1KNX


Conserved Protein Domain Family
hpr-ser
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TIGR00679: hpr-ser 
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Hpr(Ser) kinase/phosphatase
Members of this family are the bifunctional enzyme, HPr kinase/phosphatase. All members of the seed alignment (n=57) have a gene tightly clustered with a gene for the phospocarrier protein HPr, its target. [Regulatory functions, Protein interactions, Signal transduction, PTS]
Links
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Statistics
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PSSM-Id: 273214
Aligned: 57 rows
Threshold Bit Score: 339.45
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1KNX_A         4 LLVKELIEQFQdcVNLID-G--HTNTSNVIRVPGLKRVVFEMLGLFSS---Q---IGSVAI-LGKREFGFLSQKTLVEQQ 73  Mycoplasma pneu...
ZP_06342195    7 VTIQEIINFFH--FTQVT-Gd-EKALQNFTKDNDINRPGFELMGNFRDs--V---PSRLVL-IGNKETRYINNMPEDIQE 76  Bulleidia extru...
ZP_04565734    6 ITVGELLNNEH--YVQVT-Gd-EKSLERPIYVAEINRPGFELAGFFKHs--D---FRRIII-FGDKESAFINEMSEERQR 75  Coprobacillus s...
ZP_08730351    6 INVRKLIEKFN--LTLDNhK--ENIELRDIYSPSVKKLGLELAGEFVGd--N---YQHNVIcWGNSENSYFEKIGESKAK 76  Mycoplasma colu...
WP_011077127   4 kdVHKNFSNYK--LE-------SVGREKEIISNRVTRTGLEFADFFVHk--D---LKAVVL-WGNDEYLYLKQFDEKLVK 68  Mycoplasma pene...
WP_015726023   2 IKVLSIYKRFN--GKYLN-Rt-PDNEQREILFPGFNRLGMELNGCFLNe--Q---NRSVVC-WGKQESNFLDLFEESKQI 71  Mycoplasma haem...
WP_006688665   7 LFVSQVVRKFN--LNVVA-N--SDYIDREISTTGITRVGFELAGEILFk--E---IWNIVY-FGSKESNYFNKFSETIIS 75  Ureaplasma parvum
WP_010925512   5 LFVSELIKHFD--LEVLN-HdfPEIEDREILTPSIKRLGLELSGHFIYd--A---ISGVIVgWGTNESKFFEKIGSEKAK 76  Mycoplasma pulm...
WP_011182959   4 LTIKELVNKFD--FEIIS-G--AEHIDSEITVYGLNRAGLELTGYFNEk--EdkkHKRAIL-MSSKENNYMSQFSDEEAY 75  Mesoplasma florum
WP_013609461   5 VLVSSIFKRFG--GSFVN-Kn-SVSSQRVIFEPALSRLGMELNGAFAFankE---IKTVVV-WGKMECEFLSSLQEERKL 76  Mycoplasma suis

1KNX_A        74 QILHNLLKLNPPAIILTKSF--TDPTVLLQVNQTYQ---VPILKTDF-FSTELSFTVETYINEQFATVAQIHGVLLEVFG 147 Mycoplasma pneu...
ZP_06342195   77 KRFRQLLEYYSAAIIVTHDN--PVPKIMKRLAQELN---FPILSTPL-ETQQVTAELISFLDEQLAEEDTKHGVLVSVDG 150 Bulleidia extru...
ZP_04565734   76 EIFPFLINDEVPCIIVAKGN--ECPAILIEIARKKD---FPIFITES-ATGRVSIELTNILDEALAPETLIHGVFLNIYG 149 Coprobacillus s...
ZP_08730351   77 KVLDLVLQVQPPLLILSCGIkeMAKNWIVEIADKYN---IPVFWSKQ-DTAKIMTTIGTYLNDMFSEEIQVHGCLVSIGG 152 Mycoplasma colu...
WP_011077127  69 EKIEKIFQLTPPLVVLSRSF--PAKGIILELAKKYD---ISILSTKE-SSADLTNYINTFLTEKLSKKEYLHGNLIELFG 142 Mycoplasma pene...
WP_015726023  72 EILSKILETDPPLFLLSNNF--RHAELLNKLNKDFNgnrSSLICMGY-STLEIFTLIGTWIAKTFAKWTTVHGVVLNVYG 148 Mycoplasma haem...
WP_006688665  76 KKLGKILDLNPPLIIFGKNF--KHAGILLKLAERYK---IPIVEVKY-SFYELNFTINSYISQKLSHQSLVHGTLLSVFG 149 Ureaplasma parvum
WP_010925512  77 SSIEEIFSRKIPMLVLSKGFdkNYYSTIIEIANKHK---TPVIFYKA-SLSEINTILGIYLLQYFAKKVQVHGTLVSVFG 152 Mycoplasma pulm...
WP_011182959  76 EKYKNLIKMGSPVIIVTQKF--T-DERLSKIAKEFN---FPLLKINYpSTSELTQKILDIYDLYFAPTIEVHSTLMNIYG 149 Mesoplasma florum
WP_013609461  77 ETLKSILLKNPPLFLLSSNF--SEVELIKKANEKWNenrSAIIKLDY-STKDIFTSVGTWLSKSLATWSTIHGSVVSVFG 153 Mycoplasma suis

