1R7C


Conserved Protein Domain Family
HCV_NS5a
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pfam01506: HCV_NS5a 
Hepatitis C virus non-structural 5a protein membrane anchor
The molecular function of the non-structural 5a protein is uncertain. The NS5a protein is phosphorylated when expressed in mammalian cells. It is thought to interact with the ds RNA dependent (interferon inducible) kinase PKR. The N-terminal region of the NS5a protein has been used in the construction of the alignment for this family. The C-terminal region has not been included because it is too heterogeneous.
Links
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Statistics
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PSSM-Id: 366682
Aligned: 20 rows
Threshold Bit Score: 23.7006
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1R7C_A      2 GSWLRDIWDWICEVLSDFKTWLK 24  
Q69422   1866 IAWGLEIWQYVCNFFVICFNVLK 1888 GB virus-B
Q9WBT6   1964 VGYVWDLWEWVMRLLRRCVNRLR 1986 GB virus C variant troglodytes
O56073   1950 SELLWDFVDWLVRLGRMLSRRLS 1972 Pegivirus A
Q96898   1937 SQIVWDLLDWCIRLGRFLYNKLM 1959 Pegivirus A
O41892   1942 SEVLWDLLDWCVRLGRYLLRKIK 1964 Pegivirus A
O36194   1897 VGYVWDLWEWIMRQVRVVISRLR 1919 GB virus C
ABO37971    1 VGYVWDLWEWVMRQVRMVMAGLR 23  
P26661   1978 GSWLQDIWDWVCSILTDFKNWLS 2000 Hepatitis C virus isolate HC-J8
Q91TD8      2 GDWLRIIWDWVCSVLSDFKTWLS 24   Hepacivirus C
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