Conserved Protein Domain Family
GATase1_PfpI_2
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cd03139: GATase1_PfpI_2 
Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus
Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus. PfpI is an ATP-independent intracellular proteases which may hydrolyze small peptides to provide a nutritional source. Only Cys of the catalytic triad typical of GATase1 domains is conserved in this group. This Cys residue is found in the sharp turn between a beta strand and an alpha helix termed the nucleophile elbow.
Links
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Statistics
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PSSM-Id: 153233
Aligned: 72 rows
Threshold Bit Score: 145.763
Created: 20-Oct-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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conserved cys
Feature 1:conserved cys residue [active site]
Evidence:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                     
AAU17677    7 VGIFLfneveVLDFAGPFEVFSITkvhe------------------ekpFTVYTVSqngemitarnglk----------- 57  Bacillus cereus E33L
EAL91195    3 FAMLLfpgfeALDVFGPLEVLNVLser--------------------kqIYLSLLAssltpvstqspdpaarragsicaq 62  Aspergillus fumiga...
XP_681796  72 YGVVLfpafeMLDVFGPLEVLSWAarl-------------------hekLDLYLLAetldpvttqpqsaamntfn----- 127 Aspergillus nidula...
EAA71720    7 YAVALfpgfqALDVFGPLDVLNFTskr--------------------qhMEVSLLHasldpvstfveggpaci------- 59  Gibberella zeae PH-1
XP_363969  30 IGIILfpgfqPLDVIAPADVMMALtsfhppq------------lsgsvnMTISFIWkeagpvwarspprlnpappnpnip 97  Magnaporthe grisea...
CAD01112   68 YALLLfptfeILDAYGPIEILQFVghfhpirllifslqapyssglapvlTTPSLASspinnplnssfyptfnpth----- 142 Neurospora crassa
EAA73956   58 VGVVLfqgfdMIDVFGPLDPLQLMslg-------------------vqkLNLHLIAetldpvttkpvamnkfds------ 112 Gibberella zeae PH-1
XP_664364   6 VGALVfn-yqAVDVIGPIDLLNSAgkalltsltqyt-tlspktiakapeFVFHHIGetldpvaltagvt----------- 72  Aspergillus nidula...
XP_368159  31 YGLVMfpaveLQDGIGPIDPLQILaak--------------------hnMTLYILAetmqpvssqipigvtpf------- 83  Magnaporthe grisea...
XP_364948  12 MGVLLeg--vQISDIMGIDLIGNLsrkyvsaaqgln-pgiarflesaidLEIFYLAetlaptevtpsfky---------- 78  Magnaporthe grisea...

Feature 1                                                                               #     
AAU17677   58 ------------vqpdysiedlppvDILIIPGGkaawe-nevknDIIINWVRQQMke----------vkLMTSVCTGAFL 114 Bacillus cereus E33L
EAL91195   63 evlptgtfadylqdarapdgvkgniDVLVVPGGagtry--phaiDPVIEFVRGIApp----------vkYIMSVCNGAGV 130 Aspergillus fumiga...
XP_681796 128 ------ssffptvnpthtfddnpelDVLIVPGGlgtr---npnmDRTLQFISSTYpr----------vqYLITVCTGSAL 188 Aspergillus nidula...
EAA71720   60 --------gqsvvpthtyetapddiEVLLVPGGfgard--penvMRVRQFVKERYpk----------lkYLLTVCTGSAI 119 Gibberella zeae PH-1
XP_363969  98 --agvfpiqapsfvathsfadapplDVVLVPGGagsrvlhdhndTSVEDFVKERYpt----------lrYLLSVCTGSGF 165 Magnaporthe grisea...
CAD01112  143 ------pipttdqqweemrevlesvDVLMVPGGegvyspdlegkGRELDFLRRMVgefgiggtkggkdkYLVTVCIGAAV 216 Neurospora crassa
EAA73956  113 -------sffptvpptntfddeldlDLLIVPGGsgar---npnlQAVTSYIAKMFpk----------vkILMTICTGAGV 172 Gibberella zeae PH-1
XP_664364  73 ------------lvptttindapelDILLIGGDspir---snipESYKEFIRRHVag----------gkLLFTNCTGAAV 127 Aspergillus nidula...
XP_368159  84 --------apsilpthtfadapddiQVLIVPGGpgvrd--lqtsASAEAYIRATHpk----------leHLITICTGSIL 143 Magnaporthe grisea...
XP_364948  79 ------------lpnvtyddcprdlDLVLIGGNgfe-----sqsEASKKFIREAWpk----------trVWMTTCVGTLW 131 Magnaporthe grisea...

