1R52


Conserved Protein Domain Family
aroC

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TIGR00033: aroC 
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chorismate synthase
Homotetramer (noted in E.coli) suggests reason for good conservation. [Amino acid biosynthesis, Aromatic amino acid family]
Statistics
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PSSM-Id: 272865
Aligned: 10 rows
Threshold Bit Score: 464.917
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1R52_A         8 FRVTTYGESHCKSVGCIVDGVPPGMSLTEADIQPQLTRRRPGQSKLSTPRDEKDRVEIQSGTEFGKTLGTPIAMMIKNED 87  baker's yeast
Q9HJY7         8 MKMTVFGSSHGEAVGSIIDGFPIGFKIPLDYVQKYMEYRRPGSSILTSQRKEDDEVEIISGLHEGYTDGSPLTLIIRNKN 87  Thermoplasma ac...
Q9Z6M2         9 FSFTTWGESHGPSIGVVIDGCPAGLELHESDFVPAMKRRRPGN-PGTSSRKENDIVQILSGVYKGKTTGTPLSLQILNTD 87  Chlamydia pneum...
Q9JT81        10 FTVTTFGESHGAGLGCIIDGCPPGLELSEADIQFDLDRRKPGTSRHVTQRREADQVEILSGVFEGKTTGTPIALLIRNTD 89  Neisseria menin...
Q58575        12 FRVTVFGESHGKAVGAVVDGCPANLPLSEEDIQKELDRRRPGQSIFSTPRKEEDKVEILSGIFEGKTTGAPICSIVYNKN 91  Methanocaldococ...
P28777         8 FRVTTYGESHCKSVGCIVDGVPPGMSLTEADIQPQLTRRRPGQSKLSTPRDEKDRVEIQSGTEFGKTLGTPIAMMIKNED 87  Saccharomyces c...
Q9WYI2         1 MKLTIAGDSHGKYMVAILEGLPSGIRVDEELIRRDLFRRRNCYGRGKRMKMEEDAFEIVSGLWKGITTGAPVTILIPNR- 79  Thermotoga mari...
Q9KXQ4         4 LRWLTAGESHGPALVATLEGLPAGVPITTEMVADHLARRRLGYGRGARMKFERDEVTFLGGVRHGLTMGSPVAVMVGNTE 83  Streptomyces co...
WP_005873408   8 FRLTTFGESHGKAIGGVIDGCPAGLFVDMETIERELLRRRPGQSHYTSPRQESDMVQFISGLFRGETTGAPIAFMIDNKD 87  Porphyromonas g...
WP_001269860   1 MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYGRGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKD 80  Streptococcus p...
1R52_A        88 -------QRPHDYSD----------MDKFPRPSHADFTYSEKYGIKA-SSGGGRASARETIGRVASGAIAEKFLAQnSNV 149 baker's yeast
Q9HJY7        88 -------VISSYYSE----------IRENPRPGHSDYTMFLKYGEFRnYEGGGFLSGRMTAPLVAAGSIAKAYLEG-MGI 149 Thermoplasma ac...
Q9Z6M2        88 -------VDSSPYEN----------SERLYRPGHSQYTYEKKFGIVD-PNGGGRSSARETACRVAAGVVAEKFLAN-QNI 148 Chlamydia pneum...
Q9JT81        90 -------QRSKDYGN----------IATSFRPGHADYTYWHKYGTRD-YRGGGRSSARETAARVAAGAVAKKWLKEkFGT 151 Neisseria menin...
Q58575        92 -------MRPKDYSK----------IKDTPRPGHADLTYRLKYKNYD-YRGGGRASGRVTIGHVIGGAIAKKLLSYtYNI 153 Methanocaldococ...
P28777        88 -------QRPHDYSD----------MDKFPRPSHADFTYSEKYGIKA-SSGGGRASARETIGRVASGAIAEKFLAQnSNV 149 Saccharomyces c...
Q9WYI2        80 --------AGNPVKD----------VRSVPRPGHIDYAAWVKYKLPDlNIYVERSSARWTVALTAAGSLLKSLLKEfG-I 140 Thermotoga mari...
Q9KXQ4        84 wpkweqvMAADPVDPevlaglarnaPLTRPRPGHADLAGMQKYGFDEaRPILERASARETAARVALGAVARSYLKEtAGV 163 Streptomyces co...
WP_005873408  88 -------VRSADYDS----------LSSIFRPGHADYTYFHKYGIRD-TRGGGRSSARETAVRVVAGAVAKQLLAPl-GI 148 Porphyromonas g...
WP_001269860  81 hqkwldiMSAEDIEDrlk----skrKITHPRPGHADLVGGIKYRFDDlRNSLERSSARETTMRVAVGAVAKRLLAElD-M 155 Streptococcus p...
1R52_A       150 EIVAFVTQIGE-IKM--NrdsfdpefqhllntitREKVDs------mGPIRCPDASVAGLMVKEIEKYRGNKDSIGGVVT 220 baker's yeast
Q9HJY7       150 KVKSYMRSIGD-VEC--Srv-------------sGEAYS--------FETRMPDPECDARARELIMRVMKAGDSIGGRID 205 Thermoplasma ac...
Q9Z6M2       149 FTLAYLSSLGS-LTL--Phyl----------kisPELIHk------iHTSPFYSPLPNEKIQEILTSLHDDSDSLGGVIS 209 Chlamydia pneum...
Q9JT81       152 EITAYVTQVGE-KEI--Rfeg-------------ceHISq-------NPFFAANHSQIAELENYMDSVRKSLDSVGAKLH 208 Neisseria menin...