1KNX_A       148 VGVLLTGRSGIGKSECALDLINKNHLFVGDDAIEIYRL-GNRLFGRAQEVAKKFMEIRGLGIINVERFYGLQITKQRTEI 226 Mycoplasma pneu...
ZP_06342195  151 VGVLIMGASGMGKSETALELIHHGHILIADDRVDICHI-HNDLYGRAPEILKGLLEIRGIGIIDVEKMFGVSAIRHRSKI 229 Bulleidia extru...
ZP_04565734  150 KGVIIKGDSGIGKSEIALELVKRGHLLVADDAVELYHL-GQSIVGKAPEVLTNLLEIRGIGVIDVSKMFGISSILDKDKV 228 Coprobacillus s...
ZP_08730351  153 TGVLIVGNSGVGKSEATLELIQKGHLFISDDAVLIKHI-GVHFYGTAPQITKNFIEVRGIGLIDIKYTYGIKSITDGAVI 231 Mycoplasma colu...
WP_011077127 143 LGVLLMGKSGLGKSETSIELIKHGHMFIADDAIVCSNV-FNKIIGRAPKRFFGFLEVRGLGIINASRVFGIEKVKESTQI 221 Mycoplasma pene...
WP_015726023 149 EGVLITGEAGVGKSEAAAELLKMNHLFLGDDAIDIARI-GNTIVAKANPFSEGFMHIRGLGILNMREMYGGMKMIDETKI 227 Mycoplasma haem...
WP_006688665 150 IGVILMGESGVGKSELAIELVKKGHIFVGDDAILVNRIgGN-LYGRAEDSTKDFIEIRGLGIMNFSRSFGIERMIESTKI 228 Ureaplasma parvum
WP_010925512 153 MGILIVGDSGLGKSEAALELVQKGHVLISDDAVLVSHy-GNKYFGKAPYITKNLIEVRGLGLIDILSVHGLKSVLPECEI 231 Mycoplasma pulm...
WP_011182959 150 KGVLIFGQSGIGKSEVSLELMKKNHLFVGDDRIVISNR-NSELFGKSHALLQNLIEVRGIGIIDISKVQGQQLIMPETKI 228 Mesoplasma florum
WP_013609461 154 EGVLLTGEPGIGKTEVILDLLSLNHLFLGDDAIRVTRL-GNAVIARANPNSSEFIQIRGIGLINIKEAIGRSKIIDESKI 232 Mycoplasma suis

1KNX_A       227 QLMVNL---LSLEKQ--TtvT-FERLGTE-LK-KQRLLGVDLSFYEIPISPGRKTSEIIESAVIDFKLKHSGYNSALDFI 298 Mycoplasma pneu...
ZP_06342195  230 DLVIDL---VPFDSQ--A--E-YDRIGGE-DLeHMEILGVSVPKLTLPISAGRSLSVLVETAVRHYMLVKTGNAGAKIIE 300 Bulleidia extru...
ZP_04565734  229 DLIIQL---DRWVPS--R--E-YTRVGVEeNDsTEEILGVKIPKIVVPVSSGRSMSVIIEAAVMNMRLREYGVDSSKEFV 300 Coprobacillus s...
ZP_08730351  232 DFVAEL---VYPSEN--V--H-FDRLGID-YL-QYNILDGYLPKIQIPVKNGFSAASLIEAAVSTFVARKDGSSVLSQIE 301 Mycoplasma colu...
WP_011077127 222 NVIIEL---VEFDPK--V--HtFERLGKD-LQ-YKEILGVKIPYYLIPITPGKKTSDMIEVIVAQLKLMLSGYNSFKEME 292 Mycoplasma pene...
WP_015726023 228 TMVVNL---KDQKDE--NrlH-FENVGEE-IN-YRPLLEVPLPYYVIPVTSGRKISEIIELAVIDMKLKRKGYSAAQEMN 299 Mycoplasma haem...
WP_006688665 229 EIVIEL---IKPAKH--EkiK-FERFGRE-IQ-HKEFLETKIAHYYIPVIEGRSISDIIETAITDYKLKTSGYNSAEEFI 300 Ureaplasma parvum
WP_010925512 232 NFVVEL---KDYEQN--Ks-N-FDRLGNK-VL-KYQIGEWKIPKIEIPIRQGRSVASLIEASANMFLSKLNGHDVLAMIQ 302 Mycoplasma pulm...
WP_011182959 229 HMGIEL---FKFQEGgiD--N-TDRLGNE-WT-QKDFLGLKIPYLRVPVSAGRNLANIIEAAVGQLKVNES--SDAQDII 298 Mesoplasma florum
WP_013609461 233 NVIIELkshKKFSET--M--P-LENWGEE-IK-YKELLNVKIPHYVLPVQAGRNISELIQACVNDHKLKKSGYNSAAAFD 305 Mycoplasma suis

1KNX_A       299 ENQKAIL 305 Mycoplasma pneumoniae
ZP_06342195  301 KRFMVLA 307 Bulleidia extructa W1219
ZP_04565734  301 DRILKNI 307 Coprobacillus sp. D7
ZP_08730351  302 KRKDDIN 308 Mycoplasma columbinum SF7
WP_011077127 293 EKSMEdd 299 Mycoplasma penetrans
WP_015726023 300 RKYKKLI 306 Mycoplasma haemofelis
WP_006688665 301 LQINKKg 307 Ureaplasma parvum
WP_010925512 303 ERSLNde 309 Mycoplasma pulmonis
WP_011182959 299 ELLAKRN 305 Mesoplasma florum
WP_013609461 306 KITKAHL 312 Mycoplasma suis
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