4DN9,4NPO,1X7V,1Y0H,3BM7,3MCS,4OZ5,4NL5,2GO8,3FGV,1TUV


Conserved Protein Domain Family
ABM

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pfam03992: ABM 
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Antibiotic biosynthesis monooxygenase
This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.
Statistics
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PSSM-Id: 427635
Aligned: 86 rows
Threshold Bit Score: 41.4864
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4DN9_B  24 YGLIGKXR-ATPGQRDALIAILVEGAS----SXPGCLSYVVAQdPKDPDAIWITEVWDS---PES-HKASLSL------- 87  Chloroflexus aurantia...
Q8NRX5   2 HIVNIRFK-PKAKYVDTFRYTVDKFTEst-rTEEGCLYFDWFRnTDYPGEYLVIGVWTD---EGA--TEHKKS------- 67  Corynebacterium gluta...
Q8NRX6   2 ILINVKFK-PLPEYVDTFREQVAEFTEkt-rAEEGNIFFDWSInTDNPNEFILIEAFQD---DAA--EAHVNS------- 67  Corynebacterium gluta...
O06569   2 IFIVVKFE-TKPEWTERWPDLVASFTAat-rAEEGNLWFEWSRsLDDPAEYVLVESFRD---GEA-GGVHVNS------- 68  Mycobacterium tubercu...
Q97V29   2 INVGFYYK-VKRGFEKDFENKFKEVLSylraNADGFVDAKLYKnVDEPSEYLIYSVWRD---LDS-FKKFVSS------- 69  Saccharolobus solfata...
Q9HNN4 402 GTMGMFYE-TKPEHTAEFVEKFDTVAGvl-aDMDGHFDTDLMVnVENDDDMFIASQWRS---QED-AMAFFRS------- 468 Halobacterium salinar...
Q9RTW6  24 VLEIAMLN-VRPGQTAEFEAAFAQAGRli-aSIPGYRRHELQRcLEDAHKYVLLVWWDT---LEAhTVGFRGS------- 91  Deinococcus radiodurans
O31484   2 VREAAMLH-IKEGLEQEFEDAFRQAAPii-sGMKGYITHSLSKcMEETHKYLLLVEWET---LEDhTEGFRGS------- 69  Bacillus subtilis sub...
3FGV_B  14 REVVIVKStPQRGKFNAFAELVGKLVSet-rDFPGCLGAYLXL-APERNEQVVXHIWETpdaLEAyLTWRADR------- 84  Ruegeria pomeroyi DSS-3
Q9X9W3 129 VIVDIEFEgPDPDRQRAWVDAVFEALEsephPHPGGISAHFHLsTDGTR-VLNYAEWES---AQA-HLDALAApgdgvgs 203 Streptomyces coelicolor
4DN9_B  88 --PSVQDAI 94  Chloroflexus aurantiacus J-10-fl
Q8NRX5  68 --EHFLRAQ 74  Corynebacterium glutamicum
Q8NRX6  68 --DHFKAAC 74  Corynebacterium glutamicum
O06569  69 --DHFRQAM 75  Mycobacterium tuberculosis
Q97V29  70 --SAYKNTV 76  Saccharolobus solfataricus
Q9HNN4 469 --DDFGDTV 475 Halobacterium salinarum NRC-1
Q9RTW6  92 --AEYGQWR 98  Deinococcus radiodurans
O31484  70 --SEYQEWK 76  Bacillus subtilis subsp. subtilis str. 168
3FGV_B  85 --GDFLEIN 91  Ruegeria pomeroyi DSS-3
Q9X9W3 204 ttPQWERVQ 212 Streptomyces coelicolor
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