Conserved Protein Domain Family
HflB

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COG0465: HflB 
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 440233
Aligned: 792 rows
Threshold Bit Score: 524.986
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_129893287  98 INgLLAy-------------------pLAQAr--nASatQpvArpSEKSVnTdYQAWnRYIGNGNptwSTTT----A-Ep 151
WP_085938655 112 alftsvvagwiafdyhshapstagkteLAREf--eSGp-H--Mw-LDRPL-D-ASVFaDKLRQGEi-aAVGV----DgQ- 177
WP_050742281  11 AA-LLLaa------------------lLFGr---pAA--A--M--EAQPV-A-YSEFiQDVQARRv-aYARI----TgQ- 54 
WP_012871440  13 LA-LAVf-------------------iLIGVg--iSM--R--A--TPQPV-N-LTQVlTDIRDGRv-tEIHL----AnDg 57 
WP_053013706  18 VAgLLVlaaavamdyhtqapasgprtaLALQf--eRDp-S--Pw-LANPR-D-VSEFeRALEQRQv-kEVGV----DgR- 83 
WP_011831660  26 aA-LLAsnavermse---aeslarkspAAAAf--eKAp-D--Dw-VKNPR-P-VSDFqLALEAGSl-aDVGIasggAgT- 91 
WP_011194261  15 MV-LFgl-------------------wLLQFfflpPL--T--T--RPTEL-S-YSAFlDALEDRRv-qEAVV----RdR- 60 
WP_104022665  49 IA-IAIaav-----------------vgWRVl--hPA--A--D--APPVI-A-YSELsRAIAAGQv-rDVLL----DeGd 95 
WP_099511418  28 ILgLLVaa------------------aVFMgpr----llA--E--PVAEI-S-YSDFtRELSDKKv-qKVLI----EsG- 73 
WP_011491062  25 IAgLLAfgvwhyqqra--pqvapaltgVANQmrhdAS--Aw----THEEK-D-ASQMlRDIHDGHv-aAVGV----SpS- 88 
WP_129893287 152 ---SL-------Dp--D-R--AIYTRAH-----VEgDa-G-LMPL--L----V-GH--H-----Vl---VNSIp----lG 188
WP_085938655 178 ---RVlat--trS---GeQ----FSTEL-----Va-Ge-EgLLAg--LetasR-EQ--GfaltrIs---VDARtv--geR 228
WP_050742281  55 ---RLeaa--yrD---G----TVRVVTLp----pG-Ea-R-LPLV--L----M-QY--G-----Ar---VEFVr----pA 94 
WP_012871440  58 qaaEVty----tD---E----SKTRVALp-----A-Ge-S-LTTL--L----T-DA--G-----Ip---VE-RwpdiypA 100
WP_053013706  84 ---RVlvt--trS---GeR----YSAEL-----La-Tq-QgLGAR--LealsQ-ER--GfaltpVk---VDQRsv--lqK 134
WP_011831660  92 ---MLlyt--lkD---GtK----LSALVpgctaVs-Ca-Gt-AADh-LaeksA-AK--GftlvaVd---VDWRgr--veR 147
WP_011194261  61 ---VLqgk--mvG---G----ESFTVTLp------pDaaG-LAER--L----E-EA--G-----Ve---QRYEv-----T 99 
WP_104022665  96 --nRVlaeltakQlvyG-RvtNVVTATIpp-rgV--Sv-E-TLDR--W----S-QS--G-----Ar---VRVAe----qD 146
WP_099511418  74 ---GLsvs--maD--------RDVFVRMpn-glV--Sa-D-YIER--I----T-AA--G-----Aq---VDFKk----pG 114
WP_011491062  89 ---AIlis--krD---GtKy---FVTDH--------Na-T-FSHAllLg---EpKSdeAaayqlVwlpdADIR------- 137
WP_129893287 189 ---Q-NS-A---W-VA---LL-WKVV-PAVIVIV-LL---LiFL-AaRN--NGarGGrsldNRISQLG-RSR-ARR-MEr 244
WP_085938655 229 ivaStGS------------VL-ERLF-TLLTVAA-MVvlgV-YL-L-RQgaMG--GG--------A-----K-ARL---- 270
WP_050742281  95 ---D-PI-A---F-RT---LL--RFI-PPLLILG-AI---L-WF-T-RRt-AG--GS----GGLLTME-QSP-ARL-YR- 141
