Conserved Protein Domain Family
PRK07994
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PRK07994: PRK07994 
DNA polymerase III subunits gamma and tau; Validated
Links
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Statistics
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PSSM-Id: 236138
Aligned: 169 rows
Threshold Bit Score: 733.208
Created: 9-Dec-2010
Updated: 17-Jan-2013
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
145299061   1 MSYQVLARKWRPHTFEQVVGQHHVLTALTNALDQGRLHHAYLLSGTRGVGKTTIARILAKSLNCEQGISSHPCGVCDTCR 80 
53804576    1 MLYQALARKWRPHNFTEVVGQEHVVKALTHALEAGRMHHAYLFTGTRGVGKTTLARILAKALNCEDRQGANPCGRCLICR 80 
54295584    1 MSYLALARKWRPRTFSQLVGQEHINKALINALNQQRLHHAYLFTGTRGVGKTSVARILAKALNCEKGITSEPCLHCDTCI 80 
54298738    1 MSYLALARKWRPRTFSQLVGQEHINKALINALNQQRLHHAYLFTGTRGVGKTSVARILAKALNCEKGITSEPCLHCDTCV 80 
148361067   1 MSYLALARKWRPRTFSQLVGQEHINKALINALNQQRLHHAYLFTGTRGVGKTSVARILAKALNCEKGITSEPCLHCDTCV 80 
296108398   1 MSYLALARKWRPRTFSQLVGQEHINKALINALNQQRLHHAYLFTGTRGVGKTSVARILAKALNCEKGITSEPCLHCDTCV 80 
52842953    1 MSYLALARKWRPRTFSQLVGQEHINKALINALNQQRLHHAYLFTGTRGVGKTSVARILAKALNCEKGITSEPCLHCDTCI 80 
182681665   1 MSYLVLARKWRPKRFAELVGQEHVVRALSNALESGRLHHAFLFTGTRGVGKTTIARIFAKSLNCEQGTSADPCGRCTACL 80 
198283699   2 SAYLALARRWRPQHFDDFVGQEAVVSALRHALDSGRIHHAFLFTGTRGVGKTTLARLLAKCLNCERGVSSNPCGECSACR 81 
218666373   2 SAYLALARRWRPQHFDDFVGQEAVVSALRHALDSGRIHHAFLFTGTRGVGKTTLARLLAKCLNCERGVSSNPCGECSACR 81 

145299061  81 EIDQGNFVDLLEIDAASRTKVEDTRELLDNVQYRPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPPYVKFLLATTDPQ 160
53804576   81 EVDEGRFIDLIEVDAASRTKVEDTRDLLDNVQYAPNQGRYKVYLIDEVHMLSGHSFNALLKTLEEPPPHVKFLLATTDPQ 160
54295584   81 AIEQGRYIDLIEIDGASKTRVEDTRDLLDNIQYAPTNGRFKIYLIDEVHMLSQHSFNALLKTLEEPPSHVKFILATTDPQ 160
54298738   81 AIEQGRYIDLIEIDGASKTRVEDTRDLLDNIQYAPTNGRFKIYLIDEVHMLSQHSFNALLKTLEEPPSHVKFILATTDPQ 160
148361067  81 AIEQGRYIDLIEIDGASKTRVEDTRDLLDNIQYAPTNGRFKIYLIDEVHMLSQHSFNALLKTLEEPPSHVKFILATTDPQ 160
296108398  81 AIEQGRYIDLIEIDGASKTRVEDTRDLLDNIQYAPTNGRFKIYLIDEVHMLSQHSFNALLKTLEEPPSHVKFILATTDPQ 160
52842953   81 AIEQGRYIDLIEIDGASKTRVEDTRDLLDNIQYAPTNGRFKVYLIDEVHMLSQHSFNALLKTLEEPPSHVKFILATTDPQ 160
182681665  81 DIDVGRYIDLLEIDAASNTGVDDVREMIENAQYMPSRGKFKVYLIDEVHMLSKAAFNALLKTLEEPPPHVKFLLATTDPQ 160
198283699  82 SIAAGNFVDLLEVDAASRTRVDETRDLLDNVQYAPTAGRYKAYLIDEVHMLSAHSFNALLKTLEEPPEHVKFLLATTDPQ 161
218666373  82 SIAAGNFVDLLEVDAASRTRVDETRDLLDNVQYAPTAGRYKAYLIDEVHMLSAHSFNALLKTLEEPPEHVKFLLATTDPQ 161

