Conserved Protein Domain Family
DUF2462

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pfam09495: DUF2462 
Protein of unknown function (DUF2462)
This protein is highly conserved, but its function is unknown. It can be isolated from HeLa cell nucleoli and is found to be homologous with Leydig cell tumour protein whose function is unknown.
Statistics
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PSSM-Id: 462817
Aligned: 98 rows
Threshold Bit Score: 32.2357
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGF81295       1 MVQGQKKPKSV------L---ASKSTKKSNEHHRG-KRVAPKSAGIIKQKSIQKKLASANIKNTESLMAVRAGATg--KL 68 
5_pfamImport   1 MPQGIKKNKNPpl--pgI---TKKKKDKVQSLSRKsRPIAPKKVKNAEVQHLKKVITKNVNKCMEEQIRSIANDSq--KV 73 
XP_001946410   1 MPQGKFKNKSQv-----S---FSKKKRNEPNKSRKaCPMPSKKHKYEEGQRIKRMISKNVNKMAEDELRSLAMDNk--KV 70 
XP_011053964   1 MAQGKLKVKTKlptsvkTkanKGKGKKGPAIQKRGnAPVQPKKAKLQEAQKLKKMISKTVNTVVEDEIREKALEG---RK 77 
XP_011153992   1 MAQGKLKVKTKlpdkvkAkv--nKGKKGPAIQRRGnAPVQPKKAKLQEAHKLKKMITKTVNSTMEDELRKRALDG---KK 75 
EFN60442       1 MAQGKLKVKTKlpasvkTka--nKAKKGPAIQKRGnAPVQPKKTKLQEVQKLKKVISKAVNSTIEDELRERALEG---KK 75 
EDW41350       1 MPQGKFK-KAKlpaaiqKkk----nQKQAAFTRRSnAPIQAKKAKFNETQKIKSVISKSVNKSVESELRSRAHEG---YI 72 
XP_001869485   1 MAQGKLKVKSKppvnnkKaa----nNKGSAFSKRKnAPIQSKKHKIKEDAKLKLAVSRTVNEKNEADIRKLVYEG---QK 73 
Q7PYY2         1 MAQGKLKVKSKqppnakKaa---nKKKGTAFNKRKnAPIQSKKHKFEEAHKLKQVITKTVNKKNEDDIRKVAYEG---QT 74  Anopheles gambi...
XP_011440260   1 MAQGKFKSKGSlpkgvkG---KQSHKHKNSGPKRGaRVIAPKKTKQIEANKIKKGLERSIKANIEHETAMKAQSVepkHF 77 
EGF81295      69 TILKDVA 75 
5_pfamImport  74 HLSKKKD 80 
XP_001946410  71 FLSKKKK 77 
XP_011053964  78 TLTKKNp 84 
XP_011153992  76 SLIKKNp 82 
EFN60442      76 TLVKKNT 82 
EDW41350      73 QLSKAQE 79 
XP_001869485  74 NMSQAQe 80 
Q7PYY2        75 KLSQAQL 81  Anopheles gambiae str. PEST
XP_011440260  78 RVVKSSA 84 
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