16124386 36 APHASAPDcapassdipqqdggstnghghDLKGHGFFALALGSVGVVFGDIGTSPLYAFKEALAAASHD-GVTRSEIFGV 114 Caulobacter crescen... 19551942 5 MKSARPKS---------------------VAPKSGQALLTLGALGVVFGDIGTSPLYSLHTAFSMQHNKvEVTQENVYGI 63 Corynebacterium glu... 15672606 1 MGQVHLHN---------------------RSFNKATSAGFLIALGIVYGDIGTSPLYAMQAIVRGQGGLaNLSESFILGA 59 Lactococcus lactis ... 15672605 1 MG--YESN---------------------RSFNKATGAGFIIAMGIVYGDIGTSPLYTMESIVQGQGGLeRISETSIIGA 57 Lactococcus lactis ... 20091997 1 ------------------------------MFSKSDFRGIINSMGLVFGDIGTSPIYTLTVIFLLTRP---T-EVHVIGV 46 Methanosarcina acet... 16767164 1 ------MS---------------------TDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGf-GVERDAVFGF 52 Salmonella typhimur... 15601289 1 -------M---------------------KPAKQTTASLAFLAMGIVYGDIGTSPLYAFKEVFFSHHPl-AINPDNVLGI 51 Vibrio cholerae 16120359 1 ------MS---------------------TEHKQYLSAVTLAAIGVVYGDIGTSPLYTLRECFSGHYGf-DVRPDVVFGF 52 Yersinia pestis 15804347 1 ------MS---------------------TDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGf-GVERDAVFGF 52 Escherichia coli O1... 16131615 1 ------MS---------------------TDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGf-GVERDAVFGF 52 Escherichia coli K12
16124386 115 VSLALWALILIVTIKYVVFIMRADNKGEGGVLSLMALAQHAMG--KRTTLVFVLGVAGAALFYGDAVITPAMSVLSAVEG 192 Caulobacter crescen... 19551942 64 ISMVLWTITLIVTVKYVMLVTRADNQGQGGILALVALLKNRGH---WGKFVAVAGMLGAALFYGDVVITPAISVLSATEG 140 Corynebacterium glu... 15672606 60 VSLVIWTLTLITTVKYVLIALKADNHHEGGIFSLFTLVRRMRK------WLIIPAMIGGATLLADGALTPAVTVTSAIEG 133 Lactococcus lactis ... 15672605 58 LSLIIWTLTLITTVKYVWIALKADNNHEGGIFSLFTLVRKYAK------WLIIPAMIGGAALLSDGALTPAVTVTSAIEG 131 Lactococcus lactis ... 20091997 47 LSLIIWTLITLVTVEYAWLAMSLGKKGEGGTIVLKELLVPLIKsgRNAAFITLLAYIGVSFLVGDGVITPAISILSAVEG 126 Methanosarcina acet... 16767164 53 LSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSa-RTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEG 131 Salmonella typhimur... 15601289 52 LSLVFWAFVLIVSIKYLLLVTRADQNGEGGILTLSAIAQQSAPk-PWQRIAMLLGILATGFFFGEAVITPAMSVLSAVEG 130 Vibrio cholerae 16120359 53 LSLIFWMLILVVSVKYLTYVMRADNAGEGGILTLMSLAGRNTSs-RATSILVVLGLIGGSFFYGEVVITPAISVMSAIEG 131 Yersinia pestis 15804347 53 LSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSa-RTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEG 131 Escherichia coli O1... 16131615 53 LSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSa-RTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEG 131 Escherichia coli K12
