2QZ9,2GYY,3VOS,3UW3


Conserved Protein Domain Family
Asd

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COG0136: Asd 
Aspartate-semialdehyde dehydrogenase [Amino acid transport and metabolism]
Aspartate-semialdehyde dehydrogenase is part of the Pathway/BioSystem: Lysine biosynthesis
Statistics
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PSSM-Id: 439906
Aligned: 718 rows
Threshold Bit Score: 214.125
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2QZ9_A         4 FNVAIFGATGAVGETMLEVLQE-REFP-VdELFLLASERSEGKTYRF-NGKTVRVQNVEE-FDWSQVHIALFsAGGELSA 79 
YP_169468      2 LKVGFIGWRGMVGSVLMSRMIEsKDFDcI-LPTFFSTSQVGQLPTGF-MQQYGALQDAYSiDQLSSMDILLScQGGEYTK 79 
WP_011283111   2 KNIGFVGWRGMVGSVLMNRMKEeNDFNyF-HSIFLSTSQIGEHAPNIqASQELLLQDACNiDLLNSLDIIITcQGSAYSK 80 
WP_012541678   2 KQVGIVGWRGMVGSVLLQRMIEeNDFDdI-SAHFFSTSSAGGVGPVI-NGKSDILKDANSlSALAEMDIIITcQGGDYTK 79 
WP_014354093   2 KYVGFIGWRGLVGSVLIQRMQEeNDFKyI-RPVFFSSSQNGRYKTII-NNKLNFIYHAFNlEILIELDIIVScQGNSYTK 79 
WP_014943222   2 LKMGFVGWRGMVGSVLIQRMLEeNDFNyI-EPIFFSTTKFGKTGPIY----ATKIQNAYDlNKLKKLNVIITcQGGDYTN 76 
WP_041068813   2 KNVALVGWRGMVGSVLMSRMIEeHDFDhI-NPVFFSTSQLNQSAPEFsGKSYGALQNAYDiDSLRQMDIVITcQGSDYTE 80 
WP_041062731   2 KNVGFIGWRGMVGSVLIDRMQEeKDFDmI-NPIFFTTSQYNNLAPNFsNKTNEKLKDAYNiDLLNSLDIIVTcQGGLYTN 80 
WP_045086229   2 FTVGFVGWRGMVGSVLLKRMIEdGDFKnI-NPNFFSTSQILHTGPQL-GKKKFILHDAFDiDALTAMDIIVScHSSNYTN 79 
WP_066283399   2 KTVGFIGWRGMVGSVLLQRMNEeGDFNnI-NPVFFTTSQYEEIAPNY-GQYQKKLLDAFSlDILKELEVIVTcQGGNYTN 79 
2QZ9_A        80 KWAPIAAEAG--VVVIDNTSHFRYDYDIPLVVPEVNPEAIAEFrnR--NIIANPNCSTIQMLVALKPIYDAVGIERINVT 155
YP_169468     80 EIHHKLREAGwqGFWIDAASTLRLDKDSTLVLDPLNHDQIINAidNgkKDFIGSNCTVSLMSLAIAGLLKEDLVEWVNSS 159
WP_011283111  81 IIYPKLRKIGwtGYWIDSASFLRMNDDAIIVLDPVNQVLIKQSinNgiKTFVGGNCTVSLMLMSLGGLFAHNLIEWVFAS 160
WP_012541678  80 AIYPALINHGwqGYWIDAASALRMDEKACIILDPVNRDNIDRAvkAgvKLFVGGNCSITLSLMGLAGLIKADLIEWMSVM 159
WP_014354093  80 IIHNRLRKLNwqGYWIDSASILRMHQNSCIVLEPVNRSIVKKKifQgyKDFIGSNCSVSLMLIALGGLFEKKLIEWVSVA 159
WP_014943222  77 RIYKSLRNTGwnGYWIDSSSKLRMDSNSIIVLDPINIKIIEQSlyLgiKNFIGGNCTVSLMLLSLGGLFQNNLIEWITSM 156
WP_041068813  81 KVYSTLRNTGwqGYWIDASSTLRMMNDAIIVLDPVNQSLIHRGldEgiKTFVGGNCTVSLMLMALGGLFNKKLVDWISVS 160
WP_041062731  81 KIYKKLLKTGwkGYWIDSSSTLRMKRESIIVLDPINYDLIINSlnKgiKTFVGGNCTVSLMLMALKGLFSENLIDWISVA 160
WP_045086229  80 IVYKKLIKNKwkGYWLDASSTLRMNNDAVIVLDPINSNLIYKYldMgiKTFIGGNCIVSIMLMTLGGLFKAKIIDWINSI 159
WP_066283399  80 QIYHKLLDIGwsGYWIDASSSLRMRDDSIIVLDPVNRQHIDRGlnSgiKTFVSGNCTVSLMLMALAGLFVENLIEWISVS 159
2QZ9_A       156 TYQSVSGAGKAGIDELAGQTAKLLN---------GY---PAE--------------TNTFSQQIAFNCIPQIDQFMDNGY 209
YP_169468    160 TYQAISGAGAAAMQELLQQTSLLSKid-----nrDEdilIREkilrelskdsskipQQKTVQTLAYNLLPWIDVGMPSGQ 234
