1UC2,2EPG


Conserved Protein Domain Family
RtcB

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COG1690: RtcB 
RNA-splicing ligase RtcB, repairs tRNA damage [Translation, ribosomal structure and biogenesis]
Statistics
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PSSM-Id: 441296
Aligned: 371 rows
Threshold Bit Score: 283.246
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1UC2_A         5 LKR----------I-----DKI--------RWEIpkfdkR-MRVPGRVYADEVLL------------EkmknDRTLEQAT 48 
WP_015892183   1 MKT----------Il---hGNN--------HREV-----KlEHGNVHVFANDEVFas---------fG----ERVYQMAD 41 
WP_012909315   6 MNQ----------Iia--tGEA--------TAILpa--gD-HVTPVTVIGTE-AIrn--------tfD----EVCIRQAI 49 
WP_013386328   5 VKKh---------------NDA--------HREI-----SlPNGKLHVFANDRVFns---------lE----EKVFEMAD 43 
NP_866886     25 LRRtsamdtmhemLei--tGPA--------TATLpv--gD-GCSPITVIGTD-PIrq--------sfG----SQTFQQAI 78 
NP_868843     16 LYSgp-------gMva--tGEA--------TALLr---tE-TTPPIRVFGTE-SIre--------tfD----DLCLQQAV 61 
WP_014392929   7 LEK----------V-----SEG--------HYVLpr-tkT-MRVHADLFLSDKLLwgeegnpeapplE----DAVFDQVV 57 
WP_053231045   5 MSRdsr-----elIragdwKRHcvwdaeggYHRLet-edV-GDVPVRLFLGDALLre---------cE----QDVYRQIV 64 
WP_075094686   1 --------mlpetIvp--tGDA--------TALLpt--gT-KVPPITVIGTE-AIrg--------tfD----EKCLQQAI 46 
WP_102993244   2 IKHh---------------GNN--------HREL-----SlAHGTLHVFANDEVFas---------lE----QRVYDMAD 40 
1UC2_A        49 NVAMLPGIYKySIVMPDGHQGYGFPIGGVAAFdvkEGVISPGGIGYDINCGVRLIRTNLTEKEV--RPR--IKQLVDTLF 124
WP_015892183  42 NNLRIPRNVY-FSYTPDAHVGVGTCIGTTAVWnlsDGFVSPSIVGSDIGCGMRLHLTPLHRDDL--KDKslKRALIEAIE 118
WP_012909315  50 NSRRAPGVSH-VVLNPDGHLGYGAPIGCVMVS---PSHIYPGPVGVDIKCSMSLLQLDLPADAI--EDRrvRRELIMAVC 123
WP_013386328  44 NNLRIPRNVH-MSYTPDAHVGVGTCIGTTAVWkmsDGFISPSIVGVDIGCGMRVHLTSLHKDQL--QDKqlKRSLIEAIE 120
NP_866886     79 NSRLAPGVSQ-VVLNPDAHVGYGAPVGCVMVS---PTHVYPGPVGVDIKCSMSLLQTDLPESEI--TDWkmRRRVIQAIA 152
NP_868843     62 NSRLAPGVTD-LVLNPDAHCGYGAPVGCVMVS---PTHIYPGPVGVDIKCSMSLLQLDLPAEAI--EDRkvRRALISAIC 135
WP_014392929  58 NAATFPGVTR-VAVTPDCHVGYGVPIGTIVET---DGTLLPTAAGYDIGCGMVQLQTSLTVEDVadPAK--RRQWINEVT 131
WP_053231045  65 NATRFPGVKC-VVITPDVHVGYGVPVGCVILTdrdEGAVAMGPVGFDIGCGMVSARSDAPAEAAt-PDR--QLEFNREVM 140
WP_075094686  47 NSRLAPGVTD-LVLNPDAHCGYGAPVGCVLVS---PSHVYPGPVGVDIKCSMSLLQLDLPADQI--IDRptRRAIINAIC 120
WP_102993244  41 NNLRIPRNVY-MSYTPDAHVGVGTCIGTTAVWnmkDGFVSPSIVGSDIGCGMRVHLTPLTKADI--QSKslRREMIESIE 117
1UC2_A       125 KNVPSGVGSqg---rI-KLH-WTQI-----DDVLVDGAKWAVDNGY--------GWERDLERL-EEGGR-----MEGADP 180
WP_015892183 119 AYVPTNERGn------tHFT-DIRL-----EEVVKHGLQGLPSNYIpdteaapdTFSRSFSHV-EKYTFe----FDHSFL 181
