4TSK,4XIY,5W3K,6L2I


Conserved Protein Domain Family
IlvC

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COG0059: IlvC 
Ketol-acid reductoisomerase [Amino acid transport and metabolism, Coenzyme transport and metabolism]
Ketol-acid reductoisomerase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Statistics
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PSSM-Id: 439829
Aligned: 419 rows
Threshold Bit Score: 315.074
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4TSK_A         1 MEKI----YYDA---DISIQPLADKRIAVIGYGSQGHAHAQNLRDSGFDVVIGLRP-----GS-SWAKAEADGFRVMAVG 67 
WP_013996712  14 LAQLgvceLLQKsdfSQGVEALKGKKIVIVGAGAQGLNQGLNMRDSGLNVSYALREcaiaeKRpSYTNTIANGFQVGTFE 93 
WP_007634259  14 LDQIgrcrFMQRaefSTGCDFLKGKKIVIVGCGAQGLNQGLNMRDSGLNISYALRQaaideKRdSFQRADGNGFTVGTYK 93 
WP_015488358  15 LDQLgrcrFMDRsefASEAEFLKGKKIVIIGCGAQGLNQGLNMRDSGLDVSYTLRAaaiaeKRqSWKNATDNGFTVGTYE 94 
WP_013855650  14 LDQLgrcrFMDRsefESEAEYLKGKKVVIVGCGAQGLNQGLNLRDSGLDVSYALRQaaideQRqSYKNAKENGFEVGSYE 93 
WP_055733079  14 LEQLgkcrFMDRsefADGCNFIKDWNIVVVGCGAQGLNQGLNMRDSGLNISYALREaaikeKRaSFVQATDNGFKVGTYE 93 
WP_068546270  14 LSQLgkcrFMNRdefSDGCNFIKGWNIVIVGCGAQGLNQGLNMRDSGCNISYALRDaaiseKRqSWQWATENGFTVGNYE 93 
WP_087036528  15 LEQLgkcrFMKRnefADGCDYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRDeaiaeKRqSYKQATENGFKVGTYK 94 
WP_104936011  15 LEQLgqcrFMHAde-fDGVGKLQGKKIVIVGCGAQGLHQGLNLRDSGLDVAYALREeaiktKRqSWKNATDNGFRVGTYE 93 
WP_108602724  15 LDQLgrcrFMERsefENGCEALKGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRGaaiaeKRqSWKNATDNGFTVGTYE 94 
4TSK_A        68 EAVEESDVIMILLPDERQPAVYeREIRPYLTAGKALAFAHGFNIHFSQIQPPKDVDVFMVAPKGPGHLVRRVYEAGGGVP 147
WP_013996712  94 ELVPTADLVCNLTPDKQHTSVI-NKIMPLMKQGATLSYSHGFNIVEEGIEIRKDITVIMVAPKSPGSEVREEYKRGFGVP 172
WP_007634259  94 ELIPTADLVYNLTPDKQHSSVV-EAVMPLMQKGATLGYSHGFNIVEEGQQIRSDITVVMCAPKCPGTEVREEYKRGFGVP 172
WP_015488358  95 ELVPQADLLVNLTPDKQHTDVV-TTVMPMMKQGACLGYSHGFNIVEEGMQIRSDLTVVMVAPKCPGSEVREEYKRGFGVP 173
WP_013855650  94 TLIPQADLVINLTPDKQHSNVV-ETIMPLMKKGAALGYSHGFNVVEEGMQIRKDITVVMVAPKCPGTEVREEYKRGFGVP 172
WP_055733079  94 ELIPQADMVLNLTPDKQHSNVV-ETVMPLMKEGATLAYSHGFNIVEEGMQVRKDITVVMVAPKCPGTEVREEYKRGFGVP 172
WP_068546270  94 ELIPQADLVLNLTPDKQHTSAV-SAVMPLMKQGSTLAYSHGFNIVEEGMQIRKDITVVMVAPKCPGTEVREEYKRGFGVP 172
WP_087036528  95 ELIPTADLVMNLTPDKQHTSAV-NAVMPLMKEGAALGYSHGFNIVEEGMQIRKDITVVMVAPKCPGTEVREEYKRGFGVP 173
WP_104936011  94 EMIPTADLIVNLTPDKQHSKIV-AAIMPLIKKGACLAYSHGFNIVEEGMAIRPDITVIMVAPKGPGTEVREEYKRGFGVP 172
WP_108602724  95 ELIPEADLVCNLTPDKQHTAVV-GAVMPLMKQGATLAYSHGFNIVEEGMQIREDITVIMCAPKCPGSEVREEYKRGFGVP 173
4TSK_A       148 ALIAVH--QDASGQAKDLALAYARGIGAGRAGILTTTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPEIAYF 225
WP_013996712 173 TLIAVHpkNDPENKGFEWAKAYATALGSDTAGVLRSSFVAEVKSDLMGEQTILCGLLQTGSILAFNKMKREGVAPEHAAK 252
WP_007634259 173 TLIAVHpeNDPEGQGWDIAKALASATGGDRAGVLESSFVAEVKSDLMGEQTILCGMQQVAAVLGYEKMIANGIDAGYAGK 252
WP_015488358 174 TLIAVHpeNDPKGEGWDIAKAWAAGTGGHRAGCLESSFVAEVKSDLMGEQTILCGMLQTGAILGFEKMVEDGIDEGYAAK 253
WP_013855650 173 TLLAVHpeNDPQGEGWDIAKAWAAGTGGHRAGCLESSFVAEVKSDLMGEQTILCGMLQAGSIVCYEKMVAEGIDPGYAGK 252
WP_055733079 173 TLIAVHpeNDPQGNGLAIAKAYASATGGDRAGVLESSFVAEVKSDLMGEQTILCGVLQTGAILAYDKMVAEGLDAGYAAK 252
WP_068546270 173 TLIAVHpeNDPQGNGFAIAKAYASATGGDRAGVLESSFIAEVKSDLMGEQTILCGMLQTAAVLGHQQLVAQGMDAAYARK 252
WP_087036528 174 TLIAVHpeNDAKGEGLAIAKAWASATGGDRAGVLESSFVAEVKSDLMGEQTILCGMLQAGAILAHDKMLADGIDAGYAGK 253
WP_104936011 173 SLIAVHreNDPNGEGMDLAKAYACGLGADKAGVLESSFVAEVKSDLMGEQTILCGLLQAASLLCYDKMVQEGVEEGYASQ 252
WP_108602724 174 TLIAVHpaNDPQGHGLEWAKAYASATGGDRAGVLESSFVAEVKSDLMGEQTILCGMLQTGAILGYEKMIAEGADPAYASN 253
4TSK_A       226 ECLHEMKLIVDLIYEGGLEYMRYSISDTAQWGDFTSGPRIInEETKKEMRRILADIQSGAFAKSWILENQANRPMFNAIN 305
WP_013996712 253 LIQYGWESITEALKHGGITNMMNRLSNPAKVRAFAISEDLK-KMMRPLFEKHMDDILSGHFSKTMMEDWANNDKNLLTWR 331
WP_007634259 253 LIQDGLETITEALKIGGVTNMMDRLSNPAKVKAFELSEQLT-ELLRPLFGKHQDDIISGEFSRNMMEDWANGDANLFKWR 331
WP_015488358 254 LIQYGWETVTEALKYGGITNMMDRLSNPAKILAFDMAEELK-ELMRPLFRKHQADIISGEFSSTMMADWANDDKNLLTWR 332
WP_013855650 253 LLQYGWETVTEALKFGGITHMMDRLSNPAKIKAFELSEELK-DLMRPLYNKHMDDIISGHFSSTMMADWANDDADLLGWR 331
WP_055733079 253 LIQFGWETVTEALKHGGITNMVDRLSNPAKIKCFDLADELK-DLMRPLFEKHMDDIIEGEFSSTMMKDWANDDVNLLKWR 331
WP_068546270 253 LLQYGLETTTEGLKHGGITNMMDRLSNPAKIKAFDMSEELK-VILRPLFNKHMDDIIEGQFSATMMEDWKNDDANLLKWR 331
WP_087036528 254 LIQFGWETITEALKQGGITNMMDRLSNPAKIKAFDMAEELK-ELMRPLFNKHMDDIIQGNFSAGMMADWANDDKDLLTWR 332
WP_104936011 253 LVQKGWEVISEALKHGGITNMMDRLANPAKIMAFDLAEQIR-DILTPLFEKHMDDIMSGKFSSTMMADWKNGDRDLLAWR 331
WP_108602724 254 LIQYGWETITEALKYGGITGMMDRLSNPAKIECFALAQELK-DILRPLFYKHMDDIITGHFSKTMMEDWANGDANLLKWR 332
4TSK_A       306 RRELEHPIEVVGRKLRSMMPFI 327
WP_013996712 332 SATAETDFEKTPTTTEAIEEqt 353
WP_007634259 332 EETGQSGFENAPVFEGVIDEQE 353
WP_015488358 333 EETLATGFEKAPASDVAIDEQe 354
WP_013855650 332 AETGETAFENYPQSDVQITEQe 353
WP_055733079 332 EETGQSGFENAPVSDVEITEQE 353
WP_068546270 332 AETAETSFEQAADCDTEITEqe 353
WP_087036528 333 EETADTSFEQYPATDVVIDEQE 354
WP_104936011 332 AETQATAFEKASSADEDISEQE 353
WP_108602724 333 AETAETAFEKSSSEGVEIDEQe 354
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