Conserved Protein Domain Family
GltA

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COG0372: GltA 
Citrate synthase [Energy production and conversion]
Citrate synthase is part of the Pathway/BioSystem: TCA cycle
Statistics
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PSSM-Id: 440141
Aligned: 748 rows
Threshold Bit Score: 137.919
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_045090092   7 TqilsdsiaftsnidknlftKMGVKR---GLrnedhSGVLAGLTRIGDVvgyerqeDGSLkpipGKLYYRGLDVEELVAg 83 
WP_011177690   1 Ms---------------------ISL---GL-----EDVFIKYTSLTSI-------DGEK----GELRYRGYDIKDLVE- 39 
WP_011921426   1 M--------------------SQISR---GL-----ENVFIKTTSLTYI-------DGEN----GILRYGGYDIEDLVE- 40 
ACR43298       1 M--------------------SVVSK---GL-----ENVIIKVTNLTFI-------DGEK----GILRYRGYNIEDLVN- 40 
WP_010916495   1 Mpe----------------tTEEISK---GL-----EDVNIKWTRLTTI-------DGNK----GILRYGGYSVEDIIN- 44 
WP_069178805  12 qlrreridclkrehgdfvisnvtVEQiysGI-----RGVPIQVSDISYV-------DPEK----G-VRYQGYTVDECINl 74 
WP_059060500   1 Msevlf--------------evtkDNletGL-----RGYPVGYCTTSSV-------DPVK----G-LFYVGHPVSELDS- 48 
WP_009886204   1 M--------------------EEISP---GL-----ENVYIKYTELTFI-------DGQK----GIMRYRGYDINELAE- 40 
WP_013775111   1 M--------------------SEVSK---GL-----ENVFIKTTSLTYI-------DGEA----GILRYGGYDINDLVE- 40 
WP_126450156   1 Mse---------------teKAEVSR---GL-----ENVYIKATSLTYI-------DGER----GILRYRGYDINDLAN- 45 
WP_045090092  84 iqkenR------LGFEETIFLLLSGRLPLKEELEATKSLIAETMPLNHMA-TMNILALQGKNIMNILARSVLELYCYD-- 154
WP_011177690  40 -----H------CSFEEVAYLMFYGELPKRDELEHFKSNVMKNYKIPENVkNIIKNMPRDGDALAIMEAAFAALSTEE-- 106
WP_011921426  41 -----H------TSFEEVVHLMLYGDLPTKLQLQRLKSALDEAYEVPQQViDMIYSLPRDSDAVGMMETAFSALSSIY-- 107
ACR43298      41 -----Y------GTYEETIYLMLYGKLPTKKELNDLREKLNEEYEVPQEVlDSIYLMPRDADAIGLLEVGTAALASID-- 107
WP_010916495  45 -----Ng-----AQAEEIQYLFLYGELPNAQELKIFKENVQKGYNIPDFViNSIRQLPRESDAVAMQMAAVASMAASE-- 112
WP_069178805  75 l---pNpedsrfPYIGGLYYLLMTGELSTVARAVEIEEDWRARSEVPDVVfNVIDAFPDGAAAMAMFSAALLSMSSGSkf 151
WP_059060500  49 ------------WEPEQVIYLLNHGRVGTADEVAKFTEELRGRSKCVPELiKSIQQLPKNGHPMKLFSAALLLAGTFE-- 114
