1Y64,2Z6E,3O4X


Conserved Protein Domain Family
FH2

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pfam02181: FH2 
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Formin Homology 2 Domain
Statistics
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PSSM-Id: 396655
Aligned: 40 rows
Threshold Bit Score: 265.288
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1Y64_B         22 FEKYPRPHKKLKQLHWEKLD-CTDNS------------IWGTGKAEKFADdlyeKGVLADLEKAFAAREIKSLA------ 82   baker's yeast
Q9SRR2        469 EGTTDRPKPKLKPLPWDKVR-PSSRRt----------nTWDRLP--------------------YNSSNANSKQrs---- 513  thale cress
O22824        438 EKKVETMKPKLKTLHWDKVR-ASSSRv----------mVWDQIKSNSFQV----NEEMIETLFKVNDPTSRTRD------ 496  thale cress
Q19479        614 SAVVYRKQKKTAFVRWPKLTmQMQDAg----------tVFNDSLCVDFN-----EDERTKMEEVFEEAPVKQLNrkiags 678  Caenorhabditi...
Q9TYU9        127 FLPKKEKKTKTRTVQWSKIN-ASVVQdd---------sVWGKLAKASNV-----DIDFDLLDNFFGIESLAVSGaae--- 188  Caenorhabditi...
Q9C0D6         87 GYSHLGKKKRMRSFFWKTIP-EEQVRgk--------tnIWTLAARQEHHY----QIDTKTIEELFGQQEDTTKSslprr- 152  human
NP_001246683  642 gnNTIKKNKKTVKLFWKEVR-EDMIPqvv------gktIWDELPDA--------NVDTQKLEHLFESRAKDLMTk----- 701 
Q2V2M9        883 GQPTFTKKKKTIRLFWNEVR-PFDWPcknnr--rcrefLWSKLEPI--------KVDTSRLEHLFESKSKELSVsk---- 947  human
Q9Y613        616 DSSALPTKRKTVKLFWRELK-LAGGHgvsasrfgpcatLWASLDPV--------SVDTARLEHLFESRAKEVLPs----- 681  human
Q9JL04       1139 RKQLIEPCRPMKPLYWTRIQ-LHSKRdss------pslIWEKIEEP--------SIDCHEFEELFSKTAVKERKkpi--- 1200 house mouse
1Y64_B         83 -------------------SKRKEDLQKITFLSRDISQQFGINLHMYsSLSVADLVKKILNCDRdfLQtpsvveflskse 143  baker's yeast
Q9SRR2        514 -----------------lsCDLPMLNQESKVLDPRKSQNVAVLLTTL-KLTTNDVCQALRDGHYdaLG------------ 563  thale cress
O22824        497 -------------------GVVQSVSQENRFLDPRKSHNIAILLRAL-NVTADEVCEALIEGNSdtLG------------ 544  thale cress
Q19479        679 vgrafgkslrattsssefnPMSARSPTNPQVLVSPKALTIEILIKKLkPMEFTQLIEKLDANDTegIK------------ 746  Caenorhabditi...
Q9TYU9        189 -----------------vvKKSTRKDAHVELLTAKRSQNVAIMLKQF--KNIDELIDDVSQNKPv-AE------------ 236  Caenorhabditi...
