6AHR


Conserved Protein Domain Family
Ribonuc_P_40

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pfam08584: Ribonuc_P_40 
Ribonuclease P 40kDa (Rpp40) subunit
The tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule and at least eight protein subunits. Subunits hpop1, Rpp21, Rpp29, Rpp30, Rpp38, and Rpp40 (this entry) are involved in extensive, but weak, protein-protein interactions in the holoenzyme complex.
Statistics
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PSSM-Id: 462526
Aligned: 48 rows
Threshold Bit Score: 190.605
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6AHR_L               75 HELITPEFISTFIKKGSCYALTYNTHIDEDNTVALLPnGKLILSLDKDTYEET--GLQGHPSQFSgrK--IMKF-IVSID 149 human
XP_015785426        100 HLLIHPVLIEYYVKKGYLYALSIDTQVHLDDCVALSS-KTLTLSLTESTYRRL--NLTGTKSLLVrnKkiMQKY-IVNIK 175
Q17J50               78 QTLANRAFIEGFIKQGKFYAVSFRTRLDTDDCVAVVPpGTLVLHLNKETFQSL--GLEGQVSEFArkR--NSKY-VVRID 152 yellow f...
EGI64413             75 SDLLNIEFIEAFVKKGEINLLTLENKIDLENSICVTPtGYLILSLLTDDYQAL--GLEGKPSVFShkS--HTRY-IVRID 149
XP_019884111         74 cDLLSTEFIEAFVKKGEVSLMTIENKIDLQNSICVTPtGYLLLSLLTEDYQAL--GLEGKASSFNckP--HTRY-VVTIN 148
XP_004359396        139 HQLINYQFVTNCIVKGEFIGLSQLSGLDSGNVVAFLAnGTVVLNVNKETYEVL--GLTGKHSAFNk----GQRF-IITIN 211
Q54W23              134 DLLLSHEFIDKYIKNGGFYAISQLNFIDSGNVVAFLPnSKIILNVDKETYQEL--GLLGKSSVFKn----LQRY-IITLD 206 Dictyost...
Q6C7H2               65 predgSSFSASVFQKSDAWIIS-KSRIDSDNVFAVWR-GNVHMSLTRSTYQTS--GLNGKKSRYGd------KY-LISFN 133 Yarrowia...
WGS:AATM:SJAG_00955  70 sCLLSSSLYESFVQNGTITLLS-DSLPDSSSSIALYN-GTIWISMDKDTYLCA--GLSAKASGNQp---kNTRW-DALFN 141
XP_311176            80 IELLKNEFVEAFVKRGTLYAVSTNINLESGGCLVITPqGELEMSLSRETYQMVkgNLDGSv------IskRGDMvVIKLD 153 Anophele...
6AHR_L              150 LM-ELSLNLDSKK----YERISWSFKEKKp-LKFDFLLAWHK---TGS---EES-T--MMSY------------------ 196 human
XP_015785426        176 LSyAQNLEAEKRN----YQRTFRYLRNCN--LKFDLLMKWEPnpqATK---NLSpSslLKFFehlkctpgmrggyllcei 246
Q17J50              153 LH---TLQPESKF----FKRVRDCLGRDCl-GRFDLQVAWTPpepPAGvrsRVCpSsiAKYFadl-------------as 211 yellow f...
EGI64413            150 LT-NENFIPGKKN----YERIRIALEERLt-QKFDVIVSWDPpd------iSMCpSsiAAWF------------------ 199
XP_019884111        149 LK-SENFVPGKKN----YERTRIALEQRLk-QSFDVIVSWDPpn------tNLCpSsiAAWF------------------ 198
XP_004359396        212 LM-EKKY-STEDG----YKRLNWCFNQRIgdINLLCRMSTNAferLKSlphKVLaNdiDFSF------------------ 267
Q54W23              207 MT-SKEYQRGSKS----YTRLIWSLKDRLssINLICFYQKLNstqLQSidfpqgvk------------------------ 257 Dictyost...
Q6C7H2              134 LR-NPNFHIGTKQ----HNRFLFGLEQLDk-LHPDLEYSVTVhanDARyvsEYLsNvkEVPLk----------------- 190 Yarrowia...
WGS:AATM:SJAG_00955 142 IS-DTPFKYGSKN----FERLRKGLERL---PDFNFI--------------ATCpSdkIQDFleaapftv---------- 189
XP_311176           154 LK-SPKCREQLGHvnlaFD------------ITLRWIPPKSTttkENN---VPDpQvhGSSIaeylrvvcrlqvenvpdg 217 Anophele...
6AHR_L              197 FSK-YQIQEHQPKVALSTLRDLQCPV--------L----------------QSSEL-EGTpEVSCRA------LELFDWL 244 human
XP_015785426        247 EVNqIHLHLCQPSIKIFDRSNIQAPKdlvqfqepMadesaikddthldevnEMSTKsKKQsPEDCPV------LDTIDWI 320
Q17J50              212 TDQnLKVELMPTMIKTHQEYGLNVPV-------------------------FNISEdDDNgKEYCSA------GELIEYM 260 yellow f...
