5JPW,1XDX


Conserved Protein Domain Family
DLC-like_DYNLT1_DYNLT3

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cd21455: DLC-like_DYNLT1_DYNLT3 
dynein light chain (DLC)-like domain found in the dynein light chain Tctex-type 1 (DYNLT1) family
The dynein light chain Tctex-type 1 (DYNLT1) family includes two isoforms, DYNLT1 and DYNLT3, which contribute to the differential regulation of dynein cargo binding. They are non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. The dynein complex contains either DYNLT1 or DYNLT3, but not both. The model corresponds to the dynein light chain (DLC)-like domain of DYNLT1 and DYNLT3.
Statistics
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PSSM-Id: 412003
Aligned: 142 rows
Threshold Bit Score: 71.4532
Created: 28-Jan-2020
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5JPW_A        17 DEVSNIVKEAIESAIggnayq-hskvnQWTTNVVEQTLSQLTKLgk--------pFKYIVTCVIMQkngaGLHTASSCFW 87  human
CBY31965      17 EKATEIIKEQITSVIgdqnys-rshaeQWSKSISENIAEELKKLnl-------ddIKFVINITLLEktdkCCSTASQCIW 88  Oikopleura dioica
XP_005766169  12 ETIKPLVERIVQKEIapdylw-nakssDLQSVVIENILKELAAEnenaaregkrpFKFVVLCELQQnvgaGLANACTCHW 90  Emiliania huxle...
XP_005826164  14 DEVYQVVKESVDAVLtnasyl-hakvpQWQSMIVESILKRLATLnk--------pFKFVVTSMISQntggATHTAHTCFW 84  Guillardia thet...
ETO29280      13 QTTEELLREEISGVLgdsqfd-ankvpQWCQRIVTNVLKKLVEAnksq----dfqYKYVVNTVVLErtgaGLHSTSSCLW 87  Reticulomyxa fi...
KFH63418      13 KAATQILEEVVKKVLkdatyr-tdlvpEWQAAIYKESLTRLTQMkg--------tFKYIVTSTIMEsvgaGVHISSTSLW 83  Mortierella ver...
KHJ44004      13 EELTAVAKEQIELVLgtqpys-henavLWNRVIVSNIIAQLMKFsk--------pYKFMVTCVLMQkggtGLHVASGSFW 83  pig whipworm
KRY12780      22 EEINIIVKQQLENVIgsqpyq-rnlvgQWNTTIAENVVHQLAQTnk--------hFKIMVNSILMEkhgsGLHVVSATYW 92  Trichinella pat...
XP_023214858  12 DEIKPVIKDAIETVIgnniyq-qnmidQWMSNIHKNILGQLIKLnk--------pLKYIVITVVVQrtgsGLHTTGSCYW 82  bark scorpion
TFJ84123      21 EDVTSITNEVIEGIIgayssydtsdagDWSDRIGANTVEALTAHfgrg---kerrYRFTVTVTLVQhg-eGISACSAAAW 96  Nannochloropsis...
5JPW_A        88 dsSTDGSCTVRWENktmYCIVSAFGL 113 human
CBY31965      89 dsDKDRQIKVRWENkglHVFADVFAL 114 Oikopleura dioica
XP_005766169  91 dsSTDGHCVFKYETehvQALVTVYGV 116 Emiliania huxleyi CCMP1516
XP_005826164  85 daETDGFAKYRFDNptlVCLTTVYGM 110 Guillardia theta CCMP2712
ETO29280      88 dkTSDSSSSVQWNNehmFCVTSVWAL 113 Reticulomyxa filosa
KFH63418      84 daESDGSAVFRFENktmVVFVYAFGL 109 Mortierella verticillata NRRL 6337
KHJ44004      84 dtATDVSVSVRWENkflNCVVEVFAV 109 pig whipworm
KRY12780      93 dvVADRSVSVRWESksvFCHVQIYFC 118 Trichinella patagoniensis
XP_023214858  83 deSTDGCCMVIWENdtiQCVSKVYVL 108 bark scorpion
TFJ84123      97 npETDFVVRVSWQNqaiTCLVVVFAL 122 Nannochloropsis salina CCMP1776
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