Q58575       154 KIIGYTIKIGK-IEG--Dfsyykn----pevfenEKSLErlieiiesNPLRCPS-MNEKEMEEYVLKAMENKDSVGGVVE 225 Methanocaldococ...
P28777       150 EIVAFVTQIGE-IKM--NrdsfdpefqhllntitREKVDs------mGPIRCPDASVAGLMVKEIEKYRGNKDSIGGVVT 220 Saccharomyces c...
Q9WYI2       141 EVLGFVTRLGN-VEA--Rdipgd-------feelKRRRDe-------SVVFCPDPEATKEMVAEIDRAKEEGNTLGGKVK 203 Thermotoga mari...
Q9KXQ4       164 EIVSHVVELASaKAP--Hgvyp--------tpadVERLDa-------DPVRCLDADASKAMVAEIDQAHKDGDTLGGVVE 226 Streptomyces co...
WP_005873408 149 RCTAYTSQIGP-VCI--Pqena--------keysPEEVEs-------SPIRCPDPNASGLMEAVIETAKKESDSVGGIVD 210 Porphyromonas g...
WP_001269860 156 EIANHVVVFGG-KEIdvPenlt--------vaeiKQRAAq-------SEVSIVNQEREQEIKDYIDQIKRDGDTIGGVVE 219 Streptococcus p...
1R52_A       221 CVVRNLPTGLG--EPCFDKLEAMLAHAMLSIPASKGFEIGSGFQGVSVPGSKHNDPFY-FekE--TNRLRTKTNNSGGVQ 295 baker's yeast
Q9HJY7       206 TVVENFPGGVG--EPFFDSVESSIAHAIFSIPAVKAIEFGDGFRLASMLGSEANDPFD-L--A--DGKIVTKTNHNGGIL 278 Thermoplasma ac...
Q9Z6M2       210 FITSPIHDFLG--EPLFGKVHALLASALMSIPAAKGFEIGKGFASAQMRGSQYTDPFV-M--E--GENITLKSNNCGGTL 282 Chlamydia pneum...
Q9JT81       209 IEAANVPVGLG--EPVFDRLDAEIAYAMMGINAVKGVEIGAGFDSVTQRGSEHGDe---------LTPQGFLSNHSGGIL 277 Neisseria menin...
Q58575       226 IVALNVPVGVG--NPIFNKLNGELARALMSINAVKGVEIGAGFKAAEMYGSEMNDEMY-F--Dd-DKNIRFKTNNCGGIL 299 Methanocaldococ...
P28777       221 CVVRNLPTGLG--EPCFDKLEAMLAHAMLSIPASKGFEIGSGFQGVSVPGSKHNDPFY-F--EkeTNRLRTKTNNSGGVQ 295 Saccharomyces c...
Q9WYI2       204 VIARGVPAGIGsySDLFKKLDSKIGSLFFAIPAVKGVVIGS---EEMWYGFDYLDEFE-L--E--DGKIKRKTNNLGGIE 275 Thermotoga mari...
Q9KXQ4       227 VLAYGVPVGLGshVHWDRKLDARLAGALMGIQAIKGVEIGDGFELARVPGSRAHDEIV-G--T--PDGIRRVSGRSGGTE 301 Streptomyces co...
WP_005873408 211 CQISDVPVGWG--EPLYGKLHAALGAAMLSINAAKGFEVGDGFALASMRGSEANDQMVaA--E--DGGISFLSNHSGGIS 284 Porphyromonas g...
WP_001269860 220 TVVGGVPVGLGsyVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEIL-W--Sk-EDGYTRRTNNLGGFE 295 Streptococcus p...
1R52_A       296 GGISNGENIYFSVPFKSVATISQEQKTATYDGEEGILAA--KGRHDPAVTPRAIPIVEAMTALVLADALLIQKARD 369 baker's yeast
Q9HJY7       279 GGITNGMPIRFSIAVKPTPSIHIPQQTVNLSTSEKTTITv-KGRHDPCVAIRAVPVVECLTSFVLLDLLIQSGNVN 353 Thermoplasma acidop...
Q9Z6M2       283 GGITIGVPIEGRIAFKPTSSIKRPCATVTKTKKETTYRTpqTGRHDPCVAIRAVPVVEAMINLVLADLVLYQRCSK 358 Chlamydia pneumoniae
Q9JT81       278 GGISTGQDIHVNIAIKPTSSIATPRRSIDINGNPIELAT--HGRHDPCVGLRAAPIAEAMLALVLIDHALRHRAQN 351 Neisseria meningiti...
Q58575       300 GGISCGTPIVLRIAVKPTPSIGKKQKTINLKTLENVEIEi-EGRHDPVIVPRIVPVAEAMVAITLADLMIKGGFIH 374 Methanocaldococcus ...
P28777       296 GGISNGENIYFSVPFKSVATISQEQKTATYDGEEGILAA--KGRHDPAVTPRAIPIVEAMTALVLADALLIQKARD 369 Saccharomyces cerev...
Q9WYI2       276 GGITNGEDVWVNVSVKPIPTTGKPLKSVDLRTMEPAKTP--YVRSDVTAVPPASVVCEAALAVVISDALLEHLGDG 349 Thermotoga maritima...
Q9KXQ4       302 GGLTTGELLRVRAAMKPIATVPRALKTVDVATGEAAQAH--HQRSDVSAVPAAGIVAEAMVALVLADAVAEKFGGD 375 Streptomyces coelic...
WP_005873408 285 GGISTGQDIRFRVAFKPTPTIGQKQQTVNEQGESISLSA--VGRHDPCVVPRAVPVVEAMTWLTLADAYLASRSGR 358 Porphyromonas gingi...
WP_001269860 296 GGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT--VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSD 369 Streptococcus pneum...
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