1OQY


Conserved Protein Domain Family
rad23

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TIGR00601: rad23 
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UV excision repair protein Rad23
All proteins in this family for which functions are known are components of a multiprotein complex used for targeting nucleotide excision repair to specific parts of the genome. In humans, Rad23 complexes with the XPC protein. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Statistics
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PSSM-Id: 273167
Aligned: 6 rows
Threshold Bit Score: 470.917
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1OQY_A     8 VTITLKTLQQQTFKI-RMEPDETVKVLKEKIEAEKGrdaFPVAGQKLIYAGKILSDDVPIRDYRIDEKNFVVVMVTKTKA 86  human
P54726     3 VTITLKTLQQQTFKI-RMEPDETVKVLKEKIEAEKGrdaFPVAGQKLIYAGKILSDDVPIKEYHIDEKNFVVVMVTKAKA 81  house mouse
P54728     1 MQVTLKTLQQQTFKI-DIDPEETVKALKEKIESEKGkdaFPVAGQKLIYAGKILSDDTALKEYKIDEKNFVVVMVTKPKA 79  house mouse
CAA21170   1 MNLTFKNLQQQKFVIsDVSADTKISELKEKIQTQQN---YEVERQKLIYSGRILADDKTVGEYNIKEQDFIVCMVSRPKT 77  fission yeast
CAA72742   1 MKLTVKTLKGSHFEI-RAQPNDTVMAIKKNIEDLQGkdnYPCGQQLLIHNGKVLKDESTLAESKISEDGFLVVMLGKSKT 79  carrot
P32628     2 VSLTFKNFKKEKVPL-DLEPSNTILETKTKLAQSIS---CEESQIKLIYSGKVLQDSKTVSECGLKDGDQVVFMVSQKKS 77  Saccharomyces cerev...
1OQY_A    87 GQ------------------------GTSAPPEASPTAAPESS--TSFPPAPTSGMSHPPPAAREDKSPSEESAPTTSPE 140 human
P54726    82 GQ------------------------GIPAPPEASPTAVPEPS--TPFPPVLASGMSHPPPTSREDKSPSEESTTTTSPE 135 house mouse
P54728    80 VTtavpattqpsstpsptavssspavAAAQAPAPTPALPPTSTpaSTAPASTTASSEPAPAGATQPEKPAEKPAQTPVLT 159 house mouse
CAA21170  78 ST-------------------------------STPKSAASPAp--NPPASVPEKKVEAPSSTVAESTSTTQTVAAAAPS 124 fission yeast
CAA72742  80 MS-------------------------STGTPAAQSSSAPAPTp--APAVAPAPAPAAAPASAVIPNTTVPEAPLSPAFA 132 carrot
P32628    78 TK------------------------TKVTEPPIAPESATTPGreNSTEASPSTDASAAPAATAPEGSQPQEEQTATTER 133 Saccharomyces cerev...
1OQY_A   141 SVSGSVPssgssgr---eedaasTLVTGSEYETMLTEIMSMG---YERERVVAALRASYNNPHRAVEYLLTGIPGSPE-- 212 human
P54726   136 SISGSVPssgssgr---eedaasTLVTGSEYETMLTEIMSMG---YERERVVAALRASYNNPHRAVEYLLTGIPGSPE-- 207 house mouse
P54728   160 SPAPADStpgdssrsnlfedatsALVTGQSYENMVTEIMSMG---YEREQVIAALRASFNNPDRAVEYLLMGIPGDREsq 236 house mouse
CAA21170 125 NPDTTATseap--------idanTLAVGAQRNVAVENMVEMG---YERSEVERAMRAAFNNPDRAVEYLLTGIPEDILnr 193 fission yeast
CAA72742 133 PSDTYGEaa-------------sNVVAGSNLEQTIQHIMDMGggmWDTNMVSRALRAAYNNPERAVDYLYSGIPEMAEaa 199 carrot
P32628   134 TESASTP----------------GFVVGTERNETIERIMEMG---YQREEVERALRAAFNNPDRAVEYLLMGIPENLRqp 194 Saccharomyces cerev...
1OQY_A   213 ------------------------PEHGSVQESQV-----------SEQPATEAAg--ENPLEFLRDQPQFQNMRQVIQQ 255 human
P54726   208 ------------------------PEHGSVQESQA-----------PEQPATEAAg--ENPLEFLRDQPQFQNMRQVIQQ 250 house mouse
P54728   237 avvdpp----------pqavstgtPQSPAVAAAAA-----------TTTATTTTTs-gGHPLEFLRNQPQFQQMRQIIQQ 294 house mouse
CAA21170 194 qreesaaalaaqqqqsealaptstGQPANLFEQAAls--------eNENQEQPSNtvgDDPLGFLRSIPQFQQLRQIVQQ 265 fission yeast
CAA72742 200 vpvshfqg-------dqinagnnaISDNGVAGAAPgapnslplnmfPQETLSGVTgagLGSLEFLRNNPQFQTLRSMVQR 272 carrot
P32628   195 epqqqtaaaa--eqpstaattaeqPAEDDLFAQAAqggnassgalgTTGGATDAAq-gGPPGSIGLTVEDLLSLRQVVSG 271 Saccharomyces cerev...
1OQY_A   256 NPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGE-----LADISDVEGE--------VGAIGEEAp-QMN---- 317 human
P54726   251 NPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGE-----LADISDVEGE--------VGAIGEEAp-QMN---- 312 house mouse
P54728   295 NPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPVQE-----AGSQGGGGGGggggggggGGGIAEAGsgHMN---- 365 house mouse
CAA21170 266 NPQMLETILQQIGQGDPALAQAITQNPEAFLQLLAEGAEG--------ESALPSG---------------G---I----- 314 fission yeast
CAA72742 273 NPQILQPMLLELGKQNPQLLRQIQEHHEEFLQLINEPVEA-------SEGDMFDQ------------PEQDvpQ------ 327 carrot
P32628   272 NPEALAPLLENISARYPQLREHIMANPEVFVSMLLEAVGDnmqdvMEGADDMVEGedi---evTGEAAAAGlgQGEgegs 348 Saccharomyces cerev...
1OQY_A   318 -YIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFD 366 human
P54726   313 -YIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFD 361 house mouse
P54728   366 -YIQVTPQEKEAIERLKALGFPEGLVIQAYFACEKNENLAANFLLQQNFD 414 house mouse
CAA21170 315 -QIQITQEESESIDRLCQLGFDRNIVIQAYLACDKNEELAANYLFEHGHE 363 fission yeast
CAA72742 328 -EITVTAADQEAIERLEAMGFDRGLVIEAFLACDRNEELAVNYLLENAGD 376 carrot
P32628   349 fQVDYTPEDDQAISRLCELGFERDLVIQVYFACDKNEEAAANILFSDHAD 398 Saccharomyces cerevisiae S288c
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