16124386 193 LRTIPALEHgv--tnEVVLLIATVMLLGLFFIQSRGTASVGKLFGPVCAVWFGVMFSLGLMNLAANPGILMAISPYYAVE 270 Caulobacter crescen... 19551942 141 LTVISPSFE------RFILPVSLAVLIAIFAIQPLGTEKVGKAFGPIMLLWFVTLAGLGIPQIIGHPEILQSLSPHWALR 214 Corynebacterium glu... 15672606 134 LRGVTHVYSn----qTAVMVTTLIILAFLFLIQRFGASLVGRLFGPIMFIWFGFLGVSGLINSFLDLSILKAINPYYAIH 209 Lactococcus lactis ... 15672605 132 LRSIPAFHEafgqqqLPIVIITLAILAVLFLIQRFGTSIVGKVFGPVMFIWFSFLGITGLINLFGDFSVLQAINPYWAIH 211 Lactococcus lactis ... 20091997 127 LRIIPDFQDig---qGAIMFIAGIIAVALFSVQSKGTEEITWVFGPVMVLWFASLAFSGIASIFYTPGVLRAINPYYAIS 203 Methanosarcina acet... 16767164 132 LEIVAPQLD------TWIVPLSIIVLTLLFMIQKHGTGMVGKLFAPIMLTWFLILAVLGLRSIIANPEVLHALNPVWAVR 205 Salmonella typhimur... 15601289 131 IAVAQPDLA------PYVLPIAMMIIVALFAVQAMGTERIGRFFAPVMLLWFLVLALLGAHAIWHAPQVLRALNPAYAVH 204 Vibrio cholerae 16120359 132 LEIAAPALD------PYIVPCSIAVLTLLFVIQKHGTGSVGKLFAPVMLVWFLTLALLGLRSIIANPEVLAALNPKWAIS 205 Yersinia pestis 15804347 132 LEIVAPQLD------TWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANQEVLYALNPMWAVH 205 Escherichia coli O1... 16131615 132 LEIVAPQLD------TWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVH 205 Escherichia coli K12
16124386 271 FLAE-HGLTGFIVLGAVFLTVTGVEALTADMGHFGRWPIQAAWLFFVLPCLAMNYLGQGAFALTTLETAQAAgkampeln 349 Caulobacter crescen... 19551942 215 LIVA-EPFQAFVLLGAVVLTVTGAEALYADMGHFGARPIRVAWFCVVMPALILTYLGQGALVINQPEAVRNP-------- 285 Corynebacterium glu... 15672606 210 LLFSpENKAGFFILGSIFLVTTGAEALYSDLGHVGRGNIYVSWPFVKI-CIILSYCGQGAWLLAHRGEHIEKln------ 282 Lactococcus lactis ... 15672605 212 LLLSpENKAGIFVLGSVFLATTGAEALYSDLGHVGRGNIHVSWPFVKV-CIILSYCGQGAWLLQNRGKSLGDin------ 284 Lactococcus lactis ... 20091997 204 FLLH-NGFTGFFVLSEVILCATGGEALYADMGHLGREPILKAWRLVFS-ALVLNYLGQGAFIIRNPESKNI--------- 272 Methanosarcina acet... 16767164 206 FFLE-YKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLVLNYFGQGALLLKHPEAIKNP-------- 276 Salmonella typhimur... 15601289 205 FVLL-YGQHTLFILGLVVLSVTGVEALYADMGHFGIKPIRIAWFALVMPSLLLNYFGQGAYLLTLSAPTGST-------- 275 Vibrio cholerae 16120359 206 FFVE-YKSVSFFALGAVVLAITGVEALYADMGHFGKFPIRLAWFTVVLPSLVLNYFGQGALLLKNPEAIKNP-------- 276 Yersinia pestis 15804347 206 FFLE-YKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP-------- 276 Escherichia coli O1... 16131615 206 FFLE-YKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP-------- 276 Escherichia coli K12
16124386 350 wFFEMAPEAL---RLPLVLLAGAATVIASQAVITGAFSLTQQAIQLGLLPRLDVRRTSETQSGQIFVPQLNTMLLLGVLA 426 Caulobacter crescen... 19551942 286 -MFYLAPEGL---RIPLVILATIATVIASQAVISGAYSLTKQAVNLKLLPRMVIRHTSRKEEGQIYMPLVNGLLFVSVMV 361 Corynebacterium glu... 15672606 283 pFFAVLPDNM---VIYVVILSTLAAIIASQALISGSFTLVSEAIRLKLLPLFKIYYPGQT-LGQLYIPAVNFALWVTTSF 358 Lactococcus lactis ... 15672605 285 pFFAVLPQNL---IIFSVILATLAAIIASQALISGSFTLVSEAIRLKLLPRLRIFYPGET-FGQLYIPAVNLGLWLAASF 360 Lactococcus lactis ... 