Conserved Protein Domain Family
UvrC

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COG0322: UvrC 
Excinuclease UvrABC, nuclease subunit [Replication, recombination and repair]
Statistics
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PSSM-Id: 440091
Aligned: 697 rows
Threshold Bit Score: 472.301
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_006293110   2 StqgfrpvspvssvsgaekargvnkngapllgdsrDlfRPKTSDIPAQPGVYKWRDANGRVIYVGKAKNLRNRLSNYFQP 81 
WP_041762774   1 Mlan----------------------------pskHi-EQKLALLPAEPGSYQMKDKNGKIIYVGKAKNLKNRVRSYFKQ 51 
WP_118989740   1 Mtdqsntpr------------------esraeikaNi-EAKLTLLPDLPGCYIMYNQADEIIYVGKAKNLKNRVRSYFRG 61 
WP_013625124   1 ---------------------------------meQi-KNKLGLLPAKPGVYLMKNNKNRIIYVGKAKILKNRVKSYFHG 46 
WP_003668235   1 Mas-------------------------------eHl-EHKLALLPDKPGCYLMKNINDQIIYVGKAKNLKNRVRSYFKS 48 
YP_193829      1 Mat-------------------------------eLi-ENKLKLLPEKPGCYLMKDINGTVIYVGKSKNLKNRVRSYFKS 48 
WP_002817195   1 Mas-------------------------------eLi-EQKLALLPSQPGSYQMKDKNGKIIYVGKAKNLKNRVRSYFKA 48 
WP_015042456   1 ---------------------------------mdLl-QKKLKLLPDNPGVYLMKNAAGKIIYVGKAKVLKNRVRSYFTG 46 
WP_041534601   1 Mas-------------------------------dHi-ERKLALLPDRPGCYQMKNLNSQIIYVGKAKNLKNRVRSYFKS 48 
WP_005685661   1 Mas-------------------------------aHi-EHKLSLLPDLPGSYQMKDINGKIIYVGKAKNLKNRVRSYFKS 48 
WP_006293110  82 LnrLHPRTQSMVLIARSLEWTLVGTELESLTLEYTWIKEFDPRFNVVFRDDKTYPYLAISiGDEVPRIWVTRNRNKRGTR 161
WP_041762774  52 D--HDGKTAELVGNIVDFDFIVTNSDKEAFLLENELIKKYKPYYNIRLKYGTGYPYIKIT-KERNPKMALVNEVKKDGGF 128
WP_118989740  62 A--HDTKTTKLVSEIHHFETIITNSDKEALILEINLIQEYKPQYNIKLKNGTMYPYLKIT-KEKDPQLIITSDVVKDGGQ 138
WP_013625124  47 S--HDQKTQQLVSQIADFEYIVTSSELEALVLECNLIKKYYPRYNIMLKDDKTYPYLLLT-SEKHPRILVTRNVNRKMGK 123
WP_003668235  49 S--HTGKVAKMVSEVADFETIVTSTNKESFLLEITLIQKHQPYFNIKLKKGTGYPYIKIT-NERDPQIKIVSKIKKDGGY 125
YP_193829     49 K--QVGRRAELVREIRDYDIITVSTDKEAFLLEITLIKKYQPYYNVQLKQGTGYPYIEIT-REHDPQTRLTSVVHKDGGY 125
WP_002817195  49 E--HTGKTAELVANIHDFEFIVTNSDKEAFLLENTLIKRYRPYFNIRLKFSGSYPYIEIT-NERDPRLILANTLKHDHGT 125
WP_015042456  47 S--HDQKTQKLVSEITDFEYILTSSEVEALLLECNLIKKHDPYYNIMLKDDKSYPYILIT-SEKHPRIIVTRKVSKKAGK 123
WP_041534601  49 S--HDGKTARLVSEIADFDYIVTSSDKEAFLLEITLIQKYQPYFNIKLKKGTGYPYIKIT-NERDPQMKIVSSIRKDGGF 125
WP_005685661  49 S--HDGKVAAMVAQVADFDYIVTSTNKEAFLLEITLIQKYQPYYNIKLKKGTGYPYIKIT-NERDPKIEITGTIRKDGGY 125
WP_006293110 162 YFGPYAKVWNMRHALDSLLNAYPVRTCTQSvfhkaqvTGRPCLLAYIGKCSAPCVGRISLEDHRAMCEQVVGILTGRlGP 241
