Conserved Protein Domain Family
gyrB

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PRK05644: gyrB 
DNA gyrase subunit B; Validated
Statistics
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PSSM-Id: 235542
Aligned: 446 rows
Threshold Bit Score: 1029.65
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
25026562    4 TEHNYDASSITILEGLEAVRKRPGMYIGSTGSRGLHHLIWEVVDNSVDEAMAGYADRVDVTLLEDGGVEVIDNGRGIPVE 83 
86606189    1 MTENYGAEQIQVLEGLEAVRRRPGMYIGSTGPKGLHHLVYEVVDNSVDEALAGYCNEIEVTLHPDGSVSVLDNGRGIPVD 80 
86607821    1 MTENYGAEQIQVLEGLEAVRKRPGMYIGSTGPKGLHHLVYEVVDNSVDEALAGYCNDIQISLHPDGSVSVLDNGRGIPVD 80 
81301300    1 MANEYGASQIQVLEGLEPVRKRPGMYIGSTGPKGLHHLVYEVVDNAVDEALAGYCNTIDVRLLEDGSCQVTDNGRGIPTD 80 
56751624    1 MANEYGASQIQVLEGLEPVRKRPGMYIGSTGPKGLHHLVYEVVDNAVDEALAGYCNTIDVRLLEDGSCQVTDNGRGIPTD 80 
124485239   1 MTDNYDASHITVLEGLTPVRERPAMYIGSTDTRGLHHLVYEVVDNSIDEALAGFCKHIVIIINPNGSVSVEDDGRGIPVD 80 
37522075    1 MTETYGAEQIQVLEGLEHVRKRPGMYIGSTGPRGLHHLVYEIVDNSVDEALAGHCKHIAISLGADGSATITDDGRGIPTD 80 
126179353   1 MTDTYDASHITVLEGLRPVRERPAMYIGSTESRGLHHLVYEVVDNAVDEALAGFCDLIQVTVNRDGSVSVDDNGRGIPVD 80 
154151176   1 MTDTYDASHITVLEGLQPVRERPAMYIGSTDTRGLHHLVYEVVDNSIDEALAGFCNRICVVINKDGSLMVEDNGRGIPVD 80 
219851686   1 MTESYDASHITVLEGLQPVRERPAMYIGSTDTRGLHHLVYEVVDNAVDEALAGFCDLISITINRDGSCTVDDNGRGIPVD 80 
25026562   84 MHAS-GAPTVQVVMTQLHAGGKFDSDSYAVSGGLHGVGISVVNALSTRVEAHIKKDGKHWYQNFNNSIP-EDLVEGA--- 158
86606189   81 IHPKtGQSALVTVMTVLHAGGKFGGGGYKVSGGLHGVGVSVVNALSEWLEARVWREGKVYFQRFERGAVvGSLQSepq-- 158
86607821   81 IHPKtGQSALVTVLTVLHAGGKFGGGGYKVSGGLHGVGVSVVNALSEWVEVTVWREGKVYFQRFERGAVvGSLKSepq-- 158
81301300   81 IHPQtGKSALETVLTILHAGGKFGGGGYKVSGGLHGVGVSVVNALSEYVEVTVWREGKTHQQRFEQGNPiGELQVAP--- 157
56751624   81 IHPQtGKSALETVLTILHAGGKFGGGGYKVSGGLHGVGVSVVNALSEYVEVTVWREGKTHQQRFEQGNPiGELQVap--- 157
124485239  81 IMPKqNKSALEVVMTVLHAGGKFDKNTYQVSGGLHGVGVSVVNALSTRLTAEVYRDGNIYSMVFGKGVLlQPLTSRP--- 157
37522075   81 THPRtGKSTIETVLTVLGAGGKFGGGGYKVSGGLHGVGAAVVNALSTILTATIWREGKQYIQRFHRGIPeGGLAVS---- 156
126179353  81 LMPQyGKSALEIVLTVLHAGGKFDKNTYQVSGGLHGVGVSVVNALSSWLDATVFKDGNVYAMQFRQGLVaKPLASRPete 160
154151176  81 TMEKnHKSALEVVLTVLHAGGKFDKETYQVSGGLHGVGVSVVNALSNWLSARVYRDGNIYEMRFSQGKTtLPLTTRE--- 157
219851686  81 KMQKnGKSALETVLTILHAGGKFDKNTYQVSGGLHGVGVSVVNALSVSLVADVFRDGNRYRMEFAQGKVvSPLSVHK--- 157
25026562  159 ---NA--------------------------------------------------------------------------R 161
86606189  159 -paGA--------------------------------------------------------------------------Q 163
86607821  159 -pkGS--------------------------------------------------------------------------N 163
81301300  158 ---DAd-------------------------------------------------------------------------D 161
56751624  158 --dAD--------------------------------------------------------------------------D 161
124485239 158 ---ETdeeyllrqkr-------------------------------------------------------ldkegqpkeT 179
37522075  157 ---SDs------------------------------------------------------------------------qK 161
126179353 161 hemEAryeerygar---------------------------------------------------------dgqpldyeR 183
154151176 158 ---ETlaellaryqqwygepapfaraspalavssgaipgqvpvtppgtvtgqldlttaahyptgneqedrasllatlgnK 234
219851686 158 ---ETlselleryrrryrsep------------------------------------------prevetkealfadegaK 192
25026562  162 GTGTSIRFWPDAEIF-ETTDFDFDTISRRLQEMAFLNKGLTMTLTDNRasdeelelealaeqgdtavelsldqidadget 240
86606189  164 RRGTEVRFKPDELIFpE-REFDYSLLAARLRELAYLNAGLKIIFSDLR-------------------------------- 210
86607821  164 RRGTEVRFKPDGLIFpE-REFDYAVLAARFRELAYLNAGLKITFSDLR-------------------------------- 210
81301300  162 RRGTQVRFKPDATIFsETTEFDYGTLASRLKELAYLNAGVRIDFTDERlql----------------------------- 212
56751624  162 RRGTQVRFKPDATIFsETTEFDYGTLASRLKELAYLNAGVRIDFTDERlql----------------------------- 212
124485239 180 TTGTRITFYPDGSIF-ETTEFDYDVLAHRFRELAYLNKGLEIHVEDHR-------------------------------- 226
37522075  162 RRGTMISFLPDPEIFtTGVDFDFDTLLSRFRELAFLNAGVEFRFSDLR-------------------------------- 209
126179353 184 LRGTRITFQPDRSIF-ETVEFDYDVLDHRLRELAYLNSGLTIVLRDER-------------------------------- 230
154151176 235 LTGTRIHFVPDASIF-ETTTFDYDVLAHRLRELAFLNAGLTIIITDERt------------------------------- 282
219851686 193 LSGTIITFQPDDSIF-ETVTFDYDVLVHRLREMAFLNRGITIRITDLR-------------------------------- 239
25026562  241 qlvdaevtdapkkPKKRekkKIFHYPNGLEDYVNHLNRTKTPIHpSIVSFE--AKAA--EHEVEIAMQWN-SSYKESVHT 315
86606189  211 --------------RDPphrEVYQFAGGIKEYVAFINHEKTPIHpDIIYVR--GERD--GVEVEAALQWCaDVYTDTLIG 272
86607821  211 --------------RDPphcETYQYAGGIKEYVAFINHEKTPIHsDIIYIQ--GERD--GVEVEVALQWCsDVYTDTLIG 272
81301300  213 -----------tkNHEPh-qETYYFEGGIREYVAYMNTDKQALHsEIIFVQ--SEKD--GVQVEAALQWCvDAYSDNILG 276
56751624  213 -----------tkNHEPh-qETYYFEGGIREYVAYMNTDKQALHsEIIFVQ--SEKD--GVQVEAALQWCvDAYSDNILG 276
124485239 227 -------------TGDS---DTFCYEGGLRQFVAHLNEGKELLHpEPIYVDksDDVN--KIEVEVALQYN-DTYGEILYT 287
37522075  210 -------------GETEr-tESYIYEGGIREYVKYMTREKAALHpDIIFIN--QERD--GVSVECALQWStDVYNDNVLG 271
126179353 231 -------------TGDV---VTYCFEDGIRQFVAHLGEGKESLHdDIIYFQkrDSES--KVEVEVALQYN-NSYSETIYT 291
154151176 283 ------------gDs-----ATYCYAGGLSEFVKYLNEGNEVLHpNPIYIT--KKDAenKLDLEVAMQYT-TGYDEKLYT 342
219851686 240 -------------SGDK---DEFHYDGGLREFVQYLIDGREVLHpDVIDLSrkDEEN--KLEVEVALQYT-QSYTETVYT 300
25026562  316 FANTINTFEGGTHEEGFRSALTSLMNRYAREHKLLKE-Ke-ANLTGDDCREGLSAVISVRVSEPQFEGQTKTKLGNTEIK 393
86606189  273 FANNIRTTEGGTHLEGLKTALTLTINSQARKLNKLKD-Sd-SNLAGENVREGLTAILAVKVPNPEFEGQTKTKLGNTEVR 350
86607821  273 FANNIRTNEGGTHLEGLKTSLTLTINSQARKLNKLKD-Sd-SNLAGENVREGLTAIVSVKVPNPEFEGQTKTKLGNTEVR 350
81301300  277 FANNIRTIDGGTHIEGLKTVLTRTMNTIARKRNKRKD-Ad-NNLSGENIREGLTAIVSVKVPDPEFEGQTKTKLGNTEVR 354
56751624  277 FANNIRTIDGGTHIEGLKTVLTRTMNTIARKRNKRKD-Ad-NNLSGENIREGLTAIVSVKVPDPEFEGQTKTKLGNTEVR 354
124485239 288 YVNSVNTREGGTHLEGFRSALTRAINNIAHANKHLKEd---VSVRGEDVREGLTAVISVKIANPQFEGQTKMRLGNSNVK 364
37522075  272 FANNIRTIDGGTHLEGLKAVLTRTFNSFARKANKLKD-Gd-KNLTGEHVREGLTAVLSVKVPNPEFEGQTKTKLGNPEVR 349
126179353 292 YVNSVNTREGGTHLEGFRSALTRAINSAAHRNNLLKN-Nd-AQVKGEDVREGLACVISTRVANPQFEGQTKMRLGNSNVR 369
154151176 343 YVNSVNTREGGTHLEGFRSAITRGINVVAKRNGIIKE-NaqVTLRGEDVREGLTSVVSVKMANPQFEGQTKMRLGNSSVK 421
219851686 301 FVNSVNTREGGTHLEGFRSAITRAINNSARKANLIKNnT--LTLRGEDVREGLTAVISIKLANPQFEGQTKMRLGNSNVR 378
25026562  394 SFVQRMANEHIGHWLEANPAEAKVIINKAVGSAQARLAARKARDLVRRKSATDLGGLPGKLADCRSKDPEKSELYIVEGD 473
86606189  351 GIVQTLVSEALTEYLEFNPNVARGIVEKAIQSFNAAEAARRARELVRRKSALESSTLPGKLADCSCRDPAESEVYLVEGD 430
86607821  351 GIVQTLVSEALTEYLEFNPNVARGIVDKAIQSFNAAEAARRARELVRRKSALESSTLPGKLADCSCRDPAESEVYLVEGD 430
81301300  355 GIVDTLVGETLTEYLEFHPSVADLILEKAIQAFNAAEAARRARELVRRKSVLESSTLPGKLADCSSRDPGESEIFIVEGD 434
56751624  355 GIVDTLVGETLTEYLEFHPSVADLILEKAIQAFNAAEAARRARELVRRKSVLESSTLPGKLADCSSRDPGESEIFIVEGD 434
124485239 365 GLVDSMMYQALTEFFEENPKVIAAIAKKSLDAANAREAARRAKELARRKTSLEMSGLPGKLADCSERDPAKSEIYIVEGD 444
37522075  350 GIVDGVISEKLTEYLEFHPDVVASILEKALQSMQAEEAARKARDLVRRKSALESSTLPGKLADCQSRDPAESEVFLVEGD 429
126179353 370 GIVDSLVYSSLTEYFEEHPKTLQTVVDKAMAAARAREAARTARELARRKSTLESTGLPGKLADCQERDPAKSELYIVEGD 449
154151176 422 GIVDSLVYAALTEYFDENPGVLKIIVEKALSAAKAREAARNARDLARRKSSLESAGLPGKLSDCSERDPAKSEIYIVEGD 501
219851686 379 GIVDSLVYQSLSEYFEENPKSIAAIFEKATVAAQAREAARNARELARRKSTLESSGLPGKLADCSERDPAKSEVYIVEGD 458
25026562  474 SAGGSAKSGRDSMFQAILPLRGKILNVEKARLDKVLKNSEVQAIITALGTGIHDE-FDINKLRYHKIVLMADADVDGQHI 552
86606189  431 SAGGSAKQGRDRQFQAVLPLRGKILNIEKADPAKIYKNAEIQAMITALGLGVKGEeFDPSQLRYHRIILMTDADVDGSHI 510
86607821  431 SAGGSAKQGRDRQFQAVLPLRGKILNIEKADPAKIYKNAEIQAMITALGLGVKGDeFDPSQLRYHRIILMTDADVDGSHI 510
81301300  435 SAGGSAKQGRDRRFQAILPLRGKILNIEKTDDAKIYKNTEIQALITALGLGIKGEeFDASQLRYHRIVIMTDADVDGAHI 514
56751624  435 SAGGSAKQGRDRRFQAILPLRGKILNIEKTDDAKIYKNTEIQALITALGLGIKGEeFDASQLRYHRIVIMTDADVDGAHI 514
124485239 445 SAGGSAKQGRDRKFQAILPLRGKILNVEKALEHKALKNAEIQTLITAIGAGYGDK-FDAERARYHHIVIMTDADVDGAHI 523
37522075  430 SAGGSAKQGRDRRFQAILPLRGKILNIERADDRKIYGNNEIQAMITGLGLGLKTEeFDVGRLRYHRIIIMTDADVDGAHI 509
126179353 450 SAGGSAKQGRDRKFQAILPLRGKILNVEKASEHKILKNAEIQALISAIGTGVGDS-FDAERARYHRIILMTDADVDGAHI 528
154151176 502 SAGGSAKQGRDRKFQAILPLRGKILNVEKAGEHQILKNAEIQTLINAIGTGIGEK-FDPERARYHRIVIMTDADVDGAHI 580
219851686 459 SAGGSAKQGRNRRFQAILPLRGKILNVEKATQHKMIKSVEIQVLISAIGAGIGDR-MDANRARYHHIVLMTDADVDGAHI 537
25026562  553 ATLLLTLLFRFMPDLIAEGHVYLAQPPLYKLKW---QRGepgFAYSDEERDQQLEeglaagrkinkddGIQRYKGLGEMN 629
86606189  511 RTLLLTFFYRYQKALLEQGYVYIACPPLYKIEWg-rNNVr--YCYNEAEKEQVLRslpa-----ntkyTIQRFKGLGEMM 582
86607821  511 RTLLLTFFYRYQKALLEQGYVYIACPPLYKIEWg---RNnvrYCYSDAEKDQILRglpa-----nakyTIQRFKGLGEMM 582
81301300  515 RTLLLTFFYRYQRSLLEQGYIYIACPPLYKLERgrnHY----YCYNERELQERIAtfpe-----nanyTIQRFKGLGEMM 585
56751624  515 RTLLLTFFYRYQRSLLEQGYIYIACPPLYKLERgrnHY----YCYNERELQERIAtfpe-----nanyTIQRFKGLGEMM 585
124485239 524 RILLLTFFYRFMKPLVEMGYIYIAQPPLFRIAKgkqEK----YVYTEEDMRLAIAeyge------kgiSVQRYKGLGEMN 593
37522075  510 RTLLLTFFYRYKRDLVEQGYIYIAQPPLYKISIgggrnidvrYCYSEQEKEAILRglre-----nqkyELQRFKGLGEMQ 584
126179353 529 RTLLLTFFYRYMVGLVENGYIYIAQPPLYRVAKg--RQEq--YVYREEEMREILAewge------kgvSIQRYKGLGEMN 598
154151176 581 RTLLLTFFYRYMRKLIELGYVYIAQPPLFRIAKgke----ekYVYKEAEMQKVSAamgd------kgvSIQRYKGLGEMN 650
219851686 538 QTLLLTFFYRYMPELIERGYVYIAQPPLFRIAKg--KQVr--YVYREEEMQQISAefgd------kgvTVQRYKGLGEMN 607
25026562  630 PNELWETTMDPSVRILRRVDLADAQRADELFSILMGDDVVARRSFITRNAKDV--RFLDV 687
86606189  583 PEQLWETTMNPATRVLKQITIEDAAEADRIFTILMGDAVGPRREFIEAHSAQLdlAALDI 642
86607821  583 PEQLWETTMNPATRTLKQITIEDAVEADRIFTILMGDAVGPRREFIEAHSAHLdlAALDI 642
81301300  586 PQQLWETTMDPETRTMKRVEIEDAAEADRIFTILMGDRVQPRREFIETYGPQLsmAALDI 645
56751624  586 PQQLWETTMDPETRTMKRVEIEDAAEADRIFTILMGDRVQPRREFIETYGPQLsmAALDI 645
124485239 594 AGQLWNTTMNPEFRILKQVRIEDASYANEIFEKLMGDDVMPRKDFIKRHAGEV--KNLDI 651
37522075  585 ADQLWETTMNPETRTLRQVTIEDAAEADRVFNILMGDRVEPRREFIETYGPRLqmADLDI 644
126179353 599 AGQLWSTTMDPANRILKQVKIEDAAYANEIFEKLMGENVDARRDFIRRHAKEV--SNLDV 656
154151176 651 AQQLWDTTMDPENRIFLKVSIEDAYEADEMFKTLMGKDVEIRKNFIMRHAKEV--TNLDI 708
219851686 608 ADQLWETTMNPDTRVLKQIRIEDAGYANEIFEKLMGEDVSARKNFILRHAKEV--TNLDI 665
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