7O56,2IRF,2O6G,2O61


Conserved Protein Domain Family
IRF

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pfam00605: IRF 
Interferon regulatory factor transcription factor
This family of transcription factors are important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. Three of the five conserved tryptophan residues bind to DNA.
Statistics
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PSSM-Id: 459863
Aligned: 77 rows
Threshold Bit Score: 109.573
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7O56_A        25 KLRQWLIDQIDSGKY-PGLVWEN-EEKSIFRIPWKHAGKQDYNrEEDAALFKAWALFKGKFREGIDKP--DPPT---WKT 97 
XP_009020091   9 RLRDWLIQQANKNE---GASYYDdRDRNLIKIPWVHGSKKHWDsNVHCRIFKLWAEYSGRFiviiiinkkDPKI---WKS 82 
XP_002107832   5 VMTDWLKEILEENAV-EGIHYVN-GSKDTFAIKWVHASNKSYDpDCHGAIFKRWMKKSRKL----DKYksNYSM---WKT 75 
Q4H3B1        28 QFKPWLIEQISSGNY-PGLEWIDsEQQRVFKLPWTKKNYPGW--EDHHKIFKAWAEHRSFI-RNQKPPtqHVSL---MKS 100 vase tunicate
NP_001071953  26 RFTTWLVQQISSGNY-LGLEWVEgSNKRIFKIPWTKQNFPNW--AEHHKIFEDWALLRGRWNTVTGQPnqSFSQ---MKS 99 
3_pfamImport   1 PLRVWLLKRLNQAKYpDVVYWTD-KERGVFRILWTKKGNPNW--KQHFQIFEDWAKHRDNFRPDSPI---NYDQ---LKS 71 
XP_009857957  12 TLRNWLFNRLNEETYgDALKWDG-NNKGVFHILWTKKGDPNW--ENHFQIFVGWAKHKDRFDCNSPI---NYDK---LKS 82 
NP_001122338  10 PLRHWLVKKIEESAF-DGLEWVN-REEKTFKIPWTQKKYPNW--EKHCEIFKAWAKHRGSTNLGDPF---DFKK---LKG 79 
EEN50012      16 RLRKFLLEHLEWNDV-TGLSWMD-RSQGIFRIGWRHAGRDGYDpEVDGMIFRLWAELTGKHKPGQRE---DPTA---WKT 87 
EEN69106      23 RLRRFFVSHLDAGDV-PGVRWMD-RSTGLFRIDWPRGGRSGFNsEKDGLIFKLWAQKTGQWKPGDEK---NPTVwseWKT 97 
7O56_A        98 RLRCALNKSNDFEELV-ERSQLdIS-DPYKVYRIV 130
XP_009020091  83 NFRCALNSLSDVKEVK-ELSRIqNGvEGYKVYKII 116
XP_002107832  76 NFRCAINSLPDVMCLSaTDSQFaDD-DKYKGYKIF 109
Q4H3B1       101 NFRTILRKCRDLEEQTnLHQLGlQT-GNYKVYKVL 134 vase tunicate
NP_001071953 100 NFRTILRKCDYIKELHqSHQLGlQV-GNYKVYKLL 133
3_pfamImport  72 NFRNLIKKSSDFEELE--TVNNqQT-GNCKVFRVR 103
XP_009857957  83 NFRNLIKKTTDFEEIE--NVRNqQT-GNRKVYRFR 114
NP_001122338  80 NFRCALNKSDDFEEIKeRNVSDqQT-GNYKIYRLL 113
EEN50012      88 RLRNALRRLPDFAEQS-QHSRPdDPhDPFRVYKFV 121
EEN69106      98 RVRNALHRLKDFEEQT-DLGKPnDLqEPFRVYKLV 131
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