Conserved Protein Domain Family
PRA1

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pfam03208: PRA1 
PRA1 family protein
This family includes the PRA1 (Prenylated rab acceptor) protein which is a Rab guanine dissociation inhibitor (GDI) displacement factor. This family also includes the glutamate transporter EAAC1 interacting protein GTRAP3-18.
Statistics
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PSSM-Id: 460846
Aligned: 166 rows
Threshold Bit Score: 51.751
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002500004  22 MRPRPLTEFF--ARFTPPKSQGKLTSRLKCNIYYYRANYFALLVLSFVVAFFRNPFALFACAMSCLSLLCANdSFaqsmS 99 
XP_004200614  21 SKIRPPQEFFdfRRISKPANFSEAQNRISYNLGYFSANYIAIVSILSIYALVTNLLLLFVIALLGGGIFGISrLR----G 96 
EDK42231      26 SKLRPPQEFFdfRRVSKPANFGEIQQRVSYNLGYFSANYLTLVGALSVYALVTNLLLLFVLGFVILGVFGINkLE----G 101
EMG45492      34 SKLRPPQEFFdfRRISKPANFGEIQQRVGFNLGYFSANYIAIVLALSVYALVTNFLLLFVTVFVLGGIFGINkLN----G 109
Q75B09        34 STMRPPREFFnvRRFSKPQNFGEVQSRVGYNLRYYSTNYTAIVILLFIYTLLTNLLLFFVIVFVVAGFTGINrLQ----G 109 Eremothecium go...
XP_003645615  29 SNVRPPQEFLnlRKVSKPQNFSEVQSRVSYNLRHFSTNYTIIILLLFVYTLFTNLLLFFVIVLLIAGMIGINrLK----G 104
CCK71628      34 ASLRPPQEFFnlRAVSKPANMSEIQQRVSYNLGYYSSNYALVVAMLSLYTLFTNLLLLSVIVFVFVGVWGIGkLQ----G 109
XP_002496545  34 STVRPPQEFFnvKNFSKPQNFAELQSRVSYNVKYYQSNYGIIIGALSVYSLLTNLLLLFVISLVVLGVAGISrLR----G 109
EDO18290      34 STVRPVQEFFnvKNISKPNNFSDVQSRVAYNLKYYSTNYAIVVGLLSIYTLLTNLLLLFVIVFVLLGMTGIGkLQ----G 109
CAR25030      34 ATLRPVQEFLnfKKVSKPQNFGDLQSRVSYNLRYFSTNYALIVGALSIYTLLTNLLLLFVIVFVFFGLYGINkLN----G 109
XP_002500004 100 EKITrtvRkYHPPTaAwmRRnanvaaapsrpyskskvvhicgfqrlHVVAFLCVLSFFMLRSSRAVSTVLWALGMFAVGT 179
XP_004200614  97 EDLV---L-PFGRF-N--TS--------------------------QLYTGLFVVTVPLGFIASPISTMMWLLGSSGFSV 143
EDK42231     102 QDLT---T-PFGNI-T--TS--------------------------QLYTGLLIVAVPLGFLASPVSTLMWLIGLSIVGV 148
EMG45492     110 EDLV---L-PVGRF-T--TS--------------------------QLYTGLLIVAVPLGFLASPISTMMWLIGSSAVTV 156
Q75B09       110 ADLS---T-PFGPI-T--TS--------------------------QLYTGLIGIATVLGIFASPFSTLMWLVGISAVTI 156 Eremothecium go...
XP_003645615 105 SDLV---T-PFGSL-T--TS--------------------------QLYTGLLCVTVPLGFLASPISTLMWLIGISAVIV 151
CCK71628     110 QELT---T-PFGVF-Q--PT--------------------------QLYTALLCVAVPLGFFASPISAMLWLVGASSVTI 156
XP_002496545 110 EDWV---T-PVGTF-K--VN--------------------------QLYTALTCVAVPLGFLASPFTTILWLVGASAVTV 156
EDO18290     110 EDLV---T-PFGTL-K--TS--------------------------QLYTGLICISVPLGFLASPISTLMWLIGASGVTV 156
CAR25030     110 QDLV---L-PFGVL-K--VS--------------------------QLYTALTCIAVPLGFVASPFSTLMWLIGASAVSV 156
XP_002500004 180 LAHASLRSPNLKARL 194
XP_004200614 144 LTHAALMEKPIETVf 158
EDK42231     149 GAHATMMEKPIETVF 163
EMG45492     157 GSHAALMEKPIETVF 171
Q75B09       157 FSHASFLEKPIETVF 171 Eremothecium gossypii
XP_003645615 152 FSHASFMEKPIETVF 166
CCK71628     157 FAHASLMEKPIETVF 171
XP_002496545 157 IGHASFMEKPIQVVF 171
EDO18290     157 IGHASFMEKPIETVF 171
CAR25030     157 LGHASFVEKPIETVF 171
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