WP_009886204  41 -----K------SSFEKVSYLMLFGKFPDDSELKNFQNKINSHLALDDYLkDILRAMPETSDSLGILQTLLSAKASKE-- 107
WP_013775111  41 -----N------CEYEEIIHLMLFGDLPSASQLQKIKEKINESYNVPYQVfEVLEKLPQDADAVGMLETAFSMLSSFY-- 107
WP_126450156  46 -----N------ATYEEVVHLMLYGELPNSEQLKRVKDVLNSSYEVPEDVlRVMEVLPKDSEPVALMEAGLAALATHE-- 112
WP_045090092 155 ----ENPDDI-SP-NNLIHQSINLIAKFPTIIAYAYQVLrhdvrgRS-LHVRLPHPEKSVAENFLFMMKGPnKYT-ELDI 226
WP_011177690 107 -------YTW-EK-ERDREKAAEIMGRALGIVSAVFRYR------DG-REIKDPE-NKGYAEAFLNACFDS-GID-EDKI 167
WP_011921426 108 ----G--MPW-NK-ATNRDNAVKLVARASTVVANVLRAK------EG-KKPAIPEPSESFAKSFLKASFSR-TPT-EEEV 170
ACR43298     108 ----KN-FKW--K-ENDKEKAISIIAKMATLVSNVYRRK------EG-NKPRIPEPSDSFAKSFLLASLAR-EPT-AEEI 170
WP_010916495 113 ----IK-FKW-NK-DTDRDVAAQMIGSMSAITANVYRHI------LG-MPAERPKPSDSYAESFLKAAFGR-NVT-KEEV 176
WP_069178805 152 aaqyADGMDKkEhwIPMLDDSMDLIARAPEICAYIYNKKy-----RN-HEHIKPDPGLDYAANFAHMVGLD-D---PQVY 221
WP_059060500 115 ------GK------NDYREDCLNLIAQVPEIAATVINHH------AGwGATNPSKPELGYMENFTQMLKVP-NGNkEELT 175
WP_009886204 108 ----SN-YKY-TK-ENDGEKIPEILGSVLSMVANIYRLK------SG-NNIIDPEPGESYAETFLKACSG--SAD-KNKI 170
WP_013775111 108 ----N--YPW-KK-DENKWRAIEIIAKTSTLVSNIYRIK------EG-MKPRLPELSDSYARTFLETAFSR-RPS-DEEV 170
WP_126450156 113 ----KE-FKW--K-ERDREKALEIIGKVSTITANVYRVK------QG-LTPRVPSPGESYAKSFLEATFSK-SFT-SQES 175
WP_045090092 227 KILDLALILHAEHgGGNNSTFSVRVTSSTETDTYSAIAAGIGSLKGPLHGGANVKVMGMLEDMKknisdweDANQVDEYL 306
WP_011177690 168 KAMNAALILYIDH-EVPASTTAALVASSTLSDMYSCVTAAIAALKGPLHGGAAEAAYKQFLAIK-------SPENVDSWF 239
WP_011921426 171 KAMDAALILYADH-EVPASTTAALVTSSTLSDIYSCVVAALAALKGPLHGGAAEEAFKQFVEIG-------EPDMTESWF 242
ACR43298     171 NAMDKALILYTDH-EVPASTTAALVAASTLSDMYSSLTAALAALKGPLHGGAAEEAFKQFVEIG-------DPNRVEMWF 242
WP_010916495 177 DAINTALILYTDH-EVPASTTAGLVAVSTLSDIYSGITAALAALKGPLHGGAAEAAIAQFDEIK-------EPSNVEKWF 248
WP_069178805 222 DLLRMTLLLLADHeNANVSAHTAHLVGSALSDIYLACSAGLNGLAGPLHGLANQECFKYIQEVCdrfqgvpDEDSLTAYL 301
WP_059060500 176 RAFKLFNILHYDHgGGNLSAFVGKAVASGLEDLYGSISAAMCALAGPRHGKANQDCLTFVHGLVqelgegaDEAQVEQAI 255
WP_009886204 171 SAMDSALILYMDH-EIPASTTAALVTASTLSDMYSSLASAIAALRGPLHGGAAEGAYRQFLEIG-------EPENVNAWF 242
WP_013775111 171 KAMNATLIIYADH-EVPASTTAALVTASTLSDMYSCMVSALAALKGPLHGGAAEATFEQLKEIG-------DESKVEEWF 242