145299061 161 KLPITILSRCLQFHLKSLDQTQIAKQLECVLDQEAQPFEPRALLALAKAADGSMRDALSLTDQALAHGNGSVRLESVLAM 240
53804576  161 KIPVTVLSRCLQFNLKRLTPEQIRAQMAQILASESIDFEPAATKALARAAQGSMRDGLSLLDQAIAHCGGRLTNTGVSAM 240
54295584  161 KLPVTVLSRCLQFNLKHLPAELINQQLQLILQEERLDFEIQALDILARAARGSMRDALSLLDQAITSCETKLLANDVKML 240
54298738  161 KLPVTVLSRCLQFNLKHLPAELINQQLQLILQEERLDFEIQALDILAQAARGSMRDALSLLDQAITSCETKLLASDVKIL 240
148361067 161 KLPVTVLSRCLQFNLKHLPAELINQQLQLILQEERLDFEIQALDILAQAARGSMRDALSLLDQAITSCETKLLASDVKML 240
296108398 161 KLPVTVLSRCLQFNLKHLPAELINQQLQLILQEERLDFEIQALDILAQAARGSMRDALSLLDQAITSCETKLLASDVKML 240
52842953  161 KLPVTVLSRCLQFNLKHLPAELINQQLQLILQEERLDFEIQALDILAQAARGSMRDALSLLDQAITSCETKLLASDVKML 240
182681665 161 KLPVTVLSRCLQFNLKRLDEEQIQRQIAKILTAEQITADDTAIIELSKAADGSLRDGLSLLDQAIAYAGGTLREGAVRDM 240
198283699 162 KLPITVLSRCLQFNLRRLDVPQIQGRLRQIMSLEQVPAEDAALQILSRAADGSLRDALSLLDQAIVHGGGAVRRDGVLAM 241
218666373 162 KLPITVLSRCLQFNLRRLDVPQIQGRLRQIMSLEQVPAEDAALQILSRAADGSLRDALSLLDQAIVHGGGAVRRDGVLAM 241

145299061 241 LGTLDHRHLHQLLEAILRQDAAATMAKITEIATLGPDFDQLHAELEGLLHRVAMAQLLPATVQEQGADAE-SLLQLAQAM 319
53804576  241 LGTVSREPVYGALEALAESRADELLAVSATLAEFSPDYQDVVQQLLAILHQIAIAQFAPDAIRQDDEAE--RVLTLARCL 318
54295584  241 LGHTQQDYALLLLQALAKQEAPIMLALSQQIVAEGGNFQYVLDEILNYLHQITVYQCLGD--NNPLISPKtEIKELAKQF 318
54298738  241 LGHTQQDYALLLLQALAKQEAPTMLVLSQQIIAEGGNFQYVLDEMLNYLHQITIYQCLGD--NNPLISPKaEIKELAKQF 318
148361067 241 LGHTQQDYALLLLQALAKQEAPIMLVLSQQIIAEGGNFQYVLDEMLNYLHQITVYQCLGD--NNPLISPKaEIKELAKQF 318
296108398 241 LGHTQQDYALLLLQALAKQEAPIMLVLSQQIIAEGGNFQYVLDEMLNYLHQITVYQCLGD--NNPLISPKaEIKELAKQF 318
52842953  241 LGHTQQDYALLLLQALAKQEAPIMLVLSQQIIAEGGNFQYVLDEILSYLHQITVYQCLGD--NNPLISPKaEIKELAKQF 318
182681665 241 LGTVDRTQVEVMLAALIAGDGDRLLRVIATLAEFSPDWGGVLEALAEALHRIQVQQLVPSVV---FAGDGlNVALLAEQT 317
198283699 242 LGRSGDDAVLGLIAALVDRDAAQVFAIVGDHLARGMDGPGLLDLVIEGLHRIALAQFLPADPDDDGAE---AVVHLRGRI 318
218666373 242 LGRSGDDAVLGLIAALVDRDAAQVFAIVGDHLARGMDGPGLLDLVIEGLHRIALAQFLPADPDDDGAE---AVVHLRGRI 318