WP_041762774 129 YFGPYPNVYAAQETLRFLEKNYPLRRCNGY-------QGRPCLYYNMGQCLGPCWQDVSVEEYEEQISRIKHFLDGN-TA 200
WP_118989740 139 YFGPFPNVHAATNTQQVLHRAYPLRRCPKN-------EKRACFYYHLGQCIGCCDHEVSQEEYAEQISKIRRFLNGD-VA 210
WP_013625124 124 YFGPYPNATAAKETARLLNRVFPLRKCTHI-------PHEPCLYFHIGQCLGPCINQLNPEQYQDVLDKITSFLKGN-QK 195
WP_003668235 126 YFGPYPNVYAAEETMHFIQKVYPLRRCNGY-------QGRPCLYYHMGQCLGACFKEVPKSDYEEQIKKIKSFLSGN-TA 197
YP_193829    126 YFGPYPNVYAAQATLKFIRKVYPLRRCHGY-------QGRPCLYYHMGQCLGACFKKVPQKEYDEQIKKIKSFLNGD-IT 197
WP_002817195 126 YFGPYPNVYAASETLHFLEMTYPLRRCNGY-------QGRPCLYYSMGQCLGACWRTVPQEEYQKNIDAITRFLNGE-TG 197
WP_015042456 124 YFGPYPNATAARETARLLNRLLPLRKCSQI-------PTKSCLYYHIGQCLGPCIHPIEPEQYQEVLDKATMFLRGN-QK 195
WP_041534601 126 YFGPYPNVYAAEETLHFLEKVYPLRRCNGF-------QGRPCLYYHMGQCLGACFKEVPEEDYKEQIVKIKSFLNGN-VS 197
WP_005685661 126 YFGPYPNVYAAQETMHFIQKVYPLRRCNGY-------QGRPCLYYHMGQCLGACFRTVPEKEYTDQIARIKRFLNGN-VS 197
WP_006293110 242 SYAKKLTADMKQASADLDFERAARLRDQISALSSVLEQNSVVFDTDVDADIFGLASDELEASVHCFFVRAGTIRGERSWS 321
WP_041762774 201 SVKKAIAEKMQAAAATLEFERAADLRDQLKYIDETVESQRVLSKDTTPRDLFNYYLDKGWMTVEVFFLRQARLIRQFKQT 280
WP_118989740 211 EIKQALQEKMHRAAENMEYEQAADFRDQINYIETTVERQSIMSEDYDNMDVFNYSMDRGYLSIQVFMLRQGSILKRKAAI 290
WP_013625124 196 DIIRWLEEKMNSASANLQFENAKEYRDLIQAIQTISEKQNITLNDFRNRDFVSYRFSDELLCIQIFYFRQGKLVARDNFL 275
WP_003668235 198 TVKRQLTKKMQRAAENMEFERAAEIRDQLHYIEVTVEKQKIISNDKTPRDLFNFYMDKGWLSIQIFFIRQARLMKREKRL 277
YP_193829    198 SVKQDLTTKMEKASENLEFERAAEIRDQLKYIEETVEKQKIISNDNTQRDIFNYYVDKSWISIQIFFLRQAKLLRRETRM 277
WP_002817195 198 KAISDIKKKMKRASDSTEYELAADFRDRLKFIDQTVESQRVLQNDHTPRDLFNFYMDKGWMTIEIFFLRQGRLLRQQKET 277
WP_015042456 196 SIINWLEGKMTKAAEALQFEAAREYRDLIQDLKTISEKQNITLSDLRNRDIVAYAFNEELMNIQVFCFRQGKLVTRDSFF 275
WP_041534601 198 SVKKSLQQKMMQSAEKLDFERAAEIRDQINYIEITVEKQKIISNDRTPRDLFNFYFDKGWLSIQIFFIRQSRLIKREKKL 277
WP_005685661 198 KAKASLTAKMERAAKNLQFERAAEIRDQLYYIEQTVEKQKIISTDNTTRDLFNFYMDKGWISIQVFFIRQARLMKRESRL 277
WP_006293110 322 VERvedIDDSQLMADLISQVYSDLMEenkreegvsiavstsrdalapsqqvtaddarsraqatrrrrsrqeetgrddlls 401
WP_041762774 281 FSVvgsED--EEVINFIQQFYSQRNIq----------------------------------------------------- 305
WP_118989740 291 FPSygnPE--DEVTTFIARFYQEEAQl----------------------------------------------------- 315
WP_013625124 276 FPYyeePE--EAFVSFLLQYYDNKNK------------------------------------------------------ 299
WP_003668235 278 FPIvdtAV--EEMTSFILQFYNRRNNi----------------------------------------------------- 302
YP_193829    278 FPLtdaADPEDAFTSFIVQFYGQKNRi----------------------------------------------------- 304
WP_002817195 278 LALadsVK--EELESYIQQFYSQKNAq----------------------------------------------------- 302