WP_126450156 176 SMMDKFLVLYADH-EVPASTTAALVTASTLSDMYSCMVSAITALKGPLHGGAMEAAFRQFKEIG-------DPSKVDDWF 247
WP_045090092 307 RKILrkeafDKTGLIYGLGHAVYTISDPRTGLLKEMARDLAkek-grEKEFALMELIENRIVEvfrESKKsnAKANVCVN 385
WP_011177690 240 NENIl----NNKKRLMGFGHRVYKTYDPRMLIFKELARKNAktd-eqKKILELAERLEALGVK-----NF--GQKKIFPN 307
WP_011921426 243 KRKIi----EGKSRLMGFGHRVYKTYDPRAKIFKKYAKVISernsdaRKYFEIAQKLEELGVE-----TF--GAKHIYPN 311
ACR43298     243 NDKIi----NQKNRLMGFGHRVYKTYDPRAKIFKELASTLIernseaRKYFEIAQKLEELGIK-----QF--SSKEIYPN 311
WP_010916495 249 NDNIi----NGKKRLMGFGHRVYKTYDPRAKIFKGIAENLSknnaevKKIYDIATKLEDLGVK-----QF--GSKGIYPN 317
WP_069178805 302 QQTL-----SSGRVIPGYGHAVLRSIDPRFAVEYKFGKATAa----dDPYFQTAKAIFKTAPAi-lKATG--KVKNPWPN 369
WP_059060500 256 RDRL-----EKKELVFGFGHAVLRVEDPRATLLYQVADQYYp----nHPLVKMARLLRSAGTKv-lKENP--KISDPYPN 323
WP_009886204 243 ENNIl----NGKRRLVGFGHRVYRTYDPRLKTFKKYADILStte-eqKKILAIAKRLEEAGVK-----AF--GSKGIYTN 310
WP_013775111 243 DKKIi----KEKNRLMGFGHRVYKTYDPRAKIFKKYAEEIAktp-eaKKYLRIATKLEELGIK-----HF--AEKRIYPN 310
WP_126450156 248 ERTIv----KGGNRLMGFGHRVYRTYDPRGKIFKSMAEVAAqg--eaRKYLEIAEKLETLGVK-----HF--ESKKIYPN 314
WP_045090092 386 VDFYSGFVYDAIGLP--T-EVFTPLFAMARIVGWSAHRIEEMNfsSK---R---LIRPAYKNVRE-LQGFIPIN 449
WP_011177690 308 TDYYSGIVFNEIGFP--L-YMFTTLFALSRVVGWVAHISEYVEs-EE---R---LIRPRAIYIGPeKRDVVPID 371
WP_011921426 312 TDFYSGVVFYALGFP--V-YMFTSLFALSRTLGWTAHVIEYVEd-QH---R---LIRPRALYVGPlKRDVVPIE 375
ACR43298     312 TDFYSGIVFYALGFP--V-YMFTALFALSRTLGWLAHIIEYVEe-QH---R---LIRPRALYVGPeHQEYVPID 375
WP_010916495 318 TDYFSGIVYMSVGFPlrN-NIYTALFALSRVTGWEAHFIEYVEe-QQ---R---LIRPRAVYVGPaERKFVKLP 383
WP_069178805 370 VDALTGVLFNHFGLT--HsSFYTVLFGLSRLMGFTCHIVWARAv-NK---P---IERPKALTTRIl-EAM--VS 431
WP_059060500 324 VDAISGILLTAAGFPy-P-DYYTVLFGLARVVGIGRQIVYERE--EAregKgtpIIRPKYFFKAK--EEL--AG 389
WP_009886204 311 TDFYAGMVFNAIGFP--V-DMFTTLFGLSRISGILAHITEYVEt-QE---R---LIRPRAIYRGSgERKY-Pe- 372
WP_013775111 311 VDFYSGIVFYSLGFP--E-YMYTTLFALSRVLGWLAHIIEYVEe-QH---R---LIRPRALYVGPiKRDFVPLK 374
WP_126450156 315 TDFYAGILMYGLGFP--D-FMFTPLFALSRTLGWLAHVVEYVDe-QH---R---LIRPRALYVGPgKREFVPLN 378
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