EGI64413            200 YARnYNVCLCCQKFSQKIKYSLTIPT--------Yedtc------------------------------nntdIDFFEWL 241
XP_019884111        199 YARnYEVCLCHQTFSQRTKYSMALPT--------Lqeg--------------------------------cnlDKFFEWL 238
XP_004359396        268 -------------------DSIHLPLd-----------------------iKDVTQiIDKqEQQELV------MALNEVI 299
Q54W23              258 -------vlpsynqPTQEILNLRLPT--------Lniine--------------nlniNNsNNDIKMiyndfiNEWVEVL 308 Dictyost...
Q6C7H2              191 --------------TTVSERNVLVPS--------MtppvvpeltdahsgakVDVSQkYRDhLFESWA------LGLQEWV 242 Yarrowia...
WGS:AATM:SJAG_00955 190 -------rcepirlEHNTLRSQKIPPv-----------------------lFEPNFpYKNnDDDDLStlkenaFDILEYM 239
XP_311176           218 YKKiTRTKECIPLI------DTSNPFk-----------------------dGEQAYiRQ--------------DQLLEYI 254 Anophele...
6AHR_L              245 GA--------VFS----NVDLNNe-----PNNFISTY---C-CPEPSTVVA--------KAYLCTIT------GFILPEK 289 human
XP_015785426        321 GS--------IFT----GVEMTQs----lVDPEITSF---Y-LPESDTSLLk-------QLLCIQMS------GFFTPND 367
Q17J50              261 GM--------LAL----SCNTEE-------EEYLNSY---DfCGERVei---------gNAKVMHWN------GFFTPEQ 303 yellow f...
EGI64413            242 GV--------FSI----DGDLSTk----rEDNYANTY---Q-CPSPSIHVK--------QVQYLQWT------GFFTRQK 287
XP_019884111        239 GI--------FSI----GGDLSNg----eTDNYVNTY---E-CPPLSIDIG--------QVQHLQWT------GFFTRQK 284
XP_004359396        300 GTcicgvvtpFNVdfvlAGQKKKskdngsSESQFDSY---SfISSPEIDNNnnnnnnnnSVSHSSQTfisfkkGMILPSE 376
Q54W23              309 GF--------ASL----GINLNQvkdfeiGNSLLSQ------CPIAT------------KCLKATQK------GLVSNSF 352 Dictyost...
Q6C7H2              243 GL--------ASI----GAGRIAsd--dnVNNLFSQYqveDgQPA--------------NVTNIQVV------GM----- 283 Yarrowia...
WGS:AATM:SJAG_00955 240 SL--------LGL----HSPLLQst--naTDPYVSTY---T-IPMKNagep-----qtgDITQITVS------GLLTPDI 290
XP_311176           255 GV--------LALdcn-----------saPIEYVSSY---R-LDECKKKTD--------TVTILHRQ------GVITPEE 297 Anophele...
6AHR_L              290 ICLLLEHLCHYFDEPKLA--PWVTLSVQGFADSPVSWEK--NEHGFRKGGEHL-YNFVI 343 human
XP_015785426        368 VRNLLLELAKLVKTNDPDevPFVSLIVHGFDHCCVSWDEkcNEHGAKINGENH-YGIVL 425
Q17J50              304 VEAVHNAMRRALDVQDYV--PWMGMYVQGFSDSPIGFRM--RENYFHTDGENC-YAIVM 357 yellow fever mosquito
EGI64413            288 IQEVYNVLKQYILSRDSL--PWISLDIQGFADSAISFDL--KEHTFLTDGDNS-YTIVF 341
XP_019884111        285 MHEMYNALKEYVLSRKTL--PWVSLDVQGFADSPTSWDL--KEHMFFTDGDNS-YTIIf 338
XP_004359396        377 IVPLAKECRQLVATGSA---PWAAVHVSGFADSPISWGL--NEHAYGLSGEND-YTLVF 429
Q54W23              353 ILELIEKIKLMLSKGLI---EYGVLNIYGFADTPISWNS--IEHNFLYGGEND-QSLLI 405 Dictyostelium discoideum AX4
Q6C7H2              284 -CPLLASKLKILGEQTNA--PFFAFTVYGVQDTPYSWDN--KEHQYDNGGEND-YTIID 336 Yarrowia lipolytica
WGS:AATM:SJAG_00955 291 CLCLYSRIQSP---------EWFFTGLVGYPCTPVSWIG--KVHVHNYSGENAiYTLsr 338
XP_311176           298 ADGSIMRLVELVGECDTI--PWVGMHFQGFSHTPVDLIYr-GDQGVSLNQDSA-YTMVI 352 Anopheles gambiae str. PEST
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