145299061 320 SPEEVQLCYQIVLGGRKDLPWAPDGRTSLEMTCLRMLAFSPRreavhpanlTVLPPSMAGGMGVAPAQlgksrgadSAPT 399
53804576  319 TPEDTQLYYQIALQGQKDLQLAPDPRDGFEMLLLRMLAFRPH---------SAEAAPRIVPTAAAPAM------------ 377
54295584  319 SAEDTQLFYQIGIKGREEMHLAPTLTIGFNMTMLRMYTFKPA---------SHVTTPPLAFEQNNKTC------------ 377
54298738  319 SAEDTQLFYQIGIKGREEMHLAPTLAIGFNMTMLRMYTFKPA-----------------SHVTTPPLA--------FEQN 373
148361067 319 SAEDTQLFYQIGIKGREEMHLAPTLAIGFNMTMLRMYTFKPA-----------------SHVTTPPLA--------FEQN 373
296108398 319 SAEDTQLFYQIGIKGREEMHLAPTLAIGFNMTMLRMYTFKPA-----------------SHVTTPPLA--------FEQN 373
52842953  319 SAADTQLFYQIGIKGREEMHLAPTLAIGFNMTMLRMYTFKPA-----------------SHVTTPPLA--------FEQN 373
182681665 318 QPEVVQLWYQMAINGRHDLHLAPSPRVGFEMAVLRMLAFRPV------------------PVVVPGMV------------ 367
198283699 319 SPLTLQSWYFLLLSARRDFALYPDDRMALEMAFLRVLSFSGS------------ASPDSPPAALPGGE------------ 374
218666373 319 SPLTLQSWYFLLLSARRDFALYPDDRMALEMAFLRVLSFSGS------------ASPDSPPAALPGGE------------ 374

145299061 400 LATAIVAPPAAPgsvsvehtatqmvplvahavLETDEQEMASDALSAplfveqdellreaqqmgyeaqpvmdapsapist 479
53804576  378 --------------------------------------RAPSDTGIR--------------------------------- 386
54295584  378 --------------------------------SLIVDDNTPAQNPIGiepip---------------------------- 397
54298738  374 NKTCSLIIDDNT------------------------PAQNPIGIEPI--------------------------------- 396
148361067 374 NKTCSLIVDDNT------------------------PAQNPIGIEPI--------------------------------- 396
296108398 374 NKTCSLIVDDNT------------------------PAQNPIGIEPI--------------------------------- 396
52842953  374 NKTCSLIVDDNT------------------------PAQNPIGIEPI--------------------------------- 396
182681665 368 ---------------------------------STEGQGQSVNAPLM--------------------------------- 381
198283699 375 --------------------------------NRHPGESLPPTREFVmpe------------------------------ 392
218666373 375 --------------------------------NRHPGESLPPTREFVmpe------------------------------ 392

145299061 480 vvaadeamqhlpsdmavaaeqptevpaeivaesvvepeaapsaassmQSLLGKRNLLRSRLRSepataqapRVAPIKPVA 559
53804576  387 -----------------------------------------------------------------------EPHRAREVT 395
54295584      --------------------------------------------------------------------------------    
54298738  397 -----------------------------------------------PVTKATGNIVAYHQTQ--------SLSTDDKKS 421
148361067 397 -----------------------------------------------PVTKATDNTVAYHQTQ--------SLSTDDKKS 421
296108398 397 -----------------------------------------------PVTKATDNTVAYHQTQ--------SLSTDDKKS 421
52842953  397 -----------------------------------------------PVIKATDNTVAYQQTQ--------SLSTDDKKS 421
182681665 382 -----------------------------------------------------------------------ASVGRNAHG 390
198283699 393 --------------------------------------------atsPLSDHSVPLLSIRSRD--------EVREPSPVA 420
218666373 393 --------------------------------------------atsPLSDHSVPLLSIRSRD--------EVREPSPVA 420

145299061 560 APEGRPVAqpavtppsapwqgaavapvhhsapvtaydelppldaydeggsdyeeylnqgfgesaasasmanvaqtaasga 639
53804576  396 RQAPPPAA------------------------------------------------------------------------ 403
54295584      --------------------------------------------------------------------------------    
54298738  422 ANSGESMNc----------------------------------------------------------------------- 430
148361067 422 ANSGESMNc----------------------------------------------------------------------- 430
296108398 422 ANSGESMNc----------------------------------------------------------------------- 430
52842953  422 ANSGESMSc----------------------------------------------------------------------- 430
182681665 391 ANGYTMSQ------------------------------------------------------------------------ 398
198283699 421 TSGQRDAD------------------------------------------------------------------------ 428
218666373 421 TSGQRDAD------------------------------------------------------------------------ 428