20091997 273 -LFEMINQQAeviYIPFLILSITATIIASQAMISGMFSIVYQGITTRIIPMLKIDYTSGKLRSQIYIGAVNWLLLISVLF 351 Methanosarcina acet... 16767164 277 -FFLLAPDWA---LIPLLILAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWLLYFAVVV 352 Salmonella typhimur... 15601289 276 -FFSLAPKAW---LWPLILLATFATVIASQAVISGIFSLARQAINYGYLPPMKIAHTSEHSQGQIYVPAANMLLFVAVIF 351 Vibrio cholerae 16120359 277 -FFLLAPDWA---LIPLLILATLATVIASQAVISGVFSLTRQAVRLGYLPPMRIIHTSEMESGQIYIPVINWTLYLAVVL 352 Yersinia pestis 15804347 277 -FFLLAPDWA---LIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVI 352 Escherichia coli O1... 16131615 277 -FFLLAPDWA---LIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVI 352 Escherichia coli K12
16124386 427 IMFTFQTSSALAHAYGLAVTGTMIVTTCMAFIVMRKLWKWSMPMALLFLVPFLALDITFLSANALRFFSGGWLPVLIGAA 506 Caulobacter crescen... 19551942 362 VVLVFRSSESLASAYGLAVTGTLVLVSVLYLIYVHTTWWKTALFIVLIGIP----EVLLFASNTTKIHDGGWLPLLIAAV 437 Corynebacterium glu... 15672606 359 FVLYFKTSEHMEAAYSLAITITMLMTTTLLTYFLIQKG-TPKIAIAIISIGLFCIEGSFFAASLVQFINGAYIVVLIALA 437 Lactococcus lactis ... 15672605 361 IVVYFQSSAHMEAAYGLAITVTMLMTTTLLTVYLSHYQKVKKVLVGLFFTVFIFIEGLFFAASAVKFMHGGYVVVIIAAM 440 Lactococcus lactis ... 20091997 352 MIFEFRDSHRLAAAYGLAVTGTMSITGLMMTLIFYLKGRMFRSFVSLFVTV---IDVVFLLSNTYKIPHGGYWSIVIAAI 428 Methanosarcina acet... 16767164 353 VIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARKNWHWNKYFVALILIAFLCVDIPLFSANLDKLLSGGWLPLSLGLI 432 Salmonella typhimur... 15601289 352 VMLRFRSSANLAAAYGIAVTAIMMISSLLLVLVARYQWQWRWPRVVTIGIVFIGMDSLLLASTSTKLMEGGWLPLLLGCV 431 Vibrio cholerae 16120359 353 VIIGFERSSNLAAAYGIAVTGTMVITSILFCTVAWKNWHWNRFLVVFLLMVLLIIDIPMFSANVLKLFSGGWLPLSLGLV 432 Yersinia pestis 15804347 353 VIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTV 432 Escherichia coli O1... 16131615 353 VIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTV 432 Escherichia coli K12
16124386 507 LFTIMATWVRGSQILTDKTRRDSLP-VADLMDILR---ARAPHRAPGT-AIFLTSDPD--MTPVALMHNLKHNK-VLHER 578 Caulobacter crescen... 19551942 438 LIVVMRTWEWGSDRVNQERAELELP-MDKFLEKLDqphNIGLRKVAEV-AVFPHGTSD--TVPLSLVRCVKDLK-LLYRE 512 Corynebacterium glu... 15672606 438 IIFVMFIWNKSHKIVMKYIKSLNINeYKNQLNALR---HDESYDLYQTnVVYLTSKMDheWIDRSILYSILDKRpKRAEC 514 Lactococcus lactis ... 15672605 441 ILFVMAIWHKSDQLFYKYLNSSNLNdYKEQMDKLR---KDETYDLYHTnVVYLTAKMDkeWIDRSILYSILDKRpKKAKV 517 Lactococcus lactis ... 20091997 429 AFSLIIIYTSGQKKLYELMNPMKIG--D-FLEKYKq-vYASENKISGT-ALFFARDIN--YVPRYISNVMFENN-IIYED 500 Methanosarcina acet... 16767164 433 MFTIMTTWKSERFRLLRRMHEHGNS-LEAMIASLE---KSPPVRVPGT-AVYMSRALS--VIPFALLHNLKHNK-VLHER 504 Salmonella typhimur... 15601289 432 VFIVMYIWQQQRQRLL-EIAGNELS-VSAMIQSLE---EESFQRAAGT-AVYLSRSLN--HVPRSLLHNIKYNK-TLHER 502 Vibrio cholerae 16120359 433 MFIIMTTWKSERFSLLRRMHEHSNS-LEAMIASLE---KSPPVRVPGT-AVYMSRAMN--VIPFALLHNLKHNK-VLHER 504 Yersinia pestis 15804347 433 MFIVMTTWKSERFRLLRRMHEHGNS-LEAMIASLE---KSPPVRVPGT-AVYMSRAIN--VIPFALMHNLKHNK-VLHER 504 Escherichia coli O1... 16131615 433 MFIVMTTWKSERFRLLRRMHEHGNS-LEAMIASLE---KSPPVRVPGT-AVYMSRAIN--VIPFALMHNLKHNK-VLHER 504 Escherichia coli K12