WP_012871440 101 ---G-NG-A---I-SAdlmLL-LRIL-TIV-AVGvVI---F-VL-F-RRf--Gp-SSi----GTTPTR-RGS-FEP-IR- 151
WP_053013706 135 vgdStGA------------VL-QRLM-GLLTVAV-MGliaV-YL-V-RQt-QG--GG--------S-----K-AKL---- 175
WP_011831660 148 i----vA------------VF-QRISgPALWIAG-VAlvmL-LC-V-QIqaRG--DD--------D-----R-VRL---- 186
WP_011194261 100 ---R-TP-W---W-VT---LL-PTVL-WLAVMVG-LF---A-WA-Q-KRq-----------AGAFGLA-RST-VKP-LA- 143
WP_104022665 147 r-lH-SP-------EQ---II--QLL-SFAALLG-MI---G-FL-V-VRs-R---G-----------G-ATR-TRFaAT- 186
WP_099511418 115 ------------FdAAh--IA--GILgPIILVLA-VL---A-MLaI--Qt---------------DFKpTSRwPRV---- 152
WP_011491062 138 ---TaGSrWlqvFdQTr-dAIsV-LL-PLLLIGG-MV---W-FM---RRemR---G-----------G-----ARL-LD- 182
WP_129893287 245 vkesnplhpverktpsqlarpgqagssykprqSTEPPVTFADVAGIDEVRTEVEEIVQFLRSPERFDRLGAHIPRGALLV 324
WP_085938655 271 --------------------------------AEKPQTSFVDVVGASDAKTSLQQVTAFMRDPQKYLALGAKPPRGVLLE 318
WP_050742281 142 --------------------------------VGEASVTLQDVAGLDEVKAELQEVIDFLREPERYRAMGARIPRGILLS 189
WP_012871440 152 --------------------------------PGERVITFDDVAGAEEVKEEVADIVDYLRDPERFRRLGARIPRGVLLT 199
WP_053013706 176 --------------------------------AEKPQTNFDDVIGSAEAKAALQQVTAFMRSPEKYLALGAKPPRGVLLE 223
WP_011831660 187 --------------------------------AQRPRERFDDVVGAGSAKSALLRVGRFMEDPAAYLQVGARAPRGVLMT 234
WP_011194261 144 --------------------------------PGESPVTFADVAGMDEVKGELEEIVDYLKNPDKYRAIGARIPKGVLLY 191
WP_104022665 187 --------------------------------PPSRRLTLADVGGAREAQADLRDVIAYLKDPERFRNMGAKCPKGILLV 234
WP_099511418 153 --------------------------------VRSLPNRFDDVAGQDEAKAELQEVIAFLKDSEAFTRVGARIPRGLLMV 200
WP_011491062 183 ---------------------------------RAPALRFDDVIGASEAKAALADIRSYLSDPKQFTSMGVRAPCGILMV 229
WP_129893287 325 GSPGTGKTLLARAVAGEANVPFFSISASEFVEMFVGVGASRVRDLFNQARKAAPCVVFIDEIDAVGRKR-AMR--ATNND 401
WP_085938655 319 GPPGTGKTLLARALAGECKANFIAVDGSHFSSMFYGQGIAKVRELFATARKNAPCIIFIDEFDGIGKRAsGAKv-EGGQS 397
WP_050742281 190 GPPGTGKTLLARALAGEAGVPFFSASGSDFVELFAGTGAARVRALFDRARKAAPCIVFIDEIDALARRR-GVGa-GGGTE 267
WP_012871440 200 GPPGTGKTLLTRALAGEARASFFSVSGSEFVELYVGVGASRVRELFRKAKENAPAIIFIDEIDAIGRRR-GR---MEQSS 275
WP_053013706 224 GPPGTGKTLLARALAGECGANFIAVDGSHFSSMFYGAGITKVRELFATARKHAPCIVFIDEFDGIGKRStGNKv-AGGQS 302
WP_011831660 235 GPSGTGKTLLAKALAGETGARFIAVDGSYFTSMFFGLGVLKVRKLFRQARRSSPCILFVDEIDGIGRRSsGAGq-NASTT 313
WP_011194261 192 GPPGTGKTLLARAVAGEAGVPFFALSGSSFVELFVGMGASRVRELFAQARKNAPCIVFIDEIDAVGRQR-GSAavVGGHD 270
WP_104022665 235 GPPGTGKTLLARAVAGEAGVPVIQAAGSDFNEMYVGVGSKRVRQLAKQARDAAPCIVFIDEFDSLGGRR-GRPn-RSG-- 310