WP_015042456 276 FAYydePE--ESFLSFLVQYYTDEMV------------------------------------------------------ 299
WP_041534601 278 FPVvndAE--EELTSFVLQFYNNKNKi----------------------------------------------------- 302
WP_005685661 278 FPVvntAK--EEFESFILQFYSRKNNv----------------------------------------------------- 302
WP_006293110 402 pisaVPrEVILPVKPdRPEELEEWLtslrgsAVSITtaSRGEKKtLMDRALTNAQQSLARLKASRmtdiGMRTQALNDIA 481
WP_041762774 306 ----KPnEVLVPHGI-NTKALSEIL------AVPVRipIRGEKRdLLDLAKKNAQIALEEKFRLMqlneKKTTGAMREIT 374
WP_118989740 316 ----KPrAILVPSDV-DHELLEDFL------DLPVStpLRGKKRsLLELAEKNSKIQLDEKFRLIemsdKKTKGAVQELA 384
WP_013625124 300 ----IPdEICLPE-N-KSPLLNHLL--------PVTvpKRGKTLeIIKLATNNAETVLQERTSLEkiktEKTLLALQGLG 365
WP_003668235 303 ----LPhEILLPKGL-PNKEISEIL------GVPVRtpVRGEKRdLLAMAHENAQLSLDEKFRLLemdqSKTTGAMKEIT 371
YP_193829    305 ----LPkEILIPSGF-DDDTLAEVL------NVAVRtpQRGQKKsLLDMAKDNAKLKLDDKFRLLelgnRKTKGAQKEIF 373
WP_002817195 303 ----KPkEVLVPKNV-DTKLLAETL------EIPVRtpVRGEKRdLLKLAAKNARITLEDKFRLMelneEKTTGAMKEIT 371
WP_015042456 300 ----IPdEICIPE-I-QSTAVMDIL--------PLTipKKGKTKqLLAMAASNAETVLKEKMDLEkdknEEIQKTMAGLC 365
WP_041534601 303 ----LPnEVLIPKGF-DNTVISEIL------GVPVRtpQRGEKRdLMDLARENAQITLEEKFRLMelddSKTVGAMKEVT 371
WP_005685661 303 ----KPrEVLVPAGL-DNKVLADIL------EVPVRtpQRGEKReLMALAAKNSKIKLEDKFRLMeldnRTTVGAMKELM 371
WP_006293110 482 QALDLAEaPLRIECYDISNASgGGYQVASMVVFEDGMAKKSQYRHFAIR---Ga----DgqgALDDTSALYETLTRRFKH 554
WP_041762774 375 AALNIPM-GHRIEAFDHSHTQ-GVEIVSAMVVFDDGVPNKDLYRKYKIK---Sv----T---HADEWSETQEVIRRRYSR 442
WP_118989740 385 ELLYIPQ-AEYIEAFDHSNTQ-GSNNVSGMVVYRHGKPERKNYRKFKIK---Sf----E---GADEFAATQEVIRRRYSR 452
WP_013625124 366 ELLDIDP-PQIIEAFDISSIS-GTNIVGGMVRFVQGKPCRSHYRKFNID---Ss----S---VNDDTSSMKQVVFRRYDR 433
WP_003668235 372 DALGLPE-GHRIEAFDHSHIQ-GADPVSAMVVFINGEPAKNFYRKYKLK---Tv---iN---HADEAASTREVIRRRYSR 440
YP_193829    374 DALGLPY-GHVIESFDHSHIQ-GADPVSALVVFKDGEPDKTSYRKYKLK---GevehqN---GGDEVRNTREVVRRRYGR 445
WP_002817195 372 DALKIPH-GYRFEAFDHSNTQ-GSNYVSALVVFEDGLPNKNLYRRYKLR---Tp----T---GQDEAKATFEVITRRYTR 439
WP_015042456 366 ELLGIAQ-ADTIEAFDISGLF-GSNIVGGMVQFKAGKPFRANYRKFNIA---Pl---aN---NNDDTAYLKHIIGRRYSR 434
WP_041534601 372 NALGIPT-GHRIEAFDHSHIQ-GADLVSAMVVFTDGKPDKKMYRKYKLN---Tv----D---HADEAASTREVIRRRYTR 439
WP_005685661 372 AALKLPM-GHVVEAFDHSHIQ-GADPVSAMVQFVDGQPAKNNYRKYKLDadkTh----N---GADEAANTREVIRRRYTR 442
WP_006293110 555 GNVAGDsgqsmedekrsqtllssqsldhrqeaqasgsasaatrrhfaYKPNLIVVDGGLPQVNAAAQALE-DLGItDVHV 633
WP_041762774 443 ILKEGG-----------------------------------------DMPDLILMDGGEIQLHAAKEVLVdELGLtHVPI 481