Feature 1                                                                                     
AAU17677  115 LAKAGLLEGLKATTHWAs----------iQTFKKDfsnvevmenvkFVDEg---------hIITSAGISAGINMSFHIVK 175 Bacillus cereus E33L
EAL91195  131 LARAGVLDGRRATTNKMl----------wGQTTALrgevrwvrdarWVADg---------nVWTSSGVSAGIDMMLAFVR 191 Aspergillus fumiga...
XP_681796 189 VAQTGILDGRRATTNKAs----------wDSVIVNgpnttwvpearWVVDg---------nIWTSSGISAGIDATLAFVA 249 Aspergillus nidula...
EAA71720  120 VAQTGILDGREATSNKRs----------fDWVLTQganvkwarnarWVVDg---------nIWTSSGISAGIDMTYAFIA 180 Gibberella zeae PH-1
XP_363969 166 LAKSGLLDGRRATTNKAa----------wSWPTQFgtnvtwvptarWVEDg---------nIWSSSGVSAGIDMTYAFFS 226 Magnaporthe grisea...
CAD01112  217 AARAGVLDGRRATTNKMvwgevtalgekvKWVSPAr----------WVVDg---------nIWTSSGVTAGLDLTFEFVR 277 Neurospora crassa
EAA73956  173 AARSGVLDGHMATTNKNa----------wATMKEMgpkvnwvsparYVIDg---------kIWSSSGVTSGLDLIFEFIA 233 Gibberella zeae PH-1
XP_664364 128 VAQTGVLDGKAATVNKIe----------fNWIKQRypavkwtkaknWIVDg---------nIWTGSGAVAGMDMVAHWIK 188 Aspergillus nidula...
XP_368159 144 AGRAGALDGKLATTNKSa----------wKSLTPSvpgvkwvaparWIRDg---------nVWSSSGVLSGIDLIHAWIK 204 Magnaporthe grisea...
XP_364948 132 LASAVDLTGLKVTTNRVa----------iEFGKQLypgae-wqdkrWVVEdkvyegqgkgeLWTGGAAGAGLDMVTEWCF 200 Magnaporthe grisea...

Feature 1                         
AAU17677  176 NLl--GVEIAEETAKSMEYD 193 Bacillus cereus E33L
EAL91195  192 ETy--GEDLASGIAQEIEYV 209 Aspergillus fumigatus Af293
XP_681796 250 ELy--GKENATVISEYMEYE 267 Aspergillus nidulans FGSC A4
EAA71720  181 EQy--GQDIADDTAKGSEYV 198 Gibberella zeae PH-1
XP_363969 227 RIl--DQKLVDRTMNNIEYA 244 Magnaporthe grisea 70-15
CAD01112  278 QMypdGVDMANLIAGAIEHE 297 Neurospora crassa
EAA73956  234 TFw--GKEQSERLAGIAEHV 251 Gibberella zeae PH-1
XP_664364 189 ENy--GLDVLTEAARGLDFE 206 Aspergillus nidulans FGSC A4
XP_368159 205 VMf--GDEEEQRIAGLTEYI 222 Magnaporthe grisea 70-15
XP_364948 201 QNf--DKDFVNALSTYPLEF 218 Magnaporthe grisea 70-15

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