WP_011283111 161 TYQAASGCGARAMRELLIQMGQVYNtvtdlltspSMailDIEhiitkfs-ktdsllVDCFKVPLIGNVIPWIGDYMYNGQ 239
WP_012541678 160 TYQSASGAGAKQVRELIAQSAYISQhlsadeltaSGsvlPLVnkvseli-nsagmpVENFGVPLMGSIIPWIDSDLGDGN 238
WP_014354093 160 TYQAATGAGSNYTRKLLLQINKIHSllgnklnnpAFdilKIEnkihkli-knknifQNSI---LAYNIMPWIGKKIKFQQ 235
WP_014943222 157 TYQAASGAGSKHMIELLNQMRILGNivkk--nnnAKsilEIDskitkf---mgklpIKNFGAPIAGSLMPWIDKKMDNGQ 231
WP_041068813 161 TYQAASGGGANHIRELLMQMGVLYNsvstelqdsASiilNIErnvtdlarrkdilpTNHIGTILAGSLIPWIDKEMQNGQ 240
WP_041062731 161 TYQAASGGGAKHIHELLVTMGQIYNsvakslndpQMsilNIEkivtnli-nsrrlkTDVFGVPLAGSLIPWIDILLKNGQ 239
WP_045086229 160 TYQAASGAGSQYMRELINQMYNISNifyndfnsvDSkilDIDkklnrvm-ysgilqTKKINLPIAVSLLPWIDQQINNGQ 238
WP_066283399 160 TYQAVSGIGARNMRELLLQMGELYSkvsddlqnvAIsilSIEkkittfi-rsgkmiAKEFSIPLVSNLIPWIDKKLINGQ 238
2QZ9_A       210 TKEEMKMVWETQKIFND--PSIMVNPTCVRVPVFYGHAEAVHVETRAPIDAEQVMDMLEQTDG-IELF-----RGADFPT 281
YP_169468    235 TKEEYKAATELNKILDTk-KTIPVDGICVRVPSLRSHSQALTVKLRQKLTIEEIKQKISQGNEwVKVIdnnkeDTLKYLT 313
WP_011283111 240 TQEEWKGQAETNKILNTs-KIITVDSLCVRVGSLRCHSQAFVLKLKKDICLKEIEELLQSHNKwVEVIsndvtQSLNKLT 318
WP_012541678 239 SREEWKGEAETNKILGLapGTIPVNGLCIRVGVIRCHSAAITLKLKREVSEAEFAELVTHSHPwVNYVrnnkqESVSQLT 318
WP_014354093 236 SLEEKKYQEEVFKILNLn-HVIPIDGTCVRVGSLRCHSQSFTIKLKKNVSILEIEQILSNHNAwVKIIpddpeKIINDLT 314
WP_014943222 232 SKEEWKGNVETNKILGCspNTIKIDGICVRIGAMRCHSQAFFIKLKKNIPIKDIESIIKEHNPwVKVIknnstQSLKKLT 311
WP_041068813 241 SREEWKGQVETNKILGTs-KIIPVDGICVRVSSLRCHSQAFTIKLNKNMPLEDIKEILASHNKwVKVIpnnyrSTTKELT 319
WP_041062731 240 TKEEWKGQEETNKIINSk-KIIPIDGVCVRIGSIRCHSQAFTIKLKKDIDLKDIEKILLNNNQwIKIIpnnqeSTINQLT 318
WP_045086229 239 SREEWKSNIETNKILGYlqNTITIDGICVRIGTMRCHSQALIIKLRKNIPINDIETIINEHNDwVNIVpnnkkASIEYLT 318
WP_066283399 239 TYEEWKGQAETNKILNTh-TIIPIDGLCVRIDALRCHSQAIILKLKKNISIRNIEQILESHNDwVCVIpnepeLTIKKLT 317
2QZ9_A       282 QVrDAGGKDHVLVGRVRNDISHHSGI-NLWVVADNVRKGAATNAVQIAELLVR-D 334
YP_169468    314 PQ-ANSGTLDIAIGRIKSSLLADDIF-HCFTVGDQLLWGAAEPLRRVLNIIKI-- 364
WP_011283111 319 PV-MVSGTLNIPIGRLRKLHAGNKYI-SAFSVGDQLLWGAAEPLRRILRQLL--- 368
WP_012541678 319 PA-AISGSLQVGIGRYKKMSLNNEPVySVLTVGDQLLWGAAEPLRRMLNILLG-K 371
WP_014354093 315 PV-SVSGSLYIAIGRIRKLSIGNKYL-SIFTVGDQLLWGAAEPLRCVLNQLII-- 365
WP_014943222 312 PA-AVTGTMSIPIGRLRKASIGSKFL-TAFTVGDQLLWGAAEPIRRMLKILVN-R 363
WP_041068813 320 PV-AVSGSLSIPIGRLRKLNIGPKYL-SAFSVGDQLLWGAAEPLRRMLRLIID-- 370
WP_041062731 319 PV-AVTGKLTIPIGRLRKLNMGKKYL-SAFSVGDQLLWGAAEPIRRILQILIKlT 371
WP_045086229 319 PA-SVSGNIKILIGRMRNLIIGDEYL-TAFSVGDQLIWGAAEPIKRMLNIIIN-Y 370
WP_066283399 318 PT-AVTGTLNIPIGRLRKLNMGKRYL-SAFTVGDQLLWGAAEPLRRMLKLL---- 366
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