1N0E


Conserved Protein Domain Family
TIGR00242
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TIGR00242: TIGR00242 
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division/cell wall cluster transcriptional repressor MraZ
Members of this family contain two tandem copies of a domain described by pfam02381. This protein often is found with other genes of the dcw (division cell wall) gene cluster, including mraW, ftsI, murE, murF, ftsW, murG, etc. Recent work shows MraW in E. coli binds an upstream region with three tandem GTGGG repeats separated by 5bp spacers. We find similar sites in other species. [Cellular processes, Cell division, Regulatory functions, DNA interactions]
Links
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Statistics
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PSSM-Id: 129345
Aligned: 6 rows
Threshold Bit Score: 230.062
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1N0E_A        26 MLLGTFNITLDAKNRISLPAKLRAFFEG-S----IVINRGFENCLEVRKPQDFQKYFEQFNSFPSTQKDTRTLKRLIFAN 100 Mycoplasma pneu...
P45056         1 MFRGATAVNLDSKGRVAIPTRYRAEILEkNqgqmVCTVDIRQSCLLLYPLDEWEKIEQKLLALSNFDPTQRRLQRVMLGH 80  Haemophilus inf...
P55343         1 MFMGEYQHTIDAKGRMIVPAKFREGLGEq-----FVLTRGLDQCLFGYPMHEWKQIEEKLKALPLTKKDARAFTRFFFSG 75  Bacillus subtil...
P75467         1 MLLGTFNITLDAKNRISLPAKLRAFFEG-S----IVINRGFENCLEVRKPQDFQKYFEQFNSFPSTQKDTRTLKRLIFAN 75  Mycoplasma pneu...
WP_014894001  14 MLLGTFNLTLDNKNRISLPAKLRSFFDS-S----IVINRGFENCLEIRKPADFESYFQTFNNFPNTQKDTRTLKRLIFAN 88  Mycoplasma geni...
P22186         1 MFRGATLVNLDSKGRLSVPTRYREQLLEnAagqmVCTIDIYHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGH 80  Escherichia col...

1N0E_A       101 ANFVDVDTAGRVLIPNNLINDAKLDKEIVLIGQFDHLEIWDKKLYEDYLANSESLET-----VAERMKDVK 166 Mycoplasma pneumoniae
P45056        81 ATECEMDAQGRILLSGPLRQHAKLEKGLMLVGQLNKFEIWSDVEWHTQIAEDIEIGSst-dfAADALNDFS 150 Haemophilus influenzae R...
P55343        76 ATECELDKQGRVNIASSLLNYAKLEKECVVIGVSNRIELWSKVIWEQYTEEQEDSFAe----IAENMIGFD 142 Bacillus subtilis subsp....
P75467        76 ANFVDVDTAGRVLIPNNLINDAKLDKEIVLIGQFDHLEIWDKKLYEDYLANSESLET-----VAERMKDVK 141 Mycoplasma pneumoniae M129
WP_014894001  89 ANLVELDSANRILIPNNLISDAKLDKEIVLIGQFDHLEVWDKVQYEQYLASSESLET-----VAERMKDAK 154 Mycoplasma genitalium
P22186        81 ASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQlatgdLSERLQDLS 151 Escherichia coli K-12
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