WP_099511418 201 GPPGTGKTLIAKALAGEAGVSFMAVSGSDFSAPLIGIAKGRVSKLFEQARKKAPCLIFIDEIDAIGRKR-GGGg-SAADR 278
WP_011491062 230 GGPGVGKTRLAQALAGECGANFISITGSYFSAKYYGVGIQKVKHLFELARKNAPTVIFIDEADGLAKRT-DTGs-GPVEA 307
WP_129893287 402 ERDQTLNQLLVELDGFDSRKAVVVMAATNRVDILDKALLRPGRFDRRITVSAPDRVGREAILKVHTRKT-PL-HEEISLE 479
WP_085938655 398 EENRIINKLLVEMDGFSTSDNIIVIGATNHVGNVDEALRRPGRFDLVARVNLPTVHDRRELFELCLARV-RAeSGQIDAE 476
WP_050742281 268 EREQTINQLLVEMDGFDSGEGVIVVAATNRPDVLDPAVLRPGRFDRHLTVDPPDRKGREQILAVHAREK-RL-SQAVALA 345
WP_012871440 276 EYDQTLNQILVEMDGFEERTTVVVVAATNRVDILDPALLRPGRFDRKVVVDLPDRKARRAILEVHARGK-PL-AENVNLD 353
WP_053013706 303 EENRIINKLLVEMDGFAESENIVVIGATNHVGNVDDALKRPGRFDLVARVALPNVNDRRELFQLCLKRV-KA-ADAIDLE 380
WP_011831660 314 EMNRIINCMLVEMDGFSDEERVIVVAATNHADNLDPALRRAGRFDMVIPVDLPTVAERAQLFDLYAGRV-AA-EPNLDTA 391
WP_011194261 271 EREQTLNQLLTEMDGFGAYEGVIVMAATNRPDVLDKALLRPGRFDRQIPVGPPDAAGREEILRVHAKGK-QL-DPSLDLA 348
WP_104022665 311 EEEVTLNQLLVEMDGMAGSEGVVWMAATNREDMLDPAVRRPGRFDRVVEVSLPTTNDRLEILKIHAKTS-KL-AADVDLE 388
WP_099511418 279 EFEATLNQLLVEMDGFNTTAGVIVIGATNRVDVLDPALLRPGRFDRQVHIGLPDISGREAILNVHARNV-KL-AEGVSMT 356
WP_011491062 308 ESNRIINQLLAEMDGFASNEGVIIVAATNHPDNLDEALRRPGRFDRTVQVRLPDREDRAKIFRFYAAKLkSK-SADIDYD 386
WP_129893287 480 RLARMTTGMTGADLANLVNEAALSAARRELEHVTYECFEEALARVQL-G--ALRPL--IMSEKERQIIAFHEGGHALVAY 554
WP_085938655 477 ALARASSGLSHADITNIVNRATVLAAESGSASVTQAHLHRALETHQL-Gg-EVSSLkaAFTETHRERIAVHEAGHALVAH 554
WP_050742281 346 EVARLTPGFTGADLANLLNEAALLAVRAGEREIGWPQVAMALERVTS-Gg-PPRRV--RAAAADRVRAAYHEAGHALAGL 421
WP_012871440 354 ELAARTTGMTGADLANVINEAAILAARDRRETITNQDLLEALDRTLA-Gp-ARNAR--RFSERERRVVAYHEAGHAVVAH 429
WP_053013706 381 TLARSSTGLSHADITNVVNRATVLAAEAGSSSVTQEHLHRALETHQL-Gg-EVSSIkaMFTPEARHRIAIHESGHAIVAH 458
WP_011831660 392 ALARMTSGMSPADIANAVNKAASCAAEAGSPVVTQEHLTQAVEAFQL-Gg-EVTGAprVLTEDTRKRLAYHEAGHALVAH 469
WP_011194261 349 AVARRTPGFTGADLANLLNEAAILAVRRGRSHITMSEIDEAIDRVVAgGp-ARKGR--MIRPEEKRRVAVHEAGHALVAT 425
WP_104022665 389 RLAALTVGHSGAELANLLNEAAIIAVHADSSEITNAHIEQARDKILL-Gr-VRSGV--TVSEDERRLVALHEAGHAIVGL 464
WP_099511418 357 SIAKGTPGFSGADLGNLLNEAAIFAAREGVGEVNREHLEAARNKILM-Gl-ERRSL--VISNEERRLVAVHEAGHALCAC 432
WP_011491062 387 QLARLTTGLSPATVAMVVNQAGLVARKSGDTEIASKHFMEAIKIARI-GdvSGAER--ALSEDERTRIAVHEAGHGLVAA 463
WP_129893287 555 HLPEADTVNRVTILPRGQSLGVTQFIAe-EDRYNYSRQSLMARIAVGLGGRVAEELTFgtDQVTTGAENDLQVVTDLARR 633
WP_085938655 555 AL-KAGRVERISIEPRGQALGVTFVSRe-DEVPLYGERELKARLSMLLAGREAELMNY--GNTTSGAADDLKRASELAIE 630
WP_050742281 422 ALRGSDRLVRVTILPHGRGLGHTLFRDqdEERYLHTRRDAFDRLTELLAGRAAEALVL--GEVSAGAADDLERATGLARE 499