WP_118989740 453 LLREEK-----------------------------------------PLPDLILMDGGKIQIRAARDVLEnELGI-AIPV 490
WP_013625124 434 LLSENH-----------------------------------------QIPDLILLDGGKGQITAALNSLD-VLGL-SIPL 470
WP_003668235 441 LLKENK-----------------------------------------PMPDMIFMDGGEIQMDAAKDVLEnELGL-EIPV 478
YP_193829    446 LLREHK-----------------------------------------KMPDLILMDGGQIQVDACEDVLRnELNL-NIPV 483
WP_002817195 440 LRDEGQ-----------------------------------------MYPDLILMDGGEIQLHSAEAALR-KLDI-DIPV 476
WP_015042456 435 LQREES-----------------------------------------AMPDLILVDGGKGQVKAALDALK-ELRL-TIPV 471
WP_041534601 440 LLKEHS-----------------------------------------SLPDLVLMDGGEIQLNAARDVLVnELGL-TIPV 477
WP_005685661 443 LLKEHA-----------------------------------------ALPDLILMDGGEIEMNAAKDVLEnELNL-DIPV 480
WP_006293110 634 CGLAKKLEE----IWLPH-----EEYPLIMKRQSEGMYLMQRVRDESHRFAITYHRKKRSKGSLRSALDSIEGIGLSYQK 704
WP_041762774 482 AAMVKNDKHktadLIDGK-----TGDVVVLNKQSEGFFLIQRVQEEVHRFAINFHRQLRSKNSLASRLDMIDGVGPKTRQ 556
WP_118989740 491 AGMVKDDRHktasLMDGY-----SEELVEVDPRSEAFHLLQRIQEEVHRYAISYHRTLRSKTTFGSILDDIPGVGPKTRT 565
WP_013625124 471 AGMVKNEEHttrtLINAD------GAEIDLAKYPDAFRLIQQIQEEVHRFAITFHRQKRIKDLTSSELDLIPGVGPKRKR 544
WP_003668235 479 VGMVKNDKHqtadLLFGD-----DDHHINLNPRSQGFYLVQRIQDEVHRFAITFHRRVHTKHSLSSRLDEIKGVGPRTRT 553
YP_193829    484 AGMVKDDKHrtnhLLFGDpingiPLKLIPLDPKSEGFYLMTRIQDEVHRFAITFHRRRHAKNALSSRLDSIKGIGPKSRN 563
WP_002817195 477 AAMVKNDKHqtadLLNSR------GENLFLDPHSQGFYLLQRIQDEVHRFVITFHRQLRTKTNLSSRLDEIAGIGPKSRV 550
WP_015042456 472 AGMVKNDRHetrsLINQT------GRELSIDTRVEVFYLIQRIQDEVHRFAITFHRQQRIKNMTASELDGIPGIGPKRKR 545
WP_041534601 478 AGMVKNDKHktsdLLFGE-----QDMRVQLDPKSQGFYLIQRIQDEVHRFAITFHRQLHAKHSLSSSLDSINGVGPKTRT 552
WP_005685661 481 AGMVKNNKHktaaLLFGH-----ADEMINLDPKSQGFYLLERIQDEVHRFAITFHRQLHAKNSLASRLEGIKGVGPKTRL 555
WP_006293110 705 RLLNHFGSVKAMRQATVQELQEVrGVGAKKAEAIYQSLHP 744
WP_041762774 557 KLLREFGSLPKIAAASITELQAI-GVNEKLARVIHMSLKA 595
WP_118989740 566 KLLKHFKSLKRIREATTEDITAL-GIPKPTAERIIESLNE 604
WP_013625124 545 DLLLNLGSLANIKQSSVEDFRKI-GLPENIALAIYSYFHG 583
WP_003668235 554 KLLKKYGSITKIAQASVDEIHSL-GINRPTAQLIKVSLQK 592
YP_193829    564 KLLRNFGSLKKIKEASIEDLRAA-GLTLPQAQTVKLML-- 600
WP_002817195 551 KLMRRFGSLPKIADASIEDIEAL-GIGEKVATLVKVSVSA 589
WP_015042456 546 MLLRTFDSLDEIKNAAPEEFIKS-GLSAVAAQEVYNHFHH 584
WP_041534601 553 KLLKKFGSISKIGNATVKEITSL-GISEKVAKTVKVSVAA 591
WP_005685661 556 KLLRKFKTITKIKEAPLEDIQEL-GISKRVAQALKLSLTA 594
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