Conserved Protein Domain Family
DUF116

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pfam01976: DUF116 
Protein of unknown function DUF116
This archaebacterial protein has no known function. The protein contains seven conserved cysteines containing a CxxCxxC motif and may also be an integral membrane protein.
Statistics
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PSSM-Id: 426541
Aligned: 94 rows
Threshold Bit Score: 126.066
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_011989237     223 IFCGR--REVEYHLNMVGAEILNRVFRDTFLK--TEDKIIFLPACMClkPYnTCRRKKTDKGFICMRCSEnCKVNILNRI 298 Clostridium...
jgi:Mvol_1552     60 LKFFLwiGTEYSFY-NVAIDFYNKYYYKKFLE--SKRKVLILPHCLR--DL-ECPAKLGKDGIKCIHCKK-CPLGDLIKA 132
Q2NET2            58 KNIMKffKCDELFVDRVSINLRNRLNINSFKKlnAKDLIVILPHCLR--AK-NCPAKLGSSGLSCIKCGK-CSVGIFEEI 133 Methanospha...
agres:mru_1096    60 KSLANflRLDDALVDHIGIEVRNKVNKPKFDQipPEEKIIVLPHCLR--SR-DCEASLKESGIKCTFCGK-CAIGTIKSK 135
CDG64531          59 KKFSEsmGVNAKIVDNIGVEVRNKVNEKHFKKinPSDTILVLPHCLR--HR-ECEATLETSGLVCKDCKR-CVIGVLKDK 134
O26659            60 KKFSEtlGLNSRIVDQIGVEVRNKINEKRFKSidPHDKALVLPHCLR--NP-ECEARLERTGLICTGCNR-CIIGKIKER 135 Methanother...
NZAGRC:Abm4_0890  59 KSLSNwlGFEDTMVDQMSVSLRNHVNKTNFNNtdNSRKILVLPHCLR--SS-DCQARLDETGLVCDKCGK-CSIGVIKEK 134
jgi:Plim_2915     77 REMLAthGEPEKFLGFAMVMLGNVFWREQFLAipFERRMLLLPHCLK--HAeGCPADYDEFGLDCERCGA-CSIADYKVK 153
Q7UR26            81 RRMLEeaDLPESYLGWVMVMISSEFWADALASvpPERRLFLLPHCLK--HAeGCPAEYDQFGMNCKECGA-CSIADFRSI 157 Pirellula sp.
jgi:Psta_0175    118 RRVLAeaGQGEGFVGWMMVVLATEFWRDQVASipPSRRLFLLPHCLK--HAeGCPADYDEFGLECKKCGA-CSIADFRGL 194
WP_011989237     299 GKKYNF-KVYIVPHESNAF--SGRKHIRygdiGIVGIACVLNLIEGGLKARNLNLVPQCVILDYCGCknhwhksgIETDI 375 Clostridium...
jgi:Mvol_1552    133 GEECGYmATFIVPGSTFMKrlLRECKPD----GIFAVACHVDLFMGMNGVSKLGIPVQGVLLLKDGC--------VCTIV 200
Q2NET2           134 CERKGI-GIYIVPGSTFIKrvIKQRPFK----GVICVACPVDLNQALMFLSN--YITQGVYLLNDGC--------INTRV 198 Methanospha...
agres:mru_1096   136 AEPMGY-KVFIVPGSSFVKkiIEQNKFK----SVVGVACHVDLNQTMMALSD--FYPQGVLLSTSGC--------FETRV 200
CDG64531         135 GEEMGL-RVFIIPGSTFLKkiVEQNKFK----AVIGVACFQDLNLAMMNLSK--FPCQGVPLLRDGC--------VNTKV 199
O26659           136 AEAIGY-TVFVIPGSTFIKkiVEEHRFK----AVLGVACYQDLNLAMMKLSR--FSPQGVPLLRDGC--------FKTKV 200 Methanother...
NZAGRC:Abm4_0890 135 AESIGY-KVFIVPGSSFVKkiIENNDFD----SVVGVACYEDLNLTMMKLNQ--FSPQGVLLSKTGC--------FETKV 199
jgi:Plim_2915    154 AEQLGY-KVLVAEGSPIVLkiIVSGHID----GILGVACLNVLEKAIDKVLIAGVPSYAVPLHSGDC--------KNTTL 220
Q7UR26           158 AEDMGY-RVLVAEGSPVVMkiIVGGYVD----AVVGVACLNVLEKAIDKVLLAGIPCMAVPLLSSDC--------RNTKV 224 Pirellula sp.
jgi:Psta_0175    195 ADEMGY-KVLVAEGSPIVLkiIVSGYVD----AIVGVACLNVLEKAIDKILLAGIPCMAVPLLSSDC--------RNTSV 261
WP_011989237     376 NYRKLFEIL 384 Clostridium kluyveri
jgi:Mvol_1552    201 DKEEVIRRl 209
Q2NET2           199 NENEVIYLL 207 Methanosphaera stadtmanae DSM 3091
agres:mru_1096   201 DVSKVLSTI 209
CDG64531         200 DARAVLEKM 208
O26659           201 DFRAVLEKM 209 Methanothermobacter thermautotrophicus str. Delta H
NZAGRC:Abm4_0890 200 DVRSVLEKI 208
jgi:Plim_2915    221 DESWVWECl 229
Q7UR26           225 DEPWVEQMI 233 Pirellula sp.
jgi:Psta_0175    262 DDDWVMEMI 270
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