Q9C0D6        153 --------------grtlnSSFREAREEITILDAKRSMNIGIFLKQF-KKSPRSIVEDIHQGKSehYG------------ 205  human
NP_001246683  702 ------------------kQQELNKSKEIIVLDHKRSNAINIAITKL--PPPRAIKTAILKMDAtvVT------------ 749 
Q2V2M9        948 ------------------kTAADGKRQEIIVLDSKRSNAINIGLTVL--PPPRTIKIAILNFDEyaLN------------ 995  human
Q9Y613        682 ------------------kKAGEGRRTMTTVLDPKRSNAINIGLTTL--PPVHVIKAALLNFDEfaVS------------ 729  human
Q9JL04       1201 ----------------sdtISKTKAKQVVKLLSNKRSQAVGILMSSL-HLDMKDIQHAVVNLDNsvVD------------ 1251 house mouse
1Y64_B        144 iIEVSVNLArNYAPYSTDWEGV--RNLEDAkppekdPNDLQRADqIYLQLMVNlESYWGSRMRALTVVTSYEREYNELLA 221  baker's yeast
Q9SRR2        564 -VELLESLA-RVAPSEEEEKKL--ISYSDDs-----VIKLAPSE-RFLKELLN-VPFVFKRVDALLSVASFDSKVKHLKR 632  thale cress
O22824        545 -PELLECLL-KMAPTKEEEDKL--KELKDDdd--gsPSKIGPAE-KFLKALLN-IPFAFKRIDAMLYIVKFESEIEYLNR 616  thale cress
Q19479        747 -VDLMTTLN-NNFPDKVELDPF--L--KVE------YATLTHASdQFCWHIAR-NKHLRLRIELFISKENVTAEIGKFQS 813  Caenorhabditi...
Q9TYU9        237 -IDALQNLF-GMLPQSEEEEAL--RRYTGD------ISLLSPPS-SFFYRLVQ-IQFYRLRIETQIFLSDFSRLMRELAP 304  Caenorhabditi...
Q9C0D6        206 -SETLREFL-KFLPESEEVKKL--KAFSGD------VSKLSLAD-SFLYGLIQ-VPNYSLRIEAMVLKKEFLPSCSSLYT 273  human
NP_001246683  750 -REGIDKLL-NMLPTDEERGKIqeAQLSNP------ELPLGSAE-QFLLTLAS-ISELEARLKLWAFRLDFDNSEKEIAE 819 
Q2V2M9        996 -KEGIEKIL-TMIPTDEEKQKIqeAQLANP------EIPLGSAE-QFLLTLSS-ISELSARLHLWAFKMDYETTEKEVAE 1065 human
Q9Y613        730 -KDGIEKLL-TMMPTEEERQKIeeAQLANP------DIPLGPAE-NFLMTLAS-IGGLAARLQLWAFKLDYDSMEREIAE 799  human
Q9JL04       1252 -LETLQALY-ENRAQSDELEKI--EKHSRSskdkenAKSLDKPE-QFLYELSL-IPNFSERVFCILFQSTFSESICSIRR 1325 house mouse
1Y64_B        222 KLRKVDKAVSALQESDNLRNVFNVILAVGNFMNDTS---KQAQGFKLSTLQRLTFIKDTTNSMT--FLNYVEKIVRL--- 293  baker's yeast
Q9SRR2        633 SFSVIQAACEALRNSRMLLRLVGATLEAGMKS-------GNAHDFKLEALLGLVDIKSSDGRTS--ILDSVVQKITEseg 703  thale cress
O22824        617 SFDTLEAATGELKNTRMFLKLLEAVLKTGNRMNIGTn-rGDAHAFKLDTLLKLVDIKGADGKTT--LLHFVVQEIIKfeg 693  thale cress
Q19479        814 QIELLQTGCQ-LARGEIVQVLLRKCLQYGNYLNQGSm-fAEAAGFQFSYLIQLLQMKGKGQHTSvrLVDLIVAYCDL--- 888  Caenorhabditi...
Q9TYU9        305 NVEILIRTSQEILTSPTLPRLLLIFVNMGNYLNGNNs-qGNAFGFTLNSLWKLIDLKGNKQEFS--LLHLLVTC------ 375  Caenorhabditi...
