3TX3


Conserved Protein Domain Family
EI24
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pfam07264: EI24 (this model, PSSM-Id:399918 is obsolete and has been replaced by 462129)
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Etoposide-induced protein 2.4 (EI24)
This family contains a number of eukaryotic etoposide-induced 2.4 (EI24) proteins approximately 350 residues long as well as bacterial CysZ proteins (formerly known as DUF540). In cells treated with the cytotoxic drug etoposide, EI24 is induced by p53. It has been suggested to play an important role in negative cell growth control.
Links
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Statistics
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PSSM-Id: 399918
Aligned: 290 rows
Threshold Bit Score: 32.1505
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3TX3_B               16 YIGRGLELIRTKGLRRYVVVPILTNLIlfslaftwlygevdywlnrf--------mswlpdffqwlefilwplavITIIA 87  Idiomari...
BoseInst:TKWG_22860  12 aFSKAIATQMRPSMLLAVILPFVIALItavillvfawgpldnwldntamhwgwfqsvstrlsgwgfvtmsdwltgVLTFV 91  Advenell...
Q7VTW0               26 AFKRALVSQCHPNMLFAVLLPFLIALLgailllwlfwtplnewlrfeasqwqainqvddwmvaaglfslkiylvpVIAAA 105 Bordetel...
zhongguo:PT7_1987    23 AFKRALVSQCHPKMLLALFLPFLIALLgaiillwafwdpltswlnmqasewgfinqldqwmlaiglfsiklylvpLLAVG 102 Pusillim...
WP_052355886         23 AFRRAAASQLHPRMIAALFLPFVIAFLgavvllwffwqpltgwldqeasswglfntidgwlvavglfslklwlvpLLAAG 102 Castella...
goetting:MIM_c10330  24 AFGRALVSQLQPRMLLALLLPFAAALIamlffarflwgpvadwlnlfvtqsemmtdmeswmagvglfsltvyvvhILVFV 103 Advenell...
WP_022771829          7 sFWRALLCSMQPRVLFLSLVPLALMLLlavgfftlywdfaldlasealtasawvqsvsewlqqhglvslvsvvapLLVMF 86  Candidat...
WP_011810880          7 SFWRAGAYCLRPRVIALSLLPLLLIAVlalgggyfywdaavqgmrslldas-vmgliwnwwqgtglgdprsvmaqMMVIL 85  Verminep...
WP_011804619         11 SFWRAVGYCLMPRVIALSLLPLVLITVvalgggylfwttavawtqtalesstwlgllwgwlhnfgvdnlpvalapLLVLM 90  Comamona...
jgi:Aave_1440         7 SFWRAVGYCLHPRVIALSLLPLLLIVLltglfwylwwdgavaslgallags-ewlsflwgwlqgfgvegpallapVLLVV 85  Acidovor...

3TX3_B               88 LFSFIFSTIMHLIAAPF-NGLLAEKVER-Y----------------EsgeslgdegflglfkdiprtlkREMQKLMYYIP 149 Idiomari...
BoseInst:TKWG_22860  92 ALLAVSGIAGLAAAAILvMPMALKVIGDgSypdvqkkgenatvtslA----------------------NTVKVSTIFVV 149 Advenell...
Q7VTW0              106 ILLPISGILGLAIAAVFvMPLVLRHVGGrEyaglarqgrnatavsvW----------------------NALWVSLAFGA 163 Bordetel...
zhongguo:PT7_1987   103 ILLPISGILGLIIAAVFvMPIVLRHLEKgEyqgvlrqgrystavgaW----------------------NAIWVGCIFAI 160 Pusillim...
WP_052355886        103 LLLPMAGILGLVIAAVFvMPIVLRHLEHrEyrglnrqgrnttalgvW----------------------NAIWVGLLFCL 160 Castella...
goetting:MIM_c10330 104 IMVTLGSSIGLLIAAVLvMPMVVGHVARtDypeldrrgrqvfvssmV----------------------NSIKVVLVFIA 161 Advenell...
WP_022771829         87 AASIVVLVLALLLVALLmTSSLTDFVAArRfphlerkkggsllqsvC----------------------WSIGSTALALL 144 Candidat...
WP_011810880         86 AAAPLLVLVSLLIVALLmTPALVALVAQrRfpqlerkrggsfiasvA----------------------WSLGSTVLALL 143 Verminep...
WP_011804619         91 GATPLIVIVCVLAVAVLmAPAIVTLVAQrRfaqlqrkrggsflasvL----------------------WSLGSTIAALI 148 Comamona...
jgi:Aave_1440        86 LITPAIVVLSVLAVAMLmAPALVSLVARrRfpslerrgrgsflaslA----------------------WSLGSTVAALV 143 Acidovor...

3TX3_B              150 RALGFFLL-SLviPvIgQ----VLWYIFVCWmMSIQYLDYPFdnhklSFPRMRSELHQQRSKTLGFGFGVTVLTMIPLIN 224 Idiomari...
BoseInst:TKWG_22860 150 GWLITLPLwLI--PfAgIalslFWGAYAFSHmTRLDAIVEHA-----TLEERAYVLRHYSRGFWLIGLICAAIALIPFAG 222 Advenell...
Q7VTW0              164 GWLLTLPFwLI--PpMvVilsvFWWAFAFTRmLRLDAIVEHA-----SPAERAILLKRHNSGFWLIGLVCSLLNLLPPAW 236 Bordetel...
zhongguo:PT7_1987   161 GWLVTMPLwLI--PpFaVllplFWWSFAFTRmLRVDATIEHA-----SAQERRLLWRQHNRQWWLIGCILALINLFPPAW 233 Pusillim...
WP_052355886        161 GWLVTMPLwLI--PpMaLvlpvFWWAFALNRmLRVDAMIEHA-----SAAERRLLWRRHNRQLWLIAACLAVVNLIPLFW 233 Castella...
goetting:MIM_c10330 162 GWVITLPLwLI--PpVaVllhvFWWAYAFTHmLRFDALVEHA-----TEQERAQVIARRRGGGWLIGTICAILNLIPLTW 234 Advenell...
WP_022771829        145 ALLLSVPLwLV--PpLvLlvppLIWGWLTYRvMAFDALGIHA-----SREERTELFRRHRLELLSIGLIVGYLGAVPGVL 217 Candidat...
WP_011810880        144 ALLVSIPLwLV--PpLvLivppLIWGWLTYRvMAFDALAGHA-----SKQERQEILRRHRTSLLGIGILTGYLGAAPSIL 216 Verminep...
WP_011804619        149 ALVLSMPLwLV--PpLvLilppLIWGWLTYRvMAFDALAEHA-----SKPERQEIFKRHQLSLLSIGVLSGFLGAAPGIV 221 Comamona...
jgi:Aave_1440       144 ALVLSIPLwFI--PpLvLvlppLIWGWLTYRvMAFDALGEHA-----DKAERETIMRQYKMQLLGIGVVTGYLGAAPGIV 216 Acidovor...

3TX3_B              225 LII 227 Idiomarina loihiensis
BoseInst:TKWG_22860 223 FVM 225 Advenella kashmirensis WT001
Q7VTW0              237 IIL 239 Bordetella pertussis
zhongguo:PT7_1987   234 LFL 236 Pusillimonas sp. T7-7
WP_052355886        234 LVM 236 Castellaniella defragrans
goetting:MIM_c10330 235 IVL 237 Advenella mimigardefordensis DPN7
WP_022771829        218 WAs 220 Candidatus Symbiobacter mobilis
WP_011810880        217 WAs 219 Verminephrobacter eiseniae
WP_011804619        222 WAs 224 Comamonadaceae
jgi:Aave_1440       217 WAs 219 Acidovorax citrulli AAC00-1
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