145299061 640 savpaygqaapaqaptrarPNPDDLPPWDLDGTPAAraqvapavSSAAPVMPQAVATSEPAPMVdsvmetidwdelesdn 719
53804576  404 -------------------AEASSSGASPWTTSDAL-------------------------------------------- 420
54295584  398 -----------------------------------------------vtkaTDSTLAYHQTPSLstd------------- 417
54298738      --------------------------------------------------------------------------------    
148361067     --------------------------------------------------------------------------------    
296108398     --------------------------------------------------------------------------------    
52842953      --------------------------------------------------------------------------------    
182681665 399 ---------------------------------------------------SRSDLQKVRVGSL---------------- 411
198283699 429 --------------------------------------------AGTAPAA----------------------------- 435
218666373 429 --------------------------------------------AGTAPAA----------------------------- 435

145299061 720 qpeegeeVARLIPSSLLVNcddPWAELIARTGVGGRLRQLAINSVMTRQGDK-VLLTLKPEQ-RHLVSDRARVDLAEIIG 797
53804576  421 ----------------------NWPRMIEAMRLAGMTRQLASHCVLRTLTEHaCELALDPRQ-AQIHTPTVTSNLETALQ 477
54295584  418 -----dkKSANAGESMSRD----WNDIIPQLKLSGLALNAIENAEFLGKKEReITLGVQKGH-QSLFTPTTINRIETALA 487
54298738  431 ----------------------DWNDIIPQLKLSGLALNAIENAEFLGKKEReITLGVQKGH-QSLFTPTTINRIETALA 487
148361067 431 ----------------------DWNDIIPQLKLSGLALNAIENAEFLGKKEReITLGVQKGH-QSLFTPTAINRIETALA 487
296108398 431 ----------------------DWNDIIPQLKLSGLALNAIENAEFLGKKEReITLGVQKGH-QSLFTPTAINRIETALA 487
52842953  431 ----------------------DWNEIIPQLKLSGLALNAIENAEFLGKKEReITFGVHKGH-QSLFTPTTINRIETALA 487
182681665 412 -------DGKITDVG-------QWLALVERIELSGPSKQLAAHAAFVSHENNvLSLALAPEF-EYLQSTRSVADLTQGLT 476
198283699 436 ----------------------DWRRVLASLAVSPMIAEYLRYGQALRCDPEaVELAVEPNYlPFLLKTEARRALHQALT 493
218666373 436 ----------------------DWRRVLASLAVSPMIAEYLRYGQALRCDPEaVELAVEPNYlPFLLKTEARRALHQALT 493

145299061 798 PELGQAVQVEVTLg-TVPDQETPLEIEHRLYLGVREQVSRDLEQDPNVQFLRQRFGAVLHQESIEPL 863
53804576  478 KLLGRPIKLTIRC--ESLDAETPAAADQRAQIERQREAELEIENDATVHALKDMFGAQIVAGSTRPL 542
54295584  488 GYYKSPVKIILNS--QDAVHASPAQQKEKATQERQEQAEAALHADPVFQQLKQEFSAELVKNSIVLL 552
54298738  488 GYYKSPVKITLNS--QDAVHASPAQQKEKATQEKQEQAEAALHADPVFQQLKQEFSAELVKNSIVLL 552
148361067 488 GYYKSPVKIILNS--QDAVHASPAQQKEKATQEKQEQAEAALHADPVFQQLKQEFSAELVKNSIVLL 552
296108398 488 GYYKSPVKIILNS--QDAVHASPAQQKEKATQEKQEQAEAALHADPVFQQLKQEFSAELVKNSIVLL 552
52842953  488 GYYKSPVKIILNT--QDAVHASPAQQKEKASQEKLEQAEAALHADPVFQQLQQEFSAELVKNSIVLL 552
182681665 477 RLLGQAPEVKIEA--RNIQVETLHERTYRQKSERQQLAEEAFMSDHVVQHLIYQQAAKVVTDSIRPY 541
198283699 494 AYYGREPRLSIVAltIETGVGSLVQEDRAQLASRQAAAEARVAADPRIGAFLEALDARVESIEIVAA 560
218666373 494 AYYGREPRLSIVAltIETGVGSLVQEDRAQLASRQAAAEARVAADPRIGAFLEALDARVESIEIVAA 560
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