Q9C0D6        274 DITVLRTAIKELMSCEELHSILHLVLQAGNIMNAGGy-aGNAVGFKLSSLLKLADTKANKPGMN--LLHFVAQEAQK--- 347  human
NP_001246683  820 PLMDLKQGIEILRQNRTFRSILSTLLSVGIFLNG-----APVKGFQIEYLAKVPEVKDTVHKHS--LLHHLCHMVME--- 889 
Q2V2M9       1066 PLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNG-----TNAKAFELSYLEKVPEVKDTVHKQS--LLHHVCTMVVE--- 1135 human
Q9Y613        800 PLFDLKVGMEQLVQNATFRCILATLLAVGNFLNG-----SQSSGFELSYLEKVSEVKDTVRRQS--LLHHLCSLVLQ--- 869  human
Q9JL04       1326 KLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNAGNktrGQADGFGLDILPKLKDVKSSDNSRS--LLSYIVSYYLRnfd 1403 house mouse
1Y64_B        294 -------------------------------NYPSFNDFL-SELEPVLDVVKVSIEQLVNDCKDFSQSIVNVERSVEIGN 341  baker's yeast
Q9SRR2        704 -----------------------------ikGLQVVRNLS-SVLNDAKKSAELDYGVVRMNVSKLYEEVQKISEVLRLCE 753  thale cress
O22824        694 arvpftpsqshigdnmaeqsafqddlelkklGLQVVSGLS-SQLINVKKAAAMDSNSLINETAEIARGIAKVKEVITELK 772  thale cress
Q19479        889 -------------------------------ATAEVEEVQ-SRMGSVRP---LNLKDLEDVVGQVQRSIRKLEGQLRSSS 933  Caenorhabditi...
Q9TYU9        376 -------------------------------EPDLVAHLQ-EELSTLKDASQISFDEIKISLKTLRDGRCKLEKQLETCS 423  Caenorhabditi...
Q9C0D6        348 -------------------------------KDTILLNFS-EKLHHVQKTARLSLENTEAELHLLFVRTKSLKENIQRDG 395  human
NP_001246683  890 -------------------------------SSSDTSDLY-SEIGPITRASKADFTDLAHNLNQLEAECKACWDRLKLIA 937 
Q2V2M9       1136 -------------------------------NFPDSSDLY-SEIGAITRSAKVDFDQLQDNLCQMERRCKASWDHLKAIA 1183 human
Q9Y613        870 -------------------------------TRPESSDLY-SEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLA 917  human
Q9JL04       1404 -----------------------------edAGKEQCVFPlAEPQELFQASQMKFEDFQKDLRKLKKDLKACEAEAGKVY 1454 house mouse
1Y64_B        342 LsdsskfhPLDKVLIKTLPVLPEARKKGDLLEDEVKLTIMEFESLMHTY---GEDSg---dKFAKISFFKKFADFINEYK 415  baker's yeast
Q9SRR2        754 EtghseehQWWKFRESVTRFLETAAEEIKKIEREEGSTLFAVKKITEYFh-vDPAKe----EAQLLKVFVIVRDFLKILE 828  thale cress
O22824        773 Qe-----tGVERFLESMNSFLNKGEKEITELQSHGDNVMKMVKEVTEYFh-gNS-------ETHPFRIFAVVRDFLTILD 839  thale cress
Q19479        934 E---------ETLIAAYEPFVNQTNEKLQNVQNGLSDLKARETELQVYL---CAg------NMTLQAIFETLEQSMKIVS 995  Caenorhabditi...
Q9TYU9        424 G---------ASFTQFLELIKIDCKFELDEFGANYDKLTELQYQLADYF---CENRn----TFQLDECLKIFNFLMNRLQ 487  Caenorhabditi...
Q9C0D6        396 E-----------LCQQMEDFLQFAIEKLRELECWKQELQDEAYTLIDFF---CEDKk----TMKLDECFQIFRDFCTKFN 457  human
NP_001246683  938 Kh-----dCPPPLKQKLVDFLADCAERIIILQIVHRRVMNRYRKFLLWLgmpQhs----vaESRPNEFCRTLSEFALEYr 1008
Q2V2M9       1184 Kh-----eMKPVLKQRMSEFLKDCAERIIILKIVHRRIINRFHSFLLFMghpPYAIr----EVNINKFCRIISEFALEYR 1254 human
Q9Y613        918 Kh-----eLAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLgytPQAAr----EVRIMQFCHTLREFALEYR 988  human
Q9JL04       1455 Qvss--aeHMQPFKENMEQFISQAKIDQESQEAALTETHKCFLETTAYY---FMKPklgekEVSPNVFFSVWHEFSSDFK 1529 house mouse
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