WP_012871440 430 LLPHADPVRKVSIVSRGRAGGYTMIVPd-EDRGLWTRAQLSDRLAALLGGLAAEELIF--GDITTGSSNDLEQTTAIATS 506
WP_053013706 459 VM-KAGTVERVTIEPRGQALGVTFVTRp-NEVPLYGEQELHARLSMMLAGREAELMAF--GNTTSGASDDLKRASELAIE 534
WP_011831660 470 RA-GAGNVERVSIEPRGGALGATYVSRd-NEDPLYAEGELSGRLAMLLGGREAELAIF--GDVSSGASDDLRRATELAIS 545
WP_011194261 426 LTPGADPVQKVTIIPRGRAGGFTLTTPe-EDQMLYTRSELEARLKMLLGGLAAEEVLL--GERSTGAQDDLRRATQVARE 502
WP_104022665 465 VACPEDKLHKVTIEARGRTLGAAHFAPd-VDRHLHTRRYLLGLIAKALGGRAAELEFFgpEAITSGAGGDLVQATNVARR 543
WP_099511418 433 LLPASDKVHSATIIPHGQALGLVMRLPd-HDRFCIPVEKLEADLIVAMGGRAAEEVVFgpKKVTTGAASDIAHATNIVTK 511
WP_011491062 464 LLg-TGVLEEVTILPRGGALGVALITKa-QDKHLYRESEIRNEIQVLLGGRNAEIISF--SEASSGAASDLQEASRISLD 539
WP_129893287 634 MVTRWGMSEQVGVVFADyQAEgdyslnmrglrpdempaqaQSlvldadgnyrlngvptnrhpythamAVAatRShTSSSG 713
WP_085938655 631 MVSSMGFSSQFGLLSLA-GVP-------------------DAl----------------------------------VGP 656
WP_050742281 500 MVTRWGMDADIGPLRLE-HAv--------------------------------------------------------EGE 522
WP_012871440 507 MVQRYGMGKRFGLLSTG-Ag-------------------------------------------------S--DL-QQLSP 533
WP_053013706 535 MVSSMGFSTEFGLLSLQ-GVP-------------------EKl----------------------------------VGP 560
WP_011831660 546 MVSTLGFSPNFGLLSMA-GVP-------------------KEl----------------------------------LGP 571
WP_011194261 503 MISRYGMGQSVGLMAVP-DT-----------------------------------------------DWP--GV-QNLSQ 531
WP_104022665 544 MVADFGMSEQVGLVSAD-AS-------------------------------------------------A--QG-GQPSS 570
WP_099511418 512 MVTEWGMSPAIGMVRVS-H----------------------------------------------------------SGE 532
WP_011491062 540 MVSKFGFNADGNLFSLA-ALP-------------------SQ-----------------------------------YAG 564
WP_129893287 714 TMSSLIDAEVQRILNEGRAIAREILTQHNQQLTSLAKTLMEEEQLNREQFEQLLDA 769
WP_085938655 657 HIQERALGEARAMLEAAQRACRETLERHCHVLHAVTAALLKDDTVSGALLREMLPA 712
WP_050742281 523 ESLRRADGAMRALVAAAERAARALLEARRSGLERLAAALLERERLEGPEVEALLEL 578
WP_012871440 534 QSAYTAEQEALELVQQAHQVALDVLRAHADDLERVAQRLLEVETIDGEELETLISP 589
WP_053013706 561 HIQEKVLAEAKVLLDKAQHLCRDALHHHRDALNALTDALLREDTVSGPLLQRLLPA 616
WP_011831660 572 QTQEQALQEARELLSAAQRRAREILTANASALHQLAAALLEREIVGGEPLRQILSP 627
WP_011194261 532 ESAAAIEREVQALLDRLYREVRSLIETNRDRLVALVVELSDRETLDGDDVRRILSA 587
WP_104022665 571 QLMSQIDTAVRALIREQADRAEALVREHRAAVEAVAQALLEKDVLSADEVITIARA 626
WP_099511418 533 SLPREVEQEIRRIIDEMYEAAKACVQDNRDALDALTEALLEHETIDGDEVREIVSR 588
WP_011491062 565 LQMKGAIEHANVLLKELNESCHALLHAYEPVLRAIADELLEQETVPGETVYRLIRE 620
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