Akirins are small, highly conserved eumetazoan nuclear proteins that play a role in immune response and tumorigenesis. It is believed that they act as a connector between a variety of transcription factors and major chromatin remodeling complexes. In vertebrates, there are two orthologs, Akirin1 and Akirin2.
Jiyao W et al.(2023). "The conserved domain database in 2023.",