16124386 579 NVILTVRTAETPRVSEEERVKIEKVNDD---FKKVVVNYGFMESPNIPKALAVCRKQ----G--------LKF----DIM 639 Caulobacter crescen... 19551942 513 IVIVRIVQEHVPHVPPEERAEMEVLHHApirVVRVDLHLGYFDEQNLPEHLHAIDPT---------------------WD 571 Corynebacterium glu... 15672606 515 YWFVNVKVTDEP---YTSEYKVDMMDTDf--IVRVNLYLGFRMRQEVPRYLRTIVTDlmesGrlprqhqhYSItpgrKVG 589 Lactococcus lactis ... 15672605 518 YWFVKVNVTDEP---YTSEYEVDMLGTDf--IVCVNLYLGFHMRQEIPRYLRTIVTNlmesGrlpqqnqtYSItpgrKVG 592 Lactococcus lactis ... 20091997 501 NIFISIIKCESPFG--VKSSFAKDLAKG---LRVFEINVGYME---VIDVVQILKDK----G----------------IQ 552 Methanosarcina acet... 16767164 505 VILLTLRTEDAPYVHNVRRVQIEQLSPT---FWRVVASYGWRETPNVEEVFHRCGLE----G--------LSC----RMM 565 Salmonella typhimur... 15601289 503 NVLMTFQYEAVPRVHPCRRAEIEQVSAS---FWQVVIHIGYQEEPDMAQVMHCCGLK----G--------LYL----HPN 563 Vibrio cholerae 16120359 505 VVLLTMRTDDVPYVHNVERVTIEQLSPT---FWRVVARYGWRETPNVAEIFHRCGLE----G--------LSC----QMM 565 Yersinia pestis 15804347 505 VILLTLRTEDAPYVHNVRRVQIEQLSPT---FWRVVASYGWRETPNVEEVFHRCGLE----G--------LSC----RMM 565 Escherichia coli O1... 16131615 505 VDSVNS-------AHRRRSICP---------------------------------------------------------- 519 Escherichia coli K12
16124386 640 ATSFFLGRRSIV-PSANSGMPLWQDRLFIYLMRNAANPTDFFKIPPGRV-VELG-------AQVTV 696 Caulobacter crescentus CB15 19551942 572 NATYFLSALTLR-SRLPGKIAGWRDRLYLSMERNQASRTESFKLQPSKT-ITVG-------TELHL 628 Corynebacterium glutamicum ATCC 1... 15672606 590 DFRFVVVEEKLMnARQMPGFERFVLQTKAQIKRITASPIRWFGLQFSEVtVETVplvlsdvRNLEI 655 Lactococcus lactis subsp. lactis 15672605 593 DFRFIILEEKLInARQMPGFERFVLQTKEQIKKITASPARWFGLHFSEVtVETVplvlsdvKNLEI 658 Lactococcus lactis subsp. lactis 20091997 553 EKTIFYGIEDIL-----TSNLIWK--VFSVIKKLSPSFVQFYKLPSDKL---HGv-----lTRFEM 603 Methanosarcina acetivorans C2A 16767164 566 ETSFFMSHESLI-VGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRV-IELG-------TQVEI 622 Salmonella typhimurium LT2 15601289 564 ETLFLLSSERLK-VQKLGMWHDLKVWFFIQMSKHALRTSERLNIPPDRL-IEMG-------VYREM 620 Vibrio cholerae 16120359 566 ETSFFMSHESLI-LTKRPWHLFLRGKLFIALSRNALRAPDQFEIPPNRV-IELG-------TQVEI 622 Yersinia pestis 15804347 566 ETSFFMSHESLI-LGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRV-IELG-------TQVEI 622 Escherichia coli O157:H7 EDL933 16131615 ------------------------------------------------------------------ Escherichia coli K12
Jiyao W et al.(2023). "The conserved domain database in 2023.",