WP_012909315 124 NRIPTGAGRga-----rSVKhGRRVdtdvgRTLLAEGASADVCQAL--------GIPPEWAARcEDSHHvghdgTSVALA 190
WP_013386328 121 KYVPTNERTn------sHYA-SIDL-----QEVVTKGIEGLPSLYk-------eAFEGATSKV-ENAQFe----FDTQYL 176
NP_866886    153 KRVPTGAGRgq-----rHVPkSRSVdgplgFQVATEGASKSVLKKL--------GIPKSWASRcEDASHtapdgSVDTLA 219
NP_868843    136 QRTPTGAGKgq-----rSVTkARHVnrtlgKQLVTEGASDDVCHAL--------GIPTSWSHRcEDSYHvghddTQLALE 202
WP_014392929 132 ERIAVGVGAtrarkqR-RVS-DPTL-----KEVLRHGAKALGRSRS--------VTERDFIPV-EDTGV----------- 184
WP_053231045 141 ERVALGAGGks--hrFgELS-KREL-----EEVVRGGAEHYVEAh---------GARVDRHRA-ERQR------IPVDDG 196
WP_075094686 121 ERTPTGAGRgq-----rHAKkSRFVdetlgRQAVIEGASESVCTQL--------GIPPEWATRcEDSFHvghdgTADALG 187
WP_102993244 118 KYVPVNERQs------sSYS-DIEV-----EKVVTEGIEGLPVSYIpde--kpsKKSRSLTHV-EHAKFk----FDKEYL 178
1UC2_A       181 EAV---S---Q----R-AKQRG---APQLGSLGSGNHFLEVQVV---DKIFDP-EVAKAYGLFEGQVVVMVHTGSRGLGH 242
WP_015892183 182 EQI---P---Q----K-SWSRA---WGQLGTLGGGNHFIEIQHI---EIAEENrEIAKAWGLFDGQVVIMIHSGSRAWGA 244
WP_012909315 191 QRV---EfheEigtfR-DLRSK---LQQIGSYGGGNHFGECEVVqieNNARAR-SVADTFGLRDGCVAFLSHCGSRGIGH 262
WP_013386328 177 EML---P---Q----K-IWKNA---HGQLGTLGGGNHFIELQHV---EIDEANhEVAEKWGLFDGQVIVMIHSGSRAWGA 239
NP_866886    220 ARL---EwmgRerdkRdRLESK---FRQLGSYGGGNHFGEAEIVslsNKQYFR-SLGEQWGLRDGCVAFLSHCGSRGFGH 292
NP_868843    203 NRL---DtilShrhmS-NFSDK---MQQLGSYGGGNHFGECEVVevgDNDRAR-EVAQTFGLRDGNVAFLSHCGSRGFGH 274
WP_014392929 185 ---------------S-IPERAfdkRGQLGSLGGGNHFTEMQVD------------------ETGRVWVMLHTGSRGFGW 230
WP_053231045 197 WKIpwgG---K----G-NPERG---LAQLGTLGGGNHFIELQRS---E--------------QTSTLFVQVHTGSRGFGH 248
WP_075094686 188 QRL---QghlDggffR-NFADK---INQLGSYGGGNHFGECEVVqiaDNDRAR-TAAEVFGLRDGKVAFLSHCGSRGIGH 259
WP_102993244 179 SAV---S---D----K-MWARA---WQTIGTLGGGNHFVEIQTL---EINEAKrDIAAKWGMFDGQVVVMIHSGSRAWGG 241
1UC2_A       243 QVASDYLRIMERAIRKYRiPWP--DRELVSVPFQSEEGQRYFSAMKAAANFAWANRQMITHWVRESFQEVFKqdpeGDLG 320
WP_015892183 245 MLGRDYTKSFKEVMYKWGiHNP--EPSLVYAPIQSEEGQQYLNLMYSALNFAVTNRHMIGFSVEQAFRDIFG----RETR 318
WP_012909315 263 NLAMHQFKTLQSKFAKWDiPLPgnDRELVYAPLGSDEGNAYIDDMSLGANFATLNHLVINLQVLEAFQQVFP-----GVK 337
WP_013386328 240 MLGREYTKLFKEAMEMWGiSNP--DPALMYAPMKSIEGQTYLNLMYSALNFAVSNRHMIAYGVQQGFRDIFG----AEFE 313
NP_866886    293 DWAMSQFRAMKTHFQSSGlAFPagDPQLCYAEADSPEGQRYLCDMAMGANFATVNHLLINQLVLESFREVFP-----GIR 367
NP_868843    275 NLASGQFRTLQDKFDRWGiPLPagDRQLVYAPLGTDEANDYLDDMALGANFATVNHLLINALVLEAFQEVIP-----GTR 349
WP_014392929 231 NIAKHFFVAGA---AQLGlKSR--SEDFVWLDADSALGRSYWNLHNMAANFAVANRLLIGEAVCGALEDVFG----G--T 299
WP_053231045 249 GLATNYFEMARAEHPEQR------DIDLGFFTPDSAHYREYLNAVAAGGNYAIVNRLVLFEAVAEAFRRVFR----K--D 316
