1DVP


Conserved Protein Domain Family
FYVE
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pfam01363: FYVE 
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FYVE zinc finger
The FYVE zinc finger is named after four proteins that it has been found in: Fab1, YOTB/ZK632.12, Vac1, and EEA1. The FYVE finger has been shown to bind two Zn++ ions. The FYVE finger has eight potential zinc coordinating cysteine positions. Many members of this family also include two histidines in a motif R+HHC+XCG, where + represents a charged residue and X any residue. We have included members which do not conserve these histidine residues but are clearly related.
Links
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Statistics
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PSSM-Id: 426221
Aligned: 129 rows
Threshold Bit Score: 46.6056
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1DVP_A        156 PNWA---DGRVCHRCRVEF-TFTNRKHHCRNCGQVFCGQCTAKQC-PL-PKYGIEKEVRVCDGCFAALQR 219  fruit fly
Q4E0Z5        317 VEWVddsTVSSCKGCDRLF-GFWRRRHHCRNCGKVFCNSCSSNTC-VI-PESSYTDPERVCDACFHEVEN 383  Trypanosoma cruzi
Q38F57        317 VEWEpnsLFSTCVVCRRAF-FLWRRRRHCHNCGKLVCSSCSANHI-TI-PGCSSASPERVCDSCFGKIRG 383  Trypanosoma brucei
Q4QF23        316 TPWVdeaSISACMACERPFgIL-RSKRFCHSCGRITCNACIGDLRiIP--ESRWKAPQRVCTACAGTLNG 382  Leishmania major
EEF28920      608 hKWVsgaDQSVCSGCRQAF-GFTRKRHNCYNCGLVHCHACSSKKAlKAaLAPTPGKPHRVCDACYAKLkt 676 
XP_001469235  313 KVWQpddDMENCMMCKEPI--GRWSRHHCRNCGRLVCANCSEKRA-II-EDLGYDTPVRVCYDCFRL-RS 377 
Q4DSM2         83 KLWQpddASQVCDVCGAMV--ARFTRHHCRRCGYLTCSKCLKFKT-IL-TEWSLTEKQRVCRRCAVPAVP 148  Trypanosoma cruzi
Q4DTA0        271 KVWQpddSSSECMICHAAI--GRFSRHHCRSCGRLVCDTCSMAKA-II-PALGFNAATKICDDCAQMGQR 336  Trypanosoma cruzi
Q7Q7F5        680 VEWKslrSVVNCPTCSIPFdQI-TKKNHCWKCGEVFCSRCIDKTLaLP--GHDSGNPVPVCRQCFRVVQQ 746  Anopheles gambiae str. ...
XP_001626810  612 IKWKsvrDVSQCSTCSLPIaFL-SRKYHCWNCGEVFCRRCIERQCsLP--AHYSENTVPVCKQCYKRIQH 678
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