELIAYMVKNKVATPEQLKEVQiSVQKKR--GNFLQQLLSDGLLDASKLSKINREVYNLPIVALRELNIRRELTAQFKEAV 83  Dichelobacter n...
BAC95543       4 NLATILRQAKQLSLTQEQACReTIQASG--VTAPEALLQLGFFQPDELTEQLSAIFGLPRTDLNQYDYQELCNQLGLREL 81  Vibrio vulnific...
AAR34865       5 RLGELLVRNNIITKEQLAKALdEQRTSGgqQRLGSILVKNGLVTEPDLTTFLSKQYGVPSINLSEFEADMAVVKIIPADV 84  Geobacter sulfu...
CAE79389       5 KIGEILVKQGLLKPDQLALAMeEQKKTG--QKLTNSIIQLGYLKDNQILRAVEKHFAVPGVEVNTFEIDATVIAMIPKDV 82  Bdellovibrio ba...
CAG36955     105 AKEYMALPLRVAGNTLQVTMVEPCDTAAVEALQDLVNKE-LAVCISPEKDIINAYKKYYGISDEEaKELYGDagdieeet 183 Desulfotalea ps...
tigr:MCA2096  90 IRRHHILPLLRRGNHLFVAVSDPTNFLGLDEITFQTRLV-TDCVLVEENKLSRCIEAVLDAADTS-LKQLLE-------- 159 Methylococcus c...
CAH12630      90 IKRHAMVPLFSRGTNLYLATDDPSKQASLKEIQFHTGLN-THAIVVEADKLSALIENLLTAKESQgLSEYVE-------- 160 Legionella pneu...
CAG67312      99 IQKYRIMPLVHRGHVLYVATSNPTNIEAMDAIRFNSKLK-VEPIIVEHDKLERLLSEHFVEETHFnFDTEEL-------- 169 Acinetobacter s...
P45792        86 IEKHHVLPIYTQGHTLYIAMSDPTNVSALEDFGFSFGLH-TEALLVEENKLTTAIGK-LLESDQDaLGMEDI-------- 155 Aeromonas hydro...
AAM38083      92 LQKHQVLPLFKRGNRLFVGVSNPTQTRALDDIKFHTNLV-VEPILVDEDQIRRTLEQWQASNAALgSALGDD-------- 162 Xanthomonas axo...
P37094        81 MVEFHCVPVFRRGDKVFFAVSDPTQMPQIQKTVSAAGIA-VELVIVEDDQLAGLLDWVGSRSTSLlQELGEg-------- 151 Neisseria gonor...
AAQ61490      87 IASRRLLPLLKRGNKLYIGTSDPTQTSAYHAITFKTGLT-VEVVVVEEDKLSKLIGRYQDNSTSAlKELESE-------- 157 Chromobacterium...
AAB65805      84 VRKHTAMPVYANGGRLFIATIDPNNRSMLEEFKYQGKFTsVEPIIANLDAIEALIEEHYAGLGGMdDLFDDE-------- 155 Dichelobacter n...
BAC95543      82 ITRHQALPLQKSNAGLILAVADPTNIQAEDDFRFATGVQ-VEIVLADCQELQAAIRRLYGKSIKQsQGSGLK-------- 152 Vibrio vulnific...
AAR34865      85 AQKYQIVPVNRAGSTLIIAMADPSNIFAIDDIKFMTGYN-VEVVVASESSIKTAIDKYYDQSASLaDVMN---------- 153 Geobacter sulfu...
CAE79389      83 CEKNTLIPLQKAGNTLVVAFADPSNIIVKEDLRFITRCR-IQAVVGTESAIMSGIEKYYGGSISt-KSLN---------- 150 Bdellovibrio ba...
CAG36955     184 DigITEVEDFGSIVAEAADdfEIEQDDVDEsmdqfnasDAPIIKLVNGILVKAVQDGVSDIHVEPYEKSMQVRYRKDGTL 263 Desulfotalea ps...
tigr:MCA2096 160 E--DLDSLQITAGDDEGPH--AEPEISGID--------DAPIVRFVNRLLLDAVRKGASDIHIEPYEKFLRIRFRHDGIL 227 Methylococcus c...
CAH12630     161 DsgDLEGLEISA-DDEDQD--IDTATSVTD--------DAPIVKFVNKILLDAIRQGASDIHFEPYEREYRIRYRQDGIL 229 Legionella pneu...
CAG67312     170 D----LDVEVDPHTTDD----DDEDDKLKD--------EAPIVKYINKLLIDAIRMSASDLHFEPYEKSYRVRYRVDGVL 233 Acinetobacter s...
P45792       156 DesEISELEVSDENSRL----DESVNTTDD--------DAPIVKYINKIMMDAIKRGASDLHFEPYETKYRIRFRIDGIL 223 Aeromonas hydro...
AAM38083     163 Ee-gMGDLDVSAGDEDMGAggDSGVDAKGD--------DTPVVKFVNKVLVDAIRRGASDIHFEPYEDDYRVRLRIDGLL 233 Xanthomonas axo...
P37094       152 ---QEEEESHTLYIDN----------EEAE--------DGPVPRFIHKTLSDALRSGASDIHFEFYEHNARIRFRVDGQL 210 Neisseria gonor...
AAQ61490     158 DfgDLEFADPDAQLDSGPQ-------TEVD--------DAPVVKFIHKMLLDAIGIGASDIHFEPYEKYYRIRYRVDGVL 222 Chromobacterium...
AAB65805     156 T----EEKDLDAISNALGG-----LDANEE--------EAPVVRFVTGMLLDAIRTGASDLHFEPYETTYRVRFRRDGVL 218 Dichelobacter n...
BAC95543     153 EihQDELANLVEVSDDEVEs---IEDLSQD--------ESPVSRFINQILLDAVRKGASDIHFEPYENQYRVRLRCDGIL 221 Vibrio vulnific...
AAR34865     154 DleMDDLE----VIGEDEDvdVSSLERATE--------DAPVVKLVNLILTDAIKKKASDIHIEPYERTFRVRYRIDGVL 221 Geobacter sulfu...
CAE79389     151 TmgVGDEDDF--ILSAGPAteVIDQDGGSE--------DAPIIKFVNSILADAIRKKVSDIHFEPYEKKYRVRFRIDGNL 220 Bdellovibrio ba...
CAG36955     264 YKSMNLPLTIKNALVARMKILAGLDITERRIPQDGRIKMRLGRN-RSVDFRVSSLPTLFGEAVVLRILDKSSLNVDLTKL 342 Desulfotalea ps...
tigr:MCA2096 228 HEVANPPPALGVKICARIKVMSRMDIAEHRIPQDGRIKMTLSRS-RAIDFRVNTCPTLFGEKIVLRILDPSSAQIGVEML 306 Methylococcus c...
CAH12630     230 HEVATPPASLSSRITARIKVMSNLDISERRIPQDGGFKMKISKS-RAIDFRVSTCPTSAGEKVVMRVLDSGAAKLGIEAL 308 Legionella pneu...
CAG67312     234 RLIATPPLQLATRLASRLKVMSQMDISEKRVPQDGRIKLKMSKS-KTIDFRVNSLPTLFGEKIVLRILDPASAMLGIDAL 312 Acinetobacter s...
P45792       224 HEIATPPVNLANRFSARLKVMARLDIAERRLPQDGRIKLKLSRN-KSMDMRVNTLPTMWGEKIVIRLLDSSAARLNIEQL 302 Aeromonas hydro...
AAM38083     234 KNVAKAPVKLNQRIAARLKVMSQLDIAEKRVPQDGRIKLNLSKT-KQIDFRVSTLPTLFGEKVVLRILDGSAAKLGIDKL 312 Xanthomonas axo...
P37094       211 REVVQPPIAVRGQLASRIKVMSRLDISEKRIPQDGRMQLTFQKGgKPVDFRVSTLPTLFGEKVVMRILNSDAASLNIDQL 290 Neisseria gonor...
AAQ61490     223 KEVAQPPLLLKEKIASRIKVISRLDISEKRLPQDGRLKLVISKT-RAIDFRVSTLPTLYGEKIVMRILDSSGASLDIDQL 301 Chromobacterium...
AAB65805     219 QEVAAPPPSIATRITARLKVMADLDIAEKRVPQDGRIKLYVSDT-KAIDFRVNSLPTLWGEKIVLRILDSSAAKLNIEIL 297 Dichelobacter n...
BAC95543     222 VEVQQPPSHLSRRLSARIKILSKLDIAERRLPQDGRIKLRLNQE-TAIDMRVSTLPTLFGEKIVLRLLDSSSSSLDIDKL 300 Vibrio vulnific...
AAR34865     222 YEVMKPPLKLKNAITSRIKIMADLDIAERRLPQDGRIKIKMGGG-QDMDYRVSVLPTLFGEKVVLRLLDKSNLQLDMTKL 300 Geobacter sulfu...
CAE79389     221 VEATAPPAGTAAAIASRIKIMSKLDIAEKRRPQDGRLKVRT-KA-KEMDFRVSVLPTLWGEKVVLRLLDKSNLQLDMTKL 298 Bdellovibrio ba...
CAG36955     343 GFQEDTFAGLKRCLKRPQGLVLVTGPTGSGKTVTLYSALNSLNSEDIKILTAEDPVEFNFRGINQVNVHPEVGMTFAAAL 422 Desulfotalea ps...
tigr:MCA2096 307 GFEPEQRDNFLRALEKPYGMILVTGPTGSGKTVTLYTGLNLLNRVEANISTVEDPVEITVPGINQVNVNYKTGLTFAEAL 386 Methylococcus c...
CAH12630     309 GFNPVQRTNFLKAIQRPQGMILVTGPTGSGKTVTLYTALNILNTIEVNISTAEDPVEIKVPGINQVNINPKAGLTFSGAL 388 Legionella pneu...
CAG67312     313 GYEPEQKALFMEALNKPQGMLLITGPTGSGKTVSLYTGLNILNTEHANISTAEDPVEINLEGVNQVNVNPKVGLTFAAAL 392 Acinetobacter s...
P45792       303 GFDDRQKAQYLRALSKPQGMILVTGPTGSGKTVSLYTGLNILNTTEVNISTAEDPVEINLPGVNQVQVNPKAGLTFASAL 382 Aeromonas hydro...
AAM38083     313 GYEPDQQKLFLEAIHKPYGMVLVTGPTGSGKTVSLYTALGILNDETRNISTAEDPVEIRLPGVNQVQQNNKRGMTFAAAL 392 Xanthomonas axo...
P37094       291 GFEPFQKKLLLEAIHRPYGMVLVTGPTGSGKTVSLYTCLNILNTESVNIATAEDPAEINLPGINQVNVNDKQGLTFAAAL 370 Neisseria gonor...
AAQ61490     302 GFEPEQKAHLLKAIARPYGMVLVTGPTGSGKTVSLYTCLNILNKPDTNISTAEDPVEINLPGINQVNVNEKAGLTFASAL 381 Chromobacterium...
AAB65805     298 GFEPDQKQQYLDAISKPQGLVLVTGPTGSGKTVSLYTGLNILNKPTVNISTAEDPVEINLPGINQVNVNPKTGLDFSAAL 377 Dichelobacter n...
BAC95543     301 GYNPQQKQLYLDALRKPQGMILMTGPTGSGKTVSLYTGLSLLNRPEVNISTAEDPVEINLPGINQVQVKPKIGFGFAEAL 380 Vibrio vulnific...
AAR34865     301 GYEPTALSYFKEAIHKPFGMVLVTGPTGSGKTVSLYSALSELNKTTENISTAEDPVEFNFAGINQVQMHEDIGLTFAAAL 380 Geobacter sulfu...
CAE79389     299 GFEEDDLKLFKATINLPQGMVLITGPTGSGKTTTIYSALAELNQPDVNISTAEDPVEFNLEGINQVQMNPDIDLNFSSAL 378 Bdellovibrio ba...
CAG36955     423 KAFLRQDPDIIMVGEIRDMETAEIAIKAAMTGHLVFSTLHTNDSAATIARLVDIGIPPYMLASSVSMVLAQRLGRRLCSK 502 Desulfotalea ps...
tigr:MCA2096 387 RAFLRQDPDIIMVGEIRDLETAEIAVKAAQTGHLVLSTLHTNDAPQTLNRLMQMGIPAFNIASSVLLIMAQRLARRLCPR 466 Methylococcus c...
CAH12630     389 RSFLRQDPDIIMVGEIRDLETAEIAIKAAQTGHLVLSTLHTNSAAETLNRLVNMGIPTFNIASSVTLIIAQRLARKLCNQ 468 Legionella pneu...
CAG67312     393 RSFLRQDPDIIMVGEIRDLETAEIAIKAAQTGHLVMSTLHTNNAAETLTRLRNMGVASFNIATSVNLVIAQRLARRLCSQ 472 Acinetobacter s...
P45792       383 RSFLRQDPDVVMVGEIRDLETAEIAIKAAQTGHLVLSTLHTNSAAETLTRMMNMGVPAFNIASSVTLIMAQRLARKLCDH 462 Aeromonas hydro...
AAM38083     393 RSFLRQDPDIIMVGEIRDLETAEIAIKAAQTGHMVLSTLHTNDAPQTIARLMNMGIAPYNITSSVTLVIAQRLARRLCNN 472 Xanthomonas axo...
P37094       371 KSFLRQDPDIIMVGEIRDLETADIAIKAAQTGHMVFSTLHTNNAPATLSRMLNMGVAPFNIASSVSLIMAQRLLRRLCSS 450 Neisseria gonor...
AAQ61490     382 KAFLRQDPDVIMVGEIRDFETADIAIKAAQTGHMVFSTLHTNDAPSTLTRMLNMGVAPFNIASSVLLIMAQRLARRLCSH 461 Chromobacterium...
AAB65805     378 KAFLRQDPDIIMVGEIRDITTAEIAVKAAQTGHLVLSTLHTNDVPQTIARLVNIGIEPYNIAASVNLIMAQRLARRLCNN 457 Dichelobacter n...
BAC95543     381 RSFLRQDPDIVMVGEIRDLETAEIAVKAAQTGHLVLSTLHTNSAAETIVRLSNMGIASFNLASSLSLIIAQRLARRLCSH 460 Vibrio vulnific...
AAR34865     381 RSFLRQDPDIIMIGEIRDFETAEIAIKAALTGHLVLSTLHTNDAPATINRLLNMGVEPFLVASAVNLITAQRLARRVCSE 460 Geobacter sulfu...
CAE79389     379 KSFLRQDPDVVMVGEIRDLETAEIAFKAASTGHLVVSTLHTNDAPGTVIRLTEMGVAPYIITSTVNLIVAQRLVGKVCES 458 Bdellovibrio ba...
CAG36955     503 CKEV-VEYSPEELIKLGFHQEELDD--LVIYGPVGCSECSgFGYKGRVGFFELMEVNEEVAKAISAQVPEDQLRKIACQE 579 Desulfotalea ps...
tigr:MCA2096 467 CKRE-EKVPPEVLLASGFREEDIGN--FTLFGPAGCDQCV-KGYKGRVGIYQVMPISEEINRIILEGGNVMALTEQAHAE 542 Methylococcus c...
CAH12630     469 CKAVrDDFTNQGLIELGFKEADLVN--LKLYKAVGCEQCT-SGYRGRVGLFEVLPMTKELGQLIMSGGNSLDILKLAQSE 545 Legionella pneu...
CAG67312     473 CKRP-IQVPERSLLEMGFTPEDLAQpeFQIFEPVGCHDCR-EGYKGRVGIYEVMKITPEISKIIMEDGNALEIAATAETL 550 Acinetobacter s...
P45792       463 CKAP-EVVPEAELLELGFTQQQLAAg-LRLFKPVGCKDCS-GGYKGRVGIYEIMLMSENIAKLIMQGANSLQIAAIAQKE 539 Aeromonas hydro...
AAM38083     473 CKRK-STLPDNALLAEGFTPAQLAAg-IELYEAVGCDECT-EGYKGRTGIYQVMPMTDEIGAIVLEGGNAMQIAEAAQAI 549 Xanthomonas axo...
P37094       451 CKQEvERPSASALKEVGFTDEDLAKd-WKLYGAVGCDRCRgQGYKGRAGVYEVMPISEEMQRVIMNNGTEVGILDVAYKE 529 Neisseria gonor...
AAQ61490     462 CKQPvEIP-KEALLRAGFTKEDLAGg-WHPYGPVGCEECRnTGYKGRVGIFEAMPISDAMMRLIMKNGTSVDISDLAKEE 539 Chromobacterium...
AAB65805     458 CKIRdRKHHTEELLALGFHEEDLDD--LKIYAPKGCERCSyQGYRGRAGIYQVVPISEAIAELILKNASAAEIAEQCLKE 535 Dichelobacter n...
BAC95543     461 CKQP--HPYNATFELLGLKADDLIY----QADRQGCHHCT-HGYSGRVGIYEVMPFDEQLAEAIVKGASVQSLEMLARQK 533 Vibrio vulnific...
AAR34865     461 CKAV-EEIPIQALIDAGVPPEEAPE--YVCFRGTGCAKCNnTGYKGRVGFYQVMPMLEEIRELILNGANTAEIKRESMRL 537 Geobacter sulfu...
CAE79389     459 CKAP-VEVPAQTLLNLGVPQAEIGD--YKLMRGKGCANCNnTGIKGRLAIYELLAMTEKMKEAILKGASTGQLRFLAREQ 535 Bdellovibrio ba...
CAG36955     580 GMSPLREAALQKVREGVTSIEEALKRTVA 608 Desulfotalea psychrophila LSv54
tigr:MCA2096 543 GIADLRESGLKKVKAGITSLEEIDRVTRD 571 Methylococcus capsulatus str. Bath
CAH12630     546 GMLTIFQSGIEKVKEGITTIEEVNRVTVD 574 Legionella pneumophila str. Paris
CAG67312     551 GFNNLRRSGLKKVMQGVTSLQEINRVTSE 579 Acinetobacter sp. ADP1
P45792       540 GMRTLRISGLEKARIGVTSLAEINRVTTN 568 Aeromonas hydrophila
AAM38083     550 GIRDLRQSALMKAANGVTSLAEINRVTKD 578 Xanthomonas axonopodis pv. citri str. 306
P37094       530 GMVDLRRAGILKIMQGITSLEEVTANTND 558 Neisseria gonorrhoeae
AAQ61490     540 GMVDLRRAGLLKVMSGVTSLAEVEAVTND 568 Chromobacterium violaceum ATCC 12472
AAB65805     536 GYLDLRQAALNKVKQGLTSIEEVLRVTSE 564 Dichelobacter nodosus
BAC95543     534 GMMTLKDSGLEKLKQGITSLEELQRVLYL 562 Vibrio vulnificus YJ016
AAR34865     538 GIKTMRQSGLTKLKEGVTSFEEVLRVTVA 566 Geobacter sulfurreducens PCA
CAE79389     536 GMRTLRRSALLKLKRGVTTIEEVLNASVK 564 Bdellovibrio bacteriovorus HD100
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