WP_075094686 260 NLASGQFKSLQAKFENWSiPLPgeDRELVYAPLGTPEADAYLDDMALGANFATINHLLINALVLEAFQEVIP-----GVT 334
WP_102993244 242 MMGKQYTRDFRNAMDLWGiENP--DPTLVYAPIQSAEGQRYINLMYSALNYAVVNRHMIAFGVRQGLKDVFG----SAFE 315
1UC2_A       321 MDIVYDVAHNIGKVEEhevdGKrvKVIVHRKGATRAFPPGHEA---VprlYRDVGQPVLIPGSMGTASYILAGT-EGAmk 396
WP_015892183 319 TPVLYDLMHNYALKESh--rNT--PVLVHRKGATKALPAGHFQn-pKa--YRKTGHPALIPGSMGTSSYIMVGSeAGA-- 389
WP_012909315 338 GDLVYFISHNIAREEVv--eNR--KAWVHRKGATRAFPAGHHAlkgTp--YENTGHPILLPGNPQAGSAVMVADaGAA-- 409
WP_013386328 314 MPVLYDLMHNYALKEFh--rNQ--AMLVHRKGATRALPKGHFLn-vPa--YKETGHPALIPGSMATASYIMLGQdAGQ-- 384
NP_866886    368 GELIYFISHNIARQEPv--dGR--LQWVHRKGATRALPKGHEQlagTe--FESTGHPILLPGNPRDGSSIMVAQrGAS-- 439
NP_868843    350 GNLVYFISHNIARKEIv--dNQ--PAWVHRKGATRAMPGGHHSlanTp--FAKSGHPILLPGNPRDGSAVMVADeGAS-- 421
WP_014392929 300 ANIYYEISHNLIQREG--------GKFVARKGATRAFPAGHPAlkgTt--WEATGHPILIPGSMETGSAILFAEpGAE-- 367
WP_053231045 317 LELIYEISHNLVQAEThpefG---KVWVHRKGATRAFPGGHPAlrgTe--WEASGHPVLIPGSNRDWSYILRPKpGAV-- 389
WP_075094686 335 GELVYFISHNIARQEIv--gNR--LSWVHRKGSTRAFPGGHPAlkgTl--YESTGHPILLPGNPQAGSCVMVADdGAA-- 406
WP_102993244 316 MPVLYDLMHNYALQEFh--rNR--AMLVHRKGTTRALPAGHFLn-aKp--YKETGHPALIPGSMGTASYIMVGEkAGE-- 386
1UC2_A       397 ETFGSTCHGAGRVLSRKAATRQyRGDRIRQEL---LNRGIYVRAASMRVVAEEAPGAYKNVDNVVKVVSEAGIAKLVARM 473
WP_015892183 390 KNFYSICHGAGRVRSRKATKELvTIDQFEQAMrvgQEDEIMVNHRSLASILDECPQAYKDVDQIIDSVVGANLASVVAKC 469
WP_012909315 410 LSCFSVNHGAGRVLGRKAAIRAlDQQSIDKSF---DDHDI--LTNCRQYPKDEAPAAYKDFEEVLRSVKLAGLASEVARL 484
WP_013386328 385 KNFYSICHGAGRVRSRRATKELiTIDQVAQSMrvgEDDEILVNHRTLEGLVDESKYAYKDVDQIIDSIVESGLANVVAKC 464
NP_866886    440 VSAFSVNHGAGRQLSRTKAKKNlNQTVIDQNL---LDHDV--ISNCRVYPRDEAPDAYQDFAEVLKSVTKAGLADEVARL 514
NP_868843    422 ASCYSVNHGAGRTLGRRHAKRVlDQATVDSEF---DSNDI--LSNCRKYPIDEAPAAYKDFNEVLRSVKSAGLASEVARL 496
WP_014392929 368 KSIYSVNHGSGRRLSRAAARRQlQQEETDRRM---AEAGILLN--TRTTPLDESGPCYKNLDDVLETVEQAGLARVAHRL 442
WP_053231045 390 KSAYSVNHGAGRRLSRGEATRTlDQQKIDEQY---RRDGILVNL-DGRVPLDEAAPCYKSSDEVVSAVVAAGLAEIEHRL 465
WP_075094686 407 LSCYSVNHGAGRVLGRKRAIRElDQRSIDQSF---DEQDI--LTNCRTYPKDEAPAAYKDFNEVLRSVNQAGLATEVARL 481
WP_102993244 387 KNFYSICHGAGRVRSRKATKQVvTIDQFAQSMrvgTEEEIMVNQRTLRDILDECPQAYKDVDQIIDSVVGAGLASVVAKC 466
1UC2_A       474 RPIGVAKG 481
WP_015892183 470 NPLIAIKG 477
WP_012909315 485 KARFVIKD 492
WP_013386328 465 NPLAVIKG 472
NP_866886    515 KAKFVLKD 522
NP_868843    497 KARFVIKD 504
WP_014392929 443 KPVACIKG 450
WP_053231045 466 WPVCSLKG 473
WP_075094686 482 KARFVIKD 489
WP_102993244 